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The map label for this gene is pyrK [H]

Identifier: 57234038

GI number: 57234038

Start: 1100811

End: 1101596

Strand: Direct

Name: pyrK [H]

Synonym: DET1203

Alternate gene names: 57234038

Gene position: 1100811-1101596 (Clockwise)

Preceding gene: 57234039

Following gene: 57234025

Centisome position: 74.9

GC content: 55.09

Gene sequence:

>786_bases
GTGACAACTACCCAGCTAAACCAGCTTTCAGCCAGTGTAATTGAAAACGAAGAGGTCATGCCCGGCATCTGCCTGATGTG
GCTTGAAGCACCCGAAATAGCGGCTTCTGCCCGTCCGGGGCAGTTTGTCATGCTGTCCTGCGGCGGTGAAAACCTGCTGA
GGCGGCCTATTTCCATCCACCAGTGCCACCGGGAAAACGGGCTTATCGCCCTGATGTATGCCGTGGTGGGAAAAGGCACA
GACTGGCTCAGCAAACTTCAAACAGGAGACAGCCTTTCGGTGCTTGGCCCGTTGGGCAACGGCTTTCGGGTAAATGAGGA
CAGCCGTCACCTGCTGCTCCTGGGGGGCGGGCTGGGTATCGCCCCGCTCCGTTTTCTGGCAGACGAAGCTTTAAAACAAG
GCAAGCGGGTCAGCCTGATACAGGGTGCCAGAACCGAGCTTCAGGTCTGCCCTTCCCACTTGCTGCCGGAAGACGCCAGC
TGCCATGTCACCACTGAAAATGGGGCTATAGGCAAAAAAGGGCTTATTACCCACCATCTGGCGGAGTTTCTGCCGGATGC
AGACCAGATAATAGCCTGCGGGCCTATGCCCATGCTTAAGGCTCTGGCAAAAGAACCCCAGCTGTCAGGCAAGGACATAC
AGGTTTCCCTAGAAGTACGCATGGCCTGCGGTCTGGGTATCTGCTACGGCTGTGCCGTAAAAACAATCAAAGGCATGAAA
ACTGTCTGCCATGACGGGCCGGTATTTGATATACGGGATATCCACTGGGACGAAGTAAAAATATAA

Upstream 100 bases:

>100_bases
TAAAGCCGCAGTGGAAGCCTTAGCCAACGGCAACCGCCAGATAACGGTCTTGCCGCTGAATGAATACCGTCAGGGTAAAA
GCGGCAGTTAGGAAAGTATT

Downstream 100 bases:

>100_bases
CACCGTCACTGATTACCTGATAAATAAAAAGGGGCTTTAAAGCCCCTTTTTTAACATTGAGCAACAACCCTAGTGCTTTT
GCTGGATAAGTGAAAGAAAC

Product: dihydroorotate dehydrogenase, electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGENLLRRPISIHQCHRENGLIALMYAVVGKGT
DWLSKLQTGDSLSVLGPLGNGFRVNEDSRHLLLLGGGLGIAPLRFLADEALKQGKRVSLIQGARTELQVCPSHLLPEDAS
CHVTTENGAIGKKGLITHHLAEFLPDADQIIACGPMPMLKALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMK
TVCHDGPVFDIRDIHWDEVKI

Sequences:

>Translated_261_residues
MTTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGENLLRRPISIHQCHRENGLIALMYAVVGKGT
DWLSKLQTGDSLSVLGPLGNGFRVNEDSRHLLLLGGGLGIAPLRFLADEALKQGKRVSLIQGARTELQVCPSHLLPEDAS
CHVTTENGAIGKKGLITHHLAEFLPDADQIIACGPMPMLKALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMK
TVCHDGPVFDIRDIHWDEVKI
>Mature_260_residues
TTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGENLLRRPISIHQCHRENGLIALMYAVVGKGTD
WLSKLQTGDSLSVLGPLGNGFRVNEDSRHLLLLGGGLGIAPLRFLADEALKQGKRVSLIQGARTELQVCPSHLLPEDASC
HVTTENGAIGKKGLITHHLAEFLPDADQIIACGPMPMLKALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMKT
VCHDGPVFDIRDIHWDEVKI

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 28151; Mature: 28020

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGENLLRRPISIH
CCCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEEECCHHHHHCCCHHH
QCHRENGLIALMYAVVGKGTDWLSKLQTGDSLSVLGPLGNGFRVNEDSRHLLLLGGGLGI
HHHCCCCEEEEEEHHHCCCHHHHHHHCCCCCEEEEECCCCCEEECCCCCEEEEEECCCCH
APLRFLADEALKQGKRVSLIQGARTELQVCPSHLLPEDASCHVTTENGAIGKKGLITHHL
HHHHHHHHHHHHCCCEEEEECCCCHHHHHCHHHCCCCCCCEEEEECCCCCCCCCHHHHHH
AEFLPDADQIIACGPMPMLKALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMK
HHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHH
TVCHDGPVFDIRDIHWDEVKI
HHHCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
TTTQLNQLSASVIENEEVMPGICLMWLEAPEIAASARPGQFVMLSCGGENLLRRPISIH
CCCHHHHHHHHHHCCCCCCCCEEEEEECCCHHHCCCCCCCEEEEEECCHHHHHCCCHHH
QCHRENGLIALMYAVVGKGTDWLSKLQTGDSLSVLGPLGNGFRVNEDSRHLLLLGGGLGI
HHHCCCCEEEEEEHHHCCCHHHHHHHCCCCCEEEEECCCCCEEECCCCCEEEEEECCCCH
APLRFLADEALKQGKRVSLIQGARTELQVCPSHLLPEDASCHVTTENGAIGKKGLITHHL
HHHHHHHHHHHHCCCEEEEECCCCHHHHHCHHHCCCCCCCEEEEECCCCCCCCCHHHHHH
AEFLPDADQIIACGPMPMLKALAKEPQLSGKDIQVSLEVRMACGLGICYGCAVKTIKGMK
HHHCCCCCCEEEECCHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHH
TVCHDGPVFDIRDIHWDEVKI
HHHCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]