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The map label for this gene is atpH

Identifier: 38233643

GI number: 38233643

Start: 1029912

End: 1030733

Strand: Direct

Name: atpH

Synonym: DIP1049

Alternate gene names: 38233643

Gene position: 1029912-1030733 (Clockwise)

Preceding gene: 38233642

Following gene: 38233644

Centisome position: 41.38

GC content: 57.54

Gene sequence:

>822_bases
ATGCACGCAGCGAGCCGCGAAGCACTAGCACGCGTTACCTCTGACCTCGACAAGGCATTGTGGGAGGCCAAGGAAAACGC
TATCGCTACTGCAGCGCACACTGGCGCAGAGCTTTTCGACGTCGTCGAGGTTCTGGATGGCGACCGCGCACTGCGCGTTG
CTGTCGCAGATTCCGCGAAGTCTGCCGAAGATCGCGCTGGATTGGTTTCTGCTGTGTTCGCCGGAAAAGTCAGCCCTGCG
ACGCTAGAGGTTCTCGTTACCTCTGCACGCGAACTGTGGTCTAACCCTCGCGAATTCCGTGATGGTCTGGTCACGTTGGG
CCGCCGCGCACTTCTCCGTTCTGCTGAAGGTCAAGGACAATTGGGTCAGGTTGAAGACGAACTCTTCCGCCTCTCCCGCA
TTTTGGACAAGGAGCCAGAGTTGACTCTCTTGCTCGATGACCGCAGCACAGACGGTGCAAAGAAGCGTGAGCTGCTGGCG
AAGGTGCTGTACGGCAAAGTCACTGCTGTGACTGAAGCCCTTGCACTCCAGGTTATTGGGCGTCGTGAGTCCAATGCGAT
CGACGATATTGATGCGCTATCTAAGGAGGCTGCTGCATTGCAGGGCCACTCCGTAGCACACGTCGTAAGCGCAGGACGTC
TCAATGACGAACAAAACCAGGCACTGGCACAGAAGCTAGAGCGCATTTATGGTCGTGCGATGAGCATCCACTCTGAGGTT
GATCCCAGCCTCCTCGGTGGTTTGGTCATCCGAGTTGGCGACGAAGTTATCGATGGATCGACCTCGGGCAAGCTCGAGCG
TCTCCGCGCGAACCTCGCGTAA

Upstream 100 bases:

>100_bases
TGCTTGGAGACCAGCTCTCCGATGACGTCAAGCGTTCCGGCACGATCGATAAGTTCTTGGCTGAGCTCGACACCGTGTCT
CCCGCAGGAAAGTGAGCACC

Downstream 100 bases:

>100_bases
GCCAACGCGACAACACAAATAGAAATAATGCTGGAAGAAACTACCGAGAGCAGGAAGAACATGGCGGAGCTTACGATCTC
CTCCGATGAGATCCGTAGCG

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MHAASREALARVTSDLDKALWEAKENAIATAAHTGAELFDVVEVLDGDRALRVAVADSAKSAEDRAGLVSAVFAGKVSPA
TLEVLVTSARELWSNPREFRDGLVTLGRRALLRSAEGQGQLGQVEDELFRLSRILDKEPELTLLLDDRSTDGAKKRELLA
KVLYGKVTAVTEALALQVIGRRESNAIDDIDALSKEAAALQGHSVAHVVSAGRLNDEQNQALAQKLERIYGRAMSIHSEV
DPSLLGGLVIRVGDEVIDGSTSGKLERLRANLA

Sequences:

>Translated_273_residues
MHAASREALARVTSDLDKALWEAKENAIATAAHTGAELFDVVEVLDGDRALRVAVADSAKSAEDRAGLVSAVFAGKVSPA
TLEVLVTSARELWSNPREFRDGLVTLGRRALLRSAEGQGQLGQVEDELFRLSRILDKEPELTLLLDDRSTDGAKKRELLA
KVLYGKVTAVTEALALQVIGRRESNAIDDIDALSKEAAALQGHSVAHVVSAGRLNDEQNQALAQKLERIYGRAMSIHSEV
DPSLLGGLVIRVGDEVIDGSTSGKLERLRANLA
>Mature_273_residues
MHAASREALARVTSDLDKALWEAKENAIATAAHTGAELFDVVEVLDGDRALRVAVADSAKSAEDRAGLVSAVFAGKVSPA
TLEVLVTSARELWSNPREFRDGLVTLGRRALLRSAEGQGQLGQVEDELFRLSRILDKEPELTLLLDDRSTDGAKKRELLA
KVLYGKVTAVTEALALQVIGRRESNAIDDIDALSKEAAALQGHSVAHVVSAGRLNDEQNQALAQKLERIYGRAMSIHSEV
DPSLLGGLVIRVGDEVIDGSTSGKLERLRANLA

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_CORDI (Q6NHT2)

Other databases:

- EMBL:   BX248356
- RefSeq:   NP_939410.1
- GeneID:   2650815
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP1049
- NMPDR:   fig|257309.1.peg.1001
- HOGENOM:   HBG566588
- OMA:   AVEDELF
- ProtClustDB:   PRK13430
- BioCyc:   CDIP257309:DIP1049-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 29289; Mature: 29289

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAASREALARVTSDLDKALWEAKENAIATAAHTGAELFDVVEVLDGDRALRVAVADSAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
SAEDRAGLVSAVFAGKVSPATLEVLVTSARELWSNPREFRDGLVTLGRRALLRSAEGQGQ
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGQVEDELFRLSRILDKEPELTLLLDDRSTDGAKKRELLAKVLYGKVTAVTEALALQVIG
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRESNAIDDIDALSKEAAALQGHSVAHVVSAGRLNDEQNQALAQKLERIYGRAMSIHSEV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DPSLLGGLVIRVGDEVIDGSTSGKLERLRANLA
CHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MHAASREALARVTSDLDKALWEAKENAIATAAHTGAELFDVVEVLDGDRALRVAVADSAK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
SAEDRAGLVSAVFAGKVSPATLEVLVTSARELWSNPREFRDGLVTLGRRALLRSAEGQGQ
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCC
LGQVEDELFRLSRILDKEPELTLLLDDRSTDGAKKRELLAKVLYGKVTAVTEALALQVIG
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRESNAIDDIDALSKEAAALQGHSVAHVVSAGRLNDEQNQALAQKLERIYGRAMSIHSEV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DPSLLGGLVIRVGDEVIDGSTSGKLERLRANLA
CHHHHHHHHHHCCCHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14602910