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The map label for this gene is alsD [H]

Identifier: 38233585

GI number: 38233585

Start: 960040

End: 960780

Strand: Reverse

Name: alsD [H]

Synonym: DIP0990

Alternate gene names: 38233585

Gene position: 960780-960040 (Counterclockwise)

Preceding gene: 38233586

Following gene: 38233584

Centisome position: 38.61

GC content: 55.74

Gene sequence:

>741_bases
ATGGATGACCATAACGCGCTGCTCGCTGAGCGCCATACGATTTTCCAAAGCTCACTCATGACCGCCCTCCTAGACGGCAT
CTATGACGGTGAGATTTCCATCGGCGAATTACTGGGACACGGTAACTTCGGCATAGGCACATTTGATGCCCTCGACGGGG
AAATGGTCATCCTCGACGGAGTCTGCTACCAACTTCGTGGCGACGGATCCGCCAGTGAAGCAGCGCTTACACAACGCAGT
CCATTCGCTATAGCCACAAACTTTGTGCCACGGCTTAAAGCTCGTGTACCACGAGGCATGCACAGGAGCGAACTCAGTGA
CTTCATCACCTCCCTCCTACCCAGCGAAAACTACATGTATGCGGTACGTATTTCCGGAATGTTCTCATCAGTCAGCGTCC
GCACCGTGACCAAACAAGAACGCCCTTACCGCCCGATGACACAAGCGACTGGCGACGACGCCGAACTCGAATTCACCAAC
GTCTCCGGTGTCGTAGCTGGTTTTAGAACCCCCATCTACGAAAAAGGCATTGGCGTACCTGGCTGCCACGTCCACTTCAT
CGACACCGACCGCACCAGCGGCGGCCACGTCCTCGACTTCACCATGTCTGAAGGCACCATCGAAGTCTGCCCAGGAACCG
ACCTCCAGCTGCGCCTACCGCTTACCCAAGACTTCAGCAAAGCATCCTTGGCGCCAGACGACCTCGACGCACAAATCCAC
GCAACCGAAGTGAAAGGCTAA

Upstream 100 bases:

>100_bases
GGCTTCATCGCACAACAAACCGTCGATGTGTACTCCTCCCTCCTATAGAAAATAGGGGGTCCGCTGCAAAATCCCGCCCA
CACGACTATGGTGGGCGGGC

Downstream 100 bases:

>100_bases
CCCACCGCAATGACACATCGGCCAGAACTCCATGTCACCCCAGAAATCGGAATCCTCGATGCCCCTGCAGGTGCGCTTTT
CGACGGCACCAGGTGGCACC

Product: putative decarboxylase (internal pH control related)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MDDHNALLAERHTIFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVILDGVCYQLRGDGSASEAALTQRS
PFAIATNFVPRLKARVPRGMHRSELSDFITSLLPSENYMYAVRISGMFSSVSVRTVTKQERPYRPMTQATGDDAELEFTN
VSGVVAGFRTPIYEKGIGVPGCHVHFIDTDRTSGGHVLDFTMSEGTIEVCPGTDLQLRLPLTQDFSKASLAPDDLDAQIH
ATEVKG

Sequences:

>Translated_246_residues
MDDHNALLAERHTIFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVILDGVCYQLRGDGSASEAALTQRS
PFAIATNFVPRLKARVPRGMHRSELSDFITSLLPSENYMYAVRISGMFSSVSVRTVTKQERPYRPMTQATGDDAELEFTN
VSGVVAGFRTPIYEKGIGVPGCHVHFIDTDRTSGGHVLDFTMSEGTIEVCPGTDLQLRLPLTQDFSKASLAPDDLDAQIH
ATEVKG
>Mature_246_residues
MDDHNALLAERHTIFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVILDGVCYQLRGDGSASEAALTQRS
PFAIATNFVPRLKARVPRGMHRSELSDFITSLLPSENYMYAVRISGMFSSVSVRTVTKQERPYRPMTQATGDDAELEFTN
VSGVVAGFRTPIYEKGIGVPGCHVHFIDTDRTSGGHVLDFTMSEGTIEVCPGTDLQLRLPLTQDFSKASLAPDDLDAQIH
ATEVKG

Specific function: Converts acetolactate into acetoin, which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage [H]

COG id: COG3527

COG function: function code Q; Alpha-acetolactate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-acetolactate decarboxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005128 [H]

Pfam domain/function: PF03306 AAL_decarboxy [H]

EC number: =4.1.1.5 [H]

Molecular weight: Translated: 26702; Mature: 26702

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDHNALLAERHTIFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVILDG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCEEEEEC
VCYQLRGDGSASEAALTQRSPFAIATNFVPRLKARVPRGMHRSELSDFITSLLPSENYMY
EEEEEECCCCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEE
AVRISGMFSSVSVRTVTKQERPYRPMTQATGDDAELEFTNVSGVVAGFRTPIYEKGIGVP
EEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEHHHCCCHHHCCCCCC
GCHVHFIDTDRTSGGHVLDFTMSEGTIEVCPGTDLQLRLPLTQDFSKASLAPDDLDAQIH
CCEEEEEECCCCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCCHHHCCCCCCCCCEEE
ATEVKG
EEECCC
>Mature Secondary Structure
MDDHNALLAERHTIFQSSLMTALLDGIYDGEISIGELLGHGNFGIGTFDALDGEMVILDG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCEEEEEC
VCYQLRGDGSASEAALTQRSPFAIATNFVPRLKARVPRGMHRSELSDFITSLLPSENYMY
EEEEEECCCCCCHHHHHCCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEE
AVRISGMFSSVSVRTVTKQERPYRPMTQATGDDAELEFTNVSGVVAGFRTPIYEKGIGVP
EEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCEEEHHHCCCHHHCCCCCC
GCHVHFIDTDRTSGGHVLDFTMSEGTIEVCPGTDLQLRLPLTQDFSKASLAPDDLDAQIH
CCEEEEEECCCCCCCEEEEEEECCCEEEECCCCCEEEEECCCCCCHHHCCCCCCCCCEEE
ATEVKG
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377; 10809684 [H]