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The map label for this gene is serB [H]

Identifier: 38234433

GI number: 38234433

Start: 1906058

End: 1907290

Strand: Reverse

Name: serB [H]

Synonym: DIP1863

Alternate gene names: 38234433

Gene position: 1907290-1906058 (Counterclockwise)

Preceding gene: 38234434

Following gene: 38234432

Centisome position: 76.64

GC content: 53.61

Gene sequence:

>1233_bases
GTGCCGTTGCGCCAAGACCTCACCCCAGTTGTTATTACGGTGACTGGAGCCGACCGCCATGGTGTTACTGCTGCAACTTT
CCGTGTTCTTTCTGCGAACAATGTGCAGATTTTGGACGTGGAACAATCAAAGTTCCGTGGATTTTTGAGCATTGCCGTTT
ATGCCGGAATCAAAGCCTCGATGATCGATTCTGTTGAACAGGGGCTTCGCGACACGTTGAGTGTGCACGGTCAGTCTGTT
TCGCTTTCGGTGGAGTCTCGCACTGAGGTTTCGCGCCCTCGTTCGACCCACGTTGTGGTGATCTTGGGTAATCCTGTTGG
TGCTGAGGACATTTGGAAGATCGGTCAGACTATGGCTGATTTTGGTGCCAACATTGATGGCATTCGAGGGATTTCGGATT
ACCCTGTTACCGGTCTTGAGTTGCGCGTGACTGTGGCGGATCCTGCCCCTGGTGCGGCAGAGCCGTTGCGGAAGGCGCTG
GCTGCGTTGACAACCGAGTTGGGCGTTGACATCGTGATCGAACGCGCTGGTTTGCAGCGCCGCTCGAAGAGGTTGGTGTG
TTTTGATTGCGATTCCACGTTGATCACTGGTGAGGTCATTGAGATGTTGGCCGCGCATGCTGGTAGGGAAGAAGAAGTTG
CGGCGGTCACCGAGCGTGCGATGCGCGGCGAGCTTGATTTCGAGGAATCTCTGCGTGAGCGTGTGAAGGCGTTGGCTGGG
TTGGACGCTTCTGTTATCGACGAGGTTGCTCGCGATATTGTGCTTACTCCTGGCGCGCGTACCACGATTCGCACCCTGAA
GCGCTTGGGCTATAAGACGGCTGTGGTTTCGGGTGGATTTATCCAAGTTTTGGAAGATCTTGCCCAGGATTTGGATCTTG
ATTATGTTCGGGCAAATACCTTGGAAATCGAGGACGGCAAGTTGACGGGCCGCGTGATCGGTAAGGTAGTGGACCGTGCG
GCTAAGGCAGAGTTCCTGCGTGAGTTTGCTGGGGATTCTGGGCTTCGGATGTATCAGACTGTTGCTGTTGGTGATGGTGC
GAATGATATTGACATGATTTCGGCTGCAGGCATGGGCATTGCATTTAATGCGAAACCAGCGTTGCGAGAAGTCGCCGACA
CCTCGGTTAATACTCCTTTCCTTGATGAGGTCCTTTATATGTTGGGCATCACGCGCGAAGAAATCGATGCTGATGGGGAG
TCTCGTCGCGTTCCTTTGGAAGCACATGAGTAA

Upstream 100 bases:

>100_bases
TCCTAGGTCCTCGTTTTTGTGTTACCTAGTACAGGGGTGTTAATGGGATATGAGTCACAAATCATGCAACAATAGCGAGG
TGACTTCTCCAATAACTTCA

Downstream 100 bases:

>100_bases
TTTACGTATTGCTTATGACCGTTTGCGGTCGATGTCGCGGACGGAAGAAAACCCTACTGTTCAGGCGATGCAGATTGCTC
TTCATATTCCGAAGAATGAT

Product: putative hydrolase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MPLRQDLTPVVITVTGADRHGVTAATFRVLSANNVQILDVEQSKFRGFLSIAVYAGIKASMIDSVEQGLRDTLSVHGQSV
SLSVESRTEVSRPRSTHVVVILGNPVGAEDIWKIGQTMADFGANIDGIRGISDYPVTGLELRVTVADPAPGAAEPLRKAL
AALTTELGVDIVIERAGLQRRSKRLVCFDCDSTLITGEVIEMLAAHAGREEEVAAVTERAMRGELDFEESLRERVKALAG
LDASVIDEVARDIVLTPGARTTIRTLKRLGYKTAVVSGGFIQVLEDLAQDLDLDYVRANTLEIEDGKLTGRVIGKVVDRA
AKAEFLREFAGDSGLRMYQTVAVGDGANDIDMISAAGMGIAFNAKPALREVADTSVNTPFLDEVLYMLGITREEIDADGE
SRRVPLEAHE

