| Definition | Corynebacterium diphtheriae NCTC 13129 chromosome, complete genome. |
|---|---|
| Accession | NC_002935 |
| Length | 2,488,635 |
Click here to switch to the map view.
The map label for this gene is dnaB [H]
Identifier: 38234823
GI number: 38234823
Start: 2384785
End: 2386305
Strand: Reverse
Name: dnaB [H]
Synonym: DIP2288
Alternate gene names: 38234823
Gene position: 2386305-2384785 (Counterclockwise)
Preceding gene: 38234824
Following gene: 38234819
Centisome position: 95.89
GC content: 55.23
Gene sequence:
>1521_bases ATGACCACGCCCAGTTTTGATGACGATTACGTCCCACCGGGTGATGCGGATGTTCCTTCCGATACCACAGATTATGCGGA GGCAGAGTACGCCGAGGTAGAGGTGTATGATCCGGCCCCGCCGGCTTCCTCGGATGTGCCAGTGCAGCGGGAGCGCAGGG GCTATAAGCGTCGTGAAGCGGCGATGGCGAGCACTGAGTTCCGTCAGCCTCCTCATGACGCGGAGGCTGAGCAGGGCGTG TTGGGGGCGATGCTGCTAAGCCCGCAAACGGTGATCGATACGGTGGAGTTGCTGGTTGCGGAGGATTTTTACCGCCCTGC GCATCAGTTGATTTTTGAGGCCATTGTTGGCTTGTTCTCCGATAACAAGGAGATCGACCCAGTGATCGTGGCTGCGCGTT TGGATCGTAATAATGATCTGGAACGTGTGGGCGGGGCACCGTATTTGCACACGCTGATCTCTTCGGTGCCGACTGCTGCG AATGCTCGTTATTATGCGGAAATTGTGGCTGAGAAGTCGTTGCTTCGTCAGCTGGTTAACGCTGGTACTCGTGTGGTGCA GTTGGGCTATGAGGGTACTGAGGGCGCTGAGGTTGAGTCGGTTATTGACCGTGCTCAGCAGGAAGTGTTCAAGGTTTCTA AGAAGAACCAAGCTGAGGATTATGCGGTGTTAGCTGACATCGTGGGTCCAACAATGGATGAGATCGATATGATCTCGGAG AATGGCGGCTTGGCGCAGGGCGTGCCGACGGGCTTTGTGGATCTAGATAACCTGACCAATGGTCTGCATGGTGGCCAGAT GATTATTGTGGCTGCCCGTCCGGGTGTGGGTAAGTCGACGATCGCGTTGGATTTTGTGCGTTCGTGTGCGATTAAGCATG ACAAGGCTGCTGTGATTTTCTCTTTGGAAATGTCAAAGAGTGAGATCGTGATGCGTTTGTTGTCGGCGGAGGCTGAGGTG AAGTTGTCGGATATGCGCTCTGGGCGTCTCGACGATTCCGGCTGGGCGAAGCTAGCAACACGCGTGGGACAGATCGAACA GGCGCCTATCTATATTGATGACTCCGCGAATTTGACGATGATGGAGATTCGCTCGAAGGCGCGTCGTTTGAAGCAGAAGC ATGATCTGCAGATGATTGTGGTGGACTACCTGCAGCTGATGAGCTCGGGTAAGCGTGTGGAGTCGCGTCAGCAAGAGGTG TCGGAGTTCTCGCGTCAGCTTAAGCTGCTGGCTAAGGAACTGGATGTTCCGCTTATTGCGATTTCACAGCTGAACCGTGG TCCGGAGTCGCGTACTGATAAGCGCCCGCAGCTTGCCGACCTGCGTGAATCCGGTTCGTTGGAGCAGGATGCCGACATGG TTATGCTGCTATACCGTCCAGACTCCCAAGATCGCGAGAATGAGCGCGCTGGTGAGGCCGATATTATTCTGGCTAAGCAC CGTGGTGGTCCTATCGACACCATCCAAGTGGCTCACCAGCTGCACTACTCGCGGTTTGTAGATATGCCGCACGCTGGCTA A
Upstream 100 bases:
>100_bases CCGGGGTAAAAATGCGTGTTGGAACGAAGATGAGTACGAACACGCACAAAGATCCCACAAGAAATAGTGATAAGGCCGTG TCGATGGAGGATGTGTAGGA
Downstream 100 bases:
>100_bases AGCCTAGACGAGGGCCTTGCCGCGTTGTTCGGGCAGGGTGAATGCGGCGATGGCTGCTGCAAGGAAGGCGGCCCCGAAGA GTGCGAAGAGCGCTGGGGTG
Product: replicative DNA helicase
Products: NA
Alternate protein names: Mbo dnaB intein [H]
Number of amino acids: Translated: 506; Mature: 505
Protein sequence:
>506_residues MTTPSFDDDYVPPGDADVPSDTTDYAEAEYAEVEVYDPAPPASSDVPVQRERRGYKRREAAMASTEFRQPPHDAEAEQGV LGAMLLSPQTVIDTVELLVAEDFYRPAHQLIFEAIVGLFSDNKEIDPVIVAARLDRNNDLERVGGAPYLHTLISSVPTAA NARYYAEIVAEKSLLRQLVNAGTRVVQLGYEGTEGAEVESVIDRAQQEVFKVSKKNQAEDYAVLADIVGPTMDEIDMISE NGGLAQGVPTGFVDLDNLTNGLHGGQMIIVAARPGVGKSTIALDFVRSCAIKHDKAAVIFSLEMSKSEIVMRLLSAEAEV KLSDMRSGRLDDSGWAKLATRVGQIEQAPIYIDDSANLTMMEIRSKARRLKQKHDLQMIVVDYLQLMSSGKRVESRQQEV SEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDRENERAGEADIILAKH RGGPIDTIQVAHQLHYSRFVDMPHAG
Sequences:
