| Definition | Chlorobium tepidum TLS, complete genome. |
|---|---|
| Accession | NC_002932 |
| Length | 2,154,946 |
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The map label for this gene is pol [H]
Identifier: 21675090
GI number: 21675090
Start: 2148442
End: 2150862
Strand: Direct
Name: pol [H]
Synonym: CT2284
Alternate gene names: 21675090
Gene position: 2148442-2150862 (Clockwise)
Preceding gene: 21675089
Following gene: 21675091
Centisome position: 99.7
GC content: 48.66
Gene sequence:
>2421_bases ATGTATTCAATCTTGCTCTCTGGTACCATGAACAACATTGTCAATTTTTCTTTCGAGAATGAACTGCTTTTCGGTAAAGA CCCCGAAGAGAACATTGTTGGAGCGTACCAGCTTAATGATTCGCAAATACGGCTGTTTTTCAGAAAAACGGATGTTGTCA CCCATCGAGATGAGCCATTCTATCCATTCTTTTTTCTCTCAGACAATGAACTGCTTGAAGGTTTTATCCCCTTTAACAAA GAAAAATTCTGGCTGATCCCGCTTGACGGCACAAACTACTACCGGTATCTCGCCATCTTTAGAAGCTGGAAAAATTATCG CGCGGCGCTCGACTTTGTGAACTCCAGTTCTCAGGATTCTTCTTCAAGGAGTGATTCCCAGAACAGCTCAAGCTTTCACA GCCATTTGACCTACAGCCCGGGCGATGCCATCAGCCAGTACCTGATGCAGACCGGTAAAACCCTTTTCAAGGGAATGCTG TTTGACGACCTTCATCGCCTACAGCTCGATATCGAGACCTACTATCAGCCCGACAAGAAGCGAAAAGGAAAAGGTATCGG CGAAGACCCGATCATCATCGTCTCGCTCAGCGACAACCGTTCCTGGGAGCATGTCATTCACTCTAAAGGCAGATCTGAAA AGGATCTACTCGAAGAGCTCGTACACATCATCCGTCAGAAAGATCCGGATGTGATCGAAGGGCACAACATCTTCGGTTTC GATCTTCCCTACCTTCAGCGCCGATGTGAACTGAACGGTGTACGATTCGCTATCGGCCGCAACGGCTTGGTGCCACGTTC TTATCCTGCGACGATCCGCTTTGCCGAGCGATCGGCCGATTTCCAGTTCTGCGACATTCCCGGAAGGCATGTAATCGACA CCTACTTCCTTGTCCAGAATTACGATATCTCGAAACACACGCTTCCGAGCTACGGTTTGAAAGCGGTCGCCAAATTCTTC GGTTTCGCCTCGCCCAACCGTACCTATGTCGACTACAAAAACATCGCCAGCACCTGGGACGACAATCCCGAAACCCTTCT GGCCTACGCGCTCGACGATGTGCGAGAAACCCGTGAACTGGCGGCGCTGCTTTCCGGTAGTAACTTTAGCATGACCAGTA TGGTACCATACAGCTACGCCAATACCGCGAGGCTCGGGCCAGCAGCAAAGATCGAGGCCCTCATAATCCGGGAGTATCTG AAGCGCAAAGTTTCCATCCCTCGTCCATCGATTGGGCAGCAACAGACTGGCGGCTTTACCGAAGTGTTTATCAAAGGCAT TCTCGGGCCAATCGTTTATGCAGACGTCGAATCGCTCTATCCCTCGATCATGCTCACCTTCGATGTTTGCCCAAAATCCG ATTCGCTCAAAGTGTTTCCAACTATCCTGAAGGATCTGAAAGAGTTGCGTTTTGCAGCAAAAAAGCGCGCTGAAGAGGAG AAGGAACGCGGCAACGCCTCGCTGTCGTACAATTTCGATGCCATGCAATCCTCCTTCAAGATCATCATCAATGCCATGTA CGGTTATCTCGGCTTCGGCAACGGCATGTTCAACGATTTTGAGGAAGCTGACCGCGTCACAACCAAAGGACAGGAGATCG CTAAAAAAATGATCCGCGAGTTCGAATCACGTGGCGCCAAAGTAATCGAAGTCGATACCGATGGCATCTTTCTCGTTCCC CCACCCTACGTGGTTACCGAAGAGGAGGAACGGCAGCTGGTCTGTGAAGTTTCATCCACCATGCCGCAGGGAATAAGAAT CGGTTTTGACGGCCGCTTCAAGAAAATGATTTCCTACATGAAGAAAAACTATGCCCTTCTCGATTACAACGAAAAACTGA AGCTGAAAGGATCTGCATTCGTGAGCAGAAGCGGTGAAAAATTCGGCCGGGACTTCGTAAGAGAGGGATTTATCCTGCTC CTCAATGATGACATCCAGGGACTTCATGACCTCTACGTCAAGTATCGCAACGATCTGATAAATCATCGACTCCATATCAG CGATTTTTCCCGAACAGAATCGATGAAAACCACCCTCGATCAGTATGTCTCCGATGTACGGGCCGGTAAGCGCTCCAAAT CGATCACCTACGAAATTGCACTTCGACAGGGGTTGGAAATTGCGAAGGGCGATCGAATCACCTATTATGTTGCCGGCACC GGCAATCCGGCATCGTTCGTTGAGAACGGGCGACTCGCCGAAGAGTGGAACAAGGAACAACCTGATGAAAACACTGGTTT CTATCTGAAACGGCTCGATGAATACGCTCAGAAATTTCTCCCATTCTTCAAGCCTCAGGATTTCAGCTCAATCTTTTCAG CAGATACACTTTTTGCGTTTTCTCCTGAAGGAATCAAAGTGATAAAAGAGATTAGACATCATGAAACCGGTGATCTGTAT CGTGAGAATTCACCCTTTTAA
Upstream 100 bases:
>100_bases TGCGACCATCGGTCAAGCCTCTAGAATTCTCGGGGTCTCTCCGTCCGACGTCTCCATACTCATGATTCGGCTTGGCCGGT AACGCTGTTTCACGTGAAAC
Downstream 100 bases:
>100_bases AAAATTATTGTTTAAACTTTTTATCATCATAAATCATTAAAGTTCAGATTTTTCACAACAAAAACAAATATAAATTATGA CCGATAATAAAATTCTTCCA
Product: DNA polymerase family B protein
Products: NA
Alternate protein names: Pfu polymerase [H]
Number of amino acids: Translated: 806; Mature: 806
Protein sequence:
>806_residues MYSILLSGTMNNIVNFSFENELLFGKDPEENIVGAYQLNDSQIRLFFRKTDVVTHRDEPFYPFFFLSDNELLEGFIPFNK EKFWLIPLDGTNYYRYLAIFRSWKNYRAALDFVNSSSQDSSSRSDSQNSSSFHSHLTYSPGDAISQYLMQTGKTLFKGML FDDLHRLQLDIETYYQPDKKRKGKGIGEDPIIIVSLSDNRSWEHVIHSKGRSEKDLLEELVHIIRQKDPDVIEGHNIFGF DLPYLQRRCELNGVRFAIGRNGLVPRSYPATIRFAERSADFQFCDIPGRHVIDTYFLVQNYDISKHTLPSYGLKAVAKFF GFASPNRTYVDYKNIASTWDDNPETLLAYALDDVRETRELAALLSGSNFSMTSMVPYSYANTARLGPAAKIEALIIREYL KRKVSIPRPSIGQQQTGGFTEVFIKGILGPIVYADVESLYPSIMLTFDVCPKSDSLKVFPTILKDLKELRFAAKKRAEEE KERGNASLSYNFDAMQSSFKIIINAMYGYLGFGNGMFNDFEEADRVTTKGQEIAKKMIREFESRGAKVIEVDTDGIFLVP PPYVVTEEEERQLVCEVSSTMPQGIRIGFDGRFKKMISYMKKNYALLDYNEKLKLKGSAFVSRSGEKFGRDFVREGFILL LNDDIQGLHDLYVKYRNDLINHRLHISDFSRTESMKTTLDQYVSDVRAGKRSKSITYEIALRQGLEIAKGDRITYYVAGT GNPASFVENGRLAEEWNKEQPDENTGFYLKRLDEYAQKFLPFFKPQDFSSIFSADTLFAFSPEGIKVIKEIRHHETGDLY RENSPF
Sequences:
>Translated_806_residues MYSILLSGTMNNIVNFSFENELLFGKDPEENIVGAYQLNDSQIRLFFRKTDVVTHRDEPFYPFFFLSDNELLEGFIPFNK EKFWLIPLDGTNYYRYLAIFRSWKNYRAALDFVNSSSQDSSSRSDSQNSSSFHSHLTYSPGDAISQYLMQTGKTLFKGML FDDLHRLQLDIETYYQPDKKRKGKGIGEDPIIIVSLSDNRSWEHVIHSKGRSEKDLLEELVHIIRQKDPDVIEGHNIFGF DLPYLQRRCELNGVRFAIGRNGLVPRSYPATIRFAERSADFQFCDIPGRHVIDTYFLVQNYDISKHTLPSYGLKAVAKFF GFASPNRTYVDYKNIASTWDDNPETLLAYALDDVRETRELAALLSGSNFSMTSMVPYSYANTARLGPAAKIEALIIREYL KRKVSIPRPSIGQQQTGGFTEVFIKGILGPIVYADVESLYPSIMLTFDVCPKSDSLKVFPTILKDLKELRFAAKKRAEEE KERGNASLSYNFDAMQSSFKIIINAMYGYLGFGNGMFNDFEEADRVTTKGQEIAKKMIREFESRGAKVIEVDTDGIFLVP PPYVVTEEEERQLVCEVSSTMPQGIRIGFDGRFKKMISYMKKNYALLDYNEKLKLKGSAFVSRSGEKFGRDFVREGFILL LNDDIQGLHDLYVKYRNDLINHRLHISDFSRTESMKTTLDQYVSDVRAGKRSKSITYEIALRQGLEIAKGDRITYYVAGT GNPASFVENGRLAEEWNKEQPDENTGFYLKRLDEYAQKFLPFFKPQDFSSIFSADTLFAFSPEGIKVIKEIRHHETGDLY RENSPF >Mature_806_residues MYSILLSGTMNNIVNFSFENELLFGKDPEENIVGAYQLNDSQIRLFFRKTDVVTHRDEPFYPFFFLSDNELLEGFIPFNK EKFWLIPLDGTNYYRYLAIFRSWKNYRAALDFVNSSSQDSSSRSDSQNSSSFHSHLTYSPGDAISQYLMQTGKTLFKGML FDDLHRLQLDIETYYQPDKKRKGKGIGEDPIIIVSLSDNRSWEHVIHSKGRSEKDLLEELVHIIRQKDPDVIEGHNIFGF DLPYLQRRCELNGVRFAIGRNGLVPRSYPATIRFAERSADFQFCDIPGRHVIDTYFLVQNYDISKHTLPSYGLKAVAKFF GFASPNRTYVDYKNIASTWDDNPETLLAYALDDVRETRELAALLSGSNFSMTSMVPYSYANTARLGPAAKIEALIIREYL KRKVSIPRPSIGQQQTGGFTEVFIKGILGPIVYADVESLYPSIMLTFDVCPKSDSLKVFPTILKDLKELRFAAKKRAEEE KERGNASLSYNFDAMQSSFKIIINAMYGYLGFGNGMFNDFEEADRVTTKGQEIAKKMIREFESRGAKVIEVDTDGIFLVP PPYVVTEEEERQLVCEVSSTMPQGIRIGFDGRFKKMISYMKKNYALLDYNEKLKLKGSAFVSRSGEKFGRDFVREGFILL LNDDIQGLHDLYVKYRNDLINHRLHISDFSRTESMKTTLDQYVSDVRAGKRSKSITYEIALRQGLEIAKGDRITYYVAGT GNPASFVENGRLAEEWNKEQPDENTGFYLKRLDEYAQKFLPFFKPQDFSSIFSADTLFAFSPEGIKVIKEIRHHETGDLY RENSPF
Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity [H]
COG id: COG0417
COG function: function code L; DNA polymerase elongation subunit (family B)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DNA polymerase type-B family [H]
Homologues:
Organism=Homo sapiens, GI106507301, Length=609, Percent_Identity=22.1674876847291, Blast_Score=75, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6320101, Length=581, Percent_Identity=25.3012048192771, Blast_Score=89, Evalue=4e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006172 - InterPro: IPR017964 - InterPro: IPR006133 - InterPro: IPR006134 - InterPro: IPR004578 - InterPro: IPR023211 - InterPro: IPR012337 [H]
Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 92538; Mature: 92538
Theoretical pI: Translated: 6.58; Mature: 6.58
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MYSILLSGTMNNIVNFSFENELLFGKDPEENIVGAYQLNDSQIRLFFRKTDVVTHRDEPF CCEEEEECCHHHHEEECCCCCEEECCCCCCCCEEEEEECCCEEEEEEEECCEEEECCCCC YPFFFLSDNELLEGFIPFNKEKFWLIPLDGTNYYRYLAIFRSWKNYRAALDFVNSSSQDS CEEEEECCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC SSRSDSQNSSSFHSHLTYSPGDAISQYLMQTGKTLFKGMLFDDLHRLQLDIETYYQPDKK CCCCCCCCCCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCHH RKGKGIGEDPIIIVSLSDNRSWEHVIHSKGRSEKDLLEELVHIIRQKDPDVIEGHNIFGF HCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECCCCEEEC DLPYLQRRCELNGVRFAIGRNGLVPRSYPATIRFAERSADFQFCDIPGRHVIDTYFLVQN CCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCCHHHEEEEEEEC YDISKHTLPSYGLKAVAKFFGFASPNRTYVDYKNIASTWDDNPETLLAYALDDVRETREL CCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHH AALLSGSNFSMTSMVPYSYANTARLGPAAKIEALIIREYLKRKVSIPRPSIGQQQTGGFT HHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH EVFIKGILGPIVYADVESLYPSIMLTFDVCPKSDSLKVFPTILKDLKELRFAAKKRAEEE HHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH KERGNASLSYNFDAMQSSFKIIINAMYGYLGFGNGMFNDFEEADRVTTKGQEIAKKMIRE HHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH FESRGAKVIEVDTDGIFLVPPPYVVTEEEERQLVCEVSSTMPQGIRIGFDGRFKKMISYM HHHCCCEEEEEECCCEEEECCCEEECCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHH KKNYALLDYNEKLKLKGSAFVSRSGEKFGRDFVREGFILLLNDDIQGLHDLYVKYRNDLI HHCCEEEECCCCEEECCCHHHHCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH NHRLHISDFSRTESMKTTLDQYVSDVRAGKRSKSITYEIALRQGLEIAKGDRITYYVAGT HCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEC GNPASFVENGRLAEEWNKEQPDENTGFYLKRLDEYAQKFLPFFKPQDFSSIFSADTLFAF CCHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEE SPEGIKVIKEIRHHETGDLYRENSPF CCCHHHHHHHHHCCCCCCCCCCCCCC >Mature Secondary Structure MYSILLSGTMNNIVNFSFENELLFGKDPEENIVGAYQLNDSQIRLFFRKTDVVTHRDEPF CCEEEEECCHHHHEEECCCCCEEECCCCCCCCEEEEEECCCEEEEEEEECCEEEECCCCC YPFFFLSDNELLEGFIPFNKEKFWLIPLDGTNYYRYLAIFRSWKNYRAALDFVNSSSQDS CEEEEECCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC SSRSDSQNSSSFHSHLTYSPGDAISQYLMQTGKTLFKGMLFDDLHRLQLDIETYYQPDKK CCCCCCCCCCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCCHH RKGKGIGEDPIIIVSLSDNRSWEHVIHSKGRSEKDLLEELVHIIRQKDPDVIEGHNIFGF HCCCCCCCCCEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECCCCEEEC DLPYLQRRCELNGVRFAIGRNGLVPRSYPATIRFAERSADFQFCDIPGRHVIDTYFLVQN CCHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEECCCCCHHHEEEEEEEC YDISKHTLPSYGLKAVAKFFGFASPNRTYVDYKNIASTWDDNPETLLAYALDDVRETREL CCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEHHHHHHCCCCCHHHHHHHHHHHHHHHHHH AALLSGSNFSMTSMVPYSYANTARLGPAAKIEALIIREYLKRKVSIPRPSIGQQQTGGFT HHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH EVFIKGILGPIVYADVESLYPSIMLTFDVCPKSDSLKVFPTILKDLKELRFAAKKRAEEE HHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH KERGNASLSYNFDAMQSSFKIIINAMYGYLGFGNGMFNDFEEADRVTTKGQEIAKKMIRE HHHCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH FESRGAKVIEVDTDGIFLVPPPYVVTEEEERQLVCEVSSTMPQGIRIGFDGRFKKMISYM HHHCCCEEEEEECCCEEEECCCEEECCCHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHH KKNYALLDYNEKLKLKGSAFVSRSGEKFGRDFVREGFILLLNDDIQGLHDLYVKYRNDLI HHCCEEEECCCCEEECCCHHHHCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHH NHRLHISDFSRTESMKTTLDQYVSDVRAGKRSKSITYEIALRQGLEIAKGDRITYYVAGT HCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEEC GNPASFVENGRLAEEWNKEQPDENTGFYLKRLDEYAQKFLPFFKPQDFSSIFSADTLFAF CCHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEE SPEGIKVIKEIRHHETGDLYRENSPF CCCHHHHHHHHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8441634; 1762925; 1579479 [H]