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The map label for this gene is mpg1 [H]

Identifier: 21674866

GI number: 21674866

Start: 1951796

End: 1952725

Strand: Direct

Name: mpg1 [H]

Synonym: CT2056

Alternate gene names: 21674866

Gene position: 1951796-1952725 (Clockwise)

Preceding gene: 21674865

Following gene: 21674867

Centisome position: 90.57

GC content: 58.28

Gene sequence:

>930_bases
ATGAACGCTTTCGTCCTGGCTGCGGGTTTCGGCACCCGCCTGCAGCCGCTGACCGACACGATGCCCAAACCGCTCGTTCC
GGTGCTGAACGTGCCGAGCCTCTGCTACTCGCTGTTCCTGCTCAAGGAGGCGGGCATCCGCAAAGCGATCATCAATATCC
ACCACCACACGGAGAGCCTTCGACAATTTTTTGACCGCCACGATTTCGGCAGCCTCGAAATCGTACTCTCGGAGGAGCGT
GAAATTCTCGGCACCGGCGGCGGACTGAAAAAATGCGAGCACTTGCTCGATGGAGAAGAGTTCGTGCTCATCAACAGCGA
CATCATCAGCGACATCAACCTGCGCTCGCTCATCGACGCGCACCAGCGCTCTGGCTGCGGCGGCACGCTCGCGCTCTATG
AAACTCCGCTGGCGGCGCAGATAGGGTATATCGGTGTGCGCGACGGACTGGTGCTTGATTTCAGGAACCAGCGCGGCACC
GGCCTCTCGTCATCGTTTATCTACACCGGAACGGCGGTGTTCAACCCCGAGATTTTCCGCCACCTGAAAACCGAGTTTTC
CGGCATTGTCGAAACTGGCTTTTATGGGTTGGCAGACAACGGGAGGCTGGCATTGTTCGAGCATCGCGGATTGTGGCAGG
ATATTGGCACCCTGCCGAATTTTTACCGCGCAAACCTCGACGATAATTTGCGTATTCTTCAGCTTGCGGGGCGCATACAA
CGGGAGATCGGCTTTTTTCCGCACATGATTTCAGATGATGCGTCGATCAACCCCGAGGCCCACGTCGAAAATTCGGTGCT
CGGCGCGAACTGCGCGATAGCCGCCGAAGCCATCGTGGAGCACTCGGTGCTCCTGCCCGGCACCATCATCGAACGCGGCG
AGACGCTTCGTAACGCAATCGCCGCACCAGGCATCCGCATTCCACTGTAA

Upstream 100 bases:

>100_bases
TCGCGGCAACCCTCAGCTACCTGAGAGAGTACATCGAAGCCAGGCCTGAACTTGCCATGGCTGGCCGCCTGCTCAAACCG
ATCATTCCCGAAATTTCGCG

Downstream 100 bases:

>100_bases
ACTCCCGACAGCGCAAACGGCAACGGCATGGTCATCAACGGTCTCGACATACTCCTCCAGAATCCCGAAGTCCTGCGCCA
CCGGCGCGTCGGCCTGATCG

Product: mannose-1-phosphate guanylyltransferase, putative

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MNAFVLAAGFGTRLQPLTDTMPKPLVPVLNVPSLCYSLFLLKEAGIRKAIINIHHHTESLRQFFDRHDFGSLEIVLSEER
EILGTGGGLKKCEHLLDGEEFVLINSDIISDINLRSLIDAHQRSGCGGTLALYETPLAAQIGYIGVRDGLVLDFRNQRGT
GLSSSFIYTGTAVFNPEIFRHLKTEFSGIVETGFYGLADNGRLALFEHRGLWQDIGTLPNFYRANLDDNLRILQLAGRIQ
REIGFFPHMISDDASINPEAHVENSVLGANCAIAAEAIVEHSVLLPGTIIERGETLRNAIAAPGIRIPL

Sequences:

>Translated_309_residues
MNAFVLAAGFGTRLQPLTDTMPKPLVPVLNVPSLCYSLFLLKEAGIRKAIINIHHHTESLRQFFDRHDFGSLEIVLSEER
EILGTGGGLKKCEHLLDGEEFVLINSDIISDINLRSLIDAHQRSGCGGTLALYETPLAAQIGYIGVRDGLVLDFRNQRGT
GLSSSFIYTGTAVFNPEIFRHLKTEFSGIVETGFYGLADNGRLALFEHRGLWQDIGTLPNFYRANLDDNLRILQLAGRIQ
REIGFFPHMISDDASINPEAHVENSVLGANCAIAAEAIVEHSVLLPGTIIERGETLRNAIAAPGIRIPL
>Mature_309_residues
MNAFVLAAGFGTRLQPLTDTMPKPLVPVLNVPSLCYSLFLLKEAGIRKAIINIHHHTESLRQFFDRHDFGSLEIVLSEER
EILGTGGGLKKCEHLLDGEEFVLINSDIISDINLRSLIDAHQRSGCGGTLALYETPLAAQIGYIGVRDGLVLDFRNQRGT
GLSSSFIYTGTAVFNPEIFRHLKTEFSGIVETGFYGLADNGRLALFEHRGLWQDIGTLPNFYRANLDDNLRILQLAGRIQ
REIGFFPHMISDDASINPEAHVENSVLGANCAIAAEAIVEHSVLLPGTIIERGETLRNAIAAPGIRIPL

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761619, Length=305, Percent_Identity=27.2131147540984, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI11761621, Length=305, Percent_Identity=27.2131147540984, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI133931050, Length=299, Percent_Identity=28.4280936454849, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320148, Length=314, Percent_Identity=26.1146496815287, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21355443, Length=302, Percent_Identity=26.4900662251656, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24644084, Length=302, Percent_Identity=26.4900662251656, Blast_Score=110, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 33940; Mature: 33940

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFVLAAGFGTRLQPLTDTMPKPLVPVLNVPSLCYSLFLLKEAGIRKAIINIHHHTESL
CCEEEEEECCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RQFFDRHDFGSLEIVLSEEREILGTGGGLKKCEHLLDGEEFVLINSDIISDINLRSLIDA
HHHHHHCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCEEEEEECHHHCCCHHHHHHHH
HQRSGCGGTLALYETPLAAQIGYIGVRDGLVLDFRNQRGTGLSSSFIYTGTAVFNPEIFR
HHCCCCCCEEEEECCCHHHHCCEEEECCCEEEEECCCCCCCCCCCEEEECEEEECHHHHH
HLKTEFSGIVETGFYGLADNGRLALFEHRGLWQDIGTLPNFYRANLDDNLRILQLAGRIQ
HHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHCCCCCEECCCCCCHHHHHHHHHHH
REIGFFPHMISDDASINPEAHVENSVLGANCAIAAEAIVEHSVLLPGTIIERGETLRNAI
HHHCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHHHHHH
AAPGIRIPL
HCCCCCCCC
>Mature Secondary Structure
MNAFVLAAGFGTRLQPLTDTMPKPLVPVLNVPSLCYSLFLLKEAGIRKAIINIHHHTESL
CCEEEEEECCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RQFFDRHDFGSLEIVLSEEREILGTGGGLKKCEHLLDGEEFVLINSDIISDINLRSLIDA
HHHHHHCCCCCEEEEEECCCCEEECCCCHHHHHHHHCCCEEEEEECHHHCCCHHHHHHHH
HQRSGCGGTLALYETPLAAQIGYIGVRDGLVLDFRNQRGTGLSSSFIYTGTAVFNPEIFR
HHCCCCCCEEEEECCCHHHHCCEEEECCCEEEEECCCCCCCCCCCEEEECEEEECHHHHH
HLKTEFSGIVETGFYGLADNGRLALFEHRGLWQDIGTLPNFYRANLDDNLRILQLAGRIQ
HHHHHHHHHHHHCCEEECCCCCEEEEECCCCHHHHHCCCCCEECCCCCCHHHHHHHHHHH
REIGFFPHMISDDASINPEAHVENSVLGANCAIAAEAIVEHSVLLPGTIIERGETLRNAI
HHHCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCHHHHHHH
AAPGIRIPL
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]