Click here to switch to the map view.

The map label for this gene is recG [H]

Identifier: 38233726

GI number: 38233726

Start: 1121804

End: 1123918

Strand: Direct

Name: recG [H]

Synonym: DIP1136

Alternate gene names: 38233726

Gene position: 1121804-1123918 (Clockwise)

Preceding gene: 38233725

Following gene: 38233727

Centisome position: 45.08

GC content: 57.02

Gene sequence:

>2115_bases
ATGCTCGGCTGGCACGACCAACGACCACTGGCACAACTCTTGCCAGCCAAAGAAGCAAAAGCGTTCTCTCGACACTTCAG
CTTCACTACCGTCGAAGACCTACTCCAACACTTTCCCCGCGGATACGCAGCCCACGGCACTGGACTCGCAGCCGAAGCCG
CAGAAGAAGGTGACATCATTACCTGCGTGGGAACCATTGTCGACACCCACGAGCACCCCGATCGCAACGGATACAGCATC
TACTCCGTCGTAATCTCCGACGGCTTTACCCGCAGCACCGCCACATTTTTTCGTGCCACATGGATCAAAAAAGTCCTCAC
CCACGGAGCACAAGGAATCTTCACCGGAAAACTCAAATTCTTCCGCAACACCCCACAACTCCAGCACCCCGACTTCTTCC
TCTTCCCAGAAAAAGGCAAAAAAGCAACCGGAACCGGCGGAATGCAAGCACTATCAACCACCGGCGAACTCGACGACATC
ACCGACATCCTCGTCGCCATGAGCTACCTGCCGGTCTACCCAGCCAAAAAAGCAATCCCCACCTGGCGCATCCTCGGCGC
CGTCCACAACATCCTTACCCACACCCCACACATCGCAGATCCACTCCACGAATTCGCACCCCACGACCTCCCCAGCTTCG
ACCAAGCACTACGCGGCATCCACGAACCCGACGAACACGGCCCCCAGCACTACATCACACGCATCAAATACGACGAAGCC
CTCACCCTCGCGCTCGTCATGGCACTACGACGCGCCGACACACAACGTCGACACGCATACCCCATACCCCCAACCAACGA
TGGCCTACGCGCGCACATGCTCAGCCACCTCCCATTCGAGCTCACCGAAGGCCAACACAACGTCCTCACTGAAATCAGCG
CAGACCTCGCACAACCCACCCCCATGTCCCGCCTCCTACAAGGCGAAGTAGGATCCGGAAAAACCATCGTCTCACTCCTC
GCCATGCTCCAAGTCATCGACGACGGCAAACAATGCGTACTACTCGCACCCACCGAAGTACTCGCGGCACAACACGCAAC
ATCCATCACCCAACAACTCACCAACGCCGGCATCAACATCAACGTCACCCTCCTCACCGGATCACTACCCACCGAACAAC
GCAGAAAAGCCCTCTTCAACATCATCTCCGGCGACGCAAACCTCATCATCGGAACCCACGCCCTCATCCAAGAAGGAATC
GAATTCTTCGACCTCGCACTCTGCGTCATCGACGAACAACACCGATTCGGAGTCGAACAACGCGACCACCTCCGCAACCA
AGGACGCGACACCAACACCCCACACGTCCTCGTCATGACAGCAACCCCCATCCCACGATCCATCGCCATGACCGCCTTCG
GTGACCTCAGCGTCTCAACCCTCAAACAACTCCCCGGCGGACGACGCCCCATACACAGCTACGTCATCGACCACCAACAC
ACCACATGGACCACACGCATGTGGGAACGCATACGCGAAGAAATCGACAAAGGCCACCAAATCTACATAGTCTGCCCCAA
AATCAAAGATTCTGGAGGAGTAGAAGAAACCACCCATCAACTCACCACAGGCATACTCGCCAACTACCGCATCGCCATGC
TCCACGGCGCCATGCACCCCGAAGACAAAGACACCACCATGAAAGCCTTCGCCGCCGGAACTATCGACGTCCTCGTAGCC
ACCACCGTCATCGAAGTCGGAATCGACGTCCCCAACGCCACCGTCATGCTCATCCGCGAATCCGAAAACTTCGGCGTATC
ACAACTCCACCAACTCCGCGGCCGAGTCGGACGAGGCGGCAACGAATCCATCTGCTTCTTCCACACAACCGCACAACCAA
CAACTCCCGCCCACAACCGAGTCACAGCCGTCGCCGCAACCACAGACGGATTCGAACTCGCCGAAATCGACCTCACCTAC
CGACACGAAGGCAACATCCTCGGCACACAACAATCCGGGCACACCAACAGAATCATCAGCTTCATCCACGACAAAGACCT
CATCGAACGCGCCAACAACGACGCAACCCACATCGTTACACACAACCCCCAACTAGCACGCCATCTCGTCGCCGACATCG
ACGACACCACCCAAACCTACATTGACAAGTCATAA

Upstream 100 bases:

