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The map label for this gene is dapL [H]

Identifier: 38233569

GI number: 38233569

Start: 945034

End: 946134

Strand: Direct

Name: dapL [H]

Synonym: DIP0974

Alternate gene names: 38233569

Gene position: 945034-946134 (Clockwise)

Preceding gene: 38233568

Following gene: 38233570

Centisome position: 37.97

GC content: 59.22

Gene sequence:

>1101_bases
ATGATGACGCGCTTGCCTCTTGGTGCTACTTTGCCTGATTTTCCGTGGGACTCGCTTGCCGATGCCAAAAAGACGGCAAG
TTCTCACCCCGATGGGTTGATTAACCTCTCAGTCGGCAGCCCTGTCGACGAGGTTGCCCCTGGGATTCGGCTTGCTTTGG
CAGAGGCTGCGGCCGCGCCAGGTTATCCGCAGACTATTGGCACCCAAGAGCTGCGCGCTGCCATTGTTGATTCTCTCCAG
CGCCGCTATCACGCAACTTCTCTAGGAGGGGTGTTGCCGGTAGTTGGTACTAAAGAAGCGATTGCTTTGCTTCCCACCCT
CCTAGGGATTCGCGGTACGGTCGTCATCCCTGAGGTGGCGTATCCGACTTATGAGGTGGGTGCTTTGATGGCGGGTGCGA
CCCCGCTGCGTTGCGACGCCCCCCATGAGCTGCCCAACGATGACATCGATTTGGTCTTTATCAATTCCCCGTCGAATCCC
ACGGGCCGTGTAGCTTCTGTTGAGGAGCTGCGTTCCATTGTCGCTTGGGCTCAGGCTAACGACGTGATCGTTGCCTCCGA
CGAGTGTTACCTCGGTTTGGCGTGGGATGGGGAAGCGGTGTCGATTTTGGACCCGCGCGTCAACGATGGCAACCTGTCCA
ACCTCCTAGCGATTCATTCGTTGTCCAAGTCGTCGAATTTGGCGTCGTATCGCGCCGGTTTCTTGGCCGGAGATGAGGCG
CTCATTGCCGAGCTCACCGAAATCCGTAAGCACTCAGGTTTAATGGTCCCAGGCCCCATCCAGGCCGCCATGGTGGAAGC
CTTGCGTGACGACGACCAGGAGGCACTCCAAAAGCTTCGCTACGCCCGTCGACGTGCGCTCCTCATGCGCGCGCTTATCG
ACGCCGGCTTTACCGTCGAACACTCCGAAGCCGGTCTGTACCTGTGGGCCACCCGCGGCGAAAACTGCCGTGCCACCGTC
GACTGGTTTGCCTCTCATGGCATCTTGGTCGCCCCCGGCGACTTTTATGGCCCCGACGCCCACAACTTCGTGCGCGTCGC
TCTGACCACCACTGATGACAATGCCGAAAAAGTGGCGGCCCGCCTCCAAAAGGGGAATTAG

Upstream 100 bases:

>100_bases
GTGGTGCGGCGAAGCTTGGGCCGCAGGATTTCGACGCTGATTTGGTGGCGTCGCTTCCACCGCAGGTTTAACCACTTTTC
CTAGCTAGTTGTAAGGATCG

Downstream 100 bases:

>100_bases
TTACCAGAAGGTCGTCCTCCACGATGTCGTCCCCGAAGGCGAGTACGTGGCGGCGTCGGCAGGCGATAGTCCCTTTAGCC
CAGGGACCCCGCTTGCCCCT

Product: N-succinyldiaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MMTRLPLGATLPDFPWDSLADAKKTASSHPDGLINLSVGSPVDEVAPGIRLALAEAAAAPGYPQTIGTQELRAAIVDSLQ
RRYHATSLGGVLPVVGTKEAIALLPTLLGIRGTVVIPEVAYPTYEVGALMAGATPLRCDAPHELPNDDIDLVFINSPSNP
TGRVASVEELRSIVAWAQANDVIVASDECYLGLAWDGEAVSILDPRVNDGNLSNLLAIHSLSKSSNLASYRAGFLAGDEA
LIAELTEIRKHSGLMVPGPIQAAMVEALRDDDQEALQKLRYARRRALLMRALIDAGFTVEHSEAGLYLWATRGENCRATV
DWFASHGILVAPGDFYGPDAHNFVRVALTTTDDNAEKVAARLQKGN

Sequences:

>Translated_366_residues
MMTRLPLGATLPDFPWDSLADAKKTASSHPDGLINLSVGSPVDEVAPGIRLALAEAAAAPGYPQTIGTQELRAAIVDSLQ
RRYHATSLGGVLPVVGTKEAIALLPTLLGIRGTVVIPEVAYPTYEVGALMAGATPLRCDAPHELPNDDIDLVFINSPSNP
TGRVASVEELRSIVAWAQANDVIVASDECYLGLAWDGEAVSILDPRVNDGNLSNLLAIHSLSKSSNLASYRAGFLAGDEA
LIAELTEIRKHSGLMVPGPIQAAMVEALRDDDQEALQKLRYARRRALLMRALIDAGFTVEHSEAGLYLWATRGENCRATV
DWFASHGILVAPGDFYGPDAHNFVRVALTTTDDNAEKVAARLQKGN
>Mature_366_residues
MMTRLPLGATLPDFPWDSLADAKKTASSHPDGLINLSVGSPVDEVAPGIRLALAEAAAAPGYPQTIGTQELRAAIVDSLQ
RRYHATSLGGVLPVVGTKEAIALLPTLLGIRGTVVIPEVAYPTYEVGALMAGATPLRCDAPHELPNDDIDLVFINSPSNP
TGRVASVEELRSIVAWAQANDVIVASDECYLGLAWDGEAVSILDPRVNDGNLSNLLAIHSLSKSSNLASYRAGFLAGDEA
LIAELTEIRKHSGLMVPGPIQAAMVEALRDDDQEALQKLRYARRRALLMRALIDAGFTVEHSEAGLYLWATRGENCRATV
DWFASHGILVAPGDFYGPDAHNFVRVALTTTDDNAEKVAARLQKGN

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=29.9465240641711, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786816, Length=396, Percent_Identity=22.979797979798, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 39031; Mature: 39031

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTRLPLGATLPDFPWDSLADAKKTASSHPDGLINLSVGSPVDEVAPGIRLALAEAAAAP
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCEEHHHHHHCCC
GYPQTIGTQELRAAIVDSLQRRYHATSLGGVLPVVGTKEAIALLPTLLGIRGTVVIPEVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCEEEECCCC
YPTYEVGALMAGATPLRCDAPHELPNDDIDLVFINSPSNPTGRVASVEELRSIVAWAQAN
CCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
DVIVASDECYLGLAWDGEAVSILDPRVNDGNLSNLLAIHSLSKSSNLASYRAGFLAGDEA
CEEEECCCEEEEEEECCCEEEEECCCCCCCCHHHHHEEHHCCCCCCCHHHHHCCCCCCHH
LIAELTEIRKHSGLMVPGPIQAAMVEALRDDDQEALQKLRYARRRALLMRALIDAGFTVE
HHHHHHHHHHHCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
HSEAGLYLWATRGENCRATVDWFASHGILVAPGDFYGPDAHNFVRVALTTTDDNAEKVAA
ECCCCEEEEEECCCCCEEEHHHHHCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHH
RLQKGN
HHHCCC
>Mature Secondary Structure
MMTRLPLGATLPDFPWDSLADAKKTASSHPDGLINLSVGSPVDEVAPGIRLALAEAAAAP
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHCCCCEEHHHHHHCCC
GYPQTIGTQELRAAIVDSLQRRYHATSLGGVLPVVGTKEAIALLPTLLGIRGTVVIPEVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHCCCCEEEECCCC
YPTYEVGALMAGATPLRCDAPHELPNDDIDLVFINSPSNPTGRVASVEELRSIVAWAQAN
CCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
DVIVASDECYLGLAWDGEAVSILDPRVNDGNLSNLLAIHSLSKSSNLASYRAGFLAGDEA
CEEEECCCEEEEEEECCCEEEEECCCCCCCCHHHHHEEHHCCCCCCCHHHHHCCCCCCHH
LIAELTEIRKHSGLMVPGPIQAAMVEALRDDDQEALQKLRYARRRALLMRALIDAGFTVE
HHHHHHHHHHHCCEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
HSEAGLYLWATRGENCRATVDWFASHGILVAPGDFYGPDAHNFVRVALTTTDDNAEKVAA
ECCCCEEEEEECCCCCEEEHHHHHCCCEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHH
RLQKGN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA