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The map label for this gene is aniA [H]

Identifier: 38234446

GI number: 38234446

Start: 1918965

End: 1920353

Strand: Reverse

Name: aniA [H]

Synonym: DIP1876

Alternate gene names: 38234446

Gene position: 1920353-1918965 (Counterclockwise)

Preceding gene: 38234447

Following gene: 38234445

Centisome position: 77.16

GC content: 50.04

Gene sequence:

>1389_bases
ATGGAGACTAAAGAATCAACGTGGAGTGCTATTTGGGCGGTAGGCGGAGTCGCCGCAATTATGCTCGCCATCCTTGCTGG
TCTTGGATACGATACAGTTCGGACCGCTTTGATGACACGTCAGGAAGCTACGGTAGCCGCTCCTGTGAAACCTACTGGAG
AAACCACCGAAGTCACGGTTGTAGCAACAGAAAATATGAGTTACGAGCCTTCAGTTGTTGAGGTTCCAGTGGGCAATGAG
CTAATCATCAACTTAGTGAATAATGATCCGCACAATGGTCATGACCTTGTAGTTGGTGATAAGAAAACTGATCGAGTCGC
GCCGGGGAAATCCACCACATTAGACGTTGGATTAATCACTGAATCAATGACGGGCTTTTGTTCTGTTGCTGGGCATCGGC
AGATGGGAATGACCTTGCGTATCAACGCGGGGAGCCATGCGCATCATCAGCATGGTTCGCTATCTGAACATTTTCATCAG
TCGACACGGATTAGTGCTCCAATATCTCCAGTGTTGTCGCCCCTAGAACAGCGAACGACGTCTGTTACCCATGAGGCTAC
CTTCACTGTTTCTGAGGTTCCGCTAGAGGTTGCTCCTGGTGTATGGCAGACTAGGTGGACGTTTAATGGTTCTGGTGTTG
GTCCTACGCTGCATGGAAAAGTGGGAGACAAGTTCCGGATAACGCTGGTCAATAACGGAACCATTGGGCATTCGATTGAT
TTCCACGCAGGAGAGCTTGCTCCGGATGAGAAGATGCGCACAATTGGACCCGGGGAATCACTTATCTATGAATTCACTGC
AGGGCGCGCTGGAATATGGATGTACCACTGTTCGACGATGCCAATGGCAGCCCATATTGCCGCTGGTATGCATGGCGCGG
TTGTAATCGAGCCTGTAGATCTTGCACCGGTGGATAAGCAGTTCGTTTTGGTCCAATCTGAGGTTTATGTTGATTCGCCA
GCGTCTTCACCACAGGAAGCAACAGAGCTGCGTTCTGAGGCGATCGGATCTGAACCGCCAAACTACACGGTGTTTAACGG
TATTGCTTTCCAATACGATCAGGAAAAATTAGATGTCAAAGTTGGTGAGCGGGTACGTTTTTGGGTGCTCGATGCCGGTC
CTAATGTTCCACTTTCTTTCCATATTGTAGGTGGTCAGTTTGATACGACATGGACGGAAGGTGCATACACCCTCTATCGC
GGTTCAGGAGGGATTGCGGGAACACATGGCGTTGGTCATGATGGTGGTGCGCAAGTCCTGCCTTTGCTCCCAGCCCAAGG
GGGTTTTGTCGAATTGACTTTTGATGAACCGGGTAATTATGCCGTTGTTAATCACCTGATGAGCGAGGCAGAACGTGGCG
CTCGTGGCACGGTACGAGTAACTAAATAG

Upstream 100 bases:

>100_bases
TCGATGGTAGTAGGAATTCGAGAAAAGCGGCTCGTGGGCAGTAGTGAACAGCTGCCATCTTTACAACAACCATCATCGAA
TTTACTGAAGGGTCCTTCCC

Downstream 100 bases:

>100_bases
GGCTTGAAAAATTTATCTATTTTGAGGAGGAATACAGTAATGTCACTACCAATTTCGGAAAAGAAAGGTGGCTGCGGCTG
CGGTCACCATAACGAGACTC

Product: putative multicopper oxidase

Products: NA

Alternate protein names: Major outer membrane protein Pan 1 [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
METKESTWSAIWAVGGVAAIMLAILAGLGYDTVRTALMTRQEATVAAPVKPTGETTEVTVVATENMSYEPSVVEVPVGNE
LIINLVNNDPHNGHDLVVGDKKTDRVAPGKSTTLDVGLITESMTGFCSVAGHRQMGMTLRINAGSHAHHQHGSLSEHFHQ
STRISAPISPVLSPLEQRTTSVTHEATFTVSEVPLEVAPGVWQTRWTFNGSGVGPTLHGKVGDKFRITLVNNGTIGHSID
FHAGELAPDEKMRTIGPGESLIYEFTAGRAGIWMYHCSTMPMAAHIAAGMHGAVVIEPVDLAPVDKQFVLVQSEVYVDSP
ASSPQEATELRSEAIGSEPPNYTVFNGIAFQYDQEKLDVKVGERVRFWVLDAGPNVPLSFHIVGGQFDTTWTEGAYTLYR
GSGGIAGTHGVGHDGGAQVLPLLPAQGGFVELTFDEPGNYAVVNHLMSEAERGARGTVRVTK

Sequences:

>Translated_462_residues
METKESTWSAIWAVGGVAAIMLAILAGLGYDTVRTALMTRQEATVAAPVKPTGETTEVTVVATENMSYEPSVVEVPVGNE
LIINLVNNDPHNGHDLVVGDKKTDRVAPGKSTTLDVGLITESMTGFCSVAGHRQMGMTLRINAGSHAHHQHGSLSEHFHQ
STRISAPISPVLSPLEQRTTSVTHEATFTVSEVPLEVAPGVWQTRWTFNGSGVGPTLHGKVGDKFRITLVNNGTIGHSID
FHAGELAPDEKMRTIGPGESLIYEFTAGRAGIWMYHCSTMPMAAHIAAGMHGAVVIEPVDLAPVDKQFVLVQSEVYVDSP
ASSPQEATELRSEAIGSEPPNYTVFNGIAFQYDQEKLDVKVGERVRFWVLDAGPNVPLSFHIVGGQFDTTWTEGAYTLYR
GSGGIAGTHGVGHDGGAQVLPLLPAQGGFVELTFDEPGNYAVVNHLMSEAERGARGTVRVTK
>Mature_462_residues
METKESTWSAIWAVGGVAAIMLAILAGLGYDTVRTALMTRQEATVAAPVKPTGETTEVTVVATENMSYEPSVVEVPVGNE
LIINLVNNDPHNGHDLVVGDKKTDRVAPGKSTTLDVGLITESMTGFCSVAGHRQMGMTLRINAGSHAHHQHGSLSEHFHQ
STRISAPISPVLSPLEQRTTSVTHEATFTVSEVPLEVAPGVWQTRWTFNGSGVGPTLHGKVGDKFRITLVNNGTIGHSID
FHAGELAPDEKMRTIGPGESLIYEFTAGRAGIWMYHCSTMPMAAHIAAGMHGAVVIEPVDLAPVDKQFVLVQSEVYVDSP
ASSPQEATELRSEAIGSEPPNYTVFNGIAFQYDQEKLDVKVGERVRFWVLDAGPNVPLSFHIVGGQFDTTWTEGAYTLYR
GSGGIAGTHGVGHDGGAQVLPLLPAQGGFVELTFDEPGNYAVVNHLMSEAERGARGTVRVTK

Specific function: Catalyzes the reduction of nitrite to nitric oxide (NO), probably with azurin as electron donor. Essential for growth and survival in oxygen-depleted environments. Can also provide protection against killing by normal human sera [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 plastocyanin-like domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011707
- InterPro:   IPR008972
- InterPro:   IPR001287 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07732 Cu-oxidase_3 [H]

EC number: =1.7.2.1 [H]

Molecular weight: Translated: 49394; Mature: 49394

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKESTWSAIWAVGGVAAIMLAILAGLGYDTVRTALMTRQEATVAAPVKPTGETTEVTV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEE
VATENMSYEPSVVEVPVGNELIINLVNNDPHNGHDLVVGDKKTDRVAPGKSTTLDVGLIT
EEECCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEE
ESMTGFCSVAGHRQMGMTLRINAGSHAHHQHGSLSEHFHQSTRISAPISPVLSPLEQRTT
CCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
SVTHEATFTVSEVPLEVAPGVWQTRWTFNGSGVGPTLHGKVGDKFRITLVNNGTIGHSID
CCEEEEEEEEEECCHHHCCCCEEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCCEEC
FHAGELAPDEKMRTIGPGESLIYEFTAGRAGIWMYHCSTMPMAAHIAAGMHGAVVIEPVD
CCCCCCCCCCCCEECCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCCEEEEEECC
LAPVDKQFVLVQSEVYVDSPASSPQEATELRSEAIGSEPPNYTVFNGIAFQYDQEKLDVK
CCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECEEEEECCCEEEEE
VGERVRFWVLDAGPNVPLSFHIVGGQFDTTWTEGAYTLYRGSGGIAGTHGVGHDGGAQVL
ECCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEE
PLLPAQGGFVELTFDEPGNYAVVNHLMSEAERGARGTVRVTK
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEC
>Mature Secondary Structure
METKESTWSAIWAVGGVAAIMLAILAGLGYDTVRTALMTRQEATVAAPVKPTGETTEVTV
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCCCEEEEE
VATENMSYEPSVVEVPVGNELIINLVNNDPHNGHDLVVGDKKTDRVAPGKSTTLDVGLIT
EEECCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEE
ESMTGFCSVAGHRQMGMTLRINAGSHAHHQHGSLSEHFHQSTRISAPISPVLSPLEQRTT
CCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHH
SVTHEATFTVSEVPLEVAPGVWQTRWTFNGSGVGPTLHGKVGDKFRITLVNNGTIGHSID
CCEEEEEEEEEECCHHHCCCCEEEEEEECCCCCCCEEECCCCCEEEEEEEECCCCCCEEC
FHAGELAPDEKMRTIGPGESLIYEFTAGRAGIWMYHCSTMPMAAHIAAGMHGAVVIEPVD
CCCCCCCCCCCCEECCCCCCEEEEEECCCCEEEEEEECCCCHHHHHHCCCCCEEEEEECC
LAPVDKQFVLVQSEVYVDSPASSPQEATELRSEAIGSEPPNYTVFNGIAFQYDQEKLDVK
CCCCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECEEEEECCCEEEEE
VGERVRFWVLDAGPNVPLSFHIVGGQFDTTWTEGAYTLYRGSGGIAGTHGVGHDGGAQVL
ECCEEEEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEE
PLLPAQGGFVELTFDEPGNYAVVNHLMSEAERGARGTVRVTK
EEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1383156; 1398981 [H]