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The map label for this gene is kdpD [H]

Identifier: 38232908

GI number: 38232908

Start: 255150

End: 255947

Strand: Reverse

Name: kdpD [H]

Synonym: DIP0287

Alternate gene names: 38232908

Gene position: 255947-255150 (Counterclockwise)

Preceding gene: 38232909

Following gene: 38232907

Centisome position: 10.28

GC content: 58.02

Gene sequence:

>798_bases
ATGTTTGCTGCTCTGGTTCTCACTGCGTGTGGGTCTGCGTGTGCTGCGTCGTTGGTTACGGCTGCGGTGGTGCGCCGGCG
CGGCTGCGATCAGGGGTCGACGATAACGGATGAGCAGATTTTGGCTCATGAGATTCGCACGCCGTTGTCGTTGATTAAGG
GGGCTGCGGAGTTGCTGGGCCAGGAGTCCGATCCGCACAAGTGTGAGCGGCTCGTGGCTACTATTGGGGCGAATTCGACG
CGTGCGATTGAGGTGGCGGAGTCGTTTTTGTTGCAGGCAAAGCTCAATAGTGGTTCGGTGAAGTTGCAGGTGTCGCCGTG
CGATGTGCGGGGGTTGGTGCGTAGTACGGCGCAGGAGCTGCGGGCGATGAGCGAGGTTCCGATTGTGGTGGATGATCCTG
GCGATCCGTTGGTGATTGATGGGGATGCGCAGTTGTTGCGGCATGCGTTGTGGAATGTGTTGAATAATGCGGCACGTTAT
GCGGGCTCGGATAGCGATATTGTGGTGGGGGTTGAGGAGAGCGCTACTGGGGTGATTGTGACGGTGGCGGATTATGGGCC
GGGGATGACGTCGCGTCAGCGTCGGGATATGTTTGTGCCCTTTGCCCAGTTCGGCCAGGCCCATGCACAGGGCCATACAC
AGACCCAGAGCACAGCTGCGGTTCCGTCTGGTGCGGGGTTGGGGATGGCGATTACGCAGAAGATTGTGCAGTTGCATCGT
GGTTCGGTGTTGGTGGATTCTATTGCGGATCATGGAACGTCGGTGTTGATTACTCTTCCTAGGACTTACTATGCATAG

Upstream 100 bases:

>100_bases
AACCGCAGGATGGCCTTTCAAAAATCGGCCTTAGGGTACAAAAATTGCTCATTTCCTTTAACCAAAACATTTCGGGTGAG
CCACGGTAGTGTTATCTAGT

Downstream 100 bases:

>100_bases
GCTTCGTGTTCTTGTTGTTGATGATGAGCCGCAGATGGTTCAGATTATTTCTTATGCTTTGGAGTTGGAGGGCTGGGAGG
TGTTGTCGGCTTCCTCAGCG

Product: two-component sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MFAALVLTACGSACAASLVTAAVVRRRGCDQGSTITDEQILAHEIRTPLSLIKGAAELLGQESDPHKCERLVATIGANST
RAIEVAESFLLQAKLNSGSVKLQVSPCDVRGLVRSTAQELRAMSEVPIVVDDPGDPLVIDGDAQLLRHALWNVLNNAARY
AGSDSDIVVGVEESATGVIVTVADYGPGMTSRQRRDMFVPFAQFGQAHAQGHTQTQSTAAVPSGAGLGMAITQKIVQLHR
GSVLVDSIADHGTSVLITLPRTYYA

Sequences:

>Translated_265_residues
MFAALVLTACGSACAASLVTAAVVRRRGCDQGSTITDEQILAHEIRTPLSLIKGAAELLGQESDPHKCERLVATIGANST
RAIEVAESFLLQAKLNSGSVKLQVSPCDVRGLVRSTAQELRAMSEVPIVVDDPGDPLVIDGDAQLLRHALWNVLNNAARY
AGSDSDIVVGVEESATGVIVTVADYGPGMTSRQRRDMFVPFAQFGQAHAQGHTQTQSTAAVPSGAGLGMAITQKIVQLHR
GSVLVDSIADHGTSVLITLPRTYYA
>Mature_265_residues
MFAALVLTACGSACAASLVTAAVVRRRGCDQGSTITDEQILAHEIRTPLSLIKGAAELLGQESDPHKCERLVATIGANST
RAIEVAESFLLQAKLNSGSVKLQVSPCDVRGLVRSTAQELRAMSEVPIVVDDPGDPLVIDGDAQLLRHALWNVLNNAARY
AGSDSDIVVGVEESATGVIVTVADYGPGMTSRQRRDMFVPFAQFGQAHAQGHTQTQSTAAVPSGAGLGMAITQKIVQLHR
GSVLVDSIADHGTSVLITLPRTYYA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=225, Percent_Identity=29.3333333333333, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=26.3392857142857, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=255, Percent_Identity=27.843137254902, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=24.5535714285714, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=25.3112033195021, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790551, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=25.7777777777778, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=23.5807860262009, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786600, Length=222, Percent_Identity=22.972972972973, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 27885; Mature: 27885

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAALVLTACGSACAASLVTAAVVRRRGCDQGSTITDEQILAHEIRTPLSLIKGAAELLG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
QESDPHKCERLVATIGANSTRAIEVAESFLLQAKLNSGSVKLQVSPCDVRGLVRSTAQEL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHH
RAMSEVPIVVDDPGDPLVIDGDAQLLRHALWNVLNNAARYAGSDSDIVVGVEESATGVIV
HHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
TVADYGPGMTSRQRRDMFVPFAQFGQAHAQGHTQTQSTAAVPSGAGLGMAITQKIVQLHR
EEECCCCCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GSVLVDSIADHGTSVLITLPRTYYA
CCEEEHHHHCCCCEEEEECCHHHCC
>Mature Secondary Structure
MFAALVLTACGSACAASLVTAAVVRRRGCDQGSTITDEQILAHEIRTPLSLIKGAAELLG
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
QESDPHKCERLVATIGANSTRAIEVAESFLLQAKLNSGSVKLQVSPCDVRGLVRSTAQEL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHHHHH
RAMSEVPIVVDDPGDPLVIDGDAQLLRHALWNVLNNAARYAGSDSDIVVGVEESATGVIV
HHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEE
TVADYGPGMTSRQRRDMFVPFAQFGQAHAQGHTQTQSTAAVPSGAGLGMAITQKIVQLHR
EEECCCCCCCCCCCCCCCCCHHHHCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GSVLVDSIADHGTSVLITLPRTYYA
CCEEEHHHHCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]