Sequences:

>Translated_410_residues
MPLRQDLTPVVITVTGADRHGVTAATFRVLSANNVQILDVEQSKFRGFLSIAVYAGIKASMIDSVEQGLRDTLSVHGQSV
SLSVESRTEVSRPRSTHVVVILGNPVGAEDIWKIGQTMADFGANIDGIRGISDYPVTGLELRVTVADPAPGAAEPLRKAL
AALTTELGVDIVIERAGLQRRSKRLVCFDCDSTLITGEVIEMLAAHAGREEEVAAVTERAMRGELDFEESLRERVKALAG
LDASVIDEVARDIVLTPGARTTIRTLKRLGYKTAVVSGGFIQVLEDLAQDLDLDYVRANTLEIEDGKLTGRVIGKVVDRA
AKAEFLREFAGDSGLRMYQTVAVGDGANDIDMISAAGMGIAFNAKPALREVADTSVNTPFLDEVLYMLGITREEIDADGE
SRRVPLEAHE
>Mature_409_residues
PLRQDLTPVVITVTGADRHGVTAATFRVLSANNVQILDVEQSKFRGFLSIAVYAGIKASMIDSVEQGLRDTLSVHGQSVS
LSVESRTEVSRPRSTHVVVILGNPVGAEDIWKIGQTMADFGANIDGIRGISDYPVTGLELRVTVADPAPGAAEPLRKALA
ALTTELGVDIVIERAGLQRRSKRLVCFDCDSTLITGEVIEMLAAHAGREEEVAAVTERAMRGELDFEESLRERVKALAGL
DASVIDEVARDIVLTPGARTTIRTLKRLGYKTAVVSGGFIQVLEDLAQDLDLDYVRANTLEIEDGKLTGRVIGKVVDRAA
KAEFLREFAGDSGLRMYQTVAVGDGANDIDMISAAGMGIAFNAKPALREVADTSVNTPFLDEVLYMLGITREEIDADGES
RRVPLEAHE

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=202, Percent_Identity=30.1980198019802, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790849, Length=196, Percent_Identity=48.9795918367347, Blast_Score=172, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6321647, Length=229, Percent_Identity=44.5414847161572, Blast_Score=196, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24661601, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 44157; Mature: 44026

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRQDLTPVVITVTGADRHGVTAATFRVLSANNVQILDVEQSKFRGFLSIAVYAGIKAS
CCCCCCCCCEEEEEECCCCCCCCHHHEEEEECCCEEEEECCHHHHHHHHHHHHHHCCHHH
MIDSVEQGLRDTLSVHGQSVSLSVESRTEVSRPRSTHVVVILGNPVGAEDIWKIGQTMAD
HHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
FGANIDGIRGISDYPVTGLELRVTVADPAPGAAEPLRKALAALTTELGVDIVIERAGLQR
HCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHH
RSKRLVCFDCDSTLITGEVIEMLAAHAGREEEVAAVTERAMRGELDFEESLRERVKALAG
HCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
LDASVIDEVARDIVLTPGARTTIRTLKRLGYKTAVVSGGFIQVLEDLAQDLDLDYVRANT
CCHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHCCCCEEECCE
LEIEDGKLTGRVIGKVVDRAAKAEFLREFAGDSGLRMYQTVAVGDGANDIDMISAAGMGI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHCCCCE
AFNAKPALREVADTSVNTPFLDEVLYMLGITREEIDADGESRRVPLEAHE
EECCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLRQDLTPVVITVTGADRHGVTAATFRVLSANNVQILDVEQSKFRGFLSIAVYAGIKAS
CCCCCCCCEEEEEECCCCCCCCHHHEEEEECCCEEEEECCHHHHHHHHHHHHHHCCHHH
MIDSVEQGLRDTLSVHGQSVSLSVESRTEVSRPRSTHVVVILGNPVGAEDIWKIGQTMAD
HHHHHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
FGANIDGIRGISDYPVTGLELRVTVADPAPGAAEPLRKALAALTTELGVDIVIERAGLQR
HCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCHHH
RSKRLVCFDCDSTLITGEVIEMLAAHAGREEEVAAVTERAMRGELDFEESLRERVKALAG
HCCEEEEEECCCCEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
LDASVIDEVARDIVLTPGARTTIRTLKRLGYKTAVVSGGFIQVLEDLAQDLDLDYVRANT
CCHHHHHHHHHHEEECCCCHHHHHHHHHCCCHHEEECCHHHHHHHHHHHHCCCCEEECCE
LEIEDGKLTGRVIGKVVDRAAKAEFLREFAGDSGLRMYQTVAVGDGANDIDMISAAGMGI
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHCCCCE
AFNAKPALREVADTSVNTPFLDEVLYMLGITREEIDADGESRRVPLEAHE
EECCCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA