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The map label for this gene is cfa [H]

Identifier: 21674780

GI number: 21674780

Start: 1866939

End: 1868081

Strand: Direct

Name: cfa [H]

Synonym: CT1969

Alternate gene names: 21674780

Gene position: 1866939-1868081 (Clockwise)

Preceding gene: 21674779

Following gene: 21674782

Centisome position: 86.64

GC content: 60.19

Gene sequence:

>1143_bases
ATGAGCGGCATTTACGAAAGCAAATTGCGAGCGCTGCTCGAATCGGCGGGCATCGCCATCGGAGGCAGCAATCCGTGGGA
CATCACCGTCCACAATCCGCATTTCTACAAGCGCGTCGTCACTGAGTCGCACCTCGGCATCGGCGAATCGTACATGGACG
GCTGGTGGGACTGCGAGGCGCTCGACCAGTTCTTTTACCGTGTGCTTCGCGCACGGCTCGACGCGAAAGTTTCGCAAGCG
AGCCGCGCCCTCGGCAACATCCTCGGCGTGCTCGTCAACCTGCAAAAACCCTCGCGGGCATTCACGGTCGGCGAAGTCCA
CTACAACGTGGGCAACGACCTGTACGAGGCAATGCTCGACAAGCGGATGCTCTACAGTTGCGGCTACTGGAAAGACGCCC
GCAACCTCAACGAAGCGCAGGAGAACAAACTGCGCCTCATCTTCAACAAGCTTGAACTCCAGCCCGGAATGCGGGTGCTC
GACATCGGCTGCGGCTGGGGCGGCGCGGCACGCTTCGCAGCGGAGCACTACGGCGTGAGCGTCACCGGCGTCACGGTATC
GAGCGAGCAGAAGAAGATGGCCGACAAGCTGCGAAACAACCTCCCGGTCGAGGTGCGGCTCGTCGATTACCGCCAGCTCG
ACGGCAGCTTTGACCGCATCTACTCCATCGGCATGTTCGAGCACGTGGGCGTAAAAