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The map label for this gene is ycgM [C]

Identifier: 38233702

GI number: 38233702

Start: 1095311

End: 1096108

Strand: Direct

Name: ycgM [C]

Synonym: DIP1112

Alternate gene names: 38233702

Gene position: 1095311-1096108 (Clockwise)

Preceding gene: 38233701

Following gene: 38233703

Centisome position: 44.01

GC content: 49.62

Gene sequence:

>798_bases
ATGCGTTTTGGACGAATTGCCACACCCGATGGAATGTGTTTCTGCGTTGTTGAGGGCGATGATGCCCAAGCAATCTGCAA
AGAAATTGAAGGAACCCCGTTTACCGAGCCTAAATATACGGGACGACAGTGGAAGTTGGACGAGGTGCGCTTGCTCGCAC
CCATGCTGCCTTCCAAGATTGTTGCCATTGGCCGTAACTATGCTGACCATGTTAAAGAGGTCTTTCAAAAGAGCGCTGAA
CATCTGCCACCAACGCTGTTTTTAAAGCCACCAACGGCCGTCGTGGGGCCAGGTGCTGCTATTCGAATTCCCGAGTTTGC
TACCAAGGTGGAATTCGAAGGTGAGCTGGCCATGGTTATTGCTAAGCCTTGTAAGAATGTAAAGAAAGAAGACTGGAAGT
CTGTAGTCTTAGGCTTCACTATCATCAACGATGTGTCGTCTCGCGACTTGCAGTTTGCTGATGGGCAGTGGGCACGTGCA
AAGGGCATTGACACTTTCGCGCCACTAGGTCCGTGGATTGAGACGGATATTGATTCGATTGAAACCGACAATCTTCCCAT
CAAAGCACACCTGACACATGATGGCATCACGGAGACTAAGCAGGACTCTAATTCCAATCAGATGATTATGGATCTCGGTG
AGATCATCGAGTTTATTACTGCTTCGTTTACATTGCTGCCTGGCGACGTCATCTGTACTGGTTCCCCCGCAGGTACCGCG
GCGATGGTTCCTGGTGACTTCATTGAAATCGAAATCCCAGGCATTGGCCGACTAGGTAATCCGGTAGCTAAAGCCTAG

Upstream 100 bases:

>100_bases
GCTAAAAAGCTGGTAGACGAGCTTTAGTCAAGCCCTTATATCGTGGGTGATTGCGTGCAAAATTGCACCACCATCACAGG
CATTCGGTAGGATCGCCTCT

Downstream 100 bases:

>100_bases
GAGTAGCGGTACCCTATGGGGTATGTCAACTACTCATAACAGCCTCCCCGCATCCTCTGATAAACATCATGATGGGCATG
GGGAAGCTTCTTTGTATCAC

Product: FAA family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MRFGRIATPDGMCFCVVEGDDAQAICKEIEGTPFTEPKYTGRQWKLDEVRLLAPMLPSKIVAIGRNYADHVKEVFQKSAE
HLPPTLFLKPPTAVVGPGAAIRIPEFATKVEFEGELAMVIAKPCKNVKKEDWKSVVLGFTIINDVSSRDLQFADGQWARA
KGIDTFAPLGPWIETDIDSIETDNLPIKAHLTHDGITETKQDSNSNQMIMDLGEIIEFITASFTLLPGDVICTGSPAGTA
AMVPGDFIEIEIPGIGRLGNPVAKA

Sequences:

>Translated_265_residues
MRFGRIATPDGMCFCVVEGDDAQAICKEIEGTPFTEPKYTGRQWKLDEVRLLAPMLPSKIVAIGRNYADHVKEVFQKSAE
HLPPTLFLKPPTAVVGPGAAIRIPEFATKVEFEGELAMVIAKPCKNVKKEDWKSVVLGFTIINDVSSRDLQFADGQWARA
KGIDTFAPLGPWIETDIDSIETDNLPIKAHLTHDGITETKQDSNSNQMIMDLGEIIEFITASFTLLPGDVICTGSPAGTA
AMVPGDFIEIEIPGIGRLGNPVAKA
>Mature_265_residues
MRFGRIATPDGMCFCVVEGDDAQAICKEIEGTPFTEPKYTGRQWKLDEVRLLAPMLPSKIVAIGRNYADHVKEVFQKSAE
HLPPTLFLKPPTAVVGPGAAIRIPEFATKVEFEGELAMVIAKPCKNVKKEDWKSVVLGFTIINDVSSRDLQFADGQWARA
KGIDTFAPLGPWIETDIDSIETDNLPIKAHLTHDGITETKQDSNSNQMIMDLGEIIEFITASFTLLPGDVICTGSPAGTA
AMVPGDFIEIEIPGIGRLGNPVAKA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=226, Percent_Identity=36.283185840708, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI40786394, Length=226, Percent_Identity=37.1681415929204, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI215422413, Length=205, Percent_Identity=31.7073170731707, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=32.5, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI13654274, Length=209, Percent_Identity=32.0574162679426, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=30.3482587064677, Blast_Score=91, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=32.5, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324161, Length=228, Percent_Identity=29.8245614035088, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28572127, Length=269, Percent_Identity=31.5985130111524, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24663695, Length=226, Percent_Identity=31.858407079646, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28571789, Length=208, Percent_Identity=33.1730769230769, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 28822; Mature: 28822

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFGRIATPDGMCFCVVEGDDAQAICKEIEGTPFTEPKYTGRQWKLDEVRLLAPMLPSKI
CCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHCCHHH
VAIGRNYADHVKEVFQKSAEHLPPTLFLKPPTAVVGPGAAIRIPEFATKVEFEGELAMVI
HHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCEEECCCHHEEEEECCCEEEEE
AKPCKNVKKEDWKSVVLGFTIINDVSSRDLQFADGQWARAKGIDTFAPLGPWIETDIDSI
EHHHHCCCHHHHHHHHHHHHEECCCCCCCEEECCCCCHHHCCCCCCCCCCCCHHCCCCCC
ETDNLPIKAHLTHDGITETKQDSNSNQMIMDLGEIIEFITASFTLLPGDVICTGSPAGTA
CCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCE
AMVPGDFIEIEIPGIGRLGNPVAKA
EECCCCEEEEEECCCCCCCCHHCCC
>Mature Secondary Structure
MRFGRIATPDGMCFCVVEGDDAQAICKEIEGTPFTEPKYTGRQWKLDEVRLLAPMLPSKI
CCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCEECHHHHHHHHHHCCHHH
VAIGRNYADHVKEVFQKSAEHLPPTLFLKPPTAVVGPGAAIRIPEFATKVEFEGELAMVI
HHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCEEECCCHHEEEEECCCEEEEE
AKPCKNVKKEDWKSVVLGFTIINDVSSRDLQFADGQWARAKGIDTFAPLGPWIETDIDSI
EHHHHCCCHHHHHHHHHHHHEECCCCCCCEEECCCCCHHHCCCCCCCCCCCCHHCCCCCC
ETDNLPIKAHLTHDGITETKQDSNSNQMIMDLGEIIEFITASFTLLPGDVICTGSPAGTA
CCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCEEECCCCCCCE
AMVPGDFIEIEIPGIGRLGNPVAKA
EECCCCEEEEEECCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]