Click here to switch to the map view.

The map label for this gene is acpS [H]

Identifier: 38234415

GI number: 38234415

Start: 1883952

End: 1884335

Strand: Reverse

Name: acpS [H]

Synonym: DIP1845

Alternate gene names: 38234415

Gene position: 1884335-1883952 (Counterclockwise)

Preceding gene: 38234416

Following gene: 38234412

Centisome position: 75.72

GC content: 60.68

Gene sequence:

>384_bases
ATGATTGTTATTGGAACCGACATCGTGTGCATTCCCTCTTTTGCGCAGCAATTAGATCAGCCTGGTACGCAGTTTGACCG
GGTGTTTTCGGCCCAAGAGTTACGTGTTGCGGCACGCTATCAGGGGCGGCGGCGTGCCGAGCATTTGGCGGGGCGGTGGG
CTGCTAAGGAGGCGTTTGTTAAGGCGTGGTCGCAGTCGCTGTATGGCAAGCCACCGGTGTTGGAGCACGTCGATTGGGCT
GAGATCGAGGTGCAGCCGGACGCGTGGGGGCGGGTGCTGGTGGTGCCGCGTGGGGAGGTAGCGCGTGCTTGCGGAATTGA
GTGCGCGCAGGTGAGTATCAGCCATGACGGAAATTACGCCATGGCGCAGTGCGTGCTGGGCTAA

Upstream 100 bases:

>100_bases
GCGGTGCTGCTGAATGATTCCGCCCGCTTGGTTGACGGTGTGTATGTGGTTGATCCAGTAGCCTAAAGCTGGATCATAAA
AGCGAGAAGAGGGAATGTGC

Downstream 100 bases:

>100_bases
GCGGTGGCGACGGCGAAGAGGTAGGCCACAATCATCCGTTTGATTTCGGCTACGCGGGATTCGAAGACCTCGTCGCTGGA
AGTCGGGTCGTGCACAGCGT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MIVIGTDIVCIPSFAQQLDQPGTQFDRVFSAQELRVAARYQGRRRAEHLAGRWAAKEAFVKAWSQSLYGKPPVLEHVDWA
EIEVQPDAWGRVLVVPRGEVARACGIECAQVSISHDGNYAMAQCVLG

Sequences:

>Translated_127_residues
MIVIGTDIVCIPSFAQQLDQPGTQFDRVFSAQELRVAARYQGRRRAEHLAGRWAAKEAFVKAWSQSLYGKPPVLEHVDWA
EIEVQPDAWGRVLVVPRGEVARACGIECAQVSISHDGNYAMAQCVLG
>Mature_127_residues
MIVIGTDIVCIPSFAQQLDQPGTQFDRVFSAQELRVAARYQGRRRAEHLAGRWAAKEAFVKAWSQSLYGKPPVLEHVDWA
EIEVQPDAWGRVLVVPRGEVARACGIECAQVSISHDGNYAMAQCVLG

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 14051; Mature: 14051

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIGTDIVCIPSFAQQLDQPGTQFDRVFSAQELRVAARYQGRRRAEHLAGRWAAKEAFV
CEEECCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAWSQSLYGKPPVLEHVDWAEIEVQPDAWGRVLVVPRGEVARACGIECAQVSISHDGNYA
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHCCEEEEEEECCCCCEE
MAQCVLG
EEEEECC
>Mature Secondary Structure
MIVIGTDIVCIPSFAQQLDQPGTQFDRVFSAQELRVAARYQGRRRAEHLAGRWAAKEAFV
CEEECCCEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAWSQSLYGKPPVLEHVDWAEIEVQPDAWGRVLVVPRGEVARACGIECAQVSISHDGNYA
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHCCEEEEEEECCCCCEE
MAQCVLG
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]