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The map label for this gene is hypB [H]

Identifier: 57233777

GI number: 57233777

Start: 1301773

End: 1302426

Strand: Direct

Name: hypB [H]

Synonym: DET1431

Alternate gene names: 57233777

Gene position: 1301773-1302426 (Clockwise)

Preceding gene: 57233778

Following gene: 57233776

Centisome position: 88.57

GC content: 48.62

Gene sequence:

>654_bases
ATGAAAGTCAAAGTTCTTAAAAATATTACCGACATGAATGACCAGCTGGCTGCCAGAAACAAGGATATGTTTGCCGGAAA
AGGCATACTGGTGATAAATGTCATGTCTTCACCCGGCGCCGGTAAAACCAGCTTGCTTCTTAAAACTATTGAGCTGCTGG
GAGATGATGCCCGGGTGGGTGTGATAGAGGGTGATATAGCCTCAAGCGTAGATGCCGAAAAAATAGCCGCCACCGGTTCG
CAGGCTATTCAGATAAATACAGACGGGGGCTGCCATCTGGATGCCAACATGGTAGCCTCAGCCGCAGACGGGCTGGAACT
GGACAAGCTGGATATTATTTTTATTGAAAACGTGGGCAATCTGGTCTGCCCGGCCGGATTTCAGCTGGGCGAAGCCAAAA
GGGTAGTGCTGGCATCCGTGCCGGAGGGTGATGACAAACCCACCAAATACCCCTTTATGTTCAGGGATACAGACGTAATA
GTCATAACCAAAATGGATTACCTGCCGCTTAGTGATTTTAATATGGAATCCTTCCGCAAAACAGTACTGGGTCTCAACCC
GGACGTAAAAATAATTGAGCTTTCAGTAAGGAATGGCCAGGGGCTGGACGAATGGACAGCCTGGCTGAAAAGCAACCTCC
TCAAGGGGAAATAG

Upstream 100 bases:

>100_bases
CCTTCAGGGCAGCATGCACTGGTCTGCCCCAAATGTCAGGGCTGGAATGCCGAAGTGATAGCCGGCAACGAATTTTTTAT
TGAAAGCATTGAGGTAGATG

Downstream 100 bases:

>100_bases
ATGCCCGCACCTAAGCAAACCAAGCGGTTTGCCTTTGCCATCAGCGGGATTGTCCAGGGGGTGGGCTTCCGCCCCTTTGT
TTACCAGCTGGCCGCCAAAC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKVKVLKNITDMNDQLAARNKDMFAGKGILVINVMSSPGAGKTSLLLKTIELLGDDARVGVIEGDIASSVDAEKIAATGS
QAIQINTDGGCHLDANMVASAADGLELDKLDIIFIENVGNLVCPAGFQLGEAKRVVLASVPEGDDKPTKYPFMFRDTDVI
VITKMDYLPLSDFNMESFRKTVLGLNPDVKIIELSVRNGQGLDEWTAWLKSNLLKGK

Sequences:

>Translated_217_residues
MKVKVLKNITDMNDQLAARNKDMFAGKGILVINVMSSPGAGKTSLLLKTIELLGDDARVGVIEGDIASSVDAEKIAATGS
QAIQINTDGGCHLDANMVASAADGLELDKLDIIFIENVGNLVCPAGFQLGEAKRVVLASVPEGDDKPTKYPFMFRDTDVI
VITKMDYLPLSDFNMESFRKTVLGLNPDVKIIELSVRNGQGLDEWTAWLKSNLLKGK
>Mature_217_residues
MKVKVLKNITDMNDQLAARNKDMFAGKGILVINVMSSPGAGKTSLLLKTIELLGDDARVGVIEGDIASSVDAEKIAATGS
QAIQINTDGGCHLDANMVASAADGLELDKLDIIFIENVGNLVCPAGFQLGEAKRVVLASVPEGDDKPTKYPFMFRDTDVI
VITKMDYLPLSDFNMESFRKTVLGLNPDVKIIELSVRNGQGLDEWTAWLKSNLLKGK

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=205, Percent_Identity=48.2926829268293, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 23397; Mature: 23397

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVKVLKNITDMNDQLAARNKDMFAGKGILVINVMSSPGAGKTSLLLKTIELLGDDARVG
CEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
VIEGDIASSVDAEKIAATGSQAIQINTDGGCHLDANMVASAADGLELDKLDIIFIENVGN
EEECCCCCCCCHHHHHCCCCEEEEEECCCCCEECHHHHHHCCCCCEECCEEEEEEECCCC
LVCPAGFQLGEAKRVVLASVPEGDDKPTKYPFMFRDTDVIVITKMDYLPLSDFNMESFRK
EECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCEECCCCCHHHHHH
TVLGLNPDVKIIELSVRNGQGLDEWTAWLKSNLLKGK
HHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVKVLKNITDMNDQLAARNKDMFAGKGILVINVMSSPGAGKTSLLLKTIELLGDDARVG
CEEEEECCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
VIEGDIASSVDAEKIAATGSQAIQINTDGGCHLDANMVASAADGLELDKLDIIFIENVGN
EEECCCCCCCCHHHHHCCCCEEEEEECCCCCEECHHHHHHCCCCCEECCEEEEEEECCCC
LVCPAGFQLGEAKRVVLASVPEGDDKPTKYPFMFRDTDVIVITKMDYLPLSDFNMESFRK
EECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEECCCEEEEEEECCEECCCCCHHHHHH
TVLGLNPDVKIIELSVRNGQGLDEWTAWLKSNLLKGK
HHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]