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The map label for this gene is rpoB

Identifier: 38233060

GI number: 38233060

Start: 409723

End: 413250

Strand: Direct

Name: rpoB

Synonym: DIP0446

Alternate gene names: 38233060

Gene position: 409723-413250 (Clockwise)

Preceding gene: 38233059

Following gene: 38233061

Centisome position: 16.46

GC content: 58.02

Gene sequence:

>3528_bases
GTGGTCAATATTGCGGGGCCACCGCCGCGTGAGGTGCTGGAAGGACCCATCTTGGCAGTCTCCCGCCAGACCAAGGCCAA
CATCCCTGGGGCCCCCGAACGCAAGTCGTTCGCAAAGATTACGGAACCAATCGAGGTTCCGGGGCTTCTCGATATTCAGC
TCAACTCCTTTGCATGGTTGATTGGTACGCCTGAGTGGCGCGCCCGCCAGCAAGAAGAGCTGGGCGACTCGGTTCGCGTA
ACAAGCGGACTTGAAGACATCTTGGAGGAGCTATCTCCTATCCAGGATTATTCCGGAAATATGTCGCTGTCTCTTTCTGA
GCCTCGCTTCGAGGACATGAAGAACACTATTGATGAGTGCAAAGACAAAGACATCAACTACTCCGCGCCACTGTATGTGA
CCGCAGAGTTCATCAACAACGAAACCCAAGAGATCAAATCGCAGACCGTATTCATCGGCGACTTCCCGATGATGACGGAC
AAGGGCACGTTCATTGTGAACGGTACCGAGCGTGTTGTTGTCTCTCAGCTGGTTCGTTCTCCTGGCGTGTACTTTGATCA
GACGATCGATAAGTCCACCGAGCGTCCACTGCACTCCGTGAAGGTCATTCCTTCCCGCGGTGCATGGCTCGAGTTCGACG
TGGATAAGCGTGACACCGTTGGTGTGCGTATCGACCGCAAGCGTCGTCAGCCTGTGACCGTTTTGCTCAAGGCCCTTGGT
TGGACCACTGAGCAGATCACGGAGCGCTTCGGCTTCTCTGAGATCATGATGTCCACCCTCGAGTCCGACGGTGTATCTAA
TACCGACGAGGCTTTGCTGGAAATCTACCGCAAGCAGCGTCCAGGTGAGCAGCCTACCCGCGACTTGGCACAGTCCCTGC
TGGACAACTCTTTCTTCCGCGCAAAGCGCTACGACCTAGCAAAGGTGGGCCGCTACAAGGTCAACCGCAAGCTGGGCTTG
GGCGGCGACAACGAGGGCCTCATGACCCTCACCGAAGAAGACATCGCAACCACCTTGGAGTACTTGGTACGCCTGCACGC
AGGTGAAACCACCATGACGTCGCCAACCGGCGAGGTCATCCCAGTGGAAACCGATGACATCGACCACTTCGGTAACCGTC
GTCTGCGTACCGTCGGCGAGCTGATCCAAAACCAGGTTCGTGTGGGTCTTTCCCGCATGGAGCGCGTTGTTCGCGAGCGC
ATGACCACTCAGGATGCTGAGTCGATCACCCCTACCTCGCTGATCAACGTTCGCCCTGTTTCTGCCGCCATCCGCGAGTT
CTTCGGAACCTCGCAGCTATCGCAGTTCATGGACCAGAACAACTCTCTGTCCGGTCTGACCCACAAGCGTCGTCTCTCCG
CACTGGGCCCAGGTGGCCTGTCGCGTGAGCGCGCCGGCATTGAGGTCCGAGACGTTCACGCTTCTCACTACGGCCGTATG
TGCCCAATTGAGACTCCTGAAGGTCCAAACATTGGTCTGATCGGTTCGCTTGCGTCCTACGCTCGCGTCAACGCCTTCGG
CTTCATCGAAACGCCATACCGCAAAGTAGAAAACGGCGTTCTGACTGACCAGATCGACTACCTGACCGCTGATGAGGAAG
ATCGCTTCGTCGTCGCGCAGGCAAACGTCGAGCATGACGCTGACGGCAAGATCACCGCAGACAGCGTAACCGTGCGTGTG
AAGAACGGCGACATCCAGGTCGTCGCACCGGAATCCGTCGATTACCTCGACGTTTCGCCACGCCAGATGGTTTCTGTGGC
AACCGCCATGATTCCATTCCTCGAGCACGACGACGCTAACCGCGCCTTGATGGGTGCGAACATGCAGCGTCAGGCTGTGC
CACTCGTACGTTCTGAGGCACCATTCGTTGGCACCGGTATGGAGCGCGCAGCTGCCTACGATGCTGGTGACTTGATCATC
AACAAGAAGGGCGGCGTGGTTGAAAACGTCTCCGCAGACATCATCACCGTGATGGCTGACGACGGAACCCGCGAAACCTA
CATCCTGCGTAAGTTCGAGCGCACCAACCAAGGCACCTGCTACAACCAGACGCCGCTGGTAAACATCGGCGATCGGGTAG
AGGCCGGTCAGGTTCTCGCCGACGGCCCAGGTACGCACAACGGTGAAATGTCCCTCGGACGCAACCTCCTCGTGGCTTTC
ATGCCATGGGAAGGCCACAACTACGAGGACGCTATTATCCTGAACCAGCGCGTGGTCGAAGAGGATATCCTCACCTCGAT
CCACATCGAAGAGCATGAGATCGATGCTCGCGACACCAAGCTGGGACCTGAGGAAATCACCCGCGAGATCCCGAACGTTT
CCGAAGACGTGCTCAAGGACCTCGACGAGCGCGGTATCGTTCGCATCGGTGCGGACGTTCGCGACGGCGACATCCTCGTC
GGTAAGGTCACCCCGAAGGGTGAAACCGAGCTGACCCCTGAAGAGCGTCTGCTTCGCGCCATCTTCGGCGAGAAGGCACG
CGAAGTCCGCGACACCTCCATGAAGGTACCTCACGGTGAAACCGGTAAGGTCATCGGCGTTCGCCGCTTCTCGCGTGACG
ACGATGACGATCTCGCACCAGGCGTCAACGAGATGATTCGCGTCTACGTTGCCCAAAAGCGCAAGATCCAGGACGGCGAC
AAGCTCGCTGGTCGCCACGGCAACAAGGGTGTTGTGGGCAAGATCCTGCCTCAGGAAGATATGCCATTCATGCCAGACGG
CACCCCAGTGGACATCATCCTGAACACCCACGGTGTGCCTCGTCGTATGAACATCGGCCAGGTGCTCGAGGTTCACTTGG
GCTGGTTGGCCGCTGCCGGTTGGAAGATCGACACCGAAGACCCAGCAAACGCTGAATTGCTCAAGACCCTCCCAGAGGAT
CTCTACGACGTCCCAGCTGGTTCACTGACCGCAACCCCAGTGTTCGACGGTGCTACCAACGAGGAAATCGCAGGTCTGTT
GGGCAATTCTCGTCCAAACCGCGACGGCGACGTCATGGTCGACGAAAACGGCAAGGCTACGCTGTTCGACGGCCGCTCCG
GCGAACCATTCCCATACCCAGTGTCTGTTGGCTACATGTACATCCTGAAGCTGCACCACTTGGTTGATGAGAAGATCCAC
GCACGTTCCACCGGTCCTTACTCCATGATTACCCAGCAGCCACTGGGTGGTAAGGCACAGTTCGGTGGTCAGCGCTTCGG
CGAGATGGAGGTGTGGGCAATGCAGGCGTACGGCGCTGCCTACACCCTGCAGGAACTCCTGACCATCAAGTCTGACGACG
TGGTTGGCCGCGTCAAGGTGTACGAGGCCATTGTGAAGGGCGAAAACATTCCGGATCCTGGTATCCCAGAGTCCTTCAAG
GTGCTCCTGAAAGAGCTCCAGTCGCTGTGCTTGAACGTGGAGGTTCTCTCCGCAGACGGCACCCCGATGGAGTTGTCTGG
ATCGGATGACGACGAGTTCGATCAGGCCGGTGCCTCCTTGGGCATCAACCTGTCGCGCGACGAACGTTCCGACGCAGACA
TCGCCTAA

Upstream 100 bases:

>100_bases
GATCAGTACGGTGTAAAAAACCAATTTGACAAGGTCATTCCGTGCTATCTGGGTATGAGAGCTCCTCTGCAGACCGAATG
CTCAATTACCAGCGGAAATG

Downstream 100 bases:

>100_bases
CGCCAGGCAAGAAACTACAGAATCAGCACTAAACGAAAGGGAGTTACGTGATCGACGTCAACTTCTTCGACGAGCTTCGA
ATCGGCCTGGCCACTGCCGA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1175; Mature: 1175

Protein sequence:

>1175_residues
MVNIAGPPPREVLEGPILAVSRQTKANIPGAPERKSFAKITEPIEVPGLLDIQLNSFAWLIGTPEWRARQQEELGDSVRV
TSGLEDILEELSPIQDYSGNMSLSLSEPRFEDMKNTIDECKDKDINYSAPLYVTAEFINNETQEIKSQTVFIGDFPMMTD
KGTFIVNGTERVVVSQLVRSPGVYFDQTIDKSTERPLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALG
WTTEQITERFGFSEIMMSTLESDGVSNTDEALLEIYRKQRPGEQPTRDLAQSLLDNSFFRAKRYDLAKVGRYKVNRKLGL
GGDNEGLMTLTEEDIATTLEYLVRLHAGETTMTSPTGEVIPVETDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRER
MTTQDAESITPTSLINVRPVSAAIREFFGTSQLSQFMDQNNSLSGLTHKRRLSALGPGGLSRERAGIEVRDVHASHYGRM
CPIETPEGPNIGLIGSLASYARVNAFGFIETPYRKVENGVLTDQIDYLTADEEDRFVVAQANVEHDADGKITADSVTVRV
KNGDIQVVAPESVDYLDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPFVGTGMERAAAYDAGDLII
NKKGGVVENVSADIITVMADDGTRETYILRKFERTNQGTCYNQTPLVNIGDRVEAGQVLADGPGTHNGEMSLGRNLLVAF
MPWEGHNYEDAIILNQRVVEEDILTSIHIEEHEIDARDTKLGPEEITREIPNVSEDVLKDLDERGIVRIGADVRDGDILV
GKVTPKGETELTPEERLLRAIFGEKAREVRDTSMKVPHGETGKVIGVRRFSRDDDDDLAPGVNEMIRVYVAQKRKIQDGD
KLAGRHGNKGVVGKILPQEDMPFMPDGTPVDIILNTHGVPRRMNIGQVLEVHLGWLAAAGWKIDTEDPANAELLKTLPED
LYDVPAGSLTATPVFDGATNEEIAGLLGNSRPNRDGDVMVDENGKATLFDGRSGEPFPYPVSVGYMYILKLHHLVDEKIH
ARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGENIPDPGIPESFK
VLLKELQSLCLNVEVLSADGTPMELSGSDDDEFDQAGASLGINLSRDERSDADIA

Sequences:

>Translated_1175_residues
MVNIAGPPPREVLEGPILAVSRQTKANIPGAPERKSFAKITEPIEVPGLLDIQLNSFAWLIGTPEWRARQQEELGDSVRV
TSGLEDILEELSPIQDYSGNMSLSLSEPRFEDMKNTIDECKDKDINYSAPLYVTAEFINNETQEIKSQTVFIGDFPMMTD
KGTFIVNGTERVVVSQLVRSPGVYFDQTIDKSTERPLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALG
WTTEQITERFGFSEIMMSTLESDGVSNTDEALLEIYRKQRPGEQPTRDLAQSLLDNSFFRAKRYDLAKVGRYKVNRKLGL
GGDNEGLMTLTEEDIATTLEYLVRLHAGETTMTSPTGEVIPVETDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRER
MTTQDAESITPTSLINVRPVSAAIREFFGTSQLSQFMDQNNSLSGLTHKRRLSALGPGGLSRERAGIEVRDVHASHYGRM
CPIETPEGPNIGLIGSLASYARVNAFGFIETPYRKVENGVLTDQIDYLTADEEDRFVVAQANVEHDADGKITADSVTVRV
KNGDIQVVAPESVDYLDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPFVGTGMERAAAYDAGDLII
NKKGGVVENVSADIITVMADDGTRETYILRKFERTNQGTCYNQTPLVNIGDRVEAGQVLADGPGTHNGEMSLGRNLLVAF
MPWEGHNYEDAIILNQRVVEEDILTSIHIEEHEIDARDTKLGPEEITREIPNVSEDVLKDLDERGIVRIGADVRDGDILV
GKVTPKGETELTPEERLLRAIFGEKAREVRDTSMKVPHGETGKVIGVRRFSRDDDDDLAPGVNEMIRVYVAQKRKIQDGD
KLAGRHGNKGVVGKILPQEDMPFMPDGTPVDIILNTHGVPRRMNIGQVLEVHLGWLAAAGWKIDTEDPANAELLKTLPED
LYDVPAGSLTATPVFDGATNEEIAGLLGNSRPNRDGDVMVDENGKATLFDGRSGEPFPYPVSVGYMYILKLHHLVDEKIH
ARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGENIPDPGIPESFK
VLLKELQSLCLNVEVLSADGTPMELSGSDDDEFDQAGASLGINLSRDERSDADIA
>Mature_1175_residues
MVNIAGPPPREVLEGPILAVSRQTKANIPGAPERKSFAKITEPIEVPGLLDIQLNSFAWLIGTPEWRARQQEELGDSVRV
TSGLEDILEELSPIQDYSGNMSLSLSEPRFEDMKNTIDECKDKDINYSAPLYVTAEFINNETQEIKSQTVFIGDFPMMTD
KGTFIVNGTERVVVSQLVRSPGVYFDQTIDKSTERPLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALG
WTTEQITERFGFSEIMMSTLESDGVSNTDEALLEIYRKQRPGEQPTRDLAQSLLDNSFFRAKRYDLAKVGRYKVNRKLGL
GGDNEGLMTLTEEDIATTLEYLVRLHAGETTMTSPTGEVIPVETDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRER
MTTQDAESITPTSLINVRPVSAAIREFFGTSQLSQFMDQNNSLSGLTHKRRLSALGPGGLSRERAGIEVRDVHASHYGRM
CPIETPEGPNIGLIGSLASYARVNAFGFIETPYRKVENGVLTDQIDYLTADEEDRFVVAQANVEHDADGKITADSVTVRV
KNGDIQVVAPESVDYLDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPFVGTGMERAAAYDAGDLII
NKKGGVVENVSADIITVMADDGTRETYILRKFERTNQGTCYNQTPLVNIGDRVEAGQVLADGPGTHNGEMSLGRNLLVAF
MPWEGHNYEDAIILNQRVVEEDILTSIHIEEHEIDARDTKLGPEEITREIPNVSEDVLKDLDERGIVRIGADVRDGDILV
GKVTPKGETELTPEERLLRAIFGEKAREVRDTSMKVPHGETGKVIGVRRFSRDDDDDLAPGVNEMIRVYVAQKRKIQDGD
KLAGRHGNKGVVGKILPQEDMPFMPDGTPVDIILNTHGVPRRMNIGQVLEVHLGWLAAAGWKIDTEDPANAELLKTLPED
LYDVPAGSLTATPVFDGATNEEIAGLLGNSRPNRDGDVMVDENGKATLFDGRSGEPFPYPVSVGYMYILKLHHLVDEKIH
ARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMQAYGAAYTLQELLTIKSDDVVGRVKVYEAIVKGENIPDPGIPESFK
VLLKELQSLCLNVEVLSADGTPMELSGSDDDEFDQAGASLGINLSRDERSDADIA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI4505941, Length=456, Percent_Identity=28.7280701754386, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI238908505, Length=440, Percent_Identity=28.1818181818182, Blast_Score=148, Evalue=4e-35,
Organism=Homo sapiens, GI238908503, Length=440, Percent_Identity=28.1818181818182, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI33469941, Length=394, Percent_Identity=29.6954314720812, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI212286172, Length=394, Percent_Identity=29.6954314720812, Blast_Score=127, Evalue=5e-29,
Organism=Escherichia coli, GI1790419, Length=616, Percent_Identity=56.8181818181818, Blast_Score=690, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=446, Percent_Identity=29.5964125560538, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI25144348, Length=581, Percent_Identity=25.6454388984509, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17506623, Length=218, Percent_Identity=33.9449541284404, Blast_Score=107, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6324725, Length=446, Percent_Identity=28.47533632287, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324781, Length=443, Percent_Identity=28.2167042889391, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6325267, Length=384, Percent_Identity=26.8229166666667, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136444, Length=449, Percent_Identity=27.6169265033408, Blast_Score=150, Evalue=6e-36,
Organism=Drosophila melanogaster, GI17647877, Length=445, Percent_Identity=29.6629213483146, Blast_Score=147, Evalue=5e-35,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_CORDI (P60280)

