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The map label for this gene is dipZ [H]

Identifier: 38232731

GI number: 38232731

Start: 82259

End: 83899

Strand: Direct

Name: dipZ [H]

Synonym: DIP0101

Alternate gene names: 38232731

Gene position: 82259-83899 (Clockwise)

Preceding gene: 38232716

Following gene: 38232735

Centisome position: 3.31

GC content: 56.55

Gene sequence:

>1641_bases
ATGTTTGAATTGGCCACAATTGGATTAATCGGTGGCATTGTCACCGGTATATCCCCATGTATCTTGCCGGTTTTGCCGGT
GGTTCTCGCCGTGTCGGTGGGCCGCAGACCAACCCATGTGGTTGCTGGCCTAGCGCTCAGCTTTGCCACCATTACGCTGC
TGGGCACTGTGATTTTAAGTTCTTTGGGTCTGCCTAAAGATGTATTGCGCTGGACGGGTATCGGCCTGCTGGTGATCGTC
GGTTTGAGCATGATGATCCCTAAGCTGGGTGAGCTGGTCGAGGAACCATTTAGTCGCATTCCGCGCCCAACTTTCTTGCA
GCAAAAGGCCCGCGACAAGGGTGGCTTTATGATCGGCCTGGCCCTAGGTGCAGTGTATGTTCCCTGCGCAGGTCCTATTC
TGGCTGCTATTACCGTCGCCGGTGCGACGGGTGACATCGGTTGGCCAACGGTTGTGCTCACCGTGGCATTTGCCGTAGGT
GCGAGCCTTCCGCTGCTGGTGTTTGCGCTGGCGGGTAACAAGATGGGTGAGAAGATCGACGCGATCCGTAAGCACATGAA
GCTTGTTGGTGCGGTTATTTTGGCGCTGGCGTTGGCTATGGCGTTGAACATTCCTGAGCGTGTGCAGCGTGCGATCCCCG
ACTGGACTGCTGGTGTGCAAAAGCAGATTAGTGAAAATGACACGGTTCGTGGTGCTTTGAGTTCCGGTGGTGGCTCCTTG
GCTGCGTGCCGCGACGCCGACCCATCGATGCTGCATGACTGCGGTGAGGCACCGGAATTTGAGGGTTTGACCGGCTGGTT
TAACACGGATAAGCCTGTGTCTACGCACAGCGGCCAGGTAACGCTTGTGGACTTTTGGGCCTACGCGTGCATCAACTGCC
AGCGTGCGGGTGAGCACATCACCAAGCTTTACGACGCCTACCGCGATGCAGGCCTCCAAGTCGTAGGTGTACACGCCCCC
GAATATGGCTTTGAGCACGAGCTTGCCAACGTGAAAGATGCTGCCAAGCGCGAAGGCATTAACTACCCAGTGGCCCAAGA
CAACGACTTTGTCACATGGAAGAAGTACAACAACCGCTACTGGCCAGCCCGCTACCTAATCGACGCTCAGGGCAATGTGC
GCCACATCCACGAAGGTGAGGGTGCATACAAGGAAACTGAACAACTGGTACGCGAACTCCTGCGTGAAGCAAACCCCCAA
GTATCACTGCCGGAGCCAGTAGAAAAGGGCGTCGAAAAGCACGATGCGCAACTCACTCAGCGCCGCAACCCCGAAACCTA
CCTCGGCTACGAGCGTGCCCGCTACTTCACCAACAGCAACTACGGCCCAGGTGAACGCACCCTCGAATTCAACGCACCAA
AAGTCGGGCAATACACCCTCAGTGGAACCTGGGAGATTGCCTCCGACCACATCAACCCTGTTAAAGACGCTGCACTGTCC
GTGAACATTCACGCAGCAACCGTGCAAACAGTTGTCTCCGGCACCGGAACCCTCGAAGTGACCTACCCCGATGGCCACAC
CAAGGAATTTAAGGTGGCCGACGGCACCGTCAACGTGGTGGAACAAGACGAGCCTCTCGACGGAATCGTCACCGTGAAGC
CATCCCAAGGCGTGAGCTTCTACTCGCTAACCTTCGGCTAA

Upstream 100 bases:

>100_bases
TTTTCGCATTGTGAGCAATCCATAGCGGTGGGTGGCTCCGTATCAACTCACAGCAACGTTGAAAACCTAACCACCACTGC
GATGAGGGAGTACGTAACAG

Downstream 100 bases:

>100_bases
GCCGCATATGAAAAACGGCCAGATGAGTTGGGCACAATGTTGCTGTCCAACCCACCTGGCCGATTTTTATTAGGTGTGGC
GTTGAGCGTTGCTCTGAATA

Product: hypothetical protein

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MFELATIGLIGGIVTGISPCILPVLPVVLAVSVGRRPTHVVAGLALSFATITLLGTVILSSLGLPKDVLRWTGIGLLVIV
GLSMMIPKLGELVEEPFSRIPRPTFLQQKARDKGGFMIGLALGAVYVPCAGPILAAITVAGATGDIGWPTVVLTVAFAVG
ASLPLLVFALAGNKMGEKIDAIRKHMKLVGAVILALALAMALNIPERVQRAIPDWTAGVQKQISENDTVRGALSSGGGSL
AACRDADPSMLHDCGEAPEFEGLTGWFNTDKPVSTHSGQVTLVDFWAYACINCQRAGEHITKLYDAYRDAGLQVVGVHAP
EYGFEHELANVKDAAKREGINYPVAQDNDFVTWKKYNNRYWPARYLIDAQGNVRHIHEGEGAYKETEQLVRELLREANPQ
VSLPEPVEKGVEKHDAQLTQRRNPETYLGYERARYFTNSNYGPGERTLEFNAPKVGQYTLSGTWEIASDHINPVKDAALS
VNIHAATVQTVVSGTGTLEVTYPDGHTKEFKVADGTVNVVEQDEPLDGIVTVKPSQGVSFYSLTFG

Sequences:

>Translated_546_residues
MFELATIGLIGGIVTGISPCILPVLPVVLAVSVGRRPTHVVAGLALSFATITLLGTVILSSLGLPKDVLRWTGIGLLVIV
GLSMMIPKLGELVEEPFSRIPRPTFLQQKARDKGGFMIGLALGAVYVPCAGPILAAITVAGATGDIGWPTVVLTVAFAVG
ASLPLLVFALAGNKMGEKIDAIRKHMKLVGAVILALALAMALNIPERVQRAIPDWTAGVQKQISENDTVRGALSSGGGSL
AACRDADPSMLHDCGEAPEFEGLTGWFNTDKPVSTHSGQVTLVDFWAYACINCQRAGEHITKLYDAYRDAGLQVVGVHAP
EYGFEHELANVKDAAKREGINYPVAQDNDFVTWKKYNNRYWPARYLIDAQGNVRHIHEGEGAYKETEQLVRELLREANPQ
VSLPEPVEKGVEKHDAQLTQRRNPETYLGYERARYFTNSNYGPGERTLEFNAPKVGQYTLSGTWEIASDHINPVKDAALS
VNIHAATVQTVVSGTGTLEVTYPDGHTKEFKVADGTVNVVEQDEPLDGIVTVKPSQGVSFYSLTFG
>Mature_546_residues
MFELATIGLIGGIVTGISPCILPVLPVVLAVSVGRRPTHVVAGLALSFATITLLGTVILSSLGLPKDVLRWTGIGLLVIV
GLSMMIPKLGELVEEPFSRIPRPTFLQQKARDKGGFMIGLALGAVYVPCAGPILAAITVAGATGDIGWPTVVLTVAFAVG
ASLPLLVFALAGNKMGEKIDAIRKHMKLVGAVILALALAMALNIPERVQRAIPDWTAGVQKQISENDTVRGALSSGGGSL
AACRDADPSMLHDCGEAPEFEGLTGWFNTDKPVSTHSGQVTLVDFWAYACINCQRAGEHITKLYDAYRDAGLQVVGVHAP
EYGFEHELANVKDAAKREGINYPVAQDNDFVTWKKYNNRYWPARYLIDAQGNVRHIHEGEGAYKETEQLVRELLREANPQ
VSLPEPVEKGVEKHDAQLTQRRNPETYLGYERARYFTNSNYGPGERTLEFNAPKVGQYTLSGTWEIASDHINPVKDAALS
VNIHAATVQTVVSGTGTLEVTYPDGHTKEFKVADGTVNVVEQDEPLDGIVTVKPSQGVSFYSLTFG

Specific function: Required To Facilitate The Formation Of Correct Disulfide Bonds In Some Periplasmic Proteins And For The Assembly Of The Periplasmic C-Type Cytochromes. Acts By Transferring Electrons From Cytoplasmic Thioredoxin To The Periplasm, Thereby Maintaining The

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42476013, Length=129, Percent_Identity=34.8837209302326, Blast_Score=83, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007528, Length=129, Percent_Identity=32.5581395348837, Blast_Score=83, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR003834
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA; PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 58834; Mature: 58834

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELATIGLIGGIVTGISPCILPVLPVVLAVSVGRRPTHVVAGLALSFATITLLGTVILS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLGLPKDVLRWTGIGLLVIVGLSMMIPKLGELVEEPFSRIPRPTFLQQKARDKGGFMIGL
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
ALGAVYVPCAGPILAAITVAGATGDIGWPTVVLTVAFAVGASLPLLVFALAGNKMGEKID
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
AIRKHMKLVGAVILALALAMALNIPERVQRAIPDWTAGVQKQISENDTVRGALSSGGGSL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCCE
AACRDADPSMLHDCGEAPEFEGLTGWFNTDKPVSTHSGQVTLVDFWAYACINCQRAGEHI
EEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
TKLYDAYRDAGLQVVGVHAPEYGFEHELANVKDAAKREGINYPVAQDNDFVTWKKYNNRY
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
WPARYLIDAQGNVRHIHEGEGAYKETEQLVRELLREANPQVSLPEPVEKGVEKHDAQLTQ
CCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
RRNPETYLGYERARYFTNSNYGPGERTLEFNAPKVGQYTLSGTWEIASDHINPVKDAALS
CCCCCHHHCHHHHHHCCCCCCCCCCCEEEECCCCCCCEEECCEEEECCCCCCCHHHCEEE
VNIHAATVQTVVSGTGTLEVTYPDGHTKEFKVADGTVNVVEQDEPLDGIVTVKPSQGVSF
EEEEHHHHHHHHCCCCEEEEECCCCCCCEEEEECCEEEEEECCCCCCCEEEECCCCCCEE
YSLTFG
EEEECC
>Mature Secondary Structure
MFELATIGLIGGIVTGISPCILPVLPVVLAVSVGRRPTHVVAGLALSFATITLLGTVILS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SLGLPKDVLRWTGIGLLVIVGLSMMIPKLGELVEEPFSRIPRPTFLQQKARDKGGFMIGL
HCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEE
ALGAVYVPCAGPILAAITVAGATGDIGWPTVVLTVAFAVGASLPLLVFALAGNKMGEKID
HHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
AIRKHMKLVGAVILALALAMALNIPERVQRAIPDWTAGVQKQISENDTVRGALSSGGGSL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCCCCE
AACRDADPSMLHDCGEAPEFEGLTGWFNTDKPVSTHSGQVTLVDFWAYACINCQRAGEHI
EEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH
TKLYDAYRDAGLQVVGVHAPEYGFEHELANVKDAAKREGINYPVAQDNDFVTWKKYNNRY
HHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
WPARYLIDAQGNVRHIHEGEGAYKETEQLVRELLREANPQVSLPEPVEKGVEKHDAQLTQ
CCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
RRNPETYLGYERARYFTNSNYGPGERTLEFNAPKVGQYTLSGTWEIASDHINPVKDAALS
CCCCCHHHCHHHHHHCCCCCCCCCCCEEEECCCCCCCEEECCEEEECCCCCCCHHHCEEE
VNIHAATVQTVVSGTGTLEVTYPDGHTKEFKVADGTVNVVEQDEPLDGIVTVKPSQGVSF
EEEEHHHHHHHHCCCCEEEEECCCCCCCEEEEECCEEEEEECCCCCCCEEEECCCCCCEE
YSLTFG
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]