Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 38232870

GI number: 38232870

Start: 209792

End: 210235

Strand: Direct

Name: tadA [H]

Synonym: DIP0247

Alternate gene names: 38232870

Gene position: 209792-210235 (Clockwise)

Preceding gene: 38232869

Following gene: 38232871

Centisome position: 8.43

GC content: 65.77

Gene sequence:

>444_bases
ATGATGCGCGAAGCCATCACCCTCGCACACACCACACCGCCTGCCGACATCCCCGTCGGAGCCATCATCTACGGCCCCGA
CGGCACCATCCTCGGCCGCGGCACCAACCGCCGCGAAACCGACCACAACCCCCTCGGCCACGCCGAAATCATGGCCATCA
CCCAAGCCTGCACCCAGCGTGGCGACGGCTGGCGCCTTACCGACTGCACCCTCGCAGTTACCCTCGAACCCTGCACCATG
TGCGCCGGAGCCCTCGTCGGCTCCCGAATCGGACACATCATCTTTGGAGCCTACGAACCCAAAACCGGCGCCTGCGGCTC
CGCCTTCGACGTAGTCCGCGACCCCGCCGTCCTCCACACCGTGCAAGTCCGCGGCGGCATCCTCGAAGCCGAATGCGCCG
AACTCATGACAAACTTCTTCGGAGGACTGCGCACCGAAGCATGA

Upstream 100 bases:

>100_bases
AACAACTCCAACGCATAGCCGAAGAACTCGGATTCGACGACGAACTCGAACAAGCCCTATGACACTGCCCCCGCAGCACA
GCGTGGTACGAGCCGAAGCC

Downstream 100 bases:

>100_bases
GCGAGGCTGGTTTGCGTTGCTGCTGCGATATTCGCTATTCTGGTTCGCGGTAGCGTGTCCGAGCGGCCGAAGGTGTTCGC
CTCGAAAGCGAATGTTGGGT

Product: putative cytosine deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MMREAITLAHTTPPADIPVGAIIYGPDGTILGRGTNRRETDHNPLGHAEIMAITQACTQRGDGWRLTDCTLAVTLEPCTM
CAGALVGSRIGHIIFGAYEPKTGACGSAFDVVRDPAVLHTVQVRGGILEAECAELMTNFFGGLRTEA

Sequences:

>Translated_147_residues
MMREAITLAHTTPPADIPVGAIIYGPDGTILGRGTNRRETDHNPLGHAEIMAITQACTQRGDGWRLTDCTLAVTLEPCTM
CAGALVGSRIGHIIFGAYEPKTGACGSAFDVVRDPAVLHTVQVRGGILEAECAELMTNFFGGLRTEA
>Mature_147_residues
MMREAITLAHTTPPADIPVGAIIYGPDGTILGRGTNRRETDHNPLGHAEIMAITQACTQRGDGWRLTDCTLAVTLEPCTM
CAGALVGSRIGHIIFGAYEPKTGACGSAFDVVRDPAVLHTVQVRGGILEAECAELMTNFFGGLRTEA

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=46.5753424657534, Blast_Score=125, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17541138, Length=149, Percent_Identity=31.5436241610738, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 15551; Mature: 15551

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMREAITLAHTTPPADIPVGAIIYGPDGTILGRGTNRRETDHNPLGHAEIMAITQACTQR
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
GDGWRLTDCTLAVTLEPCTMCAGALVGSRIGHIIFGAYEPKTGACGSAFDVVRDPAVLHT
CCCEEEEEEEEEEEECHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHCCCHHEEE
VQVRGGILEAECAELMTNFFGGLRTEA
EECCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMREAITLAHTTPPADIPVGAIIYGPDGTILGRGTNRRETDHNPLGHAEIMAITQACTQR
CCCCEEEEEECCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCC
GDGWRLTDCTLAVTLEPCTMCAGALVGSRIGHIIFGAYEPKTGACGSAFDVVRDPAVLHT
CCCEEEEEEEEEEEECHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCHHHHHCCCHHEEE
VQVRGGILEAECAELMTNFFGGLRTEA
EECCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]