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The map label for this gene is pheA [H]

Identifier: 161598672

GI number: 161598672

Start: 2335434

End: 2336336

Strand: Reverse

Name: pheA [H]

Synonym: DIP2246

Alternate gene names: 161598672

Gene position: 2336336-2335434 (Counterclockwise)

Preceding gene: 38234785

Following gene: 38234781

Centisome position: 93.88

GC content: 63.9

Gene sequence:

>903_bases
ATGAGGATTGCCTATCTCGGGCCAGAAGGAACATTCACCGAAGCCGCATTGTGGAAATTCGCCACCCGCCTCGGACTAGA
ATCCGTCGACACCATTGCGGCCACCAACCCCCGCGAAGCGATCGCCGCCGTCGCCGCAGGACAAGCCGACTACGCCTGCG
TTGCCATCGAAAACTCCGTCGACGGCCCCGTCACCCCTACCTTCGACGCACTCGCCACCATCGACGGCGTGCGCATCTTC
CACGAACTCGACCTCCCCATCGCCTTCGCCATCATGCAGCGCACCGGCGCACCCCTACGCCGCTTTGCCACCCACCCCGT
GGCCTACCAACAGGTAAAAACCTGGCTTGCCGCCAACGCACCCGCAGCCGAATTCGTCCCCGCATCCTCCAACGCCGAGG
CCGCCCGCATGGCCAAAGAAAACATTGTGGACTTTGCCGCAGCCCCCGCCCGCGCCGCAGAAGTGTACGGGCTCGACATC
ATTGCCGACGGCGTTGCCGACGTCACCGGCGCTCGCACCCGATTCGTCCTCGTCGGACACGCCGACACCCCCACCGCACG
CACCGGCCACGACCGCACCTCCGTGGTATTCACACTCAAAAACGAACCCGGCAGCCTCGTCGGTGCACTCTCCGAATTCG
CCATGCGCGGCGTAGACCTCACCCGAATCGAATCCCGCCCCATCGAAGAAGGCCTAGGAACCTACCGATTCCACGTGGAC
ATCAATGGGCATATCGACGACCTCAACGTCGCCGAAGCACTCCGAGCACTCTACCCACGGTGCAACGCGCTAAAATTTAT
CGGTTCGTGGCCAGCCATCTCCGGCCAGCCCGTCACAGCAGTCGACCCCACCGTCGCCCAGGCCGCATCCGCATGGGTAG
AAGCAGCCCGCAACGGTGCCTAA

Upstream 100 bases:

>100_bases
TGATCTGAAGCAGACATCTGAGCCACCTGTGCTGCAAGGAGATCAATCTGCTCATGGATAGGCATGACGAATACCTTACC
GGCCAGATAGAGTAAGACGC

Downstream 100 bases:

>100_bases
TCAGAAAGAGAAATAAGGAAACAACCTTGGGACGTCTCATCCTCATGCGCCACGGGCGCACCTTTGCCAACGCCGCAAAA
GTCCTCGACACTAGGCCCCC

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MRIAYLGPEGTFTEAALWKFATRLGLESVDTIAATNPREAIAAVAAGQADYACVAIENSVDGPVTPTFDALATIDGVRIF
HELDLPIAFAIMQRTGAPLRRFATHPVAYQQVKTWLAANAPAAEFVPASSNAEAARMAKENIVDFAAAPARAAEVYGLDI
IADGVADVTGARTRFVLVGHADTPTARTGHDRTSVVFTLKNEPGSLVGALSEFAMRGVDLTRIESRPIEEGLGTYRFHVD
INGHIDDLNVAEALRALYPRCNALKFIGSWPAISGQPVTAVDPTVAQAASAWVEAARNGA

Sequences:

>Translated_300_residues
MRIAYLGPEGTFTEAALWKFATRLGLESVDTIAATNPREAIAAVAAGQADYACVAIENSVDGPVTPTFDALATIDGVRIF
HELDLPIAFAIMQRTGAPLRRFATHPVAYQQVKTWLAANAPAAEFVPASSNAEAARMAKENIVDFAAAPARAAEVYGLDI
IADGVADVTGARTRFVLVGHADTPTARTGHDRTSVVFTLKNEPGSLVGALSEFAMRGVDLTRIESRPIEEGLGTYRFHVD
INGHIDDLNVAEALRALYPRCNALKFIGSWPAISGQPVTAVDPTVAQAASAWVEAARNGA
>Mature_300_residues
MRIAYLGPEGTFTEAALWKFATRLGLESVDTIAATNPREAIAAVAAGQADYACVAIENSVDGPVTPTFDALATIDGVRIF
HELDLPIAFAIMQRTGAPLRRFATHPVAYQQVKTWLAANAPAAEFVPASSNAEAARMAKENIVDFAAAPARAAEVYGLDI
IADGVADVTGARTRFVLVGHADTPTARTGHDRTSVVFTLKNEPGSLVGALSEFAMRGVDLTRIESRPIEEGLGTYRFHVD
INGHIDDLNVAEALRALYPRCNALKFIGSWPAISGQPVTAVDPTVAQAASAWVEAARNGA

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=287, Percent_Identity=26.8292682926829, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31783; Mature: 31783

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAYLGPEGTFTEAALWKFATRLGLESVDTIAATNPREAIAAVAAGQADYACVAIENSV
CEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCC
DGPVTPTFDALATIDGVRIFHELDLPIAFAIMQRTGAPLRRFATHPVAYQQVKTWLAANA
CCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCC
PAAEFVPASSNAEAARMAKENIVDFAAAPARAAEVYGLDIIADGVADVTGARTRFVLVGH
CHHHEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHEEECCHHHCCCCCEEEEEEEC
ADTPTARTGHDRTSVVFTLKNEPGSLVGALSEFAMRGVDLTRIESRPIEEGLGTYRFHVD
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCHHHCCCEEEEEEE
INGHIDDLNVAEALRALYPRCNALKFIGSWPAISGQPVTAVDPTVAQAASAWVEAARNGA
ECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIAYLGPEGTFTEAALWKFATRLGLESVDTIAATNPREAIAAVAAGQADYACVAIENSV
CEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCC
DGPVTPTFDALATIDGVRIFHELDLPIAFAIMQRTGAPLRRFATHPVAYQQVKTWLAANA
CCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHCCC
PAAEFVPASSNAEAARMAKENIVDFAAAPARAAEVYGLDIIADGVADVTGARTRFVLVGH
CHHHEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHEEECCHHHCCCCCEEEEEEEC
ADTPTARTGHDRTSVVFTLKNEPGSLVGALSEFAMRGVDLTRIESRPIEEGLGTYRFHVD
CCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCHHHCCCEEEEEEE
INGHIDDLNVAEALRALYPRCNALKFIGSWPAISGQPVTAVDPTVAQAASAWVEAARNGA
ECCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3525519; 12948626 [H]