>100_bases
GACAATCACTCACTGACCGGGCCACACACCGATGTAGAAATCAACCAGTACGATGTAGATCGTCTCGGAGCTCTTATCGA
AATCGGGGTGGAATAACATC

Downstream 100 bases:

>100_bases
CCACCCCCATGCGATAAAGTAACAAACATGAAAATCTGCGCCCCATTCGCCGGAATAGTCCACTACAAAGTCTCCCTAGG
AGACACAGTCACCACCGGAC

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MLGWHDQRPLAQLLPAKEAKAFSRHFSFTTVEDLLQHFPRGYAAHGTGLAAEAAEEGDIITCVGTIVDTHEHPDRNGYSI
YSVVISDGFTRSTATFFRATWIKKVLTHGAQGIFTGKLKFFRNTPQLQHPDFFLFPEKGKKATGTGGMQALSTTGELDDI
TDILVAMSYLPVYPAKKAIPTWRILGAVHNILTHTPHIADPLHEFAPHDLPSFDQALRGIHEPDEHGPQHYITRIKYDEA
LTLALVMALRRADTQRRHAYPIPPTNDGLRAHMLSHLPFELTEGQHNVLTEISADLAQPTPMSRLLQGEVGSGKTIVSLL
AMLQVIDDGKQCVLLAPTEVLAAQHATSITQQLTNAGININVTLLTGSLPTEQRRKALFNIISGDANLIIGTHALIQEGI
EFFDLALCVIDEQHRFGVEQRDHLRNQGRDTNTPHVLVMTATPIPRSIAMTAFGDLSVSTLKQLPGGRRPIHSYVIDHQH
TTWTTRMWERIREEIDKGHQIYIVCPKIKDSGGVEETTHQLTTGILANYRIAMLHGAMHPEDKDTTMKAFAAGTIDVLVA
TTVIEVGIDVPNATVMLIRESENFGVSQLHQLRGRVGRGGNESICFFHTTAQPTTPAHNRVTAVAATTDGFELAEIDLTY
RHEGNILGTQQSGHTNRIISFIHDKDLIERANNDATHIVTHNPQLARHLVADIDDTTQTYIDKS

Sequences:

>Translated_704_residues
MLGWHDQRPLAQLLPAKEAKAFSRHFSFTTVEDLLQHFPRGYAAHGTGLAAEAAEEGDIITCVGTIVDTHEHPDRNGYSI
YSVVISDGFTRSTATFFRATWIKKVLTHGAQGIFTGKLKFFRNTPQLQHPDFFLFPEKGKKATGTGGMQALSTTGELDDI
TDILVAMSYLPVYPAKKAIPTWRILGAVHNILTHTPHIADPLHEFAPHDLPSFDQALRGIHEPDEHGPQHYITRIKYDEA
LTLALVMALRRADTQRRHAYPIPPTNDGLRAHMLSHLPFELTEGQHNVLTEISADLAQPTPMSRLLQGEVGSGKTIVSLL
AMLQVIDDGKQCVLLAPTEVLAAQHATSITQQLTNAGININVTLLTGSLPTEQRRKALFNIISGDANLIIGTHALIQEGI
EFFDLALCVIDEQHRFGVEQRDHLRNQGRDTNTPHVLVMTATPIPRSIAMTAFGDLSVSTLKQLPGGRRPIHSYVIDHQH
TTWTTRMWERIREEIDKGHQIYIVCPKIKDSGGVEETTHQLTTGILANYRIAMLHGAMHPEDKDTTMKAFAAGTIDVLVA
TTVIEVGIDVPNATVMLIRESENFGVSQLHQLRGRVGRGGNESICFFHTTAQPTTPAHNRVTAVAATTDGFELAEIDLTY
RHEGNILGTQQSGHTNRIISFIHDKDLIERANNDATHIVTHNPQLARHLVADIDDTTQTYIDKS
>Mature_704_residues
MLGWHDQRPLAQLLPAKEAKAFSRHFSFTTVEDLLQHFPRGYAAHGTGLAAEAAEEGDIITCVGTIVDTHEHPDRNGYSI
YSVVISDGFTRSTATFFRATWIKKVLTHGAQGIFTGKLKFFRNTPQLQHPDFFLFPEKGKKATGTGGMQALSTTGELDDI
TDILVAMSYLPVYPAKKAIPTWRILGAVHNILTHTPHIADPLHEFAPHDLPSFDQALRGIHEPDEHGPQHYITRIKYDEA
LTLALVMALRRADTQRRHAYPIPPTNDGLRAHMLSHLPFELTEGQHNVLTEISADLAQPTPMSRLLQGEVGSGKTIVSLL
AMLQVIDDGKQCVLLAPTEVLAAQHATSITQQLTNAGININVTLLTGSLPTEQRRKALFNIISGDANLIIGTHALIQEGI
EFFDLALCVIDEQHRFGVEQRDHLRNQGRDTNTPHVLVMTATPIPRSIAMTAFGDLSVSTLKQLPGGRRPIHSYVIDHQH
TTWTTRMWERIREEIDKGHQIYIVCPKIKDSGGVEETTHQLTTGILANYRIAMLHGAMHPEDKDTTMKAFAAGTIDVLVA
TTVIEVGIDVPNATVMLIRESENFGVSQLHQLRGRVGRGGNESICFFHTTAQPTTPAHNRVTAVAATTDGFELAEIDLTY
RHEGNILGTQQSGHTNRIISFIHDKDLIERANNDATHIVTHNPQLARHLVADIDDTTQTYIDKS

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=700, Percent_Identity=35.2857142857143, Blast_Score=333, Evalue=2e-92,
Organism=Escherichia coli, GI1787357, Length=401, Percent_Identity=33.6658354114713, Blast_Score=220, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77861; Mature: 77861

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00435 PEROXIDASE_1 ; PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGWHDQRPLAQLLPAKEAKAFSRHFSFTTVEDLLQHFPRGYAAHGTGLAAEAAEEGDII
CCCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEE
TCVGTIVDTHEHPDRNGYSIYSVVISDGFTRSTATFFRATWIKKVLTHGAQGIFTGKLKF
EEEEHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHE
FRNTPQLQHPDFFLFPEKGKKATGTGGMQALSTTGELDDITDILVAMSYLPVYPAKKAIP
ECCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
TWRILGAVHNILTHTPHIADPLHEFAPHDLPSFDQALRGIHEPDEHGPQHYITRIKYDEA
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHEEEECHHH
LTLALVMALRRADTQRRHAYPIPPTNDGLRAHMLSHLPFELTEGQHNVLTEISADLAQPT
HHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCC
PMSRLLQGEVGSGKTIVSLLAMLQVIDDGKQCVLLAPTEVLAAQHATSITQQLTNAGINI
CHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEE
NVTLLTGSLPTEQRRKALFNIISGDANLIIGTHALIQEGIEFFDLALCVIDEQHRFGVEQ
EEEEEECCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHEECCHHHCCCCH
RDHLRNQGRDTNTPHVLVMTATPIPRSIAMTAFGDLSVSTLKQLPGGRRPIHSYVIDHQH
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHCCCCCCCHHHHHCCCCC
TTWTTRMWERIREEIDKGHQIYIVCPKIKDSGGVEETTHQLTTGILANYRIAMLHGAMHP
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
EDKDTTMKAFAAGTIDVLVATTVIEVGIDVPNATVMLIRESENFGVSQLHQLRGRVGRGG
CCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCC
NESICFFHTTAQPTTPAHNRVTAVAATTDGFELAEIDLTYRHEGNILGTQQSGHTNRIIS
CCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCEEECCCCCCHHHHHH
FIHDKDLIERANNDATHIVTHNPQLARHLVADIDDTTQTYIDKS
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure
MLGWHDQRPLAQLLPAKEAKAFSRHFSFTTVEDLLQHFPRGYAAHGTGLAAEAAEEGDII
CCCCCCCCCHHHHCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEE
TCVGTIVDTHEHPDRNGYSIYSVVISDGFTRSTATFFRATWIKKVLTHGAQGIFTGKLKF
EEEEHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHE
FRNTPQLQHPDFFLFPEKGKKATGTGGMQALSTTGELDDITDILVAMSYLPVYPAKKAIP
ECCCCCCCCCCEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
TWRILGAVHNILTHTPHIADPLHEFAPHDLPSFDQALRGIHEPDEHGPQHYITRIKYDEA
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCHHHHEEEECHHH
LTLALVMALRRADTQRRHAYPIPPTNDGLRAHMLSHLPFELTEGQHNVLTEISADLAQPT
HHHHHHHHHHHHCHHHCCCCCCCCCCCCHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCC
PMSRLLQGEVGSGKTIVSLLAMLQVIDDGKQCVLLAPTEVLAAQHATSITQQLTNAGINI
CHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEE
NVTLLTGSLPTEQRRKALFNIISGDANLIIGTHALIQEGIEFFDLALCVIDEQHRFGVEQ
EEEEEECCCCHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHEECCHHHCCCCH
RDHLRNQGRDTNTPHVLVMTATPIPRSIAMTAFGDLSVSTLKQLPGGRRPIHSYVIDHQH
HHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHCCCCCCCHHHHHCCCCC
TTWTTRMWERIREEIDKGHQIYIVCPKIKDSGGVEETTHQLTTGILANYRIAMLHGAMHP
CHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
EDKDTTMKAFAAGTIDVLVATTVIEVGIDVPNATVMLIRESENFGVSQLHQLRGRVGRGG
CCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCC
NESICFFHTTAQPTTPAHNRVTAVAATTDGFELAEIDLTYRHEGNILGTQQSGHTNRIIS
CCCEEEEEECCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCEEECCCCCCHHHHHH
FIHDKDLIERANNDATHIVTHNPQLARHLVADIDDTTQTYIDKS
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]