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The map label for this gene is degP [H]

Identifier: 38233453

GI number: 38233453

Start: 830008

End: 831294

Strand: Direct

Name: degP [H]

Synonym: DIP0856

Alternate gene names: 38233453

Gene position: 830008-831294 (Clockwise)

Preceding gene: 38233452

Following gene: 38233454

Centisome position: 33.35

GC content: 55.87

Gene sequence:

>1287_bases
ATGACAAATCCACAGAACCATGATGACGCCCGCACTTCACCCACCGCCGATCAGACCGCAGCGTTTGATCGGGTGGAGAA
TCCTTACGGAAATGCTCACAACGTGCAAGAAGAACGACTAACTGAGCAATCGCAGCCGTTGGGGGCTCAGGAACCCCCCG
TACCGCTGGAGCCGGAGACGTCGAAACGCGAAAAGCGACGCGTCAGCATCGGCACCGCTGTTGCTATGACACTGGTTGCT
GCCATTGCTTCTGGCACGTTGACTGGGGTTTATTCCACAAACCGTGCGGGTAATTCCGGCTCCACTACACGCACGCAGGT
AGCGGAATCCTTGCGTCAGCCAGTATCTCAAGATCATCCAGCTCCCGTTGAGGGATCGGTTGAAGACGTCGCAGCAAAGG
TATTGCCTTCTGTCGTATCGATTTTGGTGGCCACTCGAAACGGCTCCGCTGAAGGATCTGGCTCCATTATTTCCGAAGAT
GGCTACGTGATGACCAACAACCACGTGGTGGCAGGGGCTGAACAAGGGGCAGCGCGAATATCTGTGACCTTGAACGATGG
CTCTGAGCATCCTGCTGAATTGATAGCTGGCGACCCAAACACAGACGTCGCAGTAATCAAGATCAAAGACGTCAGCGGCT
TGCCTGTTATGAAGTTCGGTGATTCCAACAACCTCACGGTTGGGCAACAAGTGGTTGCCGTGGGTTCGCCGCTGGGGCTT
TCGGCTACGGTCACATCTGGCATCGTGTCAGCGCTGAACCGTCCGGTGCGTGCAGGCGGCTCCGAAACAGGACAATCGTC
GCTTATCGACGCCGTCCAAACCGACGCAGCAATCAACCCAGGCAACTCCGGTGGCCCGTTGGTTGATGCCACCGGAGCCC
TCATCGGCATGAACTCCGTGATTGCCTCGCTCAGCGCAGGCGGCAAGTCGGAATCCGGATCCATAGGCCTAGGCTTTGCC
ATCCCTTCCAACTTTGCTCGTCGCGTAGCCAGCCAGCTCATTGAGAAGGGTTATGCCACCCAACCCATGATTGGTATTCA
GCTCATTTCGAACGCGAACGCCAAAGGTGCTGTAATCGCCGATGTTCAGCCTGATGGTCCAGGCGCTCACGCCGGATTAC
GAGCAGGAGAAGTGATCACCAAAATTAATGACCGCTATGTTGATAGCGCCGATGCTTTGATCGCTGCGGTACGAAGCAGC
GATTTTGGTCAAACAGTTAAGCTCACCGTCCGTGGGGAAAACGACCAAAACGAGCGACAGGTCGACGTAACCCTCACAGG
CGAATAG

Upstream 100 bases:

>100_bases
ACGGCAAATAATACGTTCACAGGAACCTCCCAGCGATTCACGACGCTACCCGCAGTGAGGTTCCAGAACGTCACCAGTAT
GTGGTCCGATAGTATTTACT

Downstream 100 bases:

>100_bases
ACTGCTAGATCAAAGTATCTATTACGAGAAGAGACGCCATGGAGATCACGGACATCACCCAAATGGACAACGTGTTCGAT
TACATCGAACCGGATCCTGA

Product: putative serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTNPQNHDDARTSPTADQTAAFDRVENPYGNAHNVQEERLTEQSQPLGAQEPPVPLEPETSKREKRRVSIGTAVAMTLVA
AIASGTLTGVYSTNRAGNSGSTTRTQVAESLRQPVSQDHPAPVEGSVEDVAAKVLPSVVSILVATRNGSAEGSGSIISED
GYVMTNNHVVAGAEQGAARISVTLNDGSEHPAELIAGDPNTDVAVIKIKDVSGLPVMKFGDSNNLTVGQQVVAVGSPLGL
SATVTSGIVSALNRPVRAGGSETGQSSLIDAVQTDAAINPGNSGGPLVDATGALIGMNSVIASLSAGGKSESGSIGLGFA
IPSNFARRVASQLIEKGYATQPMIGIQLISNANAKGAVIADVQPDGPGAHAGLRAGEVITKINDRYVDSADALIAAVRSS
DFGQTVKLTVRGENDQNERQVDVTLTGE

Sequences:

