Click here to switch to the map view.

The map label for this gene is secA

Identifier: 38233306

GI number: 38233306

Start: 674230

End: 676791

Strand: Direct

Name: secA

Synonym: DIP0699

Alternate gene names: 38233306

Gene position: 674230-676791 (Clockwise)

Preceding gene: 38233305

Following gene: 38233307

Centisome position: 27.09

GC content: 53.51

Gene sequence:

>2562_bases
GTGTTTGGACTTTCCAAGATGCTTCGCGTTGGCGAAGGACGGGCCGTCAAGCGCCTGAAGAAGATCGCTGATGATGTGAT
CGCACTCGAGGCGGATTACACCGATCTTACTGACGAGGAGCTCAAGGCTAAGACCCATGAATTTCAAGAGCGCATTGCAC
AAGGTGAATCAGTAGATGACCTCTTGCTTGAGGCATTTGCGGTTGCCCGTGAGGCGTCGTGGCGCGTGCTGGGTCAGAAG
CACTACCCAGTGCAGATTATGGGTGGTGCTGCGTTGCACTTTGGCAACGTAGCCGAGATGCGTACTGGTGAGGGTAAGAC
CTTGACCTGTGTGCTTCCGGCATACCTCAATGCTCTCGAAGGCAAGGGTGTTCATGTTGTTACCGTGAACGACTACTTGG
CTAAGCGTGACGCTGAGTGGATGGGTCGTGTGCACCGCTGGCTAGGCCTTAATGTTGGTGTGATCTTGGCGAACATGCAG
CCTGCGGAGCGTCGTGAAGCCTACAATGCTGACATCACTTACGGCACCAACAACGAGTTGGGCTTTGACTACCTGCGCGA
TAACATGGTGCGCTCTCTCGATGAGCTCGTTCAGCGCGGTCATCACTATGCGATCGTTGACGAGGTTGACTCCATTCTTA
TCGACGAGGCACGTACGCCACTGATTATTTCTGGTCCAGTAGATGGATCATCGCAGTGGTATAGCGTGTTCGCTCAGATC
GTTCCTCGTATGACTCGCGACATCCACTATGAAGTGGATAACCGTAAACGTACCGTCGGTGTACGTGAAGAAGGCGTTGC
CTTTGTCGAAGATCAGCTCGGAATTGATAACCTTTACGCTCCTGAGCACTCCCAGCTGGTGAGCTACCTGAACAATGCCA
TCAAGGCCAAAGAGCTGTTCAACCGTGACAAGGACTACATCGTGCGCAACGGTGAAGTTCTGATCGTTGATGATTTCACT
GGTCGTGTTCTTGATGGACGTCGCTACAATGAGGGTATGCACCAAGCGATCGAGGCGAAAGAAAACGTCGAGATCAAAAA
CGAGAACCAGACTCTGGCAACCATCACGTTGCAGAACTACTTCCGCCTGTACGACAAACTCTCGGGTATGACGGGTACTG
CAGAAACGGAAGCATCTGAGCTCCACCAGATCTACAAGCTGGACGTTATCCCGATTCCTACCAACCGTCCGAACCAGCGT
GAAGACATGACTGACTTGGTGTACAAGACCCAAGAAGCCAAGTTTGCTGCCGTGGTGGATGACATCTCTGAACGCGTAAC
AAAGGGACAGCCTGTTCTCGTTGGTACCACCTCTGTTGAGCGCTCCGAGTATCTCTCCCAGCTGCTGCAGCGCCGTGGAA
TCAAGCACAGCGTGCTTAACGCTAAGTTCCACGAGCAGGAAGCCCAGATCGTGGCCAAGGCGGGTCTGCCTGGTGCAGTT
ACCGTGGCAACAAACATGGCCGGTCGTGGTACCGACATCGTGCTCGGTGGCAACGCAGACATCATTGCTGACATTAACCT
GCGTGAGCGTGGCCTCAATCCAGTTGATACTCCTGAAGAGTACGAGGCAGCGTGGGATGCCGAGCTGGCACGCGTCAAGG
AAAAAGGTGCTGAGCTAGCGGAGAAGGTTCGTGAAGCAGGCGGCCTCTACGTGCTGGGTACCGAGCGCCACGAGTCGCGT
CGTATTGATAACCAGTTGCGTGGTCGCGCTGGTCGTCAGGGTGATCCTGGCACCACTCGTTTCTACCTGTCTATGCGTGA
TGACCTCATGGTTCGTTTCGTTGGCCAGACCATGGAAAACATGATGAACCGCCTCAACGTTCCAGACGATGTACCTATCG
AAGCCAAGATGGTGACCAACTCCATCAAGTCGGCCCAGACATCGGTGGAGAATCAGAACTTTGAGATGCGTAAGAACGTC
TTGAAGTACGACGAGGTCATGAATGAGCAGCGCAAGGTCATTTACACCGAGCGTCGTGAGATCCTCGAATCGGCTGACAT
CGCGGCCGATATTCAAAAGATGATCGATGACACCATCGGTGCCTATGTCGATGCTGCGACCGCGACCGGCTACGTTGAGG
ACTGGGATCTAGAAACCCTGTGGAACGCTCTCGAGTCTCTCTATGGCCCATCCTTTAGCGCACAAGAGCTCATTGATGGC
GATTCCTATGGTGAATCTGGTGAGCTTTCTGCTTCCGATCTGCGTAAAGCTGTTCTGGAAGACGCACACAAGCAGTATGC
GGAGCTAGAGGAAAATGTCACCGCTATCGGTGGCGAGGCACAGATGCGCAACATTGAGCGCATGGTTATCCTGCCGGTTA
TCGATACCAAGTGGCGCGAACACCTCTACGAGATGGATTACCTCAAGGAAGGTATCGGTCTGCGGGCAATGGCTCAGCGT
GACCCACTGGTCGAGTACCAAAAGGAGGGTGGCGACATGTTCAATGCCATGAAAGACGCCGTAAAGGAAGAAACCGTTCG
CCAACTATTCTTGCTGCGCAAGCAGTTTGCAGTTGCAAATGAGCAGCCAGCGGAAACTGAAGAAGGCACCGTAGAAGCCT
AA

Upstream 100 bases:

>100_bases
CAGATCTCCGGCACTCGGTGATCTGGGTTCTTGGTATAAGGTAGCAATGACCTAGAATGTCTACGTTAAGACGAAACTAT
TTTCAAAGGATTCAGTACAC

Downstream 100 bases:

>100_bases
TTCTTCCACCGCCACAACAACGCCGCCTCCTGTTGTTTTAGGGAGGCGGCGTTGTTGTTTCTATGGCGAAGGTTTATTAG
GCGGTGGCTCGATAAGTCGC

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 853; Mature: 853

Protein sequence:

>853_residues
MFGLSKMLRVGEGRAVKRLKKIADDVIALEADYTDLTDEELKAKTHEFQERIAQGESVDDLLLEAFAVAREASWRVLGQK
HYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLNVGVILANMQ
PAERREAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQI
VPRMTRDIHYEVDNRKRTVGVREEGVAFVEDQLGIDNLYAPEHSQLVSYLNNAIKAKELFNRDKDYIVRNGEVLIVDDFT
GRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNYFRLYDKLSGMTGTAETEASELHQIYKLDVIPIPTNRPNQR
EDMTDLVYKTQEAKFAAVVDDISERVTKGQPVLVGTTSVERSEYLSQLLQRRGIKHSVLNAKFHEQEAQIVAKAGLPGAV
TVATNMAGRGTDIVLGGNADIIADINLRERGLNPVDTPEEYEAAWDAELARVKEKGAELAEKVREAGGLYVLGTERHESR
RIDNQLRGRAGRQGDPGTTRFYLSMRDDLMVRFVGQTMENMMNRLNVPDDVPIEAKMVTNSIKSAQTSVENQNFEMRKNV
LKYDEVMNEQRKVIYTERREILESADIAADIQKMIDDTIGAYVDAATATGYVEDWDLETLWNALESLYGPSFSAQELIDG
DSYGESGELSASDLRKAVLEDAHKQYAELEENVTAIGGEAQMRNIERMVILPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNAMKDAVKEETVRQLFLLRKQFAVANEQPAETEEGTVEA

Sequences:

