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The map label for this gene is fabD [H]

Identifier: 57233934

GI number: 57233934

Start: 1162357

End: 1163289

Strand: Direct

Name: fabD [H]

Synonym: DET1276

Alternate gene names: 57233934

Gene position: 1162357-1163289 (Clockwise)

Preceding gene: 57233942

Following gene: 57233933

Centisome position: 79.09

GC content: 51.88

Gene sequence:

>933_bases
ATGACTGAGATTAAAACAGCTTATGTCTTCCCCGGTCAGGGTGCCCAATTCGTGGGCATGGGCCGGGACTTGTATTCGGA
GTTTCATTCCGCCAGAGAGCTTTTTGACCTGGCGGATAAAGCTTTGGGATTTTCACTGTCAAAACTGTGTTTTGAAGGGC
CGGAAGAAGACCTTAAGGACACCCGCAACTCCCAAAGCGCCATTGTCGGCCACAGCCTGTGCGCCCTTGCTGCTTTTATA
GAGAGCGGCAAGTCAAATCTCCTGCCAGAGCCTTCTTTTGTAGCCGGGCATTCGCTGGGTGAATATTCGGCTTTGGGAGC
AGGCGGCATACTCCCCTACCCGCAGGCTATTTTGCTTGCCCGCAAACGGGGGGAACTGATGGCGGAAGCAGCCGCCAAAA
CACCCGGTGCTATGGCTGCCGTTCTCGGCCTTTCGGAAGAAATACTGGCGGATATCTGCCTTAAAACAGGCTGTTACATA
GCGAATTACAACTCCCCCGGACAGCTGGTTATCAGCGGCCTGAAAGAGACTGTAGAAAAAGCTTCTGCCCAAGCCGCAGA
GAGCGGTGCTATGAAGGTGGTACCCCTGCAGGTAAGCGGAGGGTTTCATACCCCGCTTATGTCACCGGCTTCTGCCGGTT
TAAAAGCAGTACTGGATTCTACCGGGTTTGATACGGCCAGAATACCTCTGGTAGCCAATACCAGCGCCAGCCCGCTTACC
AATCCGCAGGATATAAAAAGCGAACTGGTCAACCAGCTGACCGGCGGTGTCCAGTGGCAAAAAAGCATAGAAAACATGAT
TGCTGCCGGGGTAAATACCTTTGTTGAGATTGGGCCGGGCAAAGTGCTGGCCGGACTGATTAAAAGAATTAACCGCAGTG
TCAGTATCTACAATATAAACGATGCCGCTTCTATCCAAAATTTTAGCGTATAA

Upstream 100 bases:

>100_bases
CTTACAACGGCCGGACAGTGGTTGATGTGGACGCCATAGCCAAGAAAAAAGCTGACAAATCCAAGGGTCAGCAGTAATTT
CTGTTGGCCGGTTTTAAGGC

Downstream 100 bases:

>100_bases
TGGGTAAGATGCTGAGTTTAGACGGCAAAACAGCCCTGATTACCGGCTCCGGCAGGGGCATAGGCAAAGCTATAGCTTTA
CGGTTTGCCGAAGCGGGGGC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MTEIKTAYVFPGQGAQFVGMGRDLYSEFHSARELFDLADKALGFSLSKLCFEGPEEDLKDTRNSQSAIVGHSLCALAAFI
ESGKSNLLPEPSFVAGHSLGEYSALGAGGILPYPQAILLARKRGELMAEAAAKTPGAMAAVLGLSEEILADICLKTGCYI
ANYNSPGQLVISGLKETVEKASAQAAESGAMKVVPLQVSGGFHTPLMSPASAGLKAVLDSTGFDTARIPLVANTSASPLT
NPQDIKSELVNQLTGGVQWQKSIENMIAAGVNTFVEIGPGKVLAGLIKRINRSVSIYNINDAASIQNFSV

Sequences:

>Translated_310_residues
MTEIKTAYVFPGQGAQFVGMGRDLYSEFHSARELFDLADKALGFSLSKLCFEGPEEDLKDTRNSQSAIVGHSLCALAAFI
ESGKSNLLPEPSFVAGHSLGEYSALGAGGILPYPQAILLARKRGELMAEAAAKTPGAMAAVLGLSEEILADICLKTGCYI
ANYNSPGQLVISGLKETVEKASAQAAESGAMKVVPLQVSGGFHTPLMSPASAGLKAVLDSTGFDTARIPLVANTSASPLT
NPQDIKSELVNQLTGGVQWQKSIENMIAAGVNTFVEIGPGKVLAGLIKRINRSVSIYNINDAASIQNFSV
>Mature_309_residues
TEIKTAYVFPGQGAQFVGMGRDLYSEFHSARELFDLADKALGFSLSKLCFEGPEEDLKDTRNSQSAIVGHSLCALAAFIE
SGKSNLLPEPSFVAGHSLGEYSALGAGGILPYPQAILLARKRGELMAEAAAKTPGAMAAVLGLSEEILADICLKTGCYIA
NYNSPGQLVISGLKETVEKASAQAAESGAMKVVPLQVSGGFHTPLMSPASAGLKAVLDSTGFDTARIPLVANTSASPLTN
PQDIKSELVNQLTGGVQWQKSIENMIAAGVNTFVEIGPGKVLAGLIKRINRSVSIYNINDAASIQNFSV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=30.4347826086957, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI41872631, Length=300, Percent_Identity=30.3333333333333, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787334, Length=303, Percent_Identity=39.9339933993399, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=28.5714285714286, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=25.1700680272109, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24665753, Length=309, Percent_Identity=32.3624595469256, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32465; Mature: 32334

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEIKTAYVFPGQGAQFVGMGRDLYSEFHSARELFDLADKALGFSLSKLCFEGPEEDLKD
CCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
TRNSQSAIVGHSLCALAAFIESGKSNLLPEPSFVAGHSLGEYSALGAGGILPYPQAILLA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCCCCHHHHHH
RKRGELMAEAAAKTPGAMAAVLGLSEEILADICLKTGCYIANYNSPGQLVISGLKETVEK
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
ASAQAAESGAMKVVPLQVSGGFHTPLMSPASAGLKAVLDSTGFDTARIPLVANTSASPLT
HHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
NPQDIKSELVNQLTGGVQWQKSIENMIAAGVNTFVEIGPGKVLAGLIKRINRSVSIYNIN
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHCCCEEEEECC
DAASIQNFSV
CCCCCCCCCC
>Mature Secondary Structure 
TEIKTAYVFPGQGAQFVGMGRDLYSEFHSARELFDLADKALGFSLSKLCFEGPEEDLKD
CCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHH
TRNSQSAIVGHSLCALAAFIESGKSNLLPEPSFVAGHSLGEYSALGAGGILPYPQAILLA
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCCCCCCCCHHHHHH
RKRGELMAEAAAKTPGAMAAVLGLSEEILADICLKTGCYIANYNSPGQLVISGLKETVEK
HHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHH
ASAQAAESGAMKVVPLQVSGGFHTPLMSPASAGLKAVLDSTGFDTARIPLVANTSASPLT
HHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCC
NPQDIKSELVNQLTGGVQWQKSIENMIAAGVNTFVEIGPGKVLAGLIKRINRSVSIYNIN
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHCCCEEEEECC
DAASIQNFSV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]