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The map label for this gene is insK [H]

Identifier: 38234380

GI number: 38234380

Start: 1858843

End: 1859655

Strand: Direct

Name: insK [H]

Synonym: DIP1809

Alternate gene names: 38234380

Gene position: 1858843-1859655 (Clockwise)

Preceding gene: 38234379

Following gene: 38234382

Centisome position: 74.69

GC content: 51.78

Gene sequence:

>813_bases
TTGCTTGCCGTCTCTGGCCTGGCTAGGTCAACGTTTTTTGATCACCAGCGTCGTTTTGACCTGCCAGATAAGTACGCCGA
CCTCAAGGAACAGATTACGACGATCTTTCACGACTCCAACGCCACGTTTGGCTATCGCCGTATCTGGCGTGCGCTGCGCA
ACAACAACACGATCGTCAACAAGAAGGTGGTTCAAAGGCTCATGCGCGAGCAAGGATTGGTATCGAAGATCAGGCGTAAG
AAGTACAACTCCTACCGTGGCACTGTCAGCCACATTGCTGACAACGTGCTTGGCCGACGCTTCATCCAAGACGCACCGAA
CAAAGTGTGGGTTAGTGACGTCACAGAGTTCCGGGTAGCCGGCACCAAGGTATACCTGTCGCCAGTCATGGATCTGTTTG
ACCGAACCATCTTGGCGCATACTCTGTCTACGTCACCGAATACTCAGCTCACATCACGCTCGTTGGCCGATGCCATTGCC
ATGTTTAGTCCGGGTAAAGGACTGATTGTGCACACTGACCAAGGCTTTCAGTACCAACACGCAAGCTGGCGCACCCTGAT
TAAAAGCGTTGGCGGTGTGCAGTCAATGTCACGCAAAGGCAATTGCTACGACAACGCGGTGATGGAAAATTTCTTCGGAC
ACTTGAAATCAGAGATGTACTACGGCGCGTCTTTCACCAGTGTCGATGAGCTTTGCCAAGCTATCGATGAGTACATACTG
TGGTACAACACGTACCGACTCCAAGAACGATTCAAGGGTCTGGCTCCGATGCAATATCGGAACCAGACCCTTGCAAAGAC
CCTAACCGTTTAG

Upstream 100 bases:

>100_bases
AAGTGGCGTACCTAAAAAAATTGAGGGACTTGAGGGATCAACGACGAGGCTGAAAGTTGCGGCCATCATCACCCTCAAGT
CCGATCACCGCCTGGATGAC

Downstream 100 bases:

>100_bases
AATTAACCCAGTCCGGAAAACGGGGCTCAGTTCACATTGTGGGTCGTTTTTGTTATTCCACGTCTTTAAGCTTGTGCGAC
GTTGCAGCTCCTGCAAGCCC

Product: putative transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MLAVSGLARSTFFDHQRRFDLPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPVMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRTLIKSVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYYGASFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV

Sequences:

>Translated_270_residues
MLAVSGLARSTFFDHQRRFDLPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPVMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRTLIKSVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYYGASFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV
>Mature_270_residues
MLAVSGLARSTFFDHQRRFDLPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVNKKVVQRLMREQGLVSKIRRK
KYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVAGTKVYLSPVMDLFDRTILAHTLSTSPNTQLTSRSLADAIA
MFSPGKGLIVHTDQGFQYQHASWRTLIKSVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYYGASFTSVDELCQAIDEYIL
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=225, Percent_Identity=30.2222222222222, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1789981, Length=263, Percent_Identity=44.8669201520913, Blast_Score=247, Evalue=6e-67,
Organism=Escherichia coli, GI1788405, Length=236, Percent_Identity=33.8983050847458, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787263, Length=236, Percent_Identity=33.8983050847458, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786753, Length=236, Percent_Identity=33.8983050847458, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786570, Length=236, Percent_Identity=33.8983050847458, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786490, Length=236, Percent_Identity=33.8983050847458, Blast_Score=125, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31109; Mature: 31109

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVSGLARSTFFDHQRRFDLPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVN
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEC
KKVVQRLMREQGLVSKIRRKKYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHC
GTKVYLSPVMDLFDRTILAHTLSTSPNTQLTSRSLADAIAMFSPGKGLIVHTDQGFQYQH
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
ASWRTLIKSVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYYGASFTSVDELCQAIDEYIL
HHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAVSGLARSTFFDHQRRFDLPDKYADLKEQITTIFHDSNATFGYRRIWRALRNNNTIVN
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEC
KKVVQRLMREQGLVSKIRRKKYNSYRGTVSHIADNVLGRRFIQDAPNKVWVSDVTEFRVA
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHC
GTKVYLSPVMDLFDRTILAHTLSTSPNTQLTSRSLADAIAMFSPGKGLIVHTDQGFQYQH
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCH
ASWRTLIKSVGGVQSMSRKGNCYDNAVMENFFGHLKSEMYYGASFTSVDELCQAIDEYIL
HHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
WYNTYRLQERFKGLAPMQYRNQTLAKTLTV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]