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The map label for this gene is trxC [C]

Identifier: 38234819

GI number: 38234819

Start: 2380171

End: 2380554

Strand: Reverse

Name: trxC [C]

Synonym: DIP2284

Alternate gene names: 38234819

Gene position: 2380554-2380171 (Counterclockwise)

Preceding gene: 38234823

Following gene: 38234818

Centisome position: 95.66

GC content: 54.43

Gene sequence:

>384_bases
ATGGCAACTATCGACGTCACCGAAGACACTTTCGAGCAGACCGTTACCAAAGACGGCATCGTGCTGGTCGACGCGTGGGC
TTCTTGGTGTGGACCATGCCGTGCATTCGCCCCCACCTACGAAAAGGCCTCCGAAAACCACCCAGACGCCGTATTTACCA
AGCTTGATACCGAAGCAAATCAAGGTCTTGCTGCAGCCTTGCAGATCCAGTCCATTCCAACCTTGATGGTGTTCCGCGAT
GGCATCATGGTCTACCGTGAGGCAGGCGCTTTGCCACCAGCAGCTCTAGAAGACCTGATCACTCAGGTGAAGGGCTTGGA
CATGGAAGACGTGAAGCGTCAGATCGCTGAGCAAAACGCTCAAAGCGACAGTGCTGAACTCTAA

Upstream 100 bases:

>100_bases
CTCGAGTGATCTTGCGGTAATGAGGCCCAGTGGGAATAAGAATGGGGGTACCGTAGTTGAGAAGCACGAAACCTCTAAAA
ACTTTAACGAAGGAGCATAC

Downstream 100 bases:

>100_bases
GAAATAGCTAACCCCCTGTACTGTACCCCCTTATGGGGGTTTACTTTTATCTGTATCTCATTGTTGTTCTGGTTCATGTC
ATACAAAAACGTCGTAAACT

Product: putative thioredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MATIDVTEDTFEQTVTKDGIVLVDAWASWCGPCRAFAPTYEKASENHPDAVFTKLDTEANQGLAAALQIQSIPTLMVFRD
GIMVYREAGALPPAALEDLITQVKGLDMEDVKRQIAEQNAQSDSAEL

Sequences:

>Translated_127_residues
MATIDVTEDTFEQTVTKDGIVLVDAWASWCGPCRAFAPTYEKASENHPDAVFTKLDTEANQGLAAALQIQSIPTLMVFRD
GIMVYREAGALPPAALEDLITQVKGLDMEDVKRQIAEQNAQSDSAEL
>Mature_126_residues
ATIDVTEDTFEQTVTKDGIVLVDAWASWCGPCRAFAPTYEKASENHPDAVFTKLDTEANQGLAAALQIQSIPTLMVFRDG
IMVYREAGALPPAALEDLITQVKGLDMEDVKRQIAEQNAQSDSAEL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758304, Length=83, Percent_Identity=37.3493975903614, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1788936, Length=101, Percent_Identity=37.6237623762376, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI87082331, Length=99, Percent_Identity=39.3939393939394, Blast_Score=77, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17510299, Length=105, Percent_Identity=37.1428571428571, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554386, Length=80, Percent_Identity=35, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=94, Percent_Identity=39.3617021276596, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321648, Length=86, Percent_Identity=39.5348837209302, Blast_Score=74, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319925, Length=87, Percent_Identity=29.8850574712644, Blast_Score=62, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658597, Length=85, Percent_Identity=36.4705882352941, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 13831; Mature: 13699

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDVTEDTFEQTVTKDGIVLVDAWASWCGPCRAFAPTYEKASENHPDAVFTKLDTEAN
CCEECCCHHHHHHHHCCCCEEEEECHHHHCCHHHHCCCCHHHHCCCCCCHHHHCCCCCCC
QGLAAALQIQSIPTLMVFRDGIMVYREAGALPPAALEDLITQVKGLDMEDVKRQIAEQNA
CCHHHHHHHCCCCCHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCC
QSDSAEL
CCCCCCC
>Mature Secondary Structure 
ATIDVTEDTFEQTVTKDGIVLVDAWASWCGPCRAFAPTYEKASENHPDAVFTKLDTEAN
CEECCCHHHHHHHHCCCCEEEEECHHHHCCHHHHCCCCHHHHCCCCCCHHHHCCCCCCC
QGLAAALQIQSIPTLMVFRDGIMVYREAGALPPAALEDLITQVKGLDMEDVKRQIAEQNA
CCHHHHHHHCCCCCHHHHHCCHHEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCC
QSDSAEL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8652661 [H]