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The map label for this gene is azlC [H]

Identifier: 38234899

GI number: 38234899

Start: 2469436

End: 2470167

Strand: Reverse

Name: azlC [H]

Synonym: DIP2366

Alternate gene names: 38234899

Gene position: 2470167-2469436 (Counterclockwise)

Preceding gene: 38234900

Following gene: 38234898

Centisome position: 99.26

GC content: 57.51

Gene sequence:

>732_bases
GTGGTTTCACGTGAAACATCGAAAAAACGAACGGAGATTCTCGGCGGAATAAAAGACTCATGGGCGGTGGCCCTCGGTCT
CGTCCCCCTCGGCCTCGCCTTCGGGCTCGTGGTGGGACAATCCGGTTTTGCATGGTGGTGGGCCCCCATCTTTTCCATCA
TCATCTACGCGGGGTCCATGGAGTTCCTCGCACTGAACCTCATCCTTACCGGTGTTGGGCCTATCTCGGCGGCGATCACC
GGCTTTATGGTGAACTTTCGCCATATCTTTTATGGCCTCACCTACCCGCGCCACGCGGTGCGTTCCCGCATTGGTCGCGC
CTATTCCACGTACGCACTCACTGACGAGTCTTATGCAATCGTCTCGGCGCGCCCTAACGCGCAGCGTATCGACGGTTCCC
GCGTGCTCGCCATCCAAGTGTTCTGCCACGTAATGTGGGTATCCTCTGGCGTGCTTGGTGCCGTCGCCGGAAGCGCGATC
CCGCAGGGCCTAAAAGGCATGGAGTTTGCGCTCACCGCACTGTTTATCGTGTTGGCGTGGGAATCCTTCCGCAACAACCA
AGACTGGTCGTTGATATTTTTTGCCGTAGCCTTCTCACTCATCGGCCTAGGGCTGGTGCCACAACAAATGCTGATTTTTG
CTCTCGTGGTGTACTTCCTCTTGTTGCTGGTGCGTAACGCTTCCCCGCGTATCGACGCCCGATTGACCTGGAAGATCGGA
GATCGCCGGTGA

Upstream 100 bases:

>100_bases
GGCACCAGGAAGCGTTGATGTGTGGGGCGATGTGATGCGTCGTCAGCCCATGCCGTTGCCGTTGTATTCCACGTTCCCAG
TCAATGTGGGAGAAAACTAA

Downstream 100 bases:

>100_bases
ACTCCCCTATGAACCCATTAGTGCTCGCCGGTTCTGCGGGACTTCCCGATGGGATTAGTCTCCTGTCGGTCTTTGCGGTG
ATTATCCCCGTCGCCATAGT

Product: putative integral membrane amino acid transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MVSRETSKKRTEILGGIKDSWAVALGLVPLGLAFGLVVGQSGFAWWWAPIFSIIIYAGSMEFLALNLILTGVGPISAAIT
GFMVNFRHIFYGLTYPRHAVRSRIGRAYSTYALTDESYAIVSARPNAQRIDGSRVLAIQVFCHVMWVSSGVLGAVAGSAI
PQGLKGMEFALTALFIVLAWESFRNNQDWSLIFFAVAFSLIGLGLVPQQMLIFALVVYFLLLLVRNASPRIDARLTWKIG
DRR

Sequences:

>Translated_243_residues
MVSRETSKKRTEILGGIKDSWAVALGLVPLGLAFGLVVGQSGFAWWWAPIFSIIIYAGSMEFLALNLILTGVGPISAAIT
GFMVNFRHIFYGLTYPRHAVRSRIGRAYSTYALTDESYAIVSARPNAQRIDGSRVLAIQVFCHVMWVSSGVLGAVAGSAI
PQGLKGMEFALTALFIVLAWESFRNNQDWSLIFFAVAFSLIGLGLVPQQMLIFALVVYFLLLLVRNASPRIDARLTWKIG
DRR
>Mature_243_residues
MVSRETSKKRTEILGGIKDSWAVALGLVPLGLAFGLVVGQSGFAWWWAPIFSIIIYAGSMEFLALNLILTGVGPISAAIT
GFMVNFRHIFYGLTYPRHAVRSRIGRAYSTYALTDESYAIVSARPNAQRIDGSRVLAIQVFCHVMWVSSGVLGAVAGSAI
PQGLKGMEFALTALFIVLAWESFRNNQDWSLIFFAVAFSLIGLGLVPQQMLIFALVVYFLLLLVRNASPRIDARLTWKIG
DRR

Specific function: Involved in branched-chain amino acid transport [H]

COG id: COG1296

COG function: function code E; Predicted branched-chain amino acid permease (azaleucine resistance)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AzlC family [H]

Homologues:

Organism=Escherichia coli, GI1789038, Length=195, Percent_Identity=28.7179487179487, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004471
- InterPro:   IPR011606 [H]

Pfam domain/function: PF03591 AzlC [H]

EC number: NA

Molecular weight: Translated: 26749; Mature: 26749

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSRETSKKRTEILGGIKDSWAVALGLVPLGLAFGLVVGQSGFAWWWAPIFSIIIYAGSM
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCH
EFLALNLILTGVGPISAAITGFMVNFRHIFYGLTYPRHAVRSRIGRAYSTYALTDESYAI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEECCCCEEE
VSARPNAQRIDGSRVLAIQVFCHVMWVSSGVLGAVAGSAIPQGLKGMEFALTALFIVLAW
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ESFRNNQDWSLIFFAVAFSLIGLGLVPQQMLIFALVVYFLLLLVRNASPRIDARLTWKIG
HHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DRR
CCC
>Mature Secondary Structure
MVSRETSKKRTEILGGIKDSWAVALGLVPLGLAFGLVVGQSGFAWWWAPIFSIIIYAGSM
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCH
EFLALNLILTGVGPISAAITGFMVNFRHIFYGLTYPRHAVRSRIGRAYSTYALTDESYAI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHEEEECCCCEEE
VSARPNAQRIDGSRVLAIQVFCHVMWVSSGVLGAVAGSAIPQGLKGMEFALTALFIVLAW
EECCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ESFRNNQDWSLIFFAVAFSLIGLGLVPQQMLIFALVVYFLLLLVRNASPRIDARLTWKIG
HHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
DRR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]