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The map label for this gene is nrdD [C]

Identifier: 38233077

GI number: 38233077

Start: 434314

End: 436098

Strand: Reverse

Name: nrdD [C]

Synonym: DIP0465

Alternate gene names: 38233077

Gene position: 436098-434314 (Counterclockwise)

Preceding gene: 38233104

Following gene: 38233076

Centisome position: 17.52

GC content: 54.29

Gene sequence:

>1785_bases
ATGAGTGATTCCCAAATTAATAGTCGAACGACTATCGACGAGTACCTTTCTCGCGCCGATTGGCGTGTCAATGCCAACGC
CAACCAGGACTATTCCTTGGGCGGAATGATCCTCAACGCCGCTGGAAAAGTCACGGCTAATTACTGGCTCGACCAAGTAT
TTAGCCCAGCAGCAAGTGCCGCTCACCGTGAAGGCTCTATCCACATCCACGACCTCGATATGCTCTCCGGATACTGCGCC
GGCTGGTCCCTACGCCAACTCCTTGAAGAAGGCTTCGGTGGCGTACCTGGCACTATCTCGTCTCGCCCACCGAAGCACTT
CTCGTCGGCATGCGGCCAGATTGTTAATTTTTTGGGCACTCTCCAAAACGAGTGGGCAGGCGCACAGGCATTCAGCTCCT
TTGACACCTACATGGCACCATTTGTACGTCTAGATAACCTCTCCTATGACGAGATCGTCCAGGACATGCAGGAGTTCATT
TTCAATCTGAACGTTCCATCCCGCTGGGGCACTCAGACACCTTTTACCAACCTGACCTTTGACTGGACCTGCCCAGCCGA
TCTTAAGGACTCGGTGCCGTTTATCGGGGAAGAACCTGTGGACTTCACCTACGGCGAGCTCCAAGAAGAAATGGACCTGA
TCAACCGCGCATTCATTCAGGTGATGTCGGCAGGCGATGCCGATGGTCGGCCGTTTACGTTCCCCATCCCCACATATAAC
ATCACTAAAGACTTTGATTGGGATTCCCCCAATACCGAGGCCTTGTTCACCATGACCGCGAAGTACGGTCTTCCCTACTT
CCAGAATTTCATCAACTCCGATCTGGACCCCGGCATGATCCGTTCCATGTGTTGCCGTTTGCAACTTGATCTTCGCGAGT
TGCTCAAACGCGGCAATGGTTTGTTCGGTTCGGCGGAATTGACTGGTTCCATCGGCGTAGTCACACTCAACTGCGCACGT
TTGGGTTACCTCTATGCCGGTGATGAACAAGCCCTGCTGGGCGCAGTAGATGAGCTCATCGAGTTGGGAATCGATACTCT
AGAGCGCCGCCGGGATTTCGTCGCAACGCATATGAGGCAAGGCCTCTACCCTTATAGCGCTCGCTGGCTACCTAGCTTGG
ACAACCATTTTTCCACGATCGGCGTTAACGGCTGCAATGAGATGATCAGAAATTTCACTCACGACGCCTACAATCTCACC
GATCCGCAAGGCCATGCCCAGGTCGCGCGACTTCTCGACCACATCAATGCCCGCCTCGTGCAAGCACAGGAGCGCACCGG
ACACCTGTTTAACCTTGAGGCAACCCCAGCCGAAGGCACAACCTACCGATTGGCTAAAGAAGATCTCAAGCGTTACCCCG
ATATGTTGCACGCCGGCACGCCGGAGGAGCCCTACTACACCAACTCTTCGCAACTGCCAGTCTCGCACACCCCGGATCCT
TTCGAGGCCCTCGCTTTGCAGGAGGACTTGCAGTCGAAGTACACCGGTGGCACGGTGTTGCACCTTTATATGGGCGCTGC
AATGAGCGATGGTAAGGCTTGTGCGGCTCTCGTTCGTCGCGCCTTGACCAACTTCCATCTGCCGTACATCACGATCACCC
CAACGTTTTCTATTTGCCCAGATCATGGATATATTTCCGGCGAGCACCCTGAGTGCCCACAGTGCGGTGCTACGACAGAG
ATGTGGACGCGCGTGATGGGTTATTTCCGCCCGGTACAAAGTTTTAATACCGGAAAGAAGGGCGAGTTCCATGAGCGCAC
CTACTTTGCCGAAGCACTTATCTGA

Upstream 100 bases:

>100_bases
AGCACATTCTCACACAAGTACCACTACATATTGATTTAGTGAGTTTTTGCACAACTATATCTTGTAGTTTTTGGGGATCT
CAAGCCTTAAGTTGTTCCAT

Downstream 100 bases:

>100_bases
TCTGCCCATCGCCGGAATTATTCCGTTTTCTGCGACTGATTGGCCTGGCAAGCTAACGATCACCGCGTTTACACAGGGGT
GCCCGTTGCGCTGCGTGTAT

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MSDSQINSRTTIDEYLSRADWRVNANANQDYSLGGMILNAAGKVTANYWLDQVFSPAASAAHREGSIHIHDLDMLSGYCA
GWSLRQLLEEGFGGVPGTISSRPPKHFSSACGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRLDNLSYDEIVQDMQEFI
FNLNVPSRWGTQTPFTNLTFDWTCPADLKDSVPFIGEEPVDFTYGELQEEMDLINRAFIQVMSAGDADGRPFTFPIPTYN
ITKDFDWDSPNTEALFTMTAKYGLPYFQNFINSDLDPGMIRSMCCRLQLDLRELLKRGNGLFGSAELTGSIGVVTLNCAR
LGYLYAGDEQALLGAVDELIELGIDTLERRRDFVATHMRQGLYPYSARWLPSLDNHFSTIGVNGCNEMIRNFTHDAYNLT
DPQGHAQVARLLDHINARLVQAQERTGHLFNLEATPAEGTTYRLAKEDLKRYPDMLHAGTPEEPYYTNSSQLPVSHTPDP
FEALALQEDLQSKYTGGTVLHLYMGAAMSDGKACAALVRRALTNFHLPYITITPTFSICPDHGYISGEHPECPQCGATTE
MWTRVMGYFRPVQSFNTGKKGEFHERTYFAEALI

Sequences:

>Translated_594_residues
MSDSQINSRTTIDEYLSRADWRVNANANQDYSLGGMILNAAGKVTANYWLDQVFSPAASAAHREGSIHIHDLDMLSGYCA
GWSLRQLLEEGFGGVPGTISSRPPKHFSSACGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRLDNLSYDEIVQDMQEFI
FNLNVPSRWGTQTPFTNLTFDWTCPADLKDSVPFIGEEPVDFTYGELQEEMDLINRAFIQVMSAGDADGRPFTFPIPTYN
ITKDFDWDSPNTEALFTMTAKYGLPYFQNFINSDLDPGMIRSMCCRLQLDLRELLKRGNGLFGSAELTGSIGVVTLNCAR
LGYLYAGDEQALLGAVDELIELGIDTLERRRDFVATHMRQGLYPYSARWLPSLDNHFSTIGVNGCNEMIRNFTHDAYNLT
DPQGHAQVARLLDHINARLVQAQERTGHLFNLEATPAEGTTYRLAKEDLKRYPDMLHAGTPEEPYYTNSSQLPVSHTPDP
FEALALQEDLQSKYTGGTVLHLYMGAAMSDGKACAALVRRALTNFHLPYITITPTFSICPDHGYISGEHPECPQCGATTE
MWTRVMGYFRPVQSFNTGKKGEFHERTYFAEALI
>Mature_593_residues
SDSQINSRTTIDEYLSRADWRVNANANQDYSLGGMILNAAGKVTANYWLDQVFSPAASAAHREGSIHIHDLDMLSGYCAG
WSLRQLLEEGFGGVPGTISSRPPKHFSSACGQIVNFLGTLQNEWAGAQAFSSFDTYMAPFVRLDNLSYDEIVQDMQEFIF
NLNVPSRWGTQTPFTNLTFDWTCPADLKDSVPFIGEEPVDFTYGELQEEMDLINRAFIQVMSAGDADGRPFTFPIPTYNI
TKDFDWDSPNTEALFTMTAKYGLPYFQNFINSDLDPGMIRSMCCRLQLDLRELLKRGNGLFGSAELTGSIGVVTLNCARL
GYLYAGDEQALLGAVDELIELGIDTLERRRDFVATHMRQGLYPYSARWLPSLDNHFSTIGVNGCNEMIRNFTHDAYNLTD
PQGHAQVARLLDHINARLVQAQERTGHLFNLEATPAEGTTYRLAKEDLKRYPDMLHAGTPEEPYYTNSSQLPVSHTPDPF
EALALQEDLQSKYTGGTVLHLYMGAAMSDGKACAALVRRALTNFHLPYITITPTFSICPDHGYISGEHPECPQCGATTEM
WTRVMGYFRPVQSFNTGKKGEFHERTYFAEALI

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 66431; Mature: 66300

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSQINSRTTIDEYLSRADWRVNANANQDYSLGGMILNAAGKVTANYWLDQVFSPAASA
CCCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
AHREGSIHIHDLDMLSGYCAGWSLRQLLEEGFGGVPGTISSRPPKHFSSACGQIVNFLGT
HHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LQNEWAGAQAFSSFDTYMAPFVRLDNLSYDEIVQDMQEFIFNLNVPSRWGTQTPFTNLTF
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
DWTCPADLKDSVPFIGEEPVDFTYGELQEEMDLINRAFIQVMSAGDADGRPFTFPIPTYN
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC
ITKDFDWDSPNTEALFTMTAKYGLPYFQNFINSDLDPGMIRSMCCRLQLDLRELLKRGNG
CCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LFGSAELTGSIGVVTLNCARLGYLYAGDEQALLGAVDELIELGIDTLERRRDFVATHMRQ
CEECCEECCCCEEEEEEHHHEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
GLYPYSARWLPSLDNHFSTIGVNGCNEMIRNFTHDAYNLTDPQGHAQVARLLDHINARLV
CCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QAQERTGHLFNLEATPAEGTTYRLAKEDLKRYPDMLHAGTPEEPYYTNSSQLPVSHTPDP
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
FEALALQEDLQSKYTGGTVLHLYMGAAMSDGKACAALVRRALTNFHLPYITITPTFSICP
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECC
DHGYISGEHPECPQCGATTEMWTRVMGYFRPVQSFNTGKKGEFHERTYFAEALI
CCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDSQINSRTTIDEYLSRADWRVNANANQDYSLGGMILNAAGKVTANYWLDQVFSPAASA
CCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHH
AHREGSIHIHDLDMLSGYCAGWSLRQLLEEGFGGVPGTISSRPPKHFSSACGQIVNFLGT
HHCCCCEEEEEHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LQNEWAGAQAFSSFDTYMAPFVRLDNLSYDEIVQDMQEFIFNLNVPSRWGTQTPFTNLTF
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEE
DWTCPADLKDSVPFIGEEPVDFTYGELQEEMDLINRAFIQVMSAGDADGRPFTFPIPTYN
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCC
ITKDFDWDSPNTEALFTMTAKYGLPYFQNFINSDLDPGMIRSMCCRLQLDLRELLKRGNG
CCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LFGSAELTGSIGVVTLNCARLGYLYAGDEQALLGAVDELIELGIDTLERRRDFVATHMRQ
CEECCEECCCCEEEEEEHHHEEEEEECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
GLYPYSARWLPSLDNHFSTIGVNGCNEMIRNFTHDAYNLTDPQGHAQVARLLDHINARLV
CCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QAQERTGHLFNLEATPAEGTTYRLAKEDLKRYPDMLHAGTPEEPYYTNSSQLPVSHTPDP
HHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
FEALALQEDLQSKYTGGTVLHLYMGAAMSDGKACAALVRRALTNFHLPYITITPTFSICP
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCEEECC
DHGYISGEHPECPQCGATTEMWTRVMGYFRPVQSFNTGKKGEFHERTYFAEALI
CCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]