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The map label for this gene is surA [H]

Identifier: 21675072

GI number: 21675072

Start: 2128988

End: 2130304

Strand: Reverse

Name: surA [H]

Synonym: CT2264

Alternate gene names: 21675072

Gene position: 2130304-2128988 (Counterclockwise)

Preceding gene: 21675073

Following gene: 21675068

Centisome position: 98.86

GC content: 53.0

Gene sequence:

>1317_bases
ATGAAAAAAGTATTGTTTGCTGTGCTTGCCGCCTTGATGATCGCCATGAACGGTTTTGCCGATGCCGCCGCTTCGACTGG
CCTTGACCGAATCGTGGCTATTGTGGGTAACGAAATCATTCTCGCTTCCGATGTCAACGAGCAGGAGTTGATGTTGCACC
TTCAGTATCCTGAAACCAGAAAGGATCCCCAGCTCCGGAAGCGGATTCTGGAGAATATGATTAATCAGAAAATCATTTTG
ACCAAGGCGAAGATCGATACGGTCAAGGTCGATGAGAAGAGCGTCGATGACCAGGCAGCCGCGCGATACAGCTCCCTTCG
CGCTGGTTTTCCGTCGGTAAGCGCCATGGAGTCGAGATTCGGTATGCCGGTCAATCGCCTGAAGCAGCATATCCGCGAAG
ACATCCGCGATCAGCAGATGATCGAGGCTTTCCGGCGGAAGAATTTCCACGAAGTGACAGTGTCGTACGACGAGACGATG
GCCTTCTACAATCAGGAAAAGGGGGCGTTGCCCGAGGCGCCTGAGACGGTTTCGGTTTCACAAATCATCAAAATGCCACT
AGTCTCTGAAGCCGCAAGGCAGGCCGCGCTCGATAAAATCAAGGCGGTTCAGCAGCAGCTTGAAGCGGGGGGTAGCTTTG
CTACCCTTGCCCGTGAATATTCCGATGATCCAGGCTCAAGGGAAAAAGGGGGTGACCTGGGCTTCACCCGGAAAGGCGAG
CTGGTCCCAAGTTTCGAAGAGGCGGCATCTGTGCTCAAACCGGGGCAGATTTCCGGCATTGTCGAGACCCGTTTCGGCTA
CCACATCATCCAGCTCATCGATAAGGAAGGCGACCGCATCCACACCCGGCACATTCTCGCCCTGTTCGACCGGAGCAAAA
CTGATATTCCTGCAACCATTGCGCTCCTGAAATCCATCAGGAAGGATGTTCTTTCCGGGAAGGCAACATTCGCCGAAATG
GCTAAAAAGTATTCTGACGATCCGGCCTCTGCCACGAATGGCGGACTGATCACATCCGGTTCAGGGAATCCCGATCTTGA
GGTCGCCACACTCAGGCCCGATCTTCGGAAAATCATCGATGGGTTGAAAAGCAAAGGAGATATCAGTCAACCGGAGAAGA
TTGAGTCGGATAAGAGCGCTCCGTTTTATGCGCTTTTCATGCTCAACTCAAGAACGCCTGCGCACGTTCTGACGCCGGAG
CATGACTTCGCTCAAATCCAGGAGCTGGCCCTGAACCACAAGAGCCAGGAGCTGTTCAACGCCTGGATTGAAAAGCTGAA
AAAAGAGGTGGTGGTGAAGGTTATGTCAGACATCTAA

Upstream 100 bases:

>100_bases
CCGGAGAACGGATTGCGTCGTTGTGCCGGATCATCACGATGGACAAGTGTTTCCCGGTTACGTCCCGGAACCTGTCCCCA
CCAGAAAACTCCTGATCTTT

Downstream 100 bases:

>100_bases
ACGTCTGACATAACGGGCATTCTTCTCGATAAAGTCTCGGCGGGGTTCGACCTTGTCGCCCATCAGGGTTGAAAAGACCT
GGTCGGCCTCCATGGCGTTT

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKKVLFAVLAALMIAMNGFADAAASTGLDRIVAIVGNEIILASDVNEQELMLHLQYPETRKDPQLRKRILENMINQKIIL
TKAKIDTVKVDEKSVDDQAAARYSSLRAGFPSVSAMESRFGMPVNRLKQHIREDIRDQQMIEAFRRKNFHEVTVSYDETM
AFYNQEKGALPEAPETVSVSQIIKMPLVSEAARQAALDKIKAVQQQLEAGGSFATLAREYSDDPGSREKGGDLGFTRKGE
LVPSFEEAASVLKPGQISGIVETRFGYHIIQLIDKEGDRIHTRHILALFDRSKTDIPATIALLKSIRKDVLSGKATFAEM
AKKYSDDPASATNGGLITSGSGNPDLEVATLRPDLRKIIDGLKSKGDISQPEKIESDKSAPFYALFMLNSRTPAHVLTPE
HDFAQIQELALNHKSQELFNAWIEKLKKEVVVKVMSDI

Sequences:

>Translated_438_residues
MKKVLFAVLAALMIAMNGFADAAASTGLDRIVAIVGNEIILASDVNEQELMLHLQYPETRKDPQLRKRILENMINQKIIL
TKAKIDTVKVDEKSVDDQAAARYSSLRAGFPSVSAMESRFGMPVNRLKQHIREDIRDQQMIEAFRRKNFHEVTVSYDETM
AFYNQEKGALPEAPETVSVSQIIKMPLVSEAARQAALDKIKAVQQQLEAGGSFATLAREYSDDPGSREKGGDLGFTRKGE
LVPSFEEAASVLKPGQISGIVETRFGYHIIQLIDKEGDRIHTRHILALFDRSKTDIPATIALLKSIRKDVLSGKATFAEM
AKKYSDDPASATNGGLITSGSGNPDLEVATLRPDLRKIIDGLKSKGDISQPEKIESDKSAPFYALFMLNSRTPAHVLTPE
HDFAQIQELALNHKSQELFNAWIEKLKKEVVVKVMSDI
>Mature_438_residues
MKKVLFAVLAALMIAMNGFADAAASTGLDRIVAIVGNEIILASDVNEQELMLHLQYPETRKDPQLRKRILENMINQKIIL
TKAKIDTVKVDEKSVDDQAAARYSSLRAGFPSVSAMESRFGMPVNRLKQHIREDIRDQQMIEAFRRKNFHEVTVSYDETM
AFYNQEKGALPEAPETVSVSQIIKMPLVSEAARQAALDKIKAVQQQLEAGGSFATLAREYSDDPGSREKGGDLGFTRKGE
LVPSFEEAASVLKPGQISGIVETRFGYHIIQLIDKEGDRIHTRHILALFDRSKTDIPATIALLKSIRKDVLSGKATFAEM
AKKYSDDPASATNGGLITSGSGNPDLEVATLRPDLRKIIDGLKSKGDISQPEKIESDKSAPFYALFMLNSRTPAHVLTPE
HDFAQIQELALNHKSQELFNAWIEKLKKEVVVKVMSDI

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=459, Percent_Identity=27.8867102396514, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48563; Mature: 48563

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLFAVLAALMIAMNGFADAAASTGLDRIVAIVGNEIILASDVNEQELMLHLQYPETR
CHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCC
KDPQLRKRILENMINQKIILTKAKIDTVKVDEKSVDDQAAARYSSLRAGFPSVSAMESRF
CCHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHC
GMPVNRLKQHIREDIRDQQMIEAFRRKNFHEVTVSYDETMAFYNQEKGALPEAPETVSVS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCHH
QIIKMPLVSEAARQAALDKIKAVQQQLEAGGSFATLAREYSDDPGSREKGGDLGFTRKGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LVPSFEEAASVLKPGQISGIVETRFGYHIIQLIDKEGDRIHTRHILALFDRSKTDIPATI
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHH
ALLKSIRKDVLSGKATFAEMAKKYSDDPASATNGGLITSGSGNPDLEVATLRPDLRKIID
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCHHHHHHHH
GLKSKGDISQPEKIESDKSAPFYALFMLNSRTPAHVLTPEHDFAQIQELALNHKSQELFN
HHCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHCCHHHHHHH
AWIEKLKKEVVVKVMSDI
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVLFAVLAALMIAMNGFADAAASTGLDRIVAIVGNEIILASDVNEQELMLHLQYPETR
CHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCEEEEEECCCCC
KDPQLRKRILENMINQKIILTKAKIDTVKVDEKSVDDQAAARYSSLRAGFPSVSAMESRF
CCHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHC
GMPVNRLKQHIREDIRDQQMIEAFRRKNFHEVTVSYDETMAFYNQEKGALPEAPETVSVS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCHH
QIIKMPLVSEAARQAALDKIKAVQQQLEAGGSFATLAREYSDDPGSREKGGDLGFTRKGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LVPSFEEAASVLKPGQISGIVETRFGYHIIQLIDKEGDRIHTRHILALFDRSKTDIPATI
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHH
ALLKSIRKDVLSGKATFAEMAKKYSDDPASATNGGLITSGSGNPDLEVATLRPDLRKIID
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEECCHHHHHHHH
GLKSKGDISQPEKIESDKSAPFYALFMLNSRTPAHVLTPEHDFAQIQELALNHKSQELFN
HHCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCEEECCCHHHHHHHHHHHCCHHHHHHH
AWIEKLKKEVVVKVMSDI
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA