Click here to switch to the map view.

The map label for this gene is nudC [H]

Identifier: 38233331

GI number: 38233331

Start: 699791

End: 700474

Strand: Direct

Name: nudC [H]

Synonym: DIP0725

Alternate gene names: 38233331

Gene position: 699791-700474 (Clockwise)

Preceding gene: 38233330

Following gene: 38233332

Centisome position: 28.12

GC content: 53.51

Gene sequence:

>684_bases
GTGCCAGTAGCACACGGAACGCCGGTCACCACCACCCCCTGCCCACATATCGCTACCTATCCAGTAACGAACGACCTGTG
TGTACAACGAGTGTCAGACGCGGAAGCAGAAGCTGTTACAGGAGAAACCAAGCGGGTGACCGAGGGCTGGGTAATGAAGG
CTATCGCTGTACTACATCATCGAGAAAACACTCTGTTTGATCCTTTGACAGGTGGCCCACTGGACTTTCGCAACGACTCC
ATTGCAGGAGCAACCGAAACTGGTAGAGAAGTCTTTCCTCGTATCGATCCCGCAGTAATCGGGCTAATCGAACTTGCAGG
ACAAGACCGCATACTCATCGCTGAAAACGCCCAGCGTCGCGGTTTCTACTCGCTCATTGCAGGCTATGTGGGACTTGGTG
AAACTTGTGAGGAAGCCATGGTGCGAGAAGCTCTTGAAGAAACCGGACGTCGTATTTCGCAGGTGCGCTATGTGCGCAGT
CAGCCTTGGCCCTACAACGGTGCACTCATGATGGGCATGGTGGCAACCACAACAGATGAGCACCCCATACAACCCCTCGA
TGGCGAGCTAGCGAGAATAACGTGGGCGTCGCGAAGCGAACTCCGCGAAGGGGTATTTACCCTGCCACATAGGAATTCTC
TAGCGTTCCAATTGATCACAGAATGGGTGGGACAACATGATTAA

Upstream 100 bases:

>100_bases
GAAACAGTAGAACCAGGTGATCGTTTGCTCTACGTTCGTCGCGTGTTTAGTGAGGATGTTCGCGATTAACACCTGCCTTC
GTGTCGACTCTGCAGGACGA

Downstream 100 bases:

>100_bases
CTTGGATGATCTTGACGATGACCAGCGTGCAGCCGCCGAGGCGCCGCGTGGTCCGGTAGCCATTTTGGCAGGCGCAGGGA
CAGGTAAAACTCGTACGATC

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPVAHGTPVTTTPCPHIATYPVTNDLCVQRVSDAEAEAVTGETKRVTEGWVMKAIAVLHHRENTLFDPLTGGPLDFRNDS
IAGATETGREVFPRIDPAVIGLIELAGQDRILIAENAQRRGFYSLIAGYVGLGETCEEAMVREALEETGRRISQVRYVRS
QPWPYNGALMMGMVATTTDEHPIQPLDGELARITWASRSELREGVFTLPHRNSLAFQLITEWVGQHD

Sequences:

>Translated_227_residues
MPVAHGTPVTTTPCPHIATYPVTNDLCVQRVSDAEAEAVTGETKRVTEGWVMKAIAVLHHRENTLFDPLTGGPLDFRNDS
IAGATETGREVFPRIDPAVIGLIELAGQDRILIAENAQRRGFYSLIAGYVGLGETCEEAMVREALEETGRRISQVRYVRS
QPWPYNGALMMGMVATTTDEHPIQPLDGELARITWASRSELREGVFTLPHRNSLAFQLITEWVGQHD
>Mature_226_residues
PVAHGTPVTTTPCPHIATYPVTNDLCVQRVSDAEAEAVTGETKRVTEGWVMKAIAVLHHRENTLFDPLTGGPLDFRNDSI
AGATETGREVFPRIDPAVIGLIELAGQDRILIAENAQRRGFYSLIAGYVGLGETCEEAMVREALEETGRRISQVRYVRSQ
PWPYNGALMMGMVATTTDEHPIQPLDGELARITWASRSELREGVFTLPHRNSLAFQLITEWVGQHD

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=140, Percent_Identity=31.4285714285714, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI50593112, Length=149, Percent_Identity=32.2147651006711, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI48994995, Length=85, Percent_Identity=40, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321371, Length=151, Percent_Identity=33.7748344370861, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 25078; Mature: 24947

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVAHGTPVTTTPCPHIATYPVTNDLCVQRVSDAEAEAVTGETKRVTEGWVMKAIAVLHH
CCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
RENTLFDPLTGGPLDFRNDSIAGATETGREVFPRIDPAVIGLIELAGQDRILIAENAQRR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
GFYSLIAGYVGLGETCEEAMVREALEETGRRISQVRYVRSQPWPYNGALMMGMVATTTDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCC
HPIQPLDGELARITWASRSELREGVFTLPHRNSLAFQLITEWVGQHD
CCCCCCCCCEEEEEHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
PVAHGTPVTTTPCPHIATYPVTNDLCVQRVSDAEAEAVTGETKRVTEGWVMKAIAVLHH
CCCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
RENTLFDPLTGGPLDFRNDSIAGATETGREVFPRIDPAVIGLIELAGQDRILIAENAQRR
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCCC
GFYSLIAGYVGLGETCEEAMVREALEETGRRISQVRYVRSQPWPYNGALMMGMVATTTDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCC
HPIQPLDGELARITWASRSELREGVFTLPHRNSLAFQLITEWVGQHD
CCCCCCCCCEEEEEHHHHHHHHHCCEECCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]