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The map label for this gene is ppc

Identifier: 38233712

GI number: 38233712

Start: 1106381

End: 1109089

Strand: Direct

Name: ppc

Synonym: DIP1122

Alternate gene names: 38233712

Gene position: 1106381-1109089 (Clockwise)

Preceding gene: 38233711

Following gene: 38233715

Centisome position: 44.46

GC content: 53.16

Gene sequence:

>2709_bases
GTGACTGCTGCCATTTCTGATCGTGTCCGTGAAGATATTCGATTGCTGGGACGCGTACTAGGACGAGTTATTGCGCAGCA
AGAGGGCGAAGAAGTCTATGAGCTGGTAGAAGCTACTAGACGCATGGCGTTTGATGTTTCTCATGGTGACGCTGATCCTG
AAGATTTAATGGTGATTTTTAGGGATCTTGATATCACTAAGACCAACCTTGTTGCTCGTGCTTTTAGTTATTTTGCGCTG
CTGGCTAATTTGGTTGAGGATCTTGATGATGAATCCGTAGAGGCGGATGTTTCATTGCGTAAAACTTTTGCCAAGCTTAA
GCGGGAGGGGGTGTCTGCAGCTGATGCTGCGAGTGTGATTCGTAGTGCTGAGGTTGCACCGGTGCTTACGGCGCATCCTA
CGGAGACGCGTCGTCGTACGGTGTTTGATACTCAGACTCGGATCAAGCAGTTGCTCAAAGACGCCCATCATGGTGGGGAT
ATGCAGGTCATTGAGCAGGAAATGTATCTGCGGATGACGCTCTTGTGGCAAACCGCGCTGATTCGTATTGCGCGTCCAAC
GCTGGAGGATGAGATCGATGTGGGGTTGCGCTATTACAAGAAGTCACTCTTGGAGCAGGTTCCTGCGTTGAATCGTTCGA
TCCGTCATTCTATGAGGGAGACGTTTGGTCTGCAGCTGCCAGATATTGCGGTGATGCGTCCTGGCTCGTGGATTGGTGGC
GATCACGATGGTAATCCGTATGTTAATGCTCGTACCTTGACGTACGCGACGCGTCAGGCCGCCAAGACAGTGGCGCGTTA
TTACGTGGAGCAGTTGGGTGAACTGGAACGCGAGCTGTCGCTGTCTGATCGTTATTCTTCGTGCTCCAAGGAGCTGCTTG
CGTTGGCCGAGGCTTCGGGTAACAACTGGGAATCGCGTGTTGATGAGCCGTATCGTCGTGCAGTCTATGGGATGCGCGCC
CGTATGAAGTCCAATGTGGACGCTTTGGAGCGTCCGGAGAAAACAGCGGGGAAGAAGTCGTCGAAACGCACGCCTTATGC
AACTCCTGAGGAGTTCTTGCGCGATCTTGATGTGATTGATCGATCATTGCGTGCGCACAATGATGATGTGATCGCTGATG
ATCGGCTAGCGCGTATCCGCTCGGCTGTAACCACTTTTGGGTTCCATTTGTACACTCTCGATATCCGTCAGAATTCTGAG
TCTTTTGAGGCTGTGATCGAGGAGGTATTCGCGGCAGCGCGTCGTGTACCCGGCGGTAAGCGTTATTCGGAGCTTGCTGA
GGCAGAAAAGGTTGAGCTGCTTATCCAGGAGCTGCAAACTCCGCGTCCGCTGTTGTTCCCCGGCGCGCTTGAGGTCGAGG
ATGCGTTTAGCGCTGATACCACTAAGGAATTGGGGATTTTCTTAGCGGCGGCTCAGGCGGTGCGGGATTTCGGATCGCGG
TCAATTGCGCATTGCATTATTTCGATGACGGCTACGGTGTCCGACATTTTGGAGCCTATGGTGCTGTTGAAGGAAGTCGG
ATTGCGTGATGTTGATGTGGTTCCGCTTTTTGAGACTATCGACGATCTTCGCTGCGGTGCTGCTATTTTGCGCGAGCTGT
GGTCGCATCCGTTTTATCGTGAGCATCTTCGTGCCCGTGGGGATATCCAAGAGGTGATGTTGGGGTATTCCGATTCCAAC
AAGGACGGCGGGTATCTGCAAGCTAACTGGGCGTTGTATGATGCTGAGCTGGGCTTGGTGGAGTTGTGCCGTGAGCACAA
TATTGAGTTGCGTTTGGCTCATGGCCGTGGTGGCGCTGTGGGCCGTGGTGGTGGACCTACTTACGATGCGATTTTGGCGC
AGCCGAAGGGTGCGGTGTCGGGTTCTGTTCGTATTACGGAGCAGGGTGAGGTGATTTCTGCGAAGTATGGTGCGCCTGAG
ACGGCGCGCCGTCACTTGGAGGCGTTTGTTTCGGGGGCGTTGGAGGCGTCGCTTCTCGATACTGAGCCGATTGCGGATCC
GGATCGTGCGTATGCGATTATGCGTGATCTTGCTGGCTTTAGTGGTCAGAGGTATCAGGAGTTGGTGGGAGATCCTGGGT
TTATTGAGTACTTCACGCAGTCGACTCCATTGCATGAGATTGGTGAGCTTAATCTGGGGTCGCGTCCTGCTGCGCGTAAG
CAAACGACAGCTATTTCAGATCTTCGTGCTATTCCGTGGGTGTTGTCGTGGTCGCAGTCGCGGACCAATATTCCTGGTTG
GTTTGGTGTTGGTAGCGCGGTGAGCCGTTTTGTATCGGCGGTGCCGGAGAAGGACCGAGAGTCACGGTGGCAGGAGCTGC
GTGATTTGTATGCAACGTGGCCATTTTTCCGCTCGGTGATGTCAAATATGGCTCAGGTTATGGCCAAGGCAGAGATCTCG
CTGGCAAGGTTGTATGCCGATTTGGTGGATGATCCCGAGGTTGCTGACCGGATTTATGCGTTGATTGCAGAAGAATTTGA
ACTTACGCGTCGTGCATATTTGGCTATTACTGGTAATGAGGCACTGGTGTCGGAAAACCAGCGCCAAGCCCGTTCACTTA
AGCGGCGTTACCCGTATTTGCTACCGCTTAACGCCATTCAGCTGGAGTTGCTGCGGCGTTATCGTGGTGGCGATGATCAA
TTCTTGGTGTCTAAGACTATTCAGGTCACCATGAATGGTTTGGCCACTGCGTTGCGTAATGCGGGGTAG