>Translated_428_residues
MTNPQNHDDARTSPTADQTAAFDRVENPYGNAHNVQEERLTEQSQPLGAQEPPVPLEPETSKREKRRVSIGTAVAMTLVA
AIASGTLTGVYSTNRAGNSGSTTRTQVAESLRQPVSQDHPAPVEGSVEDVAAKVLPSVVSILVATRNGSAEGSGSIISED
GYVMTNNHVVAGAEQGAARISVTLNDGSEHPAELIAGDPNTDVAVIKIKDVSGLPVMKFGDSNNLTVGQQVVAVGSPLGL
SATVTSGIVSALNRPVRAGGSETGQSSLIDAVQTDAAINPGNSGGPLVDATGALIGMNSVIASLSAGGKSESGSIGLGFA
IPSNFARRVASQLIEKGYATQPMIGIQLISNANAKGAVIADVQPDGPGAHAGLRAGEVITKINDRYVDSADALIAAVRSS
DFGQTVKLTVRGENDQNERQVDVTLTGE
>Mature_427_residues
TNPQNHDDARTSPTADQTAAFDRVENPYGNAHNVQEERLTEQSQPLGAQEPPVPLEPETSKREKRRVSIGTAVAMTLVAA
IASGTLTGVYSTNRAGNSGSTTRTQVAESLRQPVSQDHPAPVEGSVEDVAAKVLPSVVSILVATRNGSAEGSGSIISEDG
YVMTNNHVVAGAEQGAARISVTLNDGSEHPAELIAGDPNTDVAVIKIKDVSGLPVMKFGDSNNLTVGQQVVAVGSPLGLS
ATVTSGIVSALNRPVRAGGSETGQSSLIDAVQTDAAINPGNSGGPLVDATGALIGMNSVIASLSAGGKSESGSIGLGFAI
PSNFARRVASQLIEKGYATQPMIGIQLISNANAKGAVIADVQPDGPGAHAGLRAGEVITKINDRYVDSADALIAAVRSSD
FGQTVKLTVRGENDQNERQVDVTLTGE

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=318, Percent_Identity=34.9056603773585, Blast_Score=148, Evalue=9e-36,
Organism=Homo sapiens, GI22129776, Length=318, Percent_Identity=34.2767295597484, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24308541, Length=315, Percent_Identity=34.6031746031746, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=302, Percent_Identity=31.7880794701987, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1789629, Length=285, Percent_Identity=41.4035087719298, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI1786356, Length=287, Percent_Identity=39.7212543554007, Blast_Score=172, Evalue=6e-44,
Organism=Escherichia coli, GI1789630, Length=282, Percent_Identity=34.7517730496454, Blast_Score=139, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24646839, Length=339, Percent_Identity=30.6784660766962, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 43809; Mature: 43678

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPQNHDDARTSPTADQTAAFDRVENPYGNAHNVQEERLTEQSQPLGAQEPPVPLEPET
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
SKREKRRVSIGTAVAMTLVAAIASGTLTGVYSTNRAGNSGSTTRTQVAESLRQPVSQDHP
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
APVEGSVEDVAAKVLPSVVSILVATRNGSAEGSGSIISEDGYVMTNNHVVAGAEQGAARI
CCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCEEEECCEEEEECCCCCEEE
SVTLNDGSEHPAELIAGDPNTDVAVIKIKDVSGLPVMKFGDSNNLTVGQQVVAVGSPLGL
EEEECCCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCCCCC
SATVTSGIVSALNRPVRAGGSETGQSSLIDAVQTDAAINPGNSGGPLVDATGALIGMNSV
HHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHH
IASLSAGGKSESGSIGLGFAIPSNFARRVASQLIEKGYATQPMIGIQLISNANAKGAVIA
HHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEE
DVQPDGPGAHAGLRAGEVITKINDRYVDSADALIAAVRSSDFGQTVKLTVRGENDQNERQ
EECCCCCCCCCCCCHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEE
VDVTLTGE
EEEEEECC
>Mature Secondary Structure 
TNPQNHDDARTSPTADQTAAFDRVENPYGNAHNVQEERLTEQSQPLGAQEPPVPLEPET
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
SKREKRRVSIGTAVAMTLVAAIASGTLTGVYSTNRAGNSGSTTRTQVAESLRQPVSQDHP
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
APVEGSVEDVAAKVLPSVVSILVATRNGSAEGSGSIISEDGYVMTNNHVVAGAEQGAARI
CCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCEEEECCEEEEECCCCCEEE
SVTLNDGSEHPAELIAGDPNTDVAVIKIKDVSGLPVMKFGDSNNLTVGQQVVAVGSPLGL
EEEECCCCCCCHHHCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCCCCC
SATVTSGIVSALNRPVRAGGSETGQSSLIDAVQTDAAINPGNSGGPLVDATGALIGMNSV
HHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHH
IASLSAGGKSESGSIGLGFAIPSNFARRVASQLIEKGYATQPMIGIQLISNANAKGAVIA
HHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCEEEE
DVQPDGPGAHAGLRAGEVITKINDRYVDSADALIAAVRSSDFGQTVKLTVRGENDQNERQ
EECCCCCCCCCCCCHHHHHHHHCHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEE
VDVTLTGE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]