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The map label for this gene is secY [H]

Identifier: 38233149

GI number: 38233149

Start: 509759

End: 511081

Strand: Direct

Name: secY [H]

Synonym: DIP0540

Alternate gene names: 38233149

Gene position: 509759-511081 (Clockwise)

Preceding gene: 38233146

Following gene: 38233150

Centisome position: 20.48

GC content: 52.46

Gene sequence:

>1323_bases
GTGTCTGCGATTTTTCAGGCATTCCGAGATGCGGATCTTCGCAAGAAGATTCTGATCACCATCGCGTTGATCATCTTGTA
CCGAATCGGTGCGCAGATCCCGTCTCCGGGTGTTGATTACGCGTCGATTAGCGGTCGGCTTCGTGAGCTGACGTCGGACT
CTTCGAGCGTCTACTCACTGATTAACCTGTTTTCGGGCGGAGCCCTGCTGCAGCTGTCAATCTTTGCTATTGGTGTGATG
CCATACATTACGGCGTCGATCATCGTGCAGCTGCTAACGGTTGTGATCCCTAAATTTGAGGAACTCAAAAAAGAGGGACA
ATCCGGTCAAGCAAAGATGGATCAGTACACGCGTTACCTCACCTTGGGTCTTGCGTTGCTGCAGTCCTCGGGCATCGTTG
CTCTTGCTGACCGTGAGCAGCTGTTGGGTAGCGGTGTTTCGGTGCTGAAGGAAGACCGTAACCTGTGGACCTTGGTCATG
CTGGTGTTGGTCATGTCCGCTGGTGCCATCTTGGTGATGTGGCTCGGTGAGATCATCACTGAGCGCGGTATCGGTAACGG
CATGTCCCTACTGATCTTCGCGGGTATCGCAACTCGTATTCCTTCTGATGGCGCCAACATCTTGAGTTCTTCTGGCGGCG
TTGTGTTCGCTGTGGTTCTTGTTGCTGTGATCGTCTTGGTCGTGGGCGTGGTCTTCGTTGAGCAAGGCCAGCGCCGTATT
CCAGTGCAGTACGCAAAGCGCATGGTGGGACGTCGTCAGTACGGTGGCTCTTCTACCTACCTGCCTCTTAAGGTCAACCA
GGCTGGCGTTATCCCCGTGATCTTCGCATCCTCTTTGATCTACATGCCAGTGCTGATCACCCAGATCATCAACTCCGGCT
CCCACGAGGTTTCCGATAACTGGTGGCAGCGCAACGTTATTCAGTACCTGCAAACGCCATCCTCATGGCAGTACATCGTG
TTGTACTTTGCGCTTATCATTTTCTTCTCTTACTTCTACGTTTCCGTGCAATACGACCCCAATGAGCAAGCGGACAACAT
GAAGAAGTACGGTGGTTTCATCCCAGGAATCCGCCCAGGTCGTCCTACGGCGGAGTATCTTGGATATGTGATGAACCGAC
TCCTGTTCGTCGGTGCGCTGTATCTTGGCATCATCGCTGTTTTGCCTAACATCGCTCTCGACTTGGGCGTTGGGGCAAGC
TCTGCTGGATCAACACCATTCGGCGGTACTGCAATTTTGATTATGGTTTCCGTGGCTTTGACAACCGTCAAGCAGATCGA
AAGCCAGCTACTGCAAAGCAACTACGAAGGACTTCTTAAATAA

Upstream 100 bases:

>100_bases
GCGGAATGTCGAATGTGGCTTCACATTTTCTAAGGCTTAGGGCATACGTTTACACACATCTCCTATCGCTTTGGGGGTGG
TAGGAGAACCAGGAGGCTAA

Downstream 100 bases:

>100_bases
TGCGACTCGTACTTCTTGGACCTCCCGGTGCTGGCAAAGGCACCCAAGCGGCTATCCTCTCCGAAAAGCTGCGCATTCCT
CACATCTCTACCGGTGACCT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSLINLFSGGALLQLSIFAIGVM
PYITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYLTLGLALLQSSGIVALADREQLLGSGVSVLKEDRNLWTLVM
LVLVMSAGAILVMWLGEIITERGIGNGMSLLIFAGIATRIPSDGANILSSSGGVVFAVVLVAVIVLVVGVVFVEQGQRRI
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGSHEVSDNWWQRNVIQYLQTPSSWQYIV
LYFALIIFFSYFYVSVQYDPNEQADNMKKYGGFIPGIRPGRPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGAS
SAGSTPFGGTAILIMVSVALTTVKQIESQLLQSNYEGLLK

Sequences:

>Translated_440_residues
MSAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSLINLFSGGALLQLSIFAIGVM
PYITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYLTLGLALLQSSGIVALADREQLLGSGVSVLKEDRNLWTLVM
LVLVMSAGAILVMWLGEIITERGIGNGMSLLIFAGIATRIPSDGANILSSSGGVVFAVVLVAVIVLVVGVVFVEQGQRRI
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGSHEVSDNWWQRNVIQYLQTPSSWQYIV
LYFALIIFFSYFYVSVQYDPNEQADNMKKYGGFIPGIRPGRPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGAS
SAGSTPFGGTAILIMVSVALTTVKQIESQLLQSNYEGLLK
>Mature_439_residues
SAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSLINLFSGGALLQLSIFAIGVMP
YITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYLTLGLALLQSSGIVALADREQLLGSGVSVLKEDRNLWTLVML
VLVMSAGAILVMWLGEIITERGIGNGMSLLIFAGIATRIPSDGANILSSSGGVVFAVVLVAVIVLVVGVVFVEQGQRRIP
VQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGSHEVSDNWWQRNVIQYLQTPSSWQYIVL
YFALIIFFSYFYVSVQYDPNEQADNMKKYGGFIPGIRPGRPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGASS
AGSTPFGGTAILIMVSVALTTVKQIESQLLQSNYEGLLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=438, Percent_Identity=44.7488584474886, Blast_Score=299, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47843; Mature: 47712

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSL
CHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
INLFSGGALLQLSIFAIGVMPYITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHH
TLGLALLQSSGIVALADREQLLGSGVSVLKEDRNLWTLVMLVLVMSAGAILVMWLGEIIT
HHHHHHHHCCCEEEECCHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERGIGNGMSLLIFAGIATRIPSDGANILSSSGGVVFAVVLVAVIVLVVGVVFVEQGQRRI
HCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGSHEVSDN
CHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WWQRNVIQYLQTPSSWQYIVLYFALIIFFSYFYVSVQYDPNEQADNMKKYGGFIPGIRPG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCCCCC
RPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGASSAGSTPFGGTAILIMVSVAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TTVKQIESQLLQSNYEGLLK
HHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SAIFQAFRDADLRKKILITIALIILYRIGAQIPSPGVDYASISGRLRELTSDSSSVYSL
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHH
INLFSGGALLQLSIFAIGVMPYITASIIVQLLTVVIPKFEELKKEGQSGQAKMDQYTRYL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHH
TLGLALLQSSGIVALADREQLLGSGVSVLKEDRNLWTLVMLVLVMSAGAILVMWLGEIIT
HHHHHHHHCCCEEEECCHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
ERGIGNGMSLLIFAGIATRIPSDGANILSSSGGVVFAVVLVAVIVLVVGVVFVEQGQRRI
HCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PVQYAKRMVGRRQYGGSSTYLPLKVNQAGVIPVIFASSLIYMPVLITQIINSGSHEVSDN
CHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WWQRNVIQYLQTPSSWQYIVLYFALIIFFSYFYVSVQYDPNEQADNMKKYGGFIPGIRPG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHCCCCCCCCCC
RPTAEYLGYVMNRLLFVGALYLGIIAVLPNIALDLGVGASSAGSTPFGGTAILIMVSVAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHH
TTVKQIESQLLQSNYEGLLK
HHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8112597; 12948626 [H]