>Translated_853_residues
MFGLSKMLRVGEGRAVKRLKKIADDVIALEADYTDLTDEELKAKTHEFQERIAQGESVDDLLLEAFAVAREASWRVLGQK
HYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLNVGVILANMQ
PAERREAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQI
VPRMTRDIHYEVDNRKRTVGVREEGVAFVEDQLGIDNLYAPEHSQLVSYLNNAIKAKELFNRDKDYIVRNGEVLIVDDFT
GRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNYFRLYDKLSGMTGTAETEASELHQIYKLDVIPIPTNRPNQR
EDMTDLVYKTQEAKFAAVVDDISERVTKGQPVLVGTTSVERSEYLSQLLQRRGIKHSVLNAKFHEQEAQIVAKAGLPGAV
TVATNMAGRGTDIVLGGNADIIADINLRERGLNPVDTPEEYEAAWDAELARVKEKGAELAEKVREAGGLYVLGTERHESR
RIDNQLRGRAGRQGDPGTTRFYLSMRDDLMVRFVGQTMENMMNRLNVPDDVPIEAKMVTNSIKSAQTSVENQNFEMRKNV
LKYDEVMNEQRKVIYTERREILESADIAADIQKMIDDTIGAYVDAATATGYVEDWDLETLWNALESLYGPSFSAQELIDG
DSYGESGELSASDLRKAVLEDAHKQYAELEENVTAIGGEAQMRNIERMVILPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNAMKDAVKEETVRQLFLLRKQFAVANEQPAETEEGTVEA
>Mature_853_residues
MFGLSKMLRVGEGRAVKRLKKIADDVIALEADYTDLTDEELKAKTHEFQERIAQGESVDDLLLEAFAVAREASWRVLGQK
HYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALEGKGVHVVTVNDYLAKRDAEWMGRVHRWLGLNVGVILANMQ
PAERREAYNADITYGTNNELGFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQI
VPRMTRDIHYEVDNRKRTVGVREEGVAFVEDQLGIDNLYAPEHSQLVSYLNNAIKAKELFNRDKDYIVRNGEVLIVDDFT
GRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNYFRLYDKLSGMTGTAETEASELHQIYKLDVIPIPTNRPNQR
EDMTDLVYKTQEAKFAAVVDDISERVTKGQPVLVGTTSVERSEYLSQLLQRRGIKHSVLNAKFHEQEAQIVAKAGLPGAV
TVATNMAGRGTDIVLGGNADIIADINLRERGLNPVDTPEEYEAAWDAELARVKEKGAELAEKVREAGGLYVLGTERHESR
RIDNQLRGRAGRQGDPGTTRFYLSMRDDLMVRFVGQTMENMMNRLNVPDDVPIEAKMVTNSIKSAQTSVENQNFEMRKNV
LKYDEVMNEQRKVIYTERREILESADIAADIQKMIDDTIGAYVDAATATGYVEDWDLETLWNALESLYGPSFSAQELIDG
DSYGESGELSASDLRKAVLEDAHKQYAELEENVTAIGGEAQMRNIERMVILPVIDTKWREHLYEMDYLKEGIGLRAMAQR
DPLVEYQKEGGDMFNAMKDAVKEETVRQLFLLRKQFAVANEQPAETEEGTVEA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=856, Percent_Identity=49.1822429906542, Blast_Score=796, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_CORDI (Q6NIR8)

Other databases:

- EMBL:   BX248355
- RefSeq:   NP_939073.1
- HSSP:   P0A5Y8
- ProteinModelPortal:   Q6NIR8
- SMR:   Q6NIR8
- GeneID:   2649082
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0699
- NMPDR:   fig|257309.1.peg.664
- HOGENOM:   HBG284200
- OMA:   IEAKMVS
- PhylomeDB:   Q6NIR8
- ProtClustDB:   PRK12904
- BioCyc:   CDIP257309:DIP0699-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 96095; Mature: 96095

