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The map label for this gene is troA [H]

Identifier: 38232798

GI number: 38232798

Start: 145272

End: 146273

Strand: Direct

Name: troA [H]

Synonym: DIP0173

Alternate gene names: 38232798

Gene position: 145272-146273 (Clockwise)

Preceding gene: 38232797

Following gene: 38232801

Centisome position: 5.84

GC content: 57.29

Gene sequence:

>1002_bases
GTGGCTGCCACAGGTCTTGTGGCAGCAGCCGGCTGCTCCACCACCGACTCCGGCACCAGCGCTTCTGGAACTTCGAGCGC
CGCCAAGAGCGACACTCTTAAGATCTTTGCTACCACCAGCTACATCGGCGACGCAGTAAAGAACATCGCCCCTGATGCAG
ACCTCACCGTCATGGTGGGCCCTGGTGGCGATCCACACACCTACCAGCCTTCCACCGCTGACCTTGAGGCAATGCAAAAT
GCGGATGCCGTGATCTGGTCAGGCCTTGGCATGGAAGCCAACATGATTGACCAGCTTCGCGGGCTTGGCGACAAACAAAT
CGCCGTAGCCGAGCAGCTTCCTGAGTCCCAGCTGTTGCCATGGGTTGAGGAAGACGAGCACGATCACGATCACGGCGACG
CCCACGAGCACGGGCACGAGGGTGAAGATGCCCACGGCCACCACCATGAGTCGCAGTGGGATCCTCACGTATGGAACTCC
ACCGACAACTGGAAGCTCGTTGTTGATCAGATCGTTAAGAAGCTCTCCGCTGCTGATTCTGCTAACGCTGACACCTACAA
GGCCAATGGTGAGAAGTACAACAAGCAGATCGACGAGGCCAAGGCTTATGTTCAGGCCAAGATTGACACGATTCCGCAGG
ATCAGCGCACCCTCGTCTCGGGTCACGACGCTTTCCGTTACTTTGGCAAGCAGTTCGGCCTTGAGGTGAAGGCCACCGAC
TTTGTCACCTCTGATGCTGAGCGTTCTGCAAACGAGCTGGAAGACTTAGCCACCTTCATCGTGGAGCACCACGTCCCAGT
GATCTTCCAGGATGCTTCTGCTAACCCACAGGCTGTGAAGTCCTTGGAGGAGAACGTTGCTAAGAAGGGCGGCAAGGTCA
AGGTTGTGGATAAGGAGCTCTATAGTGACTCCCTTGGTGCCGACGCCCCTGCTGATACCTACATCGGTGCCCTGAAGTAC
AACGCGGATACCATCGCGGAGGCTTTCTCCTCGACCCGCTAA

Upstream 100 bases:

>100_bases
GTTGATGGGTATCTAAGTGTGCGCTTCCTAGTGCACATGACAATCGTTGCCTATAGTGGCGGTCATGGCACATCGACTAA
TCCGTACCGCAATCGCAGCT

Downstream 100 bases:

>100_bases
AAAATCGGTCCGGTGGGCTGGGACATCTCACGAAGAGATTCCAGCCCACCGGATGTTGGCTAGTACTACATTCTGGCTTG
CAGTCTGCGGATGTGGTCGG

Product: hypothetical protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Tromp-1 [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPDADLTVMVGPGGDPHTYQPSTADLEAMQN
ADAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQLLPWVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNS
TDNWKLVVDQIVKKLSAADSANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKATD
FVTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDKELYSDSLGADAPADTYIGALKY
NADTIAEAFSSTR

Sequences:

>Translated_333_residues
MAATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPDADLTVMVGPGGDPHTYQPSTADLEAMQN
ADAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQLLPWVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNS
TDNWKLVVDQIVKKLSAADSANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKATD
FVTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDKELYSDSLGADAPADTYIGALKY
NADTIAEAFSSTR
>Mature_332_residues
AATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPDADLTVMVGPGGDPHTYQPSTADLEAMQNA
DAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQLLPWVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNST
DNWKLVVDQIVKKLSAADSANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKATDF
VTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDKELYSDSLGADAPADTYIGALKYN
ADTIAEAFSSTR

Specific function: Part of an ATP-driven transport system troABCD for zinc. Substrate-binding protein involved in the transport of zinc across the cytoplasmic membrane [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=272, Percent_Identity=24.6323529411765, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 35790; Mature: 35659

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPDADLTVMVG
CCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEC
PGGDPHTYQPSTADLEAMQNADAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQLLP
CCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHCCHHHCCC
WVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNSTDNWKLVVDQIVKKLSAADS
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
ANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKATD
CCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCEEEEHH
FVTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDKEL
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEHHH
YSDSLGADAPADTYIGALKYNADTIAEAFSSTR
HHHCCCCCCCCHHHHEEEEECHHHHHHHHHCCC
>Mature Secondary Structure 
AATGLVAAAGCSTTDSGTSASGTSSAAKSDTLKIFATTSYIGDAVKNIAPDADLTVMVG
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEC
PGGDPHTYQPSTADLEAMQNADAVIWSGLGMEANMIDQLRGLGDKQIAVAEQLPESQLLP
CCCCCCCCCCCCHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHCCHHHCCC
WVEEDEHDHDHGDAHEHGHEGEDAHGHHHESQWDPHVWNSTDNWKLVVDQIVKKLSAADS
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
ANADTYKANGEKYNKQIDEAKAYVQAKIDTIPQDQRTLVSGHDAFRYFGKQFGLEVKATD
CCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHCCEEEEHH
FVTSDAERSANELEDLATFIVEHHVPVIFQDASANPQAVKSLEENVAKKGGKVKVVDKEL
HCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEEHHH
YSDSLGADAPADTYIGALKYNADTIAEAFSSTR
HHHCCCCCCCCHHHHEEEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7768866; 9332349; 9665876; 10400603; 10404217 [H]