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The map label for this gene is sdcS [H]

Identifier: 38232804

GI number: 38232804

Start: 152426

End: 154000

Strand: Direct

Name: sdcS [H]

Synonym: DIP0179

Alternate gene names: 38232804

Gene position: 152426-154000 (Clockwise)

Preceding gene: 38232801

Following gene: 38232805

Centisome position: 6.12

GC content: 53.08

Gene sequence:

>1575_bases
GTGAGTACACCGATTACACATGAGTCTTCGTCTCATGCTCTTGCTGAGGATGCAGAGGTCCATGGGAAGAATGAGAACCG
CCGGCAGTTTACGGGTTTGTTCGCTGGTTTGATTCTTGCCGTTTTGATTTATTTGGTGTTCCCTGAGTCGTCTGTGGACA
TGGTTCAGGGTGTGGATCCGGATGGGGAGTATAGCTATAACGCGTTGCGTATTACTGCTGCTATTGCGGTGTTGATGGGT
GCGTGGTGGATGACGGAGGCTATTCCGTTGGCTGCGACGGCGTTGGTGCCGTTGGTGGCGTTCCCTGTTCTTCAGGTGAT
TCCGTTTGCGAAGATTTCTGCGCCGTATGCGTCGCCGACGATTTTCCTTTTTATGGGTGGTTTTATTTTGGCGTTGGGTA
TGCAGCGTTGGAATTTGCATCGTCGGTTGGCGTTGAGTGTGGTGTTGTTGGTTGGTACGAAGCCTAAGCAGTTGATTGCT
GGTTTTATGCTGGCTACGGGCTTTTTGTCGATGTGGGTGTCTAATACTGCGACGGCTGTTGTGATGCTTCCGATTGGTGT
TTCGGTGTTGCAGCTGACTGCTGAGTCGGTGGGTGGCATGAAGGCGCAGAAGAAGTTTGCGACTGCGTTGATGTTGGCGA
TTGCGTATTCGGCGTCGATTGGTTCTTTGGGCACGATTATTGGTACGCCTCCTAATGCGTTGATGGTGGCGTATATGGCG
GAGAATCATGACATCCATATTGGTTTTGGTACGTGGATGCTGGTTGGTGTGCCGTTGGCGATTGTTTATATGGCGATTGC
TTGGTTGGTGCTGGTGTCTGTGTTTAAGCCTGAGGTGGATTCGATTCCTGGTGGCCGCGAGATGATTAAGTCGGAGTTGG
CCAAGATGGGGTCGATGAAGTTCGGTGAGGCTGCTACTGCGGTGATTTTTACGGGTGCGGCGTTGTCATGGGTGTTTGTT
CCGCTGCTTATCGACGTTTTCCAGTGGAAGGTTGAGATTGCGGATGCGGCTATTGGTCTGATTGCTTCGATGTTGCTGTT
TATGATCCCTGCGGATCGTAAGACTGGTGTGCGTTTGACGGATTGGAAGACGGCGAATGAGTTGCCGTGGGATGTGTTGT
TGCTGTTCGGCGGCGGTTTGGCATTGTCTAAGATGTTCTCTGATTCTGGCTTGTCCTTGTGGATTGGTGAGATCGCCAAG
GGCCTGGTCTCGCTGCCGCTGATTTTGCTGATCGCTGCGATTGCGGCGCTGGTTTTGCTGTTGACGGAGTTCACGTCGAA
TACTGCGACGGCTGCGACGTTCTTGCCGATCATGGCCGGTGTGGCTGTGGGTATCGGTCTGAACGCTAATGGTGACCAGA
ACATCTTGTTGCTGACCATCCCAGTGGCGCTGTCGGCTACCTGTGCGTTCATGCTGCCGGTTGCGACGCCTCCGAATGCG
ATCGCTTATGGCTCCGGCCACGTGCGCATTGGCGACATGGTCAAGGGCGGAGTGTGGCTCAATCTGATCGGCGTGGTGCT
CGTAACCCTTGCGACATACTTCCTTGCCATCCCAGTATTCAACATCGTCCTCTAG

Upstream 100 bases:

>100_bases
CAATGATCGCACGTTTCGGGGGTGATGGTTGTATTTTGTTCGTGTAGGCGAACCTTGGAGTTTGCACGCCCCTCTTATTT
TCTATTGAAGGATTTCTTTT

Downstream 100 bases:

>100_bases
TGCGCTGACCTCACGATTTGCCAGTTCTTGTTGTGGCAGTGTATTGTTCTAACACGTTGCACCGCAACAACAAGCTGCGC
CCGTAGCTCAACGGATAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSTPITHESSSHALAEDAEVHGKNENRRQFTGLFAGLILAVLIYLVFPESSVDMVQGVDPDGEYSYNALRITAAIAVLMG
AWWMTEAIPLAATALVPLVAFPVLQVIPFAKISAPYASPTIFLFMGGFILALGMQRWNLHRRLALSVVLLVGTKPKQLIA
GFMLATGFLSMWVSNTATAVVMLPIGVSVLQLTAESVGGMKAQKKFATALMLAIAYSASIGSLGTIIGTPPNALMVAYMA
ENHDIHIGFGTWMLVGVPLAIVYMAIAWLVLVSVFKPEVDSIPGGREMIKSELAKMGSMKFGEAATAVIFTGAALSWVFV
PLLIDVFQWKVEIADAAIGLIASMLLFMIPADRKTGVRLTDWKTANELPWDVLLLFGGGLALSKMFSDSGLSLWIGEIAK
GLVSLPLILLIAAIAALVLLLTEFTSNTATAATFLPIMAGVAVGIGLNANGDQNILLLTIPVALSATCAFMLPVATPPNA
IAYGSGHVRIGDMVKGGVWLNLIGVVLVTLATYFLAIPVFNIVL

Sequences:

>Translated_524_residues
MSTPITHESSSHALAEDAEVHGKNENRRQFTGLFAGLILAVLIYLVFPESSVDMVQGVDPDGEYSYNALRITAAIAVLMG
AWWMTEAIPLAATALVPLVAFPVLQVIPFAKISAPYASPTIFLFMGGFILALGMQRWNLHRRLALSVVLLVGTKPKQLIA
GFMLATGFLSMWVSNTATAVVMLPIGVSVLQLTAESVGGMKAQKKFATALMLAIAYSASIGSLGTIIGTPPNALMVAYMA
ENHDIHIGFGTWMLVGVPLAIVYMAIAWLVLVSVFKPEVDSIPGGREMIKSELAKMGSMKFGEAATAVIFTGAALSWVFV
PLLIDVFQWKVEIADAAIGLIASMLLFMIPADRKTGVRLTDWKTANELPWDVLLLFGGGLALSKMFSDSGLSLWIGEIAK
GLVSLPLILLIAAIAALVLLLTEFTSNTATAATFLPIMAGVAVGIGLNANGDQNILLLTIPVALSATCAFMLPVATPPNA
IAYGSGHVRIGDMVKGGVWLNLIGVVLVTLATYFLAIPVFNIVL
>Mature_523_residues
STPITHESSSHALAEDAEVHGKNENRRQFTGLFAGLILAVLIYLVFPESSVDMVQGVDPDGEYSYNALRITAAIAVLMGA
WWMTEAIPLAATALVPLVAFPVLQVIPFAKISAPYASPTIFLFMGGFILALGMQRWNLHRRLALSVVLLVGTKPKQLIAG
FMLATGFLSMWVSNTATAVVMLPIGVSVLQLTAESVGGMKAQKKFATALMLAIAYSASIGSLGTIIGTPPNALMVAYMAE
NHDIHIGFGTWMLVGVPLAIVYMAIAWLVLVSVFKPEVDSIPGGREMIKSELAKMGSMKFGEAATAVIFTGAALSWVFVP
LLIDVFQWKVEIADAAIGLIASMLLFMIPADRKTGVRLTDWKTANELPWDVLLLFGGGLALSKMFSDSGLSLWIGEIAKG
LVSLPLILLIAAIAALVLLLTEFTSNTATAATFLPIMAGVAVGIGLNANGDQNILLLTIPVALSATCAFMLPVATPPNAI
AYGSGHVRIGDMVKGGVWLNLIGVVLVTLATYFLAIPVFNIVL

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=513, Percent_Identity=35.2826510721248, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI4506979, Length=530, Percent_Identity=32.2641509433962, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI301069346, Length=493, Percent_Identity=32.657200811359, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI19923838, Length=543, Percent_Identity=31.8600368324125, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI225637549, Length=579, Percent_Identity=29.8791018998273, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI225637552, Length=497, Percent_Identity=31.3883299798793, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI219802232, Length=454, Percent_Identity=32.5991189427313, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI58761541, Length=368, Percent_Identity=31.5217391304348, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI31377715, Length=368, Percent_Identity=31.5217391304348, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI301069353, Length=368, Percent_Identity=31.5217391304348, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI31795546, Length=355, Percent_Identity=32.6760563380282, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI301069349, Length=363, Percent_Identity=30.0275482093664, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1786829, Length=404, Percent_Identity=25, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789444, Length=414, Percent_Identity=23.9130434782609, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71988385, Length=455, Percent_Identity=36.7032967032967, Blast_Score=248, Evalue=6e-66,
Organism=Caenorhabditis elegans, GI32565804, Length=460, Percent_Identity=37.1739130434783, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17551790, Length=544, Percent_Identity=29.0441176470588, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI71989118, Length=512, Percent_Identity=31.8359375, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32564681, Length=502, Percent_Identity=28.8844621513944, Blast_Score=204, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6322263, Length=424, Percent_Identity=28.7735849056604, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324340, Length=448, Percent_Identity=26.3392857142857, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319885, Length=451, Percent_Identity=27.0509977827051, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI281366409, Length=487, Percent_Identity=30.8008213552361, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI17737623, Length=487, Percent_Identity=30.8008213552361, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24666468, Length=487, Percent_Identity=30.8008213552361, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI45551633, Length=487, Percent_Identity=30.8008213552361, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI281362116, Length=473, Percent_Identity=28.7526427061311, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281362114, Length=473, Percent_Identity=28.5412262156448, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281362112, Length=473, Percent_Identity=28.5412262156448, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI78706796, Length=482, Percent_Identity=27.3858921161826, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI78706798, Length=482, Percent_Identity=27.3858921161826, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 55556; Mature: 55425

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPITHESSSHALAEDAEVHGKNENRRQFTGLFAGLILAVLIYLVFPESSVDMVQGVDP
CCCCCCCCCCCCCHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DGEYSYNALRITAAIAVLMGAWWMTEAIPLAATALVPLVAFPVLQVIPFAKISAPYASPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCH
IFLFMGGFILALGMQRWNLHRRLALSVVLLVGTKPKQLIAGFMLATGFLSMWVSNTATAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VMLPIGVSVLQLTAESVGGMKAQKKFATALMLAIAYSASIGSLGTIIGTPPNALMVAYMA
EEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
ENHDIHIGFGTWMLVGVPLAIVYMAIAWLVLVSVFKPEVDSIPGGREMIKSELAKMGSMK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
FGEAATAVIFTGAALSWVFVPLLIDVFQWKVEIADAAIGLIASMLLFMIPADRKTGVRLT
CCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
DWKTANELPWDVLLLFGGGLALSKMFSDSGLSLWIGEIAKGLVSLPLILLIAAIAALVLL
CCCCCCCCCHHHHHHHCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LTEFTSNTATAATFLPIMAGVAVGIGLNANGDQNILLLTIPVALSATCAFMLPVATPPNA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHEEECCCCCCC
IAYGSGHVRIGDMVKGGVWLNLIGVVLVTLATYFLAIPVFNIVL
EEECCCCEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STPITHESSSHALAEDAEVHGKNENRRQFTGLFAGLILAVLIYLVFPESSVDMVQGVDP
CCCCCCCCCCCCHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DGEYSYNALRITAAIAVLMGAWWMTEAIPLAATALVPLVAFPVLQVIPFAKISAPYASPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCH
IFLFMGGFILALGMQRWNLHRRLALSVVLLVGTKPKQLIAGFMLATGFLSMWVSNTATAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VMLPIGVSVLQLTAESVGGMKAQKKFATALMLAIAYSASIGSLGTIIGTPPNALMVAYMA
EEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
ENHDIHIGFGTWMLVGVPLAIVYMAIAWLVLVSVFKPEVDSIPGGREMIKSELAKMGSMK
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
FGEAATAVIFTGAALSWVFVPLLIDVFQWKVEIADAAIGLIASMLLFMIPADRKTGVRLT
CCCHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
DWKTANELPWDVLLLFGGGLALSKMFSDSGLSLWIGEIAKGLVSLPLILLIAAIAALVLL
CCCCCCCCCHHHHHHHCCCHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LTEFTSNTATAATFLPIMAGVAVGIGLNANGDQNILLLTIPVALSATCAFMLPVATPPNA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECHHHHHHHHHEEECCCCCCC
IAYGSGHVRIGDMVKGGVWLNLIGVVLVTLATYFLAIPVFNIVL
EEECCCCEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA