Click here to switch to the map view.

The map label for this gene is dapD [H]

Identifier: 21675067

GI number: 21675067

Start: 2123131

End: 2123991

Strand: Reverse

Name: dapD [H]

Synonym: CT2259

Alternate gene names: 21675067

Gene position: 2123991-2123131 (Counterclockwise)

Preceding gene: 21675068

Following gene: 21675066

Centisome position: 98.56

GC content: 60.28

Gene sequence:

>861_bases
ATGGAACAGTATCATCAGATCAAGGAACAGATTATTGCATTTTCTTTACTGAGCGCCGACCAGCTCAAGGCCGATGCCCA
GGTCAAGTCGGTGTTTGCCGAATTCAAGACCCTGCTCAATGAGGGCAAAATTCGTGCAGCCGAACCTTCGGGCGACGGCT
GGACGGTTAACCAGTGGGTCAAACAGGGGATTCTCGTTGGCATGAAGCTCGGCGTGCTGATCGAAAGCCACGTTGATCTC
GCTGGTCTTGGCAGTGCCTCGTTCATCGATAAAGACACCTACCCGCTTCGTGAGTTTACCGCGGCAGATGGCGTCCGGAT
TGTGCCTGGCGGCTCGTCGGTGCGCGACGGCGCGTACCTCGCTCCATCGGTGGTGATGATGCCGCCGGCCTACGTTAACG
TCGGTGGTTACGTCGATGAAGGCTCGATGATCGACTCGCACGCGCTGGTGGGCAGTTGCGCCCAGATCGGCAAGAAGGTT
CACCTCTCTGCTGCTGTGCAGATCGGCGGAGTGCTCGAACCGGTTGGCGCGATGCCAGTCATTATCGAGGACGAGGTGAT
GGTCGGCGGTAACTGCGGCATCTACGAAGGCACCATTGTCAAAAAGCGCGCCGTCATCGGCACCGGCGTTATCCTTAACG
GCTCCACGCCGGTCTACGATCTGGTCAACGGAACGGTGCTGCGCAAGAGCGCCGCCGGCCCGCTCGTCATTCCCGAAGGT
GCGGTGGTGGTGGCCGGTTCCCGCCAGGTCAAGGGCGAGTTCGCCGCCGAACACGGCCTGTCGATCTACACGCCGCTGAT
CGTCAAGTACCGCGACGAGCGCACCGACAGCGCCACGGCTCTCGAAAGCGCGCTCAGATGA

Upstream 100 bases:

>100_bases
TCCGATGAAAGCCTGCGCAGCGACGATTTCCGCTTCTACAACCGGAAGACGGGTGCTGACATCACCGCCGAGTTTAACTG
AAAAAGAGAACCACAGCCTA

Downstream 100 bases:

>100_bases
GCTGGTTCACAACTCAGCGGCACTCTGGTCTTTGCCGTGATTTTGGCCGCAGGTGGCGGCGCGTTGCGACGATCTCATCC
GCCATTGCGCTGATCTGCGC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MEQYHQIKEQIIAFSLLSADQLKADAQVKSVFAEFKTLLNEGKIRAAEPSGDGWTVNQWVKQGILVGMKLGVLIESHVDL
AGLGSASFIDKDTYPLREFTAADGVRIVPGGSSVRDGAYLAPSVVMMPPAYVNVGGYVDEGSMIDSHALVGSCAQIGKKV
HLSAAVQIGGVLEPVGAMPVIIEDEVMVGGNCGIYEGTIVKKRAVIGTGVILNGSTPVYDLVNGTVLRKSAAGPLVIPEG
AVVVAGSRQVKGEFAAEHGLSIYTPLIVKYRDERTDSATALESALR

Sequences:

>Translated_286_residues
MEQYHQIKEQIIAFSLLSADQLKADAQVKSVFAEFKTLLNEGKIRAAEPSGDGWTVNQWVKQGILVGMKLGVLIESHVDL
AGLGSASFIDKDTYPLREFTAADGVRIVPGGSSVRDGAYLAPSVVMMPPAYVNVGGYVDEGSMIDSHALVGSCAQIGKKV
HLSAAVQIGGVLEPVGAMPVIIEDEVMVGGNCGIYEGTIVKKRAVIGTGVILNGSTPVYDLVNGTVLRKSAAGPLVIPEG
AVVVAGSRQVKGEFAAEHGLSIYTPLIVKYRDERTDSATALESALR
>Mature_286_residues
MEQYHQIKEQIIAFSLLSADQLKADAQVKSVFAEFKTLLNEGKIRAAEPSGDGWTVNQWVKQGILVGMKLGVLIESHVDL
AGLGSASFIDKDTYPLREFTAADGVRIVPGGSSVRDGAYLAPSVVMMPPAYVNVGGYVDEGSMIDSHALVGSCAQIGKKV
HLSAAVQIGGVLEPVGAMPVIIEDEVMVGGNCGIYEGTIVKKRAVIGTGVILNGSTPVYDLVNGTVLRKSAAGPLVIPEG
AVVVAGSRQVKGEFAAEHGLSIYTPLIVKYRDERTDSATALESALR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=268, Percent_Identity=37.6865671641791, Blast_Score=148, Evalue=3e-37,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 30108; Mature: 30108

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQYHQIKEQIIAFSLLSADQLKADAQVKSVFAEFKTLLNEGKIRAAEPSGDGWTVNQWV
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
KQGILVGMKLGVLIESHVDLAGLGSASFIDKDTYPLREFTAADGVRIVPGGSSVRDGAYL
HHHHHHHHHHHEEEECCCCEECCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEE
APSVVMMPPAYVNVGGYVDEGSMIDSHALVGSCAQIGKKVHLSAAVQIGGVLEPVGAMPV
CCEEEECCCCEEECCCEECCCCEECHHHHHHHHHHHCCEEEEEEHEEECCEECCCCCCCE
IIEDEVMVGGNCGIYEGTIVKKRAVIGTGVILNGSTPVYDLVNGTVLRKSAAGPLVIPEG
EEECCEEECCCCCEECCCEEEEEEEEEEEEEECCCCCHHHHHCCEEEEECCCCCEEECCC
AVVVAGSRQVKGEFAAEHGLSIYTPLIVKYRDERTDSATALESALR
CEEEECCCCCCCHHHHHCCCEEECEEEEEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MEQYHQIKEQIIAFSLLSADQLKADAQVKSVFAEFKTLLNEGKIRAAEPSGDGWTVNQWV
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
KQGILVGMKLGVLIESHVDLAGLGSASFIDKDTYPLREFTAADGVRIVPGGSSVRDGAYL
HHHHHHHHHHHEEEECCCCEECCCCCCCCCCCCCCHHHHHCCCCEEEECCCCCCCCCCEE
APSVVMMPPAYVNVGGYVDEGSMIDSHALVGSCAQIGKKVHLSAAVQIGGVLEPVGAMPV
CCEEEECCCCEEECCCEECCCCEECHHHHHHHHHHHCCEEEEEEHEEECCEECCCCCCCE
IIEDEVMVGGNCGIYEGTIVKKRAVIGTGVILNGSTPVYDLVNGTVLRKSAAGPLVIPEG
EEECCEEECCCCCEECCCEEEEEEEEEEEEEECCCCCHHHHHCCEEEEECCCCCEEECCC
AVVVAGSRQVKGEFAAEHGLSIYTPLIVKYRDERTDSATALESALR
CEEEECCCCCCCHHHHHCCCEEECEEEEEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA