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The map label for this gene is lytH [H]

Identifier: 38234908

GI number: 38234908

Start: 2481613

End: 2482821

Strand: Direct

Name: lytH [H]

Synonym: DIP2375

Alternate gene names: 38234908

Gene position: 2481613-2482821 (Clockwise)

Preceding gene: 38234907

Following gene: NA

Centisome position: 99.72

GC content: 55.17

Gene sequence:

>1209_bases
ATGCATTTAGCGAAGGAAAGGAGCAGTGTGTCTGGCACGTTGAGAGTCGGCGACCGTAGCCCACGCATCGCCGAAGTCAG
AACTGCACTGACGCGACTTGGTCTGCTTGAGGGAACCACCAAGAACCTCGAGCAGACCAAAAGTGATACTTTCACCGATA
GCGAAACCCTGTTTGATGAGGACCTAGCGCTGGCGCTTCAGGGATTCCAGCAGGCTCGTGGCATTATTGCCAGCGGTGAG
ATCAACGAGATCACGTTGAAGCTCCTACGCGAAGCTTCCTATAGCCTCGGTGCACGTGTGTTGAGTTTTGAGCCCAACAA
TATTTTCGTGGGCGATGATGTTGTTCAGCTGCAGCATCAGCTCCAAGAGCTGGGCTTTTACACTGATCGTGTCGATGGCC
GCTTCGGCGAGCTGACGTACACGTCGCTAGTAAACTACCAGCTCAACTACGGGCTTAACCCCGATGGCATCTGCGGCCCC
GAAACCATTCGCGCTTTCGGCCGCCTAGGCCGCCGTATTACCGGCGGTTCCCCGCACGCTCTGCGAGAGCGCGAGCGAGT
TCGTGATGCCGGCCCAATGCTCGCCGGTAAGCGTGTGGTCATCGACCCAGGCTTTGGTGGTGCCGATAAGGGACAAGTTG
TTCGTGGTCCTTATGGCGATATCACGGAAGAAGAGATCATTTGGGATCTAGCGGGCCGTATCGAGGGCCGCATGATTGCC
GCTGGCATGGAAACTATTGTGTCGCGTCCGCGCCAGGATAGTCCTTCGCTGAAAGGTCGCGCAGACATCGCTAATGCATT
TGGTGCTGATGTGATGATTTCCTTGCAGTGCGATAAGTACCCGAATGATAAGGCCAATGGCGTTGCTAGCTTCTATTTCG
GTTCCGAGATGGGTTCTAGCTCGCTGACGGGCGAGATGTTGTCTGGCTTTATTCAGCGCGAAATTTCCGCGCGCACGGAT
CTGGTTAACTGCGGTAATCATGGTCGCACGTGGGATCTGCTGCGCATTACGGAGATGCCTACTGTGGAGGTTGTGTTGGG
TTATCTGACCAATCCGCACGACGTGGCTATTTTGACCGATCCTGAGCAGCGCGACGCTATCGCGGAAGCCATTGTGGTTG
CTGTTAAGCGTCTTTATTTGCTTGACGACGATGACCAGCCCACGGGCACGTATCGTTTCTCTGAGATGCTGGAGCAGGGT
TTGCTGTAG

Upstream 100 bases:

>100_bases
AGGACGGCCAGAAGGTTTCCGAATTTGTGGGAGTTCGTCCGAAATCTGAGATCGTGGCAAAGCTGCGTTCTTTTCTATGA
CTGCTAAACTTTCCTAAGTT

Downstream 100 bases:

>100_bases
CCCCTTAGCCCCCTGCACAGCACATAGCAAAGGGAGCCTCCTAGGAGGCTCCCTTTTTTAGTATGTTTTAGTGCTCTCCG
CCGAGTAGGCCCATGATGCG

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MHLAKERSSVSGTLRVGDRSPRIAEVRTALTRLGLLEGTTKNLEQTKSDTFTDSETLFDEDLALALQGFQQARGIIASGE
INEITLKLLREASYSLGARVLSFEPNNIFVGDDVVQLQHQLQELGFYTDRVDGRFGELTYTSLVNYQLNYGLNPDGICGP
ETIRAFGRLGRRITGGSPHALRERERVRDAGPMLAGKRVVIDPGFGGADKGQVVRGPYGDITEEEIIWDLAGRIEGRMIA
AGMETIVSRPRQDSPSLKGRADIANAFGADVMISLQCDKYPNDKANGVASFYFGSEMGSSSLTGEMLSGFIQREISARTD
LVNCGNHGRTWDLLRITEMPTVEVVLGYLTNPHDVAILTDPEQRDAIAEAIVVAVKRLYLLDDDDQPTGTYRFSEMLEQG
LL

Sequences:

>Translated_402_residues
MHLAKERSSVSGTLRVGDRSPRIAEVRTALTRLGLLEGTTKNLEQTKSDTFTDSETLFDEDLALALQGFQQARGIIASGE
INEITLKLLREASYSLGARVLSFEPNNIFVGDDVVQLQHQLQELGFYTDRVDGRFGELTYTSLVNYQLNYGLNPDGICGP
ETIRAFGRLGRRITGGSPHALRERERVRDAGPMLAGKRVVIDPGFGGADKGQVVRGPYGDITEEEIIWDLAGRIEGRMIA
AGMETIVSRPRQDSPSLKGRADIANAFGADVMISLQCDKYPNDKANGVASFYFGSEMGSSSLTGEMLSGFIQREISARTD
LVNCGNHGRTWDLLRITEMPTVEVVLGYLTNPHDVAILTDPEQRDAIAEAIVVAVKRLYLLDDDDQPTGTYRFSEMLEQG
LL
>Mature_402_residues
MHLAKERSSVSGTLRVGDRSPRIAEVRTALTRLGLLEGTTKNLEQTKSDTFTDSETLFDEDLALALQGFQQARGIIASGE
INEITLKLLREASYSLGARVLSFEPNNIFVGDDVVQLQHQLQELGFYTDRVDGRFGELTYTSLVNYQLNYGLNPDGICGP
ETIRAFGRLGRRITGGSPHALRERERVRDAGPMLAGKRVVIDPGFGGADKGQVVRGPYGDITEEEIIWDLAGRIEGRMIA
AGMETIVSRPRQDSPSLKGRADIANAFGADVMISLQCDKYPNDKANGVASFYFGSEMGSSSLTGEMLSGFIQREISARTD
LVNCGNHGRTWDLLRITEMPTVEVVLGYLTNPHDVAILTDPEQRDAIAEAIVVAVKRLYLLDDDDQPTGTYRFSEMLEQG
LL

Specific function: Probably involved in cell-wall metabolism [H]

COG id: COG0860

COG function: function code M; N-acetylmuramoyl-L-alanine amidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017273
- InterPro:   IPR002508
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01520 Amidase_3; PF08239 SH3_3 [H]

EC number: 3.5.1.28

Molecular weight: Translated: 44166; Mature: 44166

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLAKERSSVSGTLRVGDRSPRIAEVRTALTRLGLLEGTTKNLEQTKSDTFTDSETLFDE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHH
DLALALQGFQQARGIIASGEINEITLKLLREASYSLGARVLSFEPNNIFVGDDVVQLQHQ
HHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCHHHHHHHH
LQELGFYTDRVDGRFGELTYTSLVNYQLNYGLNPDGICGPETIRAFGRLGRRITGGSPHA
HHHCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHH
LRERERVRDAGPMLAGKRVVIDPGFGGADKGQVVRGPYGDITEEEIIWDLAGRIEGRMIA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEH
AGMETIVSRPRQDSPSLKGRADIANAFGADVMISLQCDKYPNDKANGVASFYFGSEMGSS
HHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCC
SLTGEMLSGFIQREISARTDLVNCGNHGRTWDLLRITEMPTVEVVLGYLTNPHDVAILTD
CCCHHHHHHHHHHHHHHHHCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEC
PEQRDAIAEAIVVAVKRLYLLDDDDQPTGTYRFSEMLEQGLL
CHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHLAKERSSVSGTLRVGDRSPRIAEVRTALTRLGLLEGTTKNLEQTKSDTFTDSETLFDE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHH
DLALALQGFQQARGIIASGEINEITLKLLREASYSLGARVLSFEPNNIFVGDDVVQLQHQ
HHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEECCHHHHHHHH
LQELGFYTDRVDGRFGELTYTSLVNYQLNYGLNPDGICGPETIRAFGRLGRRITGGSPHA
HHHCCCHHHCCCCCCCCEEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCHH
LRERERVRDAGPMLAGKRVVIDPGFGGADKGQVVRGPYGDITEEEIIWDLAGRIEGRMIA
HHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCEEEH
AGMETIVSRPRQDSPSLKGRADIANAFGADVMISLQCDKYPNDKANGVASFYFGSEMGSS
HHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCC
SLTGEMLSGFIQREISARTDLVNCGNHGRTWDLLRITEMPTVEVVLGYLTNPHDVAILTD
CCCHHHHHHHHHHHHHHHHCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEC
PEQRDAIAEAIVVAVKRLYLLDDDDQPTGTYRFSEMLEQGLL
CHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA