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The map label for this gene is gluP [H]

Identifier: 38232669

GI number: 38232669

Start: 25877

End: 26494

Strand: Direct

Name: gluP [H]

Synonym: DIP0027

Alternate gene names: 38232669

Gene position: 25877-26494 (Clockwise)

Preceding gene: 38232667

Following gene: 38232671

Centisome position: 1.04

GC content: 52.1

Gene sequence:

>618_bases
GTGGTGCATACTGAAGTGATGAACGCACTCAAACGCGCATATGGTCAAGCGCCTGCGACCGCGGTTCTTTGCGCGCTGAC
GATACTTATCTATCTGCTTACTGTTGTGGAGTCCCGCTCGATTGAACACAACCTTAGTGATTCGTGGATTGCAGATCACT
GGACTCTTTATGGTCCGTATTCTCATGGCCTAGGGTGGCTGCGCATGGTGGGGACGGTATTTCTCCACAGCGGGCCCACA
CATCTGGCGTTGAACATGTTTATGCTGTTCTTCTTTGGTCGCGAGATTGAGCATTATTTAGGCAGTGGTCGTTTTACTTT
GGCTTATATCGTGAGCGGGATTGGGGCCTCGGCAACTGTTCTGCTGATGGATCCGCTTGCGCCTACGGTGGGTGCTTCTG
GTGCTGTGTATGGGCTTATGGCGATTTTTGTGGCGATGTCGTACCGGTTGCGTAGGGATCTCACAGCACCGTTGATTCTT
ATCGCAGTGAATGTGGGCTATTCCTTGCTTATGGATGGTGTTTCCCTGTGGGGACATTTGGGTGGCTTGCTGACGGGTTG
TGTGCTGGGGATTGTTTTGGTGATTGCGCAGACTACTCGAGGTAATAAGCGGGGGTGA

Upstream 100 bases:

>100_bases
ACACCAACTGGAGTGCTGGTACTAGATCCCTTGGTCAGTGTGCACCATCAACCCTTCACCATGTTTATGCCATGTGATCG
CATTCTTTAACGAAGTGGGG

Downstream 100 bases:

>100_bases
GATAAGGGGTTTATCTAGGGGCGTCTCGTGTTTGCATGAGGCGCCTATTTTTTGAGAAAATCCTTATCACACAAACCACA
TAAATAACATGAGACCCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPT
HLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLIL
IAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGNKRG

Sequences:

>Translated_205_residues
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPT
HLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLIL
IAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGNKRG
>Mature_205_residues
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPT
HLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLIL
IAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGNKRG

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 22169; Mature: 22169

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPY
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEECCH
SHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEE
LLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GGLLTGCVLGIVLVIAQTTRGNKRG
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPY
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEECCH
SHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEE
LLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHL
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
GGLLTGCVLGIVLVIAQTTRGNKRG
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]