>Translated_506_residues MTTPSFDDDYVPPGDADVPSDTTDYAEAEYAEVEVYDPAPPASSDVPVQRERRGYKRREAAMASTEFRQPPHDAEAEQGV LGAMLLSPQTVIDTVELLVAEDFYRPAHQLIFEAIVGLFSDNKEIDPVIVAARLDRNNDLERVGGAPYLHTLISSVPTAA NARYYAEIVAEKSLLRQLVNAGTRVVQLGYEGTEGAEVESVIDRAQQEVFKVSKKNQAEDYAVLADIVGPTMDEIDMISE NGGLAQGVPTGFVDLDNLTNGLHGGQMIIVAARPGVGKSTIALDFVRSCAIKHDKAAVIFSLEMSKSEIVMRLLSAEAEV KLSDMRSGRLDDSGWAKLATRVGQIEQAPIYIDDSANLTMMEIRSKARRLKQKHDLQMIVVDYLQLMSSGKRVESRQQEV SEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDRENERAGEADIILAKH RGGPIDTIQVAHQLHYSRFVDMPHAG >Mature_505_residues TTPSFDDDYVPPGDADVPSDTTDYAEAEYAEVEVYDPAPPASSDVPVQRERRGYKRREAAMASTEFRQPPHDAEAEQGVL GAMLLSPQTVIDTVELLVAEDFYRPAHQLIFEAIVGLFSDNKEIDPVIVAARLDRNNDLERVGGAPYLHTLISSVPTAAN ARYYAEIVAEKSLLRQLVNAGTRVVQLGYEGTEGAEVESVIDRAQQEVFKVSKKNQAEDYAVLADIVGPTMDEIDMISEN GGLAQGVPTGFVDLDNLTNGLHGGQMIIVAARPGVGKSTIALDFVRSCAIKHDKAAVIFSLEMSKSEIVMRLLSAEAEVK LSDMRSGRLDDSGWAKLATRVGQIEQAPIYIDDSANLTMMEIRSKARRLKQKHDLQMIVVDYLQLMSSGKRVESRQQEVS EFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDRENERAGEADIILAKHR GGPIDTIQVAHQLHYSRFVDMPHAG
Specific function: The intein is an endonuclease (Potential) [H]
COG id: COG0305
COG function: function code L; Replicative DNA helicase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 SF4 helicase domain [H]
Homologues:
Organism=Escherichia coli, GI1790486, Length=459, Percent_Identity=39.8692810457516, Blast_Score=331, Evalue=7e-92,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR007692 - InterPro: IPR007694 - InterPro: IPR007693 - InterPro: IPR016136 - InterPro: IPR003586 - InterPro: IPR003587 - InterPro: IPR006142 - InterPro: IPR004042 - InterPro: IPR006141 [H]
Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 55860; Mature: 55729
Theoretical pI: Translated: 4.59; Mature: 4.59
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTTPSFDDDYVPPGDADVPSDTTDYAEAEYAEVEVYDPAPPASSDVPVQRERRGYKRREA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH AMASTEFRQPPHDAEAEQGVLGAMLLSPQTVIDTVELLVAEDFYRPAHQLIFEAIVGLFS HHHHHHCCCCCCCCCHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC DNKEIDPVIVAARLDRNNDLERVGGAPYLHTLISSVPTAANARYYAEIVAEKSLLRQLVN CCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH AGTRVVQLGYEGTEGAEVESVIDRAQQEVFKVSKKNQAEDYAVLADIVGPTMDEIDMISE CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHC NGGLAQGVPTGFVDLDNLTNGLHGGQMIIVAARPGVGKSTIALDFVRSCAIKHDKAAVIF CCCCCCCCCCCCEEHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEE SLEMSKSEIVMRLLSAEAEVKLSDMRSGRLDDSGWAKLATRVGQIEQAPIYIDDSANLTM EEECCHHHHHHHHHHHHCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEH MEIRSKARRLKQKHDLQMIVVDYLQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIA HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE ISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDRENERAGEADIILAKH HHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCEEEEEEC RGGPIDTIQVAHQLHYSRFVDMPHAG CCCCHHHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure TTPSFDDDYVPPGDADVPSDTTDYAEAEYAEVEVYDPAPPASSDVPVQRERRGYKRREA CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH AMASTEFRQPPHDAEAEQGVLGAMLLSPQTVIDTVELLVAEDFYRPAHQLIFEAIVGLFS HHHHHHCCCCCCCCCHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC DNKEIDPVIVAARLDRNNDLERVGGAPYLHTLISSVPTAANARYYAEIVAEKSLLRQLVN CCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH AGTRVVQLGYEGTEGAEVESVIDRAQQEVFKVSKKNQAEDYAVLADIVGPTMDEIDMISE CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHC NGGLAQGVPTGFVDLDNLTNGLHGGQMIIVAARPGVGKSTIALDFVRSCAIKHDKAAVIF CCCCCCCCCCCCEEHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEE SLEMSKSEIVMRLLSAEAEVKLSDMRSGRLDDSGWAKLATRVGQIEQAPIYIDDSANLTM EEECCHHHHHHHHHHHHCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCEEH MEIRSKARRLKQKHDLQMIVVDYLQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIA HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEE ISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDRENERAGEADIILAKH HHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHCCCCCEEEEEEC RGGPIDTIQVAHQLHYSRFVDMPHAG CCCCHHHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]