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The map label for this gene is macB [H]

Identifier: 38233097

GI number: 38233097

Start: 450449

End: 451759

Strand: Direct

Name: macB [H]

Synonym: DIP0485

Alternate gene names: 38233097

Gene position: 450449-451759 (Clockwise)

Preceding gene: 38233096

Following gene: 38233098

Centisome position: 18.1

GC content: 50.57

Gene sequence:

>1311_bases
ATGAGCGTTCTTGAATCAGTTTCTTTAGCCCTTGGAAGCCTTCGCACCAACAAGATGCGATCAGCTCTGACACTGCTGGG
CGTGATTATCGGCATCGCCTCAGTCATTGCCATCTTGACGCTAGGACATGCGCTGAAAACCCAAACCACAAGCGGTTTGG
AAGGCATTGGCATCAACGACTACAACGCTGACGTTCGTGAGCGAACCCCTGAAGGCGAACCCGAACCAGAAGGCTTTAAT
TTTGGCCCACCTGTAACCGAACCCGATGCTCTGATCACACCAGAGATGATCGATGACCTCCGCTCGCAATTTGGGCCGGA
TATCTCCGAGATACAAGTCGGTGGATATGGCGGAACACCAGCAACTGCAAGCACCGACCTTGATGCAAATAAAGAGCTCA
AGGGCGTTGTCCGAGGAATCAACGTGGACTACCAACGCACCAAAAGCGTGAAAATCGGATGGGGAAGAGAAATCACCGAT
GAGGACATCGACGGTGACCGTCCAGTGGCTGTTGTTCCTGAAAAGCTTGCAACTTCATTCTACGGTAGCGATCCCGCAGC
AGCGCTGGGCAACAGCGTGACGATAGAAACTGACTTTGGTACTGCAGATTTTCAGATCGTGGGAGTGACAAAGAAGCCCG
AAGAAAAAGGCGGTCTTTTAAGTTTTTCTGATAATGAAGTAGAAATTCTTGTACCTTACCCTTCCGAAGCTAAGGTCGCA
GAGATCTCGGGTGTATTCCCTGGGATTAGTATTCGGCTTGCTAGCCCCACAGGAGGTTCGCAAACAGAACGTAATGAGCA
TGATGCTCAAGTGAAAAAGCGACTACAGGCATTTTTTGATGAGCGTTACCAAGACAATAAAGACTATAAGGTCAAGGTGA
CAGATCAGAAGCAGGACTTAGCATCGGTGAATAAGATTTTGACGTCGATTAGCGCGGCTATTGCGGCAATCGGTGGAATC
TCACTGCTGGTTGGCGGTATTGGCGTTATGAACATCATGCTGATTACCGTGACCGAACGCACCAGAGAAATTGGTGTGCG
TAAAGCCTTGGGTGCTACGCGCCGCGACATCCGCTTGCAGTTCGTTGTTGAGGCCATGATCGTGTGCCTGATGGGTGGCT
TGTTGGGCGTGATATTCGGTGGGGCGGTAGGCATGCTCGGTGCGAAATTGATGGGAGAATTTGTCTTCCCACCACTGAGC
GGCATTGTTATTTCGTTGGTGTTCTCCTTGGCCATTGGCCTGTTCTTTGGTTCTTACCCCGCAGGCAAAGCTGCCAAGCT
CAACCCTATTGAGGCTCTTCGCTACGAATAG

Upstream 100 bases:

>100_bases
ACAACCCCGAGCTAGCTGCCGAAACTACTCGGGTAGCTACTATGCGTGACGGCATGTTTGTTGACGAAGATATCTTTCAC
TTTCATACGACGGGGCAACA

Downstream 100 bases:

>100_bases
TTGAGAAGCGGGGTGGGGTTGTGGTTAAATGTTCAGGTTGCCTGCATTGGTCGATCGTTAGTGTGTTAGTTTCCGGACAC
AGCGATCGAAACCCCTCGAC

Product: ABC transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSVLESVSLALGSLRTNKMRSALTLLGVIIGIASVIAILTLGHALKTQTTSGLEGIGINDYNADVRERTPEGEPEPEGFN
FGPPVTEPDALITPEMIDDLRSQFGPDISEIQVGGYGGTPATASTDLDANKELKGVVRGINVDYQRTKSVKIGWGREITD
EDIDGDRPVAVVPEKLATSFYGSDPAAALGNSVTIETDFGTADFQIVGVTKKPEEKGGLLSFSDNEVEILVPYPSEAKVA
EISGVFPGISIRLASPTGGSQTERNEHDAQVKKRLQAFFDERYQDNKDYKVKVTDQKQDLASVNKILTSISAAIAAIGGI
SLLVGGIGVMNIMLITVTERTREIGVRKALGATRRDIRLQFVVEAMIVCLMGGLLGVIFGGAVGMLGAKLMGEFVFPPLS
GIVISLVFSLAIGLFFGSYPAGKAAKLNPIEALRYE

Sequences:

>Translated_436_residues
MSVLESVSLALGSLRTNKMRSALTLLGVIIGIASVIAILTLGHALKTQTTSGLEGIGINDYNADVRERTPEGEPEPEGFN
FGPPVTEPDALITPEMIDDLRSQFGPDISEIQVGGYGGTPATASTDLDANKELKGVVRGINVDYQRTKSVKIGWGREITD
EDIDGDRPVAVVPEKLATSFYGSDPAAALGNSVTIETDFGTADFQIVGVTKKPEEKGGLLSFSDNEVEILVPYPSEAKVA
EISGVFPGISIRLASPTGGSQTERNEHDAQVKKRLQAFFDERYQDNKDYKVKVTDQKQDLASVNKILTSISAAIAAIGGI
SLLVGGIGVMNIMLITVTERTREIGVRKALGATRRDIRLQFVVEAMIVCLMGGLLGVIFGGAVGMLGAKLMGEFVFPPLS
GIVISLVFSLAIGLFFGSYPAGKAAKLNPIEALRYE
>Mature_435_residues
SVLESVSLALGSLRTNKMRSALTLLGVIIGIASVIAILTLGHALKTQTTSGLEGIGINDYNADVRERTPEGEPEPEGFNF
GPPVTEPDALITPEMIDDLRSQFGPDISEIQVGGYGGTPATASTDLDANKELKGVVRGINVDYQRTKSVKIGWGREITDE
DIDGDRPVAVVPEKLATSFYGSDPAAALGNSVTIETDFGTADFQIVGVTKKPEEKGGLLSFSDNEVEILVPYPSEAKVAE
ISGVFPGISIRLASPTGGSQTERNEHDAQVKKRLQAFFDERYQDNKDYKVKVTDQKQDLASVNKILTSISAAIAAIGGIS
LLVGGIGVMNIMLITVTERTREIGVRKALGATRRDIRLQFVVEAMIVCLMGGLLGVIFGGAVGMLGAKLMGEFVFPPLSG
IVISLVFSLAIGLFFGSYPAGKAAKLNPIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=438, Percent_Identity=28.7671232876712, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46364; Mature: 46233

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLESVSLALGSLRTNKMRSALTLLGVIIGIASVIAILTLGHALKTQTTSGLEGIGIND
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
YNADVRERTPEGEPEPEGFNFGPPVTEPDALITPEMIDDLRSQFGPDISEIQVGGYGGTP
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHEEECCCCCCC
ATASTDLDANKELKGVVRGINVDYQRTKSVKIGWGREITDEDIDGDRPVAVVPEKLATSF
CCCCCCCCCCHHHHHHHHCCCCCHHHCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
YGSDPAAALGNSVTIETDFGTADFQIVGVTKKPEEKGGLLSFSDNEVEILVPYPSEAKVA
CCCCCHHHCCCCEEEEECCCCCCEEEEECCCCCHHCCCEEEECCCCEEEEEECCCCCCHH
EISGVFPGISIRLASPTGGSQTERNEHDAQVKKRLQAFFDERYQDNKDYKVKVTDQKQDL
HHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
ASVNKILTSISAAIAAIGGISLLVGGIGVMNIMLITVTERTREIGVRKALGATRRDIRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHCCHHHHHHHH
FVVEAMIVCLMGGLLGVIFGGAVGMLGAKLMGEFVFPPLSGIVISLVFSLAIGLFFGSYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
AGKAAKLNPIEALRYE
CCCCCCCCCHHHHCCC
>Mature Secondary Structure 
SVLESVSLALGSLRTNKMRSALTLLGVIIGIASVIAILTLGHALKTQTTSGLEGIGIND
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
YNADVRERTPEGEPEPEGFNFGPPVTEPDALITPEMIDDLRSQFGPDISEIQVGGYGGTP
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHEEECCCCCCC
ATASTDLDANKELKGVVRGINVDYQRTKSVKIGWGREITDEDIDGDRPVAVVPEKLATSF
CCCCCCCCCCHHHHHHHHCCCCCHHHCCEEEECCCCCCCCCCCCCCCCEEECCHHHHHHH
YGSDPAAALGNSVTIETDFGTADFQIVGVTKKPEEKGGLLSFSDNEVEILVPYPSEAKVA
CCCCCHHHCCCCEEEEECCCCCCEEEEECCCCCHHCCCEEEECCCCEEEEEECCCCCCHH
EISGVFPGISIRLASPTGGSQTERNEHDAQVKKRLQAFFDERYQDNKDYKVKVTDQKQDL
HHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHH
ASVNKILTSISAAIAAIGGISLLVGGIGVMNIMLITVTERTREIGVRKALGATRRDIRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHCCHHHHHHHH
FVVEAMIVCLMGGLLGVIFGGAVGMLGAKLMGEFVFPPLSGIVISLVFSLAIGLFFGSYP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
AGKAAKLNPIEALRYE
CCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]