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The map label for this gene is clcB [H]

Identifier: 38233548

GI number: 38233548

Start: 923566

End: 924588

Strand: Reverse

Name: clcB [H]

Synonym: DIP0952

Alternate gene names: 38233548

Gene position: 924588-923566 (Counterclockwise)

Preceding gene: 38233560

Following gene: 38233545

Centisome position: 37.15

GC content: 58.26

Gene sequence:

>1023_bases
ATGGCACTCATCAGCCTAGGAGTAGGAGCACTTGCAGGAACATGCTGGTGGGCACTACGCCGACGTGGCCCCATCGTCAC
CGTCACCGCAGCACTATCCACCGATACGCCCCTACCCTTGTGGCGCACGCTTGCCGACGCCCTCCTACAACTGCTCATCG
TCACCGCAGGAGCCTCACTGGGTAAAGAACAAGCACCTCGACAACTAGCCGCAGCCCTTGCAGAACGCATCGCCCCCGCC
CACAACGACACCGACCGCCATCGTCGTATTCGGCTCCTCGCCGCCGCAGCTGGCGCAGGACTTGCAGCTATGTACCACGT
TCCCATCGCCGGAATCTTCTTCGTCCTTGAGCTCCTCCCCGTTCGACGCGACCGCGCCACGATAGCTACCACCATCGCAG
TGTGCGCCATTGCCACTACAGTCGCATCGCCGGTAGTTCCAGCGCCTTTGTACGGATTTCCTCACGAAGCGCTAGGAGTC
AATGATTTCCTCCCCCTCCTAGTCGTGACAATTGTTGCCACAGTGGTTGCTGTGATGTGGCGTCGTCTGACAGTCACACA
GTTGCAGCGCAGCTATACCGGCCCTTGGCTTGTGATTACTCTCCCACTAGCGCTTGCGATCACGTATGCGGTGGGAACAT
GGTTTCCTGCGGTTCATGGCAACGGTCAGCTCGTACTTGATGTCGCCTTCGGTACTGATATCACCGCCTTAATGGCCTTT
GTACTTCTCCTCGCCAAATTGATGGCAACGCTTGTGTGCATTCGTGCAGGTGCTGTGGGCGGTGTACTGACACCATCACT
TGCTGTTGGGGCGGCAGCCGGAGTGTGCGTTGCTGTTCTTTTTGGCGCTCCGAACGCGGTCATGGCATTGGTTGCTGCCG
CTATCGTGTTGGCGATTACGCAACGGGCTCCGTTGTTTGGCGCGGCGATGGCTATTGAGCTCACCCACCCCGATATATGG
CTTGCGGCCACTGTGGTAGTCACAGCGGCCGCAGGTTTTTGGTGTACGAGAAAAATCAGATAG

Upstream 100 bases:

>100_bases
CATAAGCATCGTCGGTGTTACCACAGGACTCGTCGGAATCCTCACCACACTCCTTCTTCACACCGCAGAACACCAGCTCG
CACACCTCACCCACACCACC

Downstream 100 bases:

>100_bases
CTAGGATTCCTAGACTAGACAAGTGCTCGGGCTTGCCTACCAGCAGCAAAGCGATCGAGCGCGCCAGTTTGTGCCAGCGC
TTTGACTAGAAGGTAGCCAA

Product: putative chloride channel related membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MALISLGVGALAGTCWWALRRRGPIVTVTAALSTDTPLPLWRTLADALLQLLIVTAGASLGKEQAPRQLAAALAERIAPA
HNDTDRHRRIRLLAAAAGAGLAAMYHVPIAGIFFVLELLPVRRDRATIATTIAVCAIATTVASPVVPAPLYGFPHEALGV
NDFLPLLVVTIVATVVAVMWRRLTVTQLQRSYTGPWLVITLPLALAITYAVGTWFPAVHGNGQLVLDVAFGTDITALMAF
VLLLAKLMATLVCIRAGAVGGVLTPSLAVGAAAGVCVAVLFGAPNAVMALVAAAIVLAITQRAPLFGAAMAIELTHPDIW
LAATVVVTAAAGFWCTRKIR

Sequences:

>Translated_340_residues
MALISLGVGALAGTCWWALRRRGPIVTVTAALSTDTPLPLWRTLADALLQLLIVTAGASLGKEQAPRQLAAALAERIAPA
HNDTDRHRRIRLLAAAAGAGLAAMYHVPIAGIFFVLELLPVRRDRATIATTIAVCAIATTVASPVVPAPLYGFPHEALGV
NDFLPLLVVTIVATVVAVMWRRLTVTQLQRSYTGPWLVITLPLALAITYAVGTWFPAVHGNGQLVLDVAFGTDITALMAF
VLLLAKLMATLVCIRAGAVGGVLTPSLAVGAAAGVCVAVLFGAPNAVMALVAAAIVLAITQRAPLFGAAMAIELTHPDIW
LAATVVVTAAAGFWCTRKIR
>Mature_339_residues
ALISLGVGALAGTCWWALRRRGPIVTVTAALSTDTPLPLWRTLADALLQLLIVTAGASLGKEQAPRQLAAALAERIAPAH
NDTDRHRRIRLLAAAAGAGLAAMYHVPIAGIFFVLELLPVRRDRATIATTIAVCAIATTVASPVVPAPLYGFPHEALGVN
DFLPLLVVTIVATVVAVMWRRLTVTQLQRSYTGPWLVITLPLALAITYAVGTWFPAVHGNGQLVLDVAFGTDITALMAFV
LLLAKLMATLVCIRAGAVGGVLTPSLAVGAAAGVCVAVLFGAPNAVMALVAAAIVLAITQRAPLFGAAMAIELTHPDIWL
AATVVVTAAAGFWCTRKIR

Specific function: Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response [H]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 35427; Mature: 35295

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLGVGALAGTCWWALRRRGPIVTVTAALSTDTPLPLWRTLADALLQLLIVTAGASL
CCEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
GKEQAPRQLAAALAERIAPAHNDTDRHRRIRLLAAAAGAGLAAMYHVPIAGIFFVLELLP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VRRDRATIATTIAVCAIATTVASPVVPAPLYGFPHEALGVNDFLPLLVVTIVATVVAVMW
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
RRLTVTQLQRSYTGPWLVITLPLALAITYAVGTWFPAVHGNGQLVLDVAFGTDITALMAF
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHH
VLLLAKLMATLVCIRAGAVGGVLTPSLAVGAAAGVCVAVLFGAPNAVMALVAAAIVLAIT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRAPLFGAAMAIELTHPDIWLAATVVVTAAAGFWCTRKIR
CCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
ALISLGVGALAGTCWWALRRRGPIVTVTAALSTDTPLPLWRTLADALLQLLIVTAGASL
CEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
GKEQAPRQLAAALAERIAPAHNDTDRHRRIRLLAAAAGAGLAAMYHVPIAGIFFVLELLP
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VRRDRATIATTIAVCAIATTVASPVVPAPLYGFPHEALGVNDFLPLLVVTIVATVVAVMW
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
RRLTVTQLQRSYTGPWLVITLPLALAITYAVGTWFPAVHGNGQLVLDVAFGTDITALMAF
HHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHH
VLLLAKLMATLVCIRAGAVGGVLTPSLAVGAAAGVCVAVLFGAPNAVMALVAAAIVLAIT
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QRAPLFGAAMAIELTHPDIWLAATVVVTAAAGFWCTRKIR
CCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA