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The map label for this gene is 57233607

Identifier: 57233607

GI number: 57233607

Start: 1440711

End: 1442294

Strand: Direct

Name: 57233607

Synonym: DET1608

Alternate gene names: NA

Gene position: 1440711-1442294 (Clockwise)

Preceding gene: 57233616

Following gene: 57233606

Centisome position: 98.03

GC content: 52.84

Gene sequence:

>1584_bases
ATGTTGGAATTCTTTATGGAGACAGCGCCGACAACAACTACCGGCCTGCCTTTATCTGCCATTCTGGCCATCTTTTTCAG
TTTTATTATAGGTATTGTCTTCGGCGGTATGGCCCTGTTTGTATTCAGGGGCTTTATTATGAACCGCCAGCTCCGTATCG
CCCAGCGCAAAGCAACCAAAATGCTGGCGGACTCCAAAGTGGAAGCTAAAGATGTGCTGGTGGAAGCCAAGCGCGAAGCT
GACAAGGCCCGCAATTCCGCCGAAGCTGAACTTAAAGAACGCCGTTCTGAACTGGCCAAGCAGGAAAACCGGGTTATGCA
GAAGACCGAAGCCCTGGACCGCAAGCTTGAAAACCTGGAACAGCGGGAACAGTCCTTAACCAACCGGGAAAAAAGTATTG
ATGAAACACAGTCCCAGATTGAAGAAATACGGACAGCCGAACTGAAGCGTCTGGAAGAAGTGGCCAGCATGACCACTGAA
CAGGCCAAGTCAAGTTTGCTTGAGATGCTGGAAGGCGAAATGCAGCAGGAAACCTCCCGCCGATTGCGTGAGTGGGAGAT
AAAAATCAAGGCTGAAGCGGATGAAAAAGCCCGGGAGATTGTTTCCCAGGCTATCCAGCGCTGTGCCTCTGACGTAGTTA
CCGAAACCACTACCAATGTCGTACCCCTGCCCAGCGATGAAATGAAGGGCAGGCTGATTGGCCGCGAAGGCCGCAATATA
CGGGCGCTGGAACAGGCAACCGGAGTAGACCTTATTATAGATGACACCCCGGAGGCAGTTACTATCTCCAGTTTTGACCC
GGTACGGCGGGAAATTGCCAGACAGGCACTTTCCAAACTTATTATTGACGGGCGTATCCACCCGGCCCGCATTGAAGAAG
TGGTAGCAAAAGCCAAAGAGGAAGTGGAAGCCGCCATGATAGCTTCCGGCGAACAGGCCGCCTATCAGGCAGGCGTTCAC
GGACTGCGGCCTGAAATCATAAAGGTAATGGGGCGGCTGAAATACCGCACCAGTTACGGCCAGAACGTGCTTCAGCACAG
TATAGAGGTAGCCCAGATGTCCGGCATGATAGGCAGCGAGCTGGGGGTAAATGTTACCCTTGCCAGACGGGCCGGCTTCC
TGCATGACATAGGCAAAGCGGTTGACCGTGACGTGGAAGGCACCCATACCCAGATAGGCGCAGACATGGTCAAGCAGTGG
GAAAAATCACCCGAAGTTATCAAGGGTGTGGCTGAACACCACTTTGACACCCCCACCGTTTCCATCTGGGGTTTTATCGT
ATCTGCCGCAGATGCCATTTCTTCGGCCAGACCCGGTGCCCGCCGCGAATCACTGGAAAACTACATCAAACGCCTCAAGG
CTCTTGAAGAGATTGCCGACAGCTTCAAAGGGGTTGAAAAATCCTTTGCCATACAGGCAGGGCGCGAAGTGCGCATCATG
GTCAAACCTGAGGAGATTGATGACCTGGGTGCTATGCGGCTGGCCAGAGATATAGTCAAGAAGATTGAAGACGGGCTGGA
GTACCCCGGACAGATTAAGGTTACTGTTATCCGGGAAACCCGGTCTGTAGACTTTGCCAAGTAG

Upstream 100 bases:

>100_bases
GCGGAAACGGTAACACAGACGAATTGTAAGTCTTACATAGTTACGGCTCTCTGATACCCCCGTTGAAGAGAGCTTCTAAA
AGAAAGGGGTTTATATATAT

Downstream 100 bases:

>100_bases
GGCAGGTAGTAATGAAGATACTGGTAATCGGTGATGTCATCGGCAAGCCGGGGCGGGATGCCCTGCGGGATATCTTGCCG
GGACTGAAACAGGAATACAA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATKMLADSKVEAKDVLVEAKREA
DKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLEQREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTE
QAKSSLLEMLEGEMQQETSRRLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNI
RALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKEEVEAAMIASGEQAAYQAGVH
GLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSELGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQW
EKSPEVIKGVAEHHFDTPTVSIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIM
VKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK

Sequences:

>Translated_527_residues
MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATKMLADSKVEAKDVLVEAKREA
DKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLEQREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTE
QAKSSLLEMLEGEMQQETSRRLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNI
RALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKEEVEAAMIASGEQAAYQAGVH
GLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSELGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQW
EKSPEVIKGVAEHHFDTPTVSIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIM
VKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK
>Mature_527_residues
MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATKMLADSKVEAKDVLVEAKREA
DKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLEQREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTE
QAKSSLLEMLEGEMQQETSRRLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNI
RALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKEEVEAAMIASGEQAAYQAGVH
GLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSELGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQW
EKSPEVIKGVAEHHFDTPTVSIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIM
VKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_DEHE1 (Q3Z646)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_182303.1
- ProteinModelPortal:   Q3Z646
- STRING:   Q3Z646
- GeneID:   3229069
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET1608
- NMPDR:   fig|243164.3.peg.1523
- TIGR:   DET1608
- eggNOG:   COG1418
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   DETH243164:DET_1608-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58973; Mature: 58973

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe816d3c)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATK
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLADSKVEAKDVLVEAKREADKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLE
HHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTEQAKSSLLEMLEGEMQQETSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNI
HHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCEECCCCCCC
RALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKE
HHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EVEAAMIASGEQAAYQAGVHGLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSE
HHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
LGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQWEKSPEVIKGVAEHHFDTPTV
CCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
SIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH
>Mature Secondary Structure
MLEFFMETAPTTTTGLPLSAILAIFFSFIIGIVFGGMALFVFRGFIMNRQLRIAQRKATK
CCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLADSKVEAKDVLVEAKREADKARNSAEAELKERRSELAKQENRVMQKTEALDRKLENLE
HHHCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QREQSLTNREKSIDETQSQIEEIRTAELKRLEEVASMTTEQAKSSLLEMLEGEMQQETSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLREWEIKIKAEADEKAREIVSQAIQRCASDVVTETTTNVVPLPSDEMKGRLIGREGRNI
HHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCEECCCCCCC
RALEQATGVDLIIDDTPEAVTISSFDPVRREIARQALSKLIIDGRIHPARIEEVVAKAKE
HHHHHHCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EVEAAMIASGEQAAYQAGVHGLRPEIIKVMGRLKYRTSYGQNVLQHSIEVAQMSGMIGSE
HHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHC
LGVNVTLARRAGFLHDIGKAVDRDVEGTHTQIGADMVKQWEKSPEVIKGVAEHHFDTPTV
CCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHH
SIWGFIVSAADAISSARPGARRESLENYIKRLKALEEIADSFKGVEKSFAIQAGREVRIM
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VKPEEIDDLGAMRLARDIVKKIEDGLEYPGQIKVTVIRETRSVDFAK
ECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA