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The map label for this gene is clpB [H]

Identifier: 57233811

GI number: 57233811

Start: 1281621

End: 1284059

Strand: Direct

Name: clpB [H]

Synonym: DET1413

Alternate gene names: 57233811

Gene position: 1281621-1284059 (Clockwise)

Preceding gene: 57233812

Following gene: 57233810

Centisome position: 87.2

GC content: 53.46

Gene sequence:

>2439_bases
GTGAGACAGGAAAAATTTACCGAACAAGCCCAGGAAGCCCTCAGTGCTTCACAGATGCTGGTGCAGGAATACCAGCACAG
CCAATGGGACGTTGAACATGTGCTGCTGGCCCTTATCCGTCAGGAAAAGGGGCTGGTGGGTGAAATACTAAAAGAACTTA
AAGTAAGCTCAGAGGAAATAACCAAGCAGCTGGTGGACTCTTTAAAGCGTTCGCCCAAAGCGGTAGGCGGCAATATCCAG
ATATACCCCACCCCCCGTATTATAAACCTGCTGCAAACCGCCAACAACGAAGCAGAGCGCCTGCGGGACGAGTTTATCGG
CACGGAACATTTGCTGGTGGCCATTGCCGGAGATACCCAGGGAGAATCTGCCCGAATTTTGAAGCAGTTTGGTATTGACC
AGGAAAAAGTTTATTCCGCCCTCCAAAAAATACGGGGCGGACACAGGGTGACCGATGCCAGAGCCGAAAGCAAATACCGG
GCACTGGCCAAATACAGCCGCGACCTTACCGAACTGGCCAAACAGGGCAAAATAGACCCGGTAATAGGCCGTGACCAGGA
AATCCGCCGGGTTATGCAAATACTCTCCCGCCGCACCAAAAACAACCCGGTGATTGTGGGTGAAGCGGGCGTGGGCAAAA
CTGCCATTGCCGAAGGGGTTGCCCAGAAAATTGCGGATAATGACGTACCCGAATCCCTGCGTGACCGCAAGGTAATGGCC
CTGGATATGGGCGCTCTGGTTGCCGGAAGCAAGTTCCGCGGAGAGTTTGAAGAACGCCTCAAAGCGGTCATGGACGAGGT
GCGCCAATCCGCCGGAGAGATTATCCTTTTCATAGACGAAATCCATACCGTAGTCGGGGCGGGAGCGGCTGAGGGAGCTA
TAGATGCCTCAAATATGCTCAAACCGGCTTTGGCCAGAGGTGAACTTCAGACAATAGGGGCTACCACTCTGGATGACTAC
CGCAAATATATTGAGAAAGATACCGCTCTGGAGCGCCGTTTCCAGCCGGTGTTTGTAGACGAGCCTACAGTTGAACAGAC
TATTGAAATATTAAAGGGCATCAGACCCAAATACGAAGCCCACCATAAACTGAAAATAACTGACGCCGCTCTGGAGGCAG
CCGCCAGACTGTCCAGCCGCTATATAACCGAACGCCAGCTGCCGGACAAGGCGATAGACCTTATTGACGAGGCAGCCAGT
AAACTCCGGCTGGACAGCGAAAGCGCCCCGCCGGAAGTAAAAAAACTGGAAGATGAACTCCGCCAGGCAGGCATTGAGGA
AGAGGCCGCCTCCCAGCTTCAGGAATACGAAAAAGCGGCTGAACTCAAGGCTGAAAAGATGCGTCTTGAGGAAAAATTCA
ACACTGCCCGCGAGGATTGGCTGAAACAGGAGAAAATAGCCGAAGAAGTAACCGCCGAACAGATTACCACCTTGGTTTCG
TCTATGACCGGCATACCGGTCAGCCAGATGCTGGAAGGTGAGGCTTCCAAACTGCTGAATATGGAAGACCGCATCCACGA
GCGTATGGTAGACCAGGAGGAAGCGGTAAAAGCCGTAGCCGAAGCTATCCGCCGCAGCCGGGCCGGTCTTAAAGACCCGC
GCCGTCCCATCGGCAGCTTTTTGTTCTTAGGCCCGACCGGGGTTGGCAAAACCGAACTTGCCCGCAGCTTAGCCTGGTTT
TTGTTTGATGACGAAACCGCCATGGTCAGGCTGGACATGTCCGAATATCAGGAAAAACACACTGTTTCCCGTCTGGTAGG
TGCTCCCCCCGGATACGTGGGCTACGACGAAGGCGGGCAGCTGACTGAACTGGTTCGCCGCCGCCCGTACCGGGTTATCC
TGCTGGACGAAATTGAAAAAGCCCACCCGGATGTATACAACACCCTGCTCCAGCTGCTGGATGACGGCCGCCTGACAGAC
GGGCAGGGCAGAACGGTGGACTTTAAAAACACGGTTATCATTATGACCTCCAACGCAGGCATAGAAACTATCAAACGCGA
ATCTGCCCTGGGTTTTGCCGTCAGGACTGATGACTCCAAAACCCGCCATGACGGCTATGAACGCATGAAAGACAAGGTCA
TGGCCGAGGTTAAAAAGACCTTCCGCCCGGAGTTTATCAACCGGGTAGACGAAATAATTGTCTTCCATGAGCTGGCCGAA
GAACAGATACGCCAGATAGTGGATTTCATAATAAAAGATGTTTCCAAACGGCTTGAAGAACGCAAACTCAAGCTGGAGCT
GACCGATGCCGCCAAAGGCTGGCTGGCCAAGGTGGGTTATGACCCGGCCTTTGGTGCCAGACCCCTTCGCAGGGCCATTG
AAAGATACATAGAAAGCCCGCTGGCTGACAAGCTGCTTCGCAATGAGTTCAGCGAAAATGCTACAATACTGGTGGACAAG
GCGGATGAAGCCCTGAGTTTCAGCCAGAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
GTTGAAGTAATCTTAAACATGCGTAACCGCATTCAGGAGCTTATATCCGAAAACGAAGCCCTGAGGGAAGAAATACAATT
ACTCAGAGAGGAGTAAACCC