Upstream 100 bases:

>100_bases
ATGGGGGATATGCGCACCAATATGCCGAGCAGGCTTGGTGATCTGCGCTACATTGATGGGCACACTTTGTATCCATCACT
TTTGTAGGAAGGCTGAGCTC

Downstream 100 bases:

>100_bases
GAAGGGGATCTATACGATCTTTTTCACCACTGCTGGTTTGAGGATCATCTGGCCGAAGCCGTCGATTTTGCATTCGATGT
TGTGATCCTCAGGGCCGGTA

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 902; Mature: 901

Protein sequence:

>902_residues
MTAAISDRVREDIRLLGRVLGRVIAQQEGEEVYELVEATRRMAFDVSHGDADPEDLMVIFRDLDITKTNLVARAFSYFAL
LANLVEDLDDESVEADVSLRKTFAKLKREGVSAADAASVIRSAEVAPVLTAHPTETRRRTVFDTQTRIKQLLKDAHHGGD
MQVIEQEMYLRMTLLWQTALIRIARPTLEDEIDVGLRYYKKSLLEQVPALNRSIRHSMRETFGLQLPDIAVMRPGSWIGG
DHDGNPYVNARTLTYATRQAAKTVARYYVEQLGELERELSLSDRYSSCSKELLALAEASGNNWESRVDEPYRRAVYGMRA
RMKSNVDALERPEKTAGKKSSKRTPYATPEEFLRDLDVIDRSLRAHNDDVIADDRLARIRSAVTTFGFHLYTLDIRQNSE
SFEAVIEEVFAAARRVPGGKRYSELAEAEKVELLIQELQTPRPLLFPGALEVEDAFSADTTKELGIFLAAAQAVRDFGSR
SIAHCIISMTATVSDILEPMVLLKEVGLRDVDVVPLFETIDDLRCGAAILRELWSHPFYREHLRARGDIQEVMLGYSDSN
KDGGYLQANWALYDAELGLVELCREHNIELRLAHGRGGAVGRGGGPTYDAILAQPKGAVSGSVRITEQGEVISAKYGAPE
TARRHLEAFVSGALEASLLDTEPIADPDRAYAIMRDLAGFSGQRYQELVGDPGFIEYFTQSTPLHEIGELNLGSRPAARK
QTTAISDLRAIPWVLSWSQSRTNIPGWFGVGSAVSRFVSAVPEKDRESRWQELRDLYATWPFFRSVMSNMAQVMAKAEIS
LARLYADLVDDPEVADRIYALIAEEFELTRRAYLAITGNEALVSENQRQARSLKRRYPYLLPLNAIQLELLRRYRGGDDQ
FLVSKTIQVTMNGLATALRNAG

Sequences:

>Translated_902_residues
MTAAISDRVREDIRLLGRVLGRVIAQQEGEEVYELVEATRRMAFDVSHGDADPEDLMVIFRDLDITKTNLVARAFSYFAL
LANLVEDLDDESVEADVSLRKTFAKLKREGVSAADAASVIRSAEVAPVLTAHPTETRRRTVFDTQTRIKQLLKDAHHGGD
MQVIEQEMYLRMTLLWQTALIRIARPTLEDEIDVGLRYYKKSLLEQVPALNRSIRHSMRETFGLQLPDIAVMRPGSWIGG
DHDGNPYVNARTLTYATRQAAKTVARYYVEQLGELERELSLSDRYSSCSKELLALAEASGNNWESRVDEPYRRAVYGMRA
RMKSNVDALERPEKTAGKKSSKRTPYATPEEFLRDLDVIDRSLRAHNDDVIADDRLARIRSAVTTFGFHLYTLDIRQNSE
SFEAVIEEVFAAARRVPGGKRYSELAEAEKVELLIQELQTPRPLLFPGALEVEDAFSADTTKELGIFLAAAQAVRDFGSR
SIAHCIISMTATVSDILEPMVLLKEVGLRDVDVVPLFETIDDLRCGAAILRELWSHPFYREHLRARGDIQEVMLGYSDSN
KDGGYLQANWALYDAELGLVELCREHNIELRLAHGRGGAVGRGGGPTYDAILAQPKGAVSGSVRITEQGEVISAKYGAPE
TARRHLEAFVSGALEASLLDTEPIADPDRAYAIMRDLAGFSGQRYQELVGDPGFIEYFTQSTPLHEIGELNLGSRPAARK
QTTAISDLRAIPWVLSWSQSRTNIPGWFGVGSAVSRFVSAVPEKDRESRWQELRDLYATWPFFRSVMSNMAQVMAKAEIS
LARLYADLVDDPEVADRIYALIAEEFELTRRAYLAITGNEALVSENQRQARSLKRRYPYLLPLNAIQLELLRRYRGGDDQ
FLVSKTIQVTMNGLATALRNAG
>Mature_901_residues
TAAISDRVREDIRLLGRVLGRVIAQQEGEEVYELVEATRRMAFDVSHGDADPEDLMVIFRDLDITKTNLVARAFSYFALL
ANLVEDLDDESVEADVSLRKTFAKLKREGVSAADAASVIRSAEVAPVLTAHPTETRRRTVFDTQTRIKQLLKDAHHGGDM
QVIEQEMYLRMTLLWQTALIRIARPTLEDEIDVGLRYYKKSLLEQVPALNRSIRHSMRETFGLQLPDIAVMRPGSWIGGD
HDGNPYVNARTLTYATRQAAKTVARYYVEQLGELERELSLSDRYSSCSKELLALAEASGNNWESRVDEPYRRAVYGMRAR
MKSNVDALERPEKTAGKKSSKRTPYATPEEFLRDLDVIDRSLRAHNDDVIADDRLARIRSAVTTFGFHLYTLDIRQNSES
FEAVIEEVFAAARRVPGGKRYSELAEAEKVELLIQELQTPRPLLFPGALEVEDAFSADTTKELGIFLAAAQAVRDFGSRS
IAHCIISMTATVSDILEPMVLLKEVGLRDVDVVPLFETIDDLRCGAAILRELWSHPFYREHLRARGDIQEVMLGYSDSNK
DGGYLQANWALYDAELGLVELCREHNIELRLAHGRGGAVGRGGGPTYDAILAQPKGAVSGSVRITEQGEVISAKYGAPET
ARRHLEAFVSGALEASLLDTEPIADPDRAYAIMRDLAGFSGQRYQELVGDPGFIEYFTQSTPLHEIGELNLGSRPAARKQ
TTAISDLRAIPWVLSWSQSRTNIPGWFGVGSAVSRFVSAVPEKDRESRWQELRDLYATWPFFRSVMSNMAQVMAKAEISL
ARLYADLVDDPEVADRIYALIAEEFELTRRAYLAITGNEALVSENQRQARSLKRRYPYLLPLNAIQLELLRRYRGGDDQF
LVSKTIQVTMNGLATALRNAG