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLSKMLRVGEGRAVKRLKKIADDVIALEADYTDLTDEELKAKTHEFQERIAQGESVDD
CCCHHHHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LLLEAFAVAREASWRVLGQKHYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALE
HHHHHHHHHHHCCHHEECCCCCCEEEECCCEEECCCHHHEECCCCCEEEEEHHHHHHHHC
GKGVHVVTVNDYLAKRDAEWMGRVHRWLGLNVGVILANMQPAERREAYNADITYGTNNEL
CCCEEEEEECHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCEEECCCCCC
GFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQI
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
VPRMTRDIHYEVDNRKRTVGVREEGVAFVEDQLGIDNLYAPEHSQLVSYLNNAIKAKELF
HHHHHHHHEEEECCCEEECCCCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NRDKDYIVRNGEVLIVDDFTGRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNY
CCCCCEEEECCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHH
FRLYDKLSGMTGTAETEASELHQIYKLDVIPIPTNRPNQREDMTDLVYKTQEAKFAAVVD
HHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
DISERVTKGQPVLVGTTSVERSEYLSQLLQRRGIKHSVLNAKFHEQEAQIVAKAGLPGAV
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
TVATNMAGRGTDIVLGGNADIIADINLRERGLNPVDTPEEYEAAWDAELARVKEKGAELA
EEEECCCCCCCEEEECCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKVREAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGTTRFYLSMRDDLMVRFVGQTMEN
HHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHH
MMNRLNVPDDVPIEAKMVTNSIKSAQTSVENQNFEMRKNVLKYDEVMNEQRKVIYTERRE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILESADIAADIQKMIDDTIGAYVDAATATGYVEDWDLETLWNALESLYGPSFSAQELIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC
DSYGESGELSASDLRKAVLEDAHKQYAELEENVTAIGGEAQMRNIERMVILPVIDTKWRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHCCCEEEEEEECCHHHHH
HLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNAMKDAVKEETVRQLFLLRKQFAVAN
HHHHHHHHHHCCCCEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQPAETEEGTVEA
CCCCCCCCCCCCC
>Mature Secondary Structure
MFGLSKMLRVGEGRAVKRLKKIADDVIALEADYTDLTDEELKAKTHEFQERIAQGESVDD
CCCHHHHHHCCCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHH
LLLEAFAVAREASWRVLGQKHYPVQIMGGAALHFGNVAEMRTGEGKTLTCVLPAYLNALE
HHHHHHHHHHHCCHHEECCCCCCEEEECCCEEECCCHHHEECCCCCEEEEEHHHHHHHHC
GKGVHVVTVNDYLAKRDAEWMGRVHRWLGLNVGVILANMQPAERREAYNADITYGTNNEL
CCCEEEEEECHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCCEEECCCCCC
GFDYLRDNMVRSLDELVQRGHHYAIVDEVDSILIDEARTPLIISGPVDGSSQWYSVFAQI
CHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHH
VPRMTRDIHYEVDNRKRTVGVREEGVAFVEDQLGIDNLYAPEHSQLVSYLNNAIKAKELF
HHHHHHHHEEEECCCEEECCCCCCCCEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NRDKDYIVRNGEVLIVDDFTGRVLDGRRYNEGMHQAIEAKENVEIKNENQTLATITLQNY
CCCCCEEEECCCEEEEECCCCCEECCCHHHHHHHHHHHHHHCCEEECCCCEEEEEEHHHH
FRLYDKLSGMTGTAETEASELHQIYKLDVIPIPTNRPNQREDMTDLVYKTQEAKFAAVVD
HHHHHHHCCCCCCCCHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHH
DISERVTKGQPVLVGTTSVERSEYLSQLLQRRGIKHSVLNAKFHEQEAQIVAKAGLPGAV
HHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHCCCCCEE
TVATNMAGRGTDIVLGGNADIIADINLRERGLNPVDTPEEYEAAWDAELARVKEKGAELA
EEEECCCCCCCEEEECCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EKVREAGGLYVLGTERHESRRIDNQLRGRAGRQGDPGTTRFYLSMRDDLMVRFVGQTMEN
HHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHH
MMNRLNVPDDVPIEAKMVTNSIKSAQTSVENQNFEMRKNVLKYDEVMNEQRKVIYTERRE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILESADIAADIQKMIDDTIGAYVDAATATGYVEDWDLETLWNALESLYGPSFSAQELIDG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC
DSYGESGELSASDLRKAVLEDAHKQYAELEENVTAIGGEAQMRNIERMVILPVIDTKWRE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHCCCEEEEEEECCHHHHH
HLYEMDYLKEGIGLRAMAQRDPLVEYQKEGGDMFNAMKDAVKEETVRQLFLLRKQFAVAN
HHHHHHHHHHCCCCEEHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EQPAETEEGTVEA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14602910