Downstream 100 bases:

>100_bases
TACCAGGAAGGCCTTGGATAGTGGATCTGCCCGAAGAAGACATCTCAATATATGAAACCGGTGCCGAGCTGAAAACCCGT
GCTTGGTTTAAAAGATGGGG

Product: chaperone ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 812; Mature: 812

Protein sequence:

>812_residues
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALIRQEKGLVGEILKELKVSSEEITKQLVDSLKRSPKAVGGNIQ
IYPTPRIINLLQTANNEAERLRDEFIGTEHLLVAIAGDTQGESARILKQFGIDQEKVYSALQKIRGGHRVTDARAESKYR
ALAKYSRDLTELAKQGKIDPVIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNMLKPALARGELQTIGATTLDDY
RKYIEKDTALERRFQPVFVDEPTVEQTIEILKGIRPKYEAHHKLKITDAALEAAARLSSRYITERQLPDKAIDLIDEAAS
KLRLDSESAPPEVKKLEDELRQAGIEEEAASQLQEYEKAAELKAEKMRLEEKFNTAREDWLKQEKIAEEVTAEQITTLVS
SMTGIPVSQMLEGEASKLLNMEDRIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSFLFLGPTGVGKTELARSLAWF
LFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQLTELVRRRPYRVILLDEIEKAHPDVYNTLLQLLDDGRLTD
GQGRTVDFKNTVIIMTSNAGIETIKRESALGFAVRTDDSKTRHDGYERMKDKVMAEVKKTFRPEFINRVDEIIVFHELAE
EQIRQIVDFIIKDVSKRLEERKLKLELTDAAKGWLAKVGYDPAFGARPLRRAIERYIESPLADKLLRNEFSENATILVDK
ADEALSFSQKAA

Sequences:

>Translated_812_residues
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALIRQEKGLVGEILKELKVSSEEITKQLVDSLKRSPKAVGGNIQ
IYPTPRIINLLQTANNEAERLRDEFIGTEHLLVAIAGDTQGESARILKQFGIDQEKVYSALQKIRGGHRVTDARAESKYR
ALAKYSRDLTELAKQGKIDPVIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNMLKPALARGELQTIGATTLDDY
RKYIEKDTALERRFQPVFVDEPTVEQTIEILKGIRPKYEAHHKLKITDAALEAAARLSSRYITERQLPDKAIDLIDEAAS
KLRLDSESAPPEVKKLEDELRQAGIEEEAASQLQEYEKAAELKAEKMRLEEKFNTAREDWLKQEKIAEEVTAEQITTLVS
SMTGIPVSQMLEGEASKLLNMEDRIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSFLFLGPTGVGKTELARSLAWF
LFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQLTELVRRRPYRVILLDEIEKAHPDVYNTLLQLLDDGRLTD
GQGRTVDFKNTVIIMTSNAGIETIKRESALGFAVRTDDSKTRHDGYERMKDKVMAEVKKTFRPEFINRVDEIIVFHELAE
EQIRQIVDFIIKDVSKRLEERKLKLELTDAAKGWLAKVGYDPAFGARPLRRAIERYIESPLADKLLRNEFSENATILVDK
ADEALSFSQKAA
>Mature_812_residues
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALIRQEKGLVGEILKELKVSSEEITKQLVDSLKRSPKAVGGNIQ
IYPTPRIINLLQTANNEAERLRDEFIGTEHLLVAIAGDTQGESARILKQFGIDQEKVYSALQKIRGGHRVTDARAESKYR
ALAKYSRDLTELAKQGKIDPVIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNMLKPALARGELQTIGATTLDDY
RKYIEKDTALERRFQPVFVDEPTVEQTIEILKGIRPKYEAHHKLKITDAALEAAARLSSRYITERQLPDKAIDLIDEAAS
KLRLDSESAPPEVKKLEDELRQAGIEEEAASQLQEYEKAAELKAEKMRLEEKFNTAREDWLKQEKIAEEVTAEQITTLVS
SMTGIPVSQMLEGEASKLLNMEDRIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSFLFLGPTGVGKTELARSLAWF
LFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQLTELVRRRPYRVILLDEIEKAHPDVYNTLLQLLDDGRLTD
GQGRTVDFKNTVIIMTSNAGIETIKRESALGFAVRTDDSKTRHDGYERMKDKVMAEVKKTFRPEFINRVDEIIVFHELAE
EQIRQIVDFIIKDVSKRLEERKLKLELTDAAKGWLAKVGYDPAFGARPLRRAIERYIESPLADKLLRNEFSENATILVDK
ADEALSFSQKAA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=37.8737541528239, Blast_Score=203, Evalue=5e-52,
Organism=Escherichia coli, GI1788943, Length=859, Percent_Identity=50.058207217695, Blast_Score=808, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=808, Percent_Identity=37.3762376237624, Blast_Score=530, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6320464, Length=708, Percent_Identity=47.1751412429379, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=874, Percent_Identity=39.9313501144165, Blast_Score=609, Evalue=1e-175,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91410; Mature: 91410

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALIRQEKGLVGEILKELKVSSEEI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
TKQLVDSLKRSPKAVGGNIQIYPTPRIINLLQTANNEAERLRDEFIGTEHLLVAIAGDTQ
HHHHHHHHHCCCHHCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCC
GESARILKQFGIDQEKVYSALQKIRGGHRVTDARAESKYRALAKYSRDLTELAKQGKIDP
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCEEHE
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNML
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELQTIGATTLDDYRKYIEKDTALERRFQPVFVDEPTVEQTIEILKGIRPKYEA
HHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHC
HHKLKITDAALEAAARLSSRYITERQLPDKAIDLIDEAASKLRLDSESAPPEVKKLEDEL
CCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RQAGIEEEAASQLQEYEKAAELKAEKMRLEEKFNTAREDWLKQEKIAEEVTAEQITTLVS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMTGIPVSQMLEGEASKLLNMEDRIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSF
HHCCCCHHHHHCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCE
LFLGPTGVGKTELARSLAWFLFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQ
EEECCCCCCHHHHHHHHHHHEECCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTELVRRRPYRVILLDEIEKAHPDVYNTLLQLLDDGRLTDGQGRTVDFKNTVIIMTSNAG
HHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCC
IETIKRESALGFAVRTDDSKTRHDGYERMKDKVMAEVKKTFRPEFINRVDEIIVFHELAE
HHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
EQIRQIVDFIIKDVSKRLEERKLKLELTDAAKGWLAKVGYDPAFGARPLRRAIERYIESP
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCH
LADKLLRNEFSENATILVDKADEALSFSQKAA
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCC
>Mature Secondary Structure
MRQEKFTEQAQEALSASQMLVQEYQHSQWDVEHVLLALIRQEKGLVGEILKELKVSSEEI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHH
TKQLVDSLKRSPKAVGGNIQIYPTPRIINLLQTANNEAERLRDEFIGTEHLLVAIAGDTQ
HHHHHHHHHCCCHHCCCCEEEECCHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCC
GESARILKQFGIDQEKVYSALQKIRGGHRVTDARAESKYRALAKYSRDLTELAKQGKIDP
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VIGRDQEIRRVMQILSRRTKNNPVIVGEAGVGKTAIAEGVAQKIADNDVPESLRDRKVMA
CCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCHHHHCCEEHE
LDMGALVAGSKFRGEFEERLKAVMDEVRQSAGEIILFIDEIHTVVGAGAAEGAIDASNML
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELQTIGATTLDDYRKYIEKDTALERRFQPVFVDEPTVEQTIEILKGIRPKYEA
HHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHC
HHKLKITDAALEAAARLSSRYITERQLPDKAIDLIDEAASKLRLDSESAPPEVKKLEDEL
CCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
RQAGIEEEAASQLQEYEKAAELKAEKMRLEEKFNTAREDWLKQEKIAEEVTAEQITTLVS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMTGIPVSQMLEGEASKLLNMEDRIHERMVDQEEAVKAVAEAIRRSRAGLKDPRRPIGSF
HHCCCCHHHHHCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCE
LFLGPTGVGKTELARSLAWFLFDDETAMVRLDMSEYQEKHTVSRLVGAPPGYVGYDEGGQ
EEECCCCCCHHHHHHHHHHHEECCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTELVRRRPYRVILLDEIEKAHPDVYNTLLQLLDDGRLTDGQGRTVDFKNTVIIMTSNAG
HHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCC
IETIKRESALGFAVRTDDSKTRHDGYERMKDKVMAEVKKTFRPEFINRVDEIIVFHELAE
HHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
EQIRQIVDFIIKDVSKRLEERKLKLELTDAAKGWLAKVGYDPAFGARPLRRAIERYIESP
HHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCH
LADKLLRNEFSENATILVDKADEALSFSQKAA
HHHHHHHHHHCCCCEEEEECCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]