Specific function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG2352

COG function: function code C; Phosphoenolpyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 1 family

Homologues:

Organism=Escherichia coli, GI1790393, Length=919, Percent_Identity=33.5146898803047, Blast_Score=396, Evalue=1e-111,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CAPP_CORDI (P61448)

Other databases:

- EMBL:   BX248357
- RefSeq:   NP_939479.1
- ProteinModelPortal:   P61448
- SMR:   P61448
- GeneID:   2649924
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1122
- NMPDR:   fig|257309.1.peg.1070
- HOGENOM:   HBG351035
- OMA:   AIPWVFG
- PhylomeDB:   P61448
- ProtClustDB:   PRK00009
- BioCyc:   CDIP257309:DIP1122-MONOMER
- BRENDA:   4.1.1.31
- HAMAP:   MF_00595
- InterPro:   IPR021135
- InterPro:   IPR018129
- InterPro:   IPR022805
- InterPro:   IPR015813
- PRINTS:   PR00150

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 101059; Mature: 100928

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00781 PEPCASE_1; PS00393 PEPCASE_2

Important sites: ACT_SITE 132-132 ACT_SITE 561-561

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAISDRVREDIRLLGRVLGRVIAQQEGEEVYELVEATRRMAFDVSHGDADPEDLMVIF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCHHHHEEHH
RDLDITKTNLVARAFSYFALLANLVEDLDDESVEADVSLRKTFAKLKREGVSAADAASVI
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RSAEVAPVLTAHPTETRRRTVFDTQTRIKQLLKDAHHGGDMQVIEQEMYLRMTLLWQTAL
HHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IRIARPTLEDEIDVGLRYYKKSLLEQVPALNRSIRHSMRETFGLQLPDIAVMRPGSWIGG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
DHDGNPYVNARTLTYATRQAAKTVARYYVEQLGELERELSLSDRYSSCSKELLALAEASG
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNWESRVDEPYRRAVYGMRARMKSNVDALERPEKTAGKKSSKRTPYATPEEFLRDLDVID
CCCHHHCCHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHH
RSLRAHNDDVIADDRLARIRSAVTTFGFHLYTLDIRQNSESFEAVIEEVFAAARRVPGGK
HHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
RYSELAEAEKVELLIQELQTPRPLLFPGALEVEDAFSADTTKELGIFLAAAQAVRDFGSR
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCH
SIAHCIISMTATVSDILEPMVLLKEVGLRDVDVVPLFETIDDLRCGAAILRELWSHPFYR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EHLRARGDIQEVMLGYSDSNKDGGYLQANWALYDAELGLVELCREHNIELRLAHGRGGAV
HHHHHCCCHHHHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCEEEEECCCCCCC
GRGGGPTYDAILAQPKGAVSGSVRITEQGEVISAKYGAPETARRHLEAFVSGALEASLLD
CCCCCCCHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
TEPIADPDRAYAIMRDLAGFSGQRYQELVGDPGFIEYFTQSTPLHEIGELNLGSRPAARK
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCCCHHHHCCCCCCCCCCCHH
QTTAISDLRAIPWVLSWSQSRTNIPGWFGVGSAVSRFVSAVPEKDRESRWQELRDLYATW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
PFFRSVMSNMAQVMAKAEISLARLYADLVDDPEVADRIYALIAEEFELTRRAYLAITGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCH
ALVSENQRQARSLKRRYPYLLPLNAIQLELLRRYRGGDDQFLVSKTIQVTMNGLATALRN
HHHCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
AG
CC
>Mature Secondary Structure 
TAAISDRVREDIRLLGRVLGRVIAQQEGEEVYELVEATRRMAFDVSHGDADPEDLMVIF
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECCCCCCCHHHHEEHH
RDLDITKTNLVARAFSYFALLANLVEDLDDESVEADVSLRKTFAKLKREGVSAADAASVI
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RSAEVAPVLTAHPTETRRRTVFDTQTRIKQLLKDAHHGGDMQVIEQEMYLRMTLLWQTAL
HHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
IRIARPTLEDEIDVGLRYYKKSLLEQVPALNRSIRHSMRETFGLQLPDIAVMRPGSWIGG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCC
DHDGNPYVNARTLTYATRQAAKTVARYYVEQLGELERELSLSDRYSSCSKELLALAEASG
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NNWESRVDEPYRRAVYGMRARMKSNVDALERPEKTAGKKSSKRTPYATPEEFLRDLDVID
CCCHHHCCHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHH
RSLRAHNDDVIADDRLARIRSAVTTFGFHLYTLDIRQNSESFEAVIEEVFAAARRVPGGK
HHHHCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
RYSELAEAEKVELLIQELQTPRPLLFPGALEVEDAFSADTTKELGIFLAAAQAVRDFGSR
HHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCH
SIAHCIISMTATVSDILEPMVLLKEVGLRDVDVVPLFETIDDLRCGAAILRELWSHPFYR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
EHLRARGDIQEVMLGYSDSNKDGGYLQANWALYDAELGLVELCREHNIELRLAHGRGGAV
HHHHHCCCHHHHHHCCCCCCCCCCEEEEEEEEEECCCCHHHHHHHCCCEEEEECCCCCCC
GRGGGPTYDAILAQPKGAVSGSVRITEQGEVISAKYGAPETARRHLEAFVSGALEASLLD
CCCCCCCHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCC
TEPIADPDRAYAIMRDLAGFSGQRYQELVGDPGFIEYFTQSTPLHEIGELNLGSRPAARK
CCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCCCHHHHCCCCCCCCCCCHH
QTTAISDLRAIPWVLSWSQSRTNIPGWFGVGSAVSRFVSAVPEKDRESRWQELRDLYATW
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
PFFRSVMSNMAQVMAKAEISLARLYADLVDDPEVADRIYALIAEEFELTRRAYLAITGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCH
ALVSENQRQARSLKRRYPYLLPLNAIQLELLRRYRGGDDQFLVSKTIQVTMNGLATALRN
HHHCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910