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The map label for this gene is engA [H]

Identifier: 38233787

GI number: 38233787

Start: 1195725

End: 1197368

Strand: Direct

Name: engA [H]

Synonym: DIP1197

Alternate gene names: 38233787

Gene position: 1195725-1197368 (Clockwise)

Preceding gene: 38233786

Following gene: 38233788

Centisome position: 48.05

GC content: 49.15

Gene sequence:

>1644_bases
ATGAGCAATGCGCACAATGCACCGCTTGGCGGAAATAACTCCTCGGATGAAGACCAAGAAACGGTTTTCGTTTATCACAC
TGCACATGGTGAAGTCGATGCTCAGGAAGCATTCGTAGAAGAAGACGTCGTAGTCGATGGGGCTGGGTATGCTTCTGATG
GCTTTGATGAGAATGACTTTGACTTCGATTTTGAACATGACTCTGAAGGCAATGTCGTATTCGATGAAGCTGATTTTGGG
GAAGCCGACTTTGGTGAGGATTACACCGATGAAGATTGGGAAGAGCTTGAGCGTGCATTCGGTGTTGGATCTCGGGCGAT
TGAGTCAGAGAACCTCTGCACGGTGGCCATCGTAGGTCGTCCAAATGTTGGCAAGTCTTCGCTTGTTAATCGCTTTTTAG
GGCGCCGAGAAGCAGTGGTTGAGGACTTCCCCGGCGTTACGCGAGATCGAATTTCTTATCTAGCGGATTGGGGAGGACGT
CGATTCTGGGTTCAAGATACTGGTGGTTGGGATCCAAACGTTAAGGGGATCCACGCGGTGATTGCCCGGCAGGCGGAAAC
CGCGATGGCTACAGCAGACGTTATCGTTATGGTTGTCGATACCAAGGTGGGTATTACGGAAACCGATTCGGTGATGGCCC
GTAAACTTCAAAAATCTGAAGTTCCAGTAATTTTGGTGGCTAACAAATTTGATTCTGATAGCCAGTATGCCGATATGGCA
GAGTTTTATGCATTGGGTTTGGGAGACCCTTGGCCGGTTTCTGCGCAGCATGGTCGAGGCGGCGCAGACGTTCTCGAGCA
AATTTTGGCAGCATTCCCAGAAACCCCACGTGCAACCTCAATTGTTGAAGGACCGCGTCGCGTTGCCCTTGTGGGTAAAC
CCAATGTGGGCAAGTCATCTTTGCTAAATAAAATGTCTGGCGAAGATCGATCAGTTGTCGATAATGTATCCGGTACAACG
GTGGATCCGGTGGATTCCATCGTAAAACTTGACAAGCACCTTTGGAAGTTTATTGATACTGCGGGACTACGCAAAAAAGT
GAAAAATGCCCAAGGGCATGAGTATTACGCGTCTCTACGTACTCGTGGCGTTATTGATGCTGCTGAAATATGTATTTTCA
TGATCGATTCCTCGGAACCAGTCTCGGAGCAAGATCAACGTGTGTTGGCCATGATCTTGGATGCTGGTAAAGCGCTCGTC
CTTGTTTTCAACAAATGGGATCTTATGGAAGAAGATCGCCGTTGGGAACTAGAACGTGAAATTGATCTGCAACTTGCTCA
CATTCCGTGGGTAAAGCGTATAAATATTTCGGCTAAGACGGGACGTGCCCTTCAAAGACTAGAGCCGTACATGCTGGAAG
CGCTGGAAAGCTGGGATAAGCGTGTTACCACAGGTCAGCTAAACAACTGGTTGCGGGCGACTATTGCACAGAATCCGCCA
CCAATGAAGGGGGGCCGTGTTCCTCGCGTATTGTTCGCCACGCAAGCTTCAACTCAACCGCCTACGATTGTGCTATTTAC
CACTGGTTTCTTAGACGCTGGTTATCGTCGCTACCTTGAACGCAAGTTTAGGGAAAGCTTTGGTTTCGAGGGGTCCCCAG
TCAAGATTGCAGTTCGTGTGCGCGAACGTCGTTCAAAGAAGTGA

Upstream 100 bases:

>100_bases
CTAGTGACGCAACCGTTGTCGATACTTCTACGTTAACCCTTGATCAAGTCGTCGATACTTTGATGACTCTGATTGAAAAA
TCTGCTGAAAGGACCGCACG

Downstream 100 bases:

>100_bases
TAATTCTTTAAAGATTTATCGTTAGTCGCCCATTTGCTATGCAATATCTATGCAAATGGGCGACTTTTGCATTTAATTTC
CATATATTCCAAAATGAATT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSNAHNAPLGGNNSSDEDQETVFVYHTAHGEVDAQEAFVEEDVVVDGAGYASDGFDENDFDFDFEHDSEGNVVFDEADFG
EADFGEDYTDEDWEELERAFGVGSRAIESENLCTVAIVGRPNVGKSSLVNRFLGRREAVVEDFPGVTRDRISYLADWGGR
RFWVQDTGGWDPNVKGIHAVIARQAETAMATADVIVMVVDTKVGITETDSVMARKLQKSEVPVILVANKFDSDSQYADMA
EFYALGLGDPWPVSAQHGRGGADVLEQILAAFPETPRATSIVEGPRRVALVGKPNVGKSSLLNKMSGEDRSVVDNVSGTT
VDPVDSIVKLDKHLWKFIDTAGLRKKVKNAQGHEYYASLRTRGVIDAAEICIFMIDSSEPVSEQDQRVLAMILDAGKALV
LVFNKWDLMEEDRRWELEREIDLQLAHIPWVKRINISAKTGRALQRLEPYMLEALESWDKRVTTGQLNNWLRATIAQNPP
PMKGGRVPRVLFATQASTQPPTIVLFTTGFLDAGYRRYLERKFRESFGFEGSPVKIAVRVRERRSKK

Sequences:

>Translated_547_residues
MSNAHNAPLGGNNSSDEDQETVFVYHTAHGEVDAQEAFVEEDVVVDGAGYASDGFDENDFDFDFEHDSEGNVVFDEADFG
EADFGEDYTDEDWEELERAFGVGSRAIESENLCTVAIVGRPNVGKSSLVNRFLGRREAVVEDFPGVTRDRISYLADWGGR
RFWVQDTGGWDPNVKGIHAVIARQAETAMATADVIVMVVDTKVGITETDSVMARKLQKSEVPVILVANKFDSDSQYADMA
EFYALGLGDPWPVSAQHGRGGADVLEQILAAFPETPRATSIVEGPRRVALVGKPNVGKSSLLNKMSGEDRSVVDNVSGTT
VDPVDSIVKLDKHLWKFIDTAGLRKKVKNAQGHEYYASLRTRGVIDAAEICIFMIDSSEPVSEQDQRVLAMILDAGKALV
LVFNKWDLMEEDRRWELEREIDLQLAHIPWVKRINISAKTGRALQRLEPYMLEALESWDKRVTTGQLNNWLRATIAQNPP
PMKGGRVPRVLFATQASTQPPTIVLFTTGFLDAGYRRYLERKFRESFGFEGSPVKIAVRVRERRSKK
>Mature_546_residues
SNAHNAPLGGNNSSDEDQETVFVYHTAHGEVDAQEAFVEEDVVVDGAGYASDGFDENDFDFDFEHDSEGNVVFDEADFGE
ADFGEDYTDEDWEELERAFGVGSRAIESENLCTVAIVGRPNVGKSSLVNRFLGRREAVVEDFPGVTRDRISYLADWGGRR
FWVQDTGGWDPNVKGIHAVIARQAETAMATADVIVMVVDTKVGITETDSVMARKLQKSEVPVILVANKFDSDSQYADMAE
FYALGLGDPWPVSAQHGRGGADVLEQILAAFPETPRATSIVEGPRRVALVGKPNVGKSSLLNKMSGEDRSVVDNVSGTTV
DPVDSIVKLDKHLWKFIDTAGLRKKVKNAQGHEYYASLRTRGVIDAAEICIFMIDSSEPVSEQDQRVLAMILDAGKALVL
VFNKWDLMEEDRRWELEREIDLQLAHIPWVKRINISAKTGRALQRLEPYMLEALESWDKRVTTGQLNNWLRATIAQNPPP
MKGGRVPRVLFATQASTQPPTIVLFTTGFLDAGYRRYLERKFRESFGFEGSPVKIAVRVRERRSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=34.7252747252747, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1788919, Length=166, Percent_Identity=30.1204819277108, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=196, Percent_Identity=25, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 60884; Mature: 60753

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAHNAPLGGNNSSDEDQETVFVYHTAHGEVDAQEAFVEEDVVVDGAGYASDGFDENDF
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCC
DFDFEHDSEGNVVFDEADFGEADFGEDYTDEDWEELERAFGVGSRAIESENLCTVAIVGR
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCEEEEEECC
PNVGKSSLVNRFLGRREAVVEDFPGVTRDRISYLADWGGRRFWVQDTGGWDPNVKGIHAV
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHH
IARQAETAMATADVIVMVVDTKVGITETDSVMARKLQKSEVPVILVANKFDSDSQYADMA
HHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
EFYALGLGDPWPVSAQHGRGGADVLEQILAAFPETPRATSIVEGPRRVALVGKPNVGKSS
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCCHHH
LLNKMSGEDRSVVDNVSGTTVDPVDSIVKLDKHLWKFIDTAGLRKKVKNAQGHEYYASLR
HHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TRGVIDAAEICIFMIDSSEPVSEQDQRVLAMILDAGKALVLVFNKWDLMEEDRRWELERE
HCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
IDLQLAHIPWVKRINISAKTGRALQRLEPYMLEALESWDKRVTTGQLNNWLRATIAQNPP
CCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PMKGGRVPRVLFATQASTQPPTIVLFTTGFLDAGYRRYLERKFRESFGFEGSPVKIAVRV
CCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
RERRSKK
HHHCCCC
>Mature Secondary Structure 
SNAHNAPLGGNNSSDEDQETVFVYHTAHGEVDAQEAFVEEDVVVDGAGYASDGFDENDF
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCEEEECCCCCCCCCCCCCC
DFDFEHDSEGNVVFDEADFGEADFGEDYTDEDWEELERAFGVGSRAIESENLCTVAIVGR
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCCCCEEEEEECC
PNVGKSSLVNRFLGRREAVVEDFPGVTRDRISYLADWGGRRFWVQDTGGWDPNVKGIHAV
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHH
IARQAETAMATADVIVMVVDTKVGITETDSVMARKLQKSEVPVILVANKFDSDSQYADMA
HHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHH
EFYALGLGDPWPVSAQHGRGGADVLEQILAAFPETPRATSIVEGPRRVALVGKPNVGKSS
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEECCCCCHHH
LLNKMSGEDRSVVDNVSGTTVDPVDSIVKLDKHLWKFIDTAGLRKKVKNAQGHEYYASLR
HHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
TRGVIDAAEICIFMIDSSEPVSEQDQRVLAMILDAGKALVLVFNKWDLMEEDRRWELERE
HCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCC
IDLQLAHIPWVKRINISAKTGRALQRLEPYMLEALESWDKRVTTGQLNNWLRATIAQNPP
CCEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCC
PMKGGRVPRVLFATQASTQPPTIVLFTTGFLDAGYRRYLERKFRESFGFEGSPVKIAVRV
CCCCCCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
RERRSKK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]