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The map label for this gene is dasR [H]

Identifier: 38234777

GI number: 38234777

Start: 2331262

End: 2332098

Strand: Direct

Name: dasR [H]

Synonym: DIP2241

Alternate gene names: 38234777

Gene position: 2331262-2332098 (Clockwise)

Preceding gene: 38234770

Following gene: 38234778

Centisome position: 93.68

GC content: 59.26

Gene sequence:

>837_bases
GTGGTTCGGACCGCCCCAGACCCCGCAATGGTTCAAAGATCACACCAGAAACCCTCGCTGGTTATGACCACTCACAGTAT
GCTCATACCTATGGTCGACACTCTCCTGGAGTTGCCCGCCAGGACCCTGACTGACGGAACCAGCACTCCAAAACACCAGC
AACTCAGGGAAATTCTCGAAGAACTCTGCCGCACCCAGCTCAAACCTGGCGACATGCTCCCCGGCGAACGCGCCCTAGAG
GAGCAATACGGAGTTAGCCGCATCACGGTACGACGCGCCATCGGCGACCTCGTTGCCACCGGCCAACTGCGACGCAGCCG
CGGCAAAGGCACCTTCGTTGCCCAAGCCCCCATGATTACTCGGCTGCAGTTGGCGTCGTTTAGCGACGAAATGGCCGCCC
GCAAGATCGAAGCCTCCAGCAAGATCCTCGCATCCTCATGGTCTTCACCCAGCGCCGTCGTCCACGAATTTTTCGGCACC
GAACAAGGCACCCCGCACACCCACCTCGTGCGCGTCCGCCTCGGCGGCGGCAAACCATTTTGCATTAACGACGCCTGGTA
CAACTCCGCCATCGCACCTGACCTGCTCGAAAACGACGTATATAAATCCGTCTACTCCATCCTTGAGCAGAACTACGGCG
CATCTATTACCGGTGCCGAACAAATCACCACTGCGGTGGCCGCCACCCCAGAAACCGCGCGGATTCTCGGCGTGGATGTC
GGCGAACCACTACTGAAGGTGGAACGCCACGCACACGCAGGAGAAAACCCCATCGAGTGGTGTTCCTCGCTCTACCGCAC
CGACCGCTTCGCGTTAAGGACGTTTATCACGAAGTAG

Upstream 100 bases:

>100_bases
GCCACGAATGCGCTGGGACTCGCGGACGACATCAGGGTTTTCGCGGAGTAACTTTAGATCAATCACAAAACTTACACTAC
CGCGTTCCTGAGTTAAGAGG

Downstream 100 bases:

>100_bases
TATGGGCGAAATGAGTTCGAAAAAGGTTGCAGGTTTTGCAGGTGTGGCTGCCCTCGTAGTGGCTAGTGGCGTAGGCGCGT
ACACGTACACGGCGTCGCAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MVRTAPDPAMVQRSHQKPSLVMTTHSMLIPMVDTLLELPARTLTDGTSTPKHQQLREILEELCRTQLKPGDMLPGERALE
EQYGVSRITVRRAIGDLVATGQLRRSRGKGTFVAQAPMITRLQLASFSDEMAARKIEASSKILASSWSSPSAVVHEFFGT
EQGTPHTHLVRVRLGGGKPFCINDAWYNSAIAPDLLENDVYKSVYSILEQNYGASITGAEQITTAVAATPETARILGVDV
GEPLLKVERHAHAGENPIEWCSSLYRTDRFALRTFITK

Sequences:

>Translated_278_residues
MVRTAPDPAMVQRSHQKPSLVMTTHSMLIPMVDTLLELPARTLTDGTSTPKHQQLREILEELCRTQLKPGDMLPGERALE
EQYGVSRITVRRAIGDLVATGQLRRSRGKGTFVAQAPMITRLQLASFSDEMAARKIEASSKILASSWSSPSAVVHEFFGT
EQGTPHTHLVRVRLGGGKPFCINDAWYNSAIAPDLLENDVYKSVYSILEQNYGASITGAEQITTAVAATPETARILGVDV
GEPLLKVERHAHAGENPIEWCSSLYRTDRFALRTFITK
>Mature_278_residues
MVRTAPDPAMVQRSHQKPSLVMTTHSMLIPMVDTLLELPARTLTDGTSTPKHQQLREILEELCRTQLKPGDMLPGERALE
EQYGVSRITVRRAIGDLVATGQLRRSRGKGTFVAQAPMITRLQLASFSDEMAARKIEASSKILASSWSSPSAVVHEFFGT
EQGTPHTHLVRVRLGGGKPFCINDAWYNSAIAPDLLENDVYKSVYSILEQNYGASITGAEQITTAVAATPETARILGVDV
GEPLLKVERHAHAGENPIEWCSSLYRTDRFALRTFITK

Specific function: Global regulator that is part of the nutrient-sensing system. In the absence of N-acetylglucosamine 6-P, represses the phosphotransferase system (PTS) specific for the uptake of N- acetylglucosamine (PTSNag), and genes involved in the metabolism of chitin

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=229, Percent_Identity=30.1310043668122, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082252, Length=222, Percent_Identity=27.9279279279279, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790540, Length=229, Percent_Identity=27.9475982532751, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790118, Length=217, Percent_Identity=27.6497695852535, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 30652; Mature: 30652

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTAPDPAMVQRSHQKPSLVMTTHSMLIPMVDTLLELPARTLTDGTSTPKHQQLREILE
CCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHH
ELCRTQLKPGDMLPGERALEEQYGVSRITVRRAIGDLVATGQLRRSRGKGTFVAQAPMIT
HHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHH
RLQLASFSDEMAARKIEASSKILASSWSSPSAVVHEFFGTEQGTPHTHLVRVRLGGGKPF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCE
CINDAWYNSAIAPDLLENDVYKSVYSILEQNYGASITGAEQITTAVAATPETARILGVDV
EECHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCC
GEPLLKVERHAHAGENPIEWCSSLYRTDRFALRTFITK
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRTAPDPAMVQRSHQKPSLVMTTHSMLIPMVDTLLELPARTLTDGTSTPKHQQLREILE
CCCCCCCHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHH
ELCRTQLKPGDMLPGERALEEQYGVSRITVRRAIGDLVATGQLRRSRGKGTFVAQAPMIT
HHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHH
RLQLASFSDEMAARKIEASSKILASSWSSPSAVVHEFFGTEQGTPHTHLVRVRLGGGKPF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCE
CINDAWYNSAIAPDLLENDVYKSVYSILEQNYGASITGAEQITTAVAATPETARILGVDV
EECHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCC
GEPLLKVERHAHAGENPIEWCSSLYRTDRFALRTFITK
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]