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The map label for this gene is yhcG [H]

Identifier: 38234815

GI number: 38234815

Start: 2376306

End: 2377175

Strand: Reverse

Name: yhcG [H]

Synonym: DIP2279

Alternate gene names: 38234815

Gene position: 2377175-2376306 (Counterclockwise)

Preceding gene: 38234816

Following gene: 38234814

Centisome position: 95.52

GC content: 59.2

Gene sequence:

>870_bases
ATGACCACGATTCATGTCAGTGACCTGTCCAAAACCTACGGCACGGACACCAATGTGCCAGTTCTGAGCGGCGTCTCCTT
CGACCTCACCTCGCCTGCTATCCATGGTCTTATCGGTGCGAATGGCGTGGGAAAGACAACCCTGCTGAGGATCCTTGCAG
GTCAGTCGCGGTGCGAGGGTGTCGTCGAGGTCGACGGCCAACCCGCCTTTGATAACCCAGAAGTGATGGATCGTTGCGTG
CTCATGGGTATCGACGTCCCCCTCCCGTCCACATGGCGCGGAACAAAGCTCCTATCCTTCGCCCAGCATCGGTATCCGCG
TTGGGACGAGGCTCGCTGCGCGCAGCTTATCGACGCCTTCCAGGTGCCCGTCGATAAGCCCTACCAGTCGCTGTCCCGCG
GCCAGAAATCCGCACTCGGTATCATCATCGCCTTCAGTGCCACCTGCGACATCACGCTTCTCGACGAGCCCTACCTCGGA
CTCGACGTAGCCAACCGCGACCTTTTCTACCGTGAACTCCGCGCGGAACAAGCACGCTGCCCACGACTTATCATCCTGTC
CACCCACCACATCAACGAGGCCTCCCACGTTTTCGACTCCGTCATGGTGCTCAAAAAAGATGGCGTGGCCCTCCAAGGTG
ACGTGGAATCCATTACCGGACGCGTTGTAGAACTAGTCGGCCCCAAAGCCACGATCGAAGGCTTCGTTTCTCACCCTGCG
CGTCGAATTGGCGAGGTACACACAGCCGGTGGCGTGGCAAAAGTCCTAGCAGAAGCTCGTGCCGAGGAATGGGATCAGCT
CAGCGCCCTTGGCCTGCGAACCCACGAAGTTTCGCTCGAACGCGCCGTGATGTTCCTGGAGTGTGATTGA

Upstream 100 bases:

>100_bases
ATCTCGCCCCGCTTGTCGACGAAGCCGTCAAACTCACCATCTCTAAAACCGAACTCCACAACCTCATTGACCGAGTAGCA
GAAAGCCGAGGACTCTACGA

Downstream 100 bases:

>100_bases
TATGCGCATGTCCACCTCGTACCGAATACTCCGCCTCATGTCTCGAGGATCAATGCTTAGTTGCATCATGGTTGTTGTGG
TGTGGCTATTCGCTTGGGCA

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTTIHVSDLSKTYGTDTNVPVLSGVSFDLTSPAIHGLIGANGVGKTTLLRILAGQSRCEGVVEVDGQPAFDNPEVMDRCV
LMGIDVPLPSTWRGTKLLSFAQHRYPRWDEARCAQLIDAFQVPVDKPYQSLSRGQKSALGIIIAFSATCDITLLDEPYLG
LDVANRDLFYRELRAEQARCPRLIILSTHHINEASHVFDSVMVLKKDGVALQGDVESITGRVVELVGPKATIEGFVSHPA
RRIGEVHTAGGVAKVLAEARAEEWDQLSALGLRTHEVSLERAVMFLECD

Sequences:

>Translated_289_residues
MTTIHVSDLSKTYGTDTNVPVLSGVSFDLTSPAIHGLIGANGVGKTTLLRILAGQSRCEGVVEVDGQPAFDNPEVMDRCV
LMGIDVPLPSTWRGTKLLSFAQHRYPRWDEARCAQLIDAFQVPVDKPYQSLSRGQKSALGIIIAFSATCDITLLDEPYLG
LDVANRDLFYRELRAEQARCPRLIILSTHHINEASHVFDSVMVLKKDGVALQGDVESITGRVVELVGPKATIEGFVSHPA
RRIGEVHTAGGVAKVLAEARAEEWDQLSALGLRTHEVSLERAVMFLECD
>Mature_288_residues
TTIHVSDLSKTYGTDTNVPVLSGVSFDLTSPAIHGLIGANGVGKTTLLRILAGQSRCEGVVEVDGQPAFDNPEVMDRCVL
MGIDVPLPSTWRGTKLLSFAQHRYPRWDEARCAQLIDAFQVPVDKPYQSLSRGQKSALGIIIAFSATCDITLLDEPYLGL
DVANRDLFYRELRAEQARCPRLIILSTHHINEASHVFDSVMVLKKDGVALQGDVESITGRVVELVGPKATIEGFVSHPAR
RIGEVHTAGGVAKVLAEARAEEWDQLSALGLRTHEVSLERAVMFLECD

Specific function: Part Of The Abc Transporter Complex Cysawtp Involved In Sulfate/Thiosulfate Import. Responsible For Energy Coupling To The Transport System. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=209, Percent_Identity=30.1435406698565, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007184, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 31529; Mature: 31398

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIHVSDLSKTYGTDTNVPVLSGVSFDLTSPAIHGLIGANGVGKTTLLRILAGQSRCEG
CCEEEECCCHHHCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCE
VVEVDGQPAFDNPEVMDRCVLMGIDVPLPSTWRGTKLLSFAQHRYPRWDEARCAQLIDAF
EEEECCCCCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
QVPVDKPYQSLSRGQKSALGIIIAFSATCDITLLDEPYLGLDVANRDLFYRELRAEQARC
CCCCCCHHHHHHCCCCCCEEEEEEEECEEEEEECCCCCCCCEECCCHHHHHHHHHHHHCC
PRLIILSTHHINEASHVFDSVMVLKKDGVALQGDVESITGRVVELVGPKATIEGFVSHPA
CEEEEEEECCCCHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHH
RRIGEVHTAGGVAKVLAEARAEEWDQLSALGLRTHEVSLERAVMFLECD
HHHCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEEEEEECC
>Mature Secondary Structure 
TTIHVSDLSKTYGTDTNVPVLSGVSFDLTSPAIHGLIGANGVGKTTLLRILAGQSRCEG
CEEEECCCHHHCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCE
VVEVDGQPAFDNPEVMDRCVLMGIDVPLPSTWRGTKLLSFAQHRYPRWDEARCAQLIDAF
EEEECCCCCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHH
QVPVDKPYQSLSRGQKSALGIIIAFSATCDITLLDEPYLGLDVANRDLFYRELRAEQARC
CCCCCCHHHHHHCCCCCCEEEEEEEECEEEEEECCCCCCCCEECCCHHHHHHHHHHHHCC
PRLIILSTHHINEASHVFDSVMVLKKDGVALQGDVESITGRVVELVGPKATIEGFVSHPA
CEEEEEEECCCCHHHHHHHHHHEEECCCEEEECCHHHHHHHHHHHCCCHHHHHHHHHHHH
RRIGEVHTAGGVAKVLAEARAEEWDQLSALGLRTHEVSLERAVMFLECD
HHHCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]