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The map label for this gene is irp6B [C]

Identifier: 38232738

GI number: 38232738

Start: 89229

End: 90272

Strand: Direct

Name: irp6B [C]

Synonym: DIP0109

Alternate gene names: 38232738

Gene position: 89229-90272 (Clockwise)

Preceding gene: 38232737

Following gene: 38232739

Centisome position: 3.59

GC content: 58.91

Gene sequence:

>1044_bases
ATGAGCAACGTAGTCGAGCAGTATCACAAGCGCTCACGACGCAAACTCTTAGCGATTGTGATTCTCACAGTGCTGGCTAT
CGCGGCATTCGTGGTGGCCACTGTGGTGGGGCCGGTGAATCTTACTCCGGCCACCATGCTGAAGGGCATTATTCAGCCCG
ATAGTGTTGATCCCACCACACGTACTGTGTTGTGGAATTTACGCCTGCCGGCGTCGGTTATGGCTGTGCTGATTGGCGCT
GCGCTGTCGCTTGCTGGTGCCCATATGCAGACCATTTTGGATAATCCGTTGGCTGAGCCCTTTACGCTGGGCATTTCGGC
GGCGGCGGCTTTCGGCGGCGCCGCGTCGATTGTTTTGGGCTGGGTGCTTATTCCGCATGCGCAGTTTAATTTGGCTGCGG
TGGCGTGGGCGTCGTCCTTGGTCGCTGTGGTGATTGTGGCTGGTGCTTCCGTATGGCGTGGTGCCGGCGCGGAATCGATG
ATTTTGCTGGGTATTGCGCTGGTGTTTTTGTTCCAGGCGCTGTTGTCGTTGATGCAGTATCGTGCCACGACTGAGGCTTT
GCAACAGATCGTCTTTTGGACGATGGGTTCGCTGCAGCGTGCAACGTGGACTGCTAATGCGATCATTGCGGTGATGTTGG
CGATTGCGATTCCGTACACGGTGGTCAACGCGTGGCGTTTGACGGCACTTCGGCTTGGCGACGCTCGCGCGGCCGCCTTG
GGCATTAACGTGACAAGGCTGCGCGTGGTCACCCTTGTGGTGGCGTCGTTGTTGGCAGCCAGCGCGGTGGCGTTTGCTGG
CATCATTGGCTTCATCGGCTTGGTTGGCCCCCACGTGGCCCGCATTTTGGTGGGCGAGGAGCAGCGCTTCTTCGCGCCGG
CGTCGATGGCAGCGGGTGCATTCCTGCTGGCTACGGCCCACGCGGTGTCTATTACGATGATCCCTGGTGTGGCGCTTCCT
ATCAGCATTATTACTGCGCTGGTGGGCGTTCCGTTCTTCGTGATCTTGGTGTTTACTCGCCGCCGCGCAATGTGGGGGTC
CTAG

Upstream 100 bases:

>100_bases
TCTGGATGCTGTGAAGGACTTCCAGGAGTTCCACAAGAAGTGGATGCCATTTGAATTCTCGGGCGTGTTCTTTGTAACCG
ACAAGGTTGAAGCTAAGTAA

Downstream 100 bases:

>100_bases
CATGAGCTTGAGTATTTCTGACCTGCGAGTCTCCTATGGTCATGGCCCGCGCATGCGCCATATTTTGAATGGTGTGAGCT
TTGGCCCAGTGCCACTAGGA

Product: membrane protein permease Irp6B

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSNVVEQYHKRSRRKLLAIVILTVLAIAAFVVATVVGPVNLTPATMLKGIIQPDSVDPTTRTVLWNLRLPASVMAVLIGA
ALSLAGAHMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVLIPHAQFNLAAVAWASSLVAVVIVAGASVWRGAGAESM
ILLGIALVFLFQALLSLMQYRATTEALQQIVFWTMGSLQRATWTANAIIAVMLAIAIPYTVVNAWRLTALRLGDARAAAL
GINVTRLRVVTLVVASLLAASAVAFAGIIGFIGLVGPHVARILVGEEQRFFAPASMAAGAFLLATAHAVSITMIPGVALP
ISIITALVGVPFFVILVFTRRRAMWGS

Sequences:

>Translated_347_residues
MSNVVEQYHKRSRRKLLAIVILTVLAIAAFVVATVVGPVNLTPATMLKGIIQPDSVDPTTRTVLWNLRLPASVMAVLIGA
ALSLAGAHMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVLIPHAQFNLAAVAWASSLVAVVIVAGASVWRGAGAESM
ILLGIALVFLFQALLSLMQYRATTEALQQIVFWTMGSLQRATWTANAIIAVMLAIAIPYTVVNAWRLTALRLGDARAAAL
GINVTRLRVVTLVVASLLAASAVAFAGIIGFIGLVGPHVARILVGEEQRFFAPASMAAGAFLLATAHAVSITMIPGVALP
ISIITALVGVPFFVILVFTRRRAMWGS
>Mature_346_residues
SNVVEQYHKRSRRKLLAIVILTVLAIAAFVVATVVGPVNLTPATMLKGIIQPDSVDPTTRTVLWNLRLPASVMAVLIGAA
LSLAGAHMQTILDNPLAEPFTLGISAAAAFGGAASIVLGWVLIPHAQFNLAAVAWASSLVAVVIVAGASVWRGAGAESMI
LLGIALVFLFQALLSLMQYRATTEALQQIVFWTMGSLQRATWTANAIIAVMLAIAIPYTVVNAWRLTALRLGDARAAALG
INVTRLRVVTLVVASLLAASAVAFAGIIGFIGLVGPHVARILVGEEQRFFAPASMAAGAFLLATAHAVSITMIPGVALPI
SIITALVGVPFFVILVFTRRRAMWGS

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=293, Percent_Identity=32.7645051194539, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790741, Length=281, Percent_Identity=37.3665480427046, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1790740, Length=280, Percent_Identity=30.7142857142857, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786805, Length=291, Percent_Identity=36.0824742268041, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786804, Length=339, Percent_Identity=29.4985250737463, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=30.0353356890459, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36370; Mature: 36239

Theoretical pI: Translated: 11.99; Mature: 11.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVVEQYHKRSRRKLLAIVILTVLAIAAFVVATVVGPVNLTPATMLKGIIQPDSVDPTT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCH
RTVLWNLRLPASVMAVLIGAALSLAGAHMQTILDNPLAEPFTLGISAAAAFGGAASIVLG
HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHH
WVLIPHAQFNLAAVAWASSLVAVVIVAGASVWRGAGAESMILLGIALVFLFQALLSLMQY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RATTEALQQIVFWTMGSLQRATWTANAIIAVMLAIAIPYTVVNAWRLTALRLGDARAAAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
GINVTRLRVVTLVVASLLAASAVAFAGIIGFIGLVGPHVARILVGEEQRFFAPASMAAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHH
FLLATAHAVSITMIPGVALPISIITALVGVPFFVILVFTRRRAMWGS
HHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNVVEQYHKRSRRKLLAIVILTVLAIAAFVVATVVGPVNLTPATMLKGIIQPDSVDPTT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCH
RTVLWNLRLPASVMAVLIGAALSLAGAHMQTILDNPLAEPFTLGISAAAAFGGAASIVLG
HEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHH
WVLIPHAQFNLAAVAWASSLVAVVIVAGASVWRGAGAESMILLGIALVFLFQALLSLMQY
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RATTEALQQIVFWTMGSLQRATWTANAIIAVMLAIAIPYTVVNAWRLTALRLGDARAAAL
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHH
GINVTRLRVVTLVVASLLAASAVAFAGIIGFIGLVGPHVARILVGEEQRFFAPASMAAGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHH
FLLATAHAVSITMIPGVALPISIITALVGVPFFVILVFTRRRAMWGS
HHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]