Other databases:

- EMBL:   BX248355
- RefSeq:   NP_938827.1
- ProteinModelPortal:   P60280
- GeneID:   2650616
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0446
- NMPDR:   fig|257309.1.peg.418
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   P60280
- ProtClustDB:   PRK00405
- BioCyc:   CDIP257309:DIP0446-MONOMER
- BRENDA:   2.7.7.6
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 129793; Mature: 129793

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNIAGPPPREVLEGPILAVSRQTKANIPGAPERKSFAKITEPIEVPGLLDIQLNSFAWL
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCEEEE
IGTPEWRARQQEELGDSVRVTSGLEDILEELSPIQDYSGNMSLSLSEPRFEDMKNTIDEC
EECCHHHHHHHHHCCCCEEEHHHHHHHHHHHCHHHHCCCCEEEEECCCHHHHHHHHHHHH
KDKDINYSAPLYVTAEFINNETQEIKSQTVFIGDFPMMTDKGTFIVNGTERVVVSQLVRS
CCCCCCCCCCEEEEHHHHCCHHHHHCCCEEEEECCCEEECCCEEEECCCHHHHHHHHHHC
PGVYFDQTIDKSTERPLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALG
CCCEEEHHHCCHHCCCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHC
WTTEQITERFGFSEIMMSTLESDGVSNTDEALLEIYRKQRPGEQPTRDLAQSLLDNSFFR
CCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
AKRYDLAKVGRYKVNRKLGLGGDNEGLMTLTEEDIATTLEYLVRLHAGETTMTSPTGEVI
HHHCCHHHHCCEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEECCCCCCEE
PVETDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRERMTTQDAESITPTSLINVRPV
ECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHH
SAAIREFFGTSQLSQFMDQNNSLSGLTHKRRLSALGPGGLSRERAGIEVRDVHASHYGRM
HHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECHHHCCCC
CPIETPEGPNIGLIGSLASYARVNAFGFIETPYRKVENGVLTDQIDYLTADEEDRFVVAQ
CCCCCCCCCCEEEHHHHHHHHHHCEEEEECCCHHHHHCCCCCCCCCEEECCCCCCEEEEE
ANVEHDADGKITADSVTVRVKNGDIQVVAPESVDYLDVSPRQMVSVATAMIPFLEHDDAN
CCCCCCCCCCEEECEEEEEEECCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHCCCCCC
RALMGANMQRQAVPLVRSEAPFVGTGMERAAAYDAGDLIINKKGGVVENVSADIITVMAD
CEEECCCCHHHCCCHHHCCCCCCCCCHHHHHCCCCCCEEEECCCCEEECCCCCEEEEEEC
DGTRETYILRKFERTNQGTCYNQTPLVNIGDRVEAGQVLADGPGTHNGEMSLGRNLLVAF
CCCCCCHHHHHHHCCCCCCEECCCCEEECCCCCCCCCEEECCCCCCCCCHHCCCCEEEEE
MPWEGHNYEDAIILNQRVVEEDILTSIHIEEHEIDARDTKLGPEEITREIPNVSEDVLKD
ECCCCCCCCCEEEECHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
LDERGIVRIGADVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSMKVPHGE
HHHCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGKVIGVRRFSRDDDDDLAPGVNEMIRVYVAQKRKIQDGDKLAGRHGNKGVVGKILPQED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCC
MPFMPDGTPVDIILNTHGVPRRMNIGQVLEVHLGWLAAAGWKIDTEDPANAELLKTLPED
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHH
LYDVPAGSLTATPVFDGATNEEIAGLLGNSRPNRDGDVMVDENGKATLFDGRSGEPFPYP
HHHCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCC
VSVGYMYILKLHHLVDEKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMQAYGAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHCHH
YTLQELLTIKSDDVVGRVKVYEAIVKGENIPDPGIPESFKVLLKELQSLCLNVEVLSADG
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCC
TPMELSGSDDDEFDQAGASLGINLSRDERSDADIA
CEEECCCCCCHHHHHCCCCCCCEECCCCCCCCCCC
>Mature Secondary Structure
MVNIAGPPPREVLEGPILAVSRQTKANIPGAPERKSFAKITEPIEVPGLLDIQLNSFAWL
CCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCEEEE
IGTPEWRARQQEELGDSVRVTSGLEDILEELSPIQDYSGNMSLSLSEPRFEDMKNTIDEC
EECCHHHHHHHHHCCCCEEEHHHHHHHHHHHCHHHHCCCCEEEEECCCHHHHHHHHHHHH
KDKDINYSAPLYVTAEFINNETQEIKSQTVFIGDFPMMTDKGTFIVNGTERVVVSQLVRS
CCCCCCCCCCEEEEHHHHCCHHHHHCCCEEEEECCCEEECCCEEEECCCHHHHHHHHHHC
PGVYFDQTIDKSTERPLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALG
CCCEEEHHHCCHHCCCCCEEEEECCCCCEEEEECCCCCCEEEEECCCCCCHHHHHHHHHC
WTTEQITERFGFSEIMMSTLESDGVSNTDEALLEIYRKQRPGEQPTRDLAQSLLDNSFFR
CCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
AKRYDLAKVGRYKVNRKLGLGGDNEGLMTLTEEDIATTLEYLVRLHAGETTMTSPTGEVI
HHHCCHHHHCCEEECCEECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEECCCCCCEE
PVETDDIDHFGNRRLRTVGELIQNQVRVGLSRMERVVRERMTTQDAESITPTSLINVRPV
ECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHH
SAAIREFFGTSQLSQFMDQNNSLSGLTHKRRLSALGPGGLSRERAGIEVRDVHASHYGRM
HHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECHHHCCCC
CPIETPEGPNIGLIGSLASYARVNAFGFIETPYRKVENGVLTDQIDYLTADEEDRFVVAQ
CCCCCCCCCCEEEHHHHHHHHHHCEEEEECCCHHHHHCCCCCCCCCEEECCCCCCEEEEE
ANVEHDADGKITADSVTVRVKNGDIQVVAPESVDYLDVSPRQMVSVATAMIPFLEHDDAN
CCCCCCCCCCEEECEEEEEEECCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHCCCCCC
RALMGANMQRQAVPLVRSEAPFVGTGMERAAAYDAGDLIINKKGGVVENVSADIITVMAD
CEEECCCCHHHCCCHHHCCCCCCCCCHHHHHCCCCCCEEEECCCCEEECCCCCEEEEEEC
DGTRETYILRKFERTNQGTCYNQTPLVNIGDRVEAGQVLADGPGTHNGEMSLGRNLLVAF
CCCCCCHHHHHHHCCCCCCEECCCCEEECCCCCCCCCEEECCCCCCCCCHHCCCCEEEEE
MPWEGHNYEDAIILNQRVVEEDILTSIHIEEHEIDARDTKLGPEEITREIPNVSEDVLKD
ECCCCCCCCCEEEECHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
LDERGIVRIGADVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSMKVPHGE
HHHCCEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGKVIGVRRFSRDDDDDLAPGVNEMIRVYVAQKRKIQDGDKLAGRHGNKGVVGKILPQED
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEEECCCCC
MPFMPDGTPVDIILNTHGVPRRMNIGQVLEVHLGWLAAAGWKIDTEDPANAELLKTLPED
CCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHH
LYDVPAGSLTATPVFDGATNEEIAGLLGNSRPNRDGDVMVDENGKATLFDGRSGEPFPYP
HHHCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCC
VSVGYMYILKLHHLVDEKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWAMQAYGAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEHHHCHH
YTLQELLTIKSDDVVGRVKVYEAIVKGENIPDPGIPESFKVLLKELQSLCLNVEVLSADG
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCC
TPMELSGSDDDEFDQAGASLGINLSRDERSDADIA
CEEECCCCCCHHHHHCCCCCCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910