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The map label for this gene is asd [H]

Identifier: 38232900

GI number: 38232900

Start: 246016

End: 247047

Strand: Direct

Name: asd [H]

Synonym: DIP0279

Alternate gene names: 38232900

Gene position: 246016-247047 (Clockwise)

Preceding gene: 38232899

Following gene: 38232902

Centisome position: 9.89

GC content: 59.21

Gene sequence:

>1032_bases
ATGACCACTGTTGCAGTTGTCGGGGCCACCGGCCAAGTCGGCCGCGTAATGCGTTCGATCTTGGAAGAGCGTGACTTCCC
ACTGGACACCATCCGATTCTTCGCCTCTGCGCGTTCCGCCGGAACCACCTTGCCCTACAAGGGTCAAGAAATAGAGGTTG
AAGACCTAGCTCTGCAAATCGAAGAAAGCCTCGCGGGTATCGACATCGCGTTGTTCTCCGCAGGCGGTAGCACCTCCAAG
CAGTACGCACCCCTGTTCGCCGCAGCTGGCGCAACCGTGGTGGACAACTCCTCTGCGTGGCGCAAAGACGACGAGGTGCC
ACTGATCGTTTCTGAGGTCAACCCAGACGCAAAGAACGACGTGGTCAAGGGCATTATCGCGAACCCGAACTGCACCACCA
TGGCAATCATGCCTGTGGTCAAGGCGCTTCACGACGCCGCTGGCGTGACCAAGCTGCATGTCTCCTCCTACCAGGCGGTA
TCCGGCTCCGGGCTCGCCGGTGTAGAAACCCTGATCAAGCAGGTTGCTGAGATCGGTGACCGCGCCGTAGAGCTCGTTCA
CGACGGCTCCCTGCTCGCACCGGAAGACATGGGCCCTTACGTGGCACCCATCGCGTTCAACGCCCTGCCATTCGCTGGCA
ACCTTGTGGAAGACGGCACTGAGGAAACCGACGAAGAACAGAAGCTGCGCAACGAGTCCCGCAAGATCCTCGGCCTGCCA
GACCTGAAGGTTGCCGGTACTTGTGTTCGTGTGCCTGTCTTTACCGGTCACACCATGGTGGTGCACGCTGAGTTCAACAA
CGCCATCACCCCAGAACAGGCACGCGAGGTGCTTGGAAACGCTGCAGGTGTTGACGTTGTGGACGTTCCAACGCCACTGG
CTGCTGCGGGCGTAGACAACTCCCTTGTGGGCCGTATCCGTCAGGATCAGACCGTAGACGACAACAAGGGCCTCGTCTTT
GTTGTCTCCGGCGACAATCTACGCAAGGGCGCTGCACTCAACGCCATCCAGATTGCTGAGCTTTTGGTCTAA

Upstream 100 bases:

>100_bases
TTTATAGTGCGCGTTTTTGTGTGTAGGCTACTGTATTCAGTAGAGGTGTCGCACAATGAAATGCAATACCCTTCGGAGCG
AAAGAAAGGGAAATTTGACC

Downstream 100 bases:

>100_bases
TAGCGGTTAGCCCGCTGCCTCGTTGGTGTCGGTTTCCGTGGCTGCGGCTGCGACGATATCAGCGCGGGCGCGGGCCACGC
GGGAACGAATCGTGCCGATG

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTTVAVVGATGQVGRVMRSILEERDFPLDTIRFFASARSAGTTLPYKGQEIEVEDLALQIEESLAGIDIALFSAGGSTSK
QYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPDAKNDVVKGIIANPNCTTMAIMPVVKALHDAAGVTKLHVSSYQAV
SGSGLAGVETLIKQVAEIGDRAVELVHDGSLLAPEDMGPYVAPIAFNALPFAGNLVEDGTEETDEEQKLRNESRKILGLP
DLKVAGTCVRVPVFTGHTMVVHAEFNNAITPEQAREVLGNAAGVDVVDVPTPLAAAGVDNSLVGRIRQDQTVDDNKGLVF
VVSGDNLRKGAALNAIQIAELLV

Sequences:

>Translated_343_residues
MTTVAVVGATGQVGRVMRSILEERDFPLDTIRFFASARSAGTTLPYKGQEIEVEDLALQIEESLAGIDIALFSAGGSTSK
QYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPDAKNDVVKGIIANPNCTTMAIMPVVKALHDAAGVTKLHVSSYQAV
SGSGLAGVETLIKQVAEIGDRAVELVHDGSLLAPEDMGPYVAPIAFNALPFAGNLVEDGTEETDEEQKLRNESRKILGLP
DLKVAGTCVRVPVFTGHTMVVHAEFNNAITPEQAREVLGNAAGVDVVDVPTPLAAAGVDNSLVGRIRQDQTVDDNKGLVF
VVSGDNLRKGAALNAIQIAELLV
>Mature_342_residues
TTVAVVGATGQVGRVMRSILEERDFPLDTIRFFASARSAGTTLPYKGQEIEVEDLALQIEESLAGIDIALFSAGGSTSKQ
YAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPDAKNDVVKGIIANPNCTTMAIMPVVKALHDAAGVTKLHVSSYQAVS
GSGLAGVETLIKQVAEIGDRAVELVHDGSLLAPEDMGPYVAPIAFNALPFAGNLVEDGTEETDEEQKLRNESRKILGLPD
LKVAGTCVRVPVFTGHTMVVHAEFNNAITPEQAREVLGNAAGVDVVDVPTPLAAAGVDNSLVGRIRQDQTVDDNKGLVFV
VSGDNLRKGAALNAIQIAELLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=351, Percent_Identity=31.9088319088319, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789841, Length=372, Percent_Identity=26.3440860215054, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36048; Mature: 35917

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVAVVGATGQVGRVMRSILEERDFPLDTIRFFASARSAGTTLPYKGQEIEVEDLALQI
CCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHH
EESLAGIDIALFSAGGSTSKQYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPDAKND
HHHHCCEEEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHHHH
VVKGIIANPNCTTMAIMPVVKALHDAAGVTKLHVSSYQAVSGSGLAGVETLIKQVAEIGD
HHEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RAVELVHDGSLLAPEDMGPYVAPIAFNALPFAGNLVEDGTEETDEEQKLRNESRKILGLP
HHEEHEECCCEECCCCCCCEEEHHEECCCCCCCCHHCCCCCCCCHHHHHHHHCCEEECCC
DLKVAGTCVRVPVFTGHTMVVHAEFNNAITPEQAREVLGNAAGVDVVDVPTPLAAAGVDN
CCCCCCEEEEEEEEECCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCHHHCCCCH
SLVGRIRQDQTVDDNKGLVFVVSGDNLRKGAALNAIQIAELLV
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHC
>Mature Secondary Structure 
TTVAVVGATGQVGRVMRSILEERDFPLDTIRFFASARSAGTTLPYKGQEIEVEDLALQI
CEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHH
EESLAGIDIALFSAGGSTSKQYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPDAKND
HHHHCCEEEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCCCCCCCCEEEEECCCCHHHH
VVKGIIANPNCTTMAIMPVVKALHDAAGVTKLHVSSYQAVSGSGLAGVETLIKQVAEIGD
HHEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RAVELVHDGSLLAPEDMGPYVAPIAFNALPFAGNLVEDGTEETDEEQKLRNESRKILGLP
HHEEHEECCCEECCCCCCCEEEHHEECCCCCCCCHHCCCCCCCCHHHHHHHHCCEEECCC
DLKVAGTCVRVPVFTGHTMVVHAEFNNAITPEQAREVLGNAAGVDVVDVPTPLAAAGVDN
CCCCCCEEEEEEEEECCEEEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCCHHHCCCCH
SLVGRIRQDQTVDDNKGLVFVVSGDNLRKGAALNAIQIAELLV
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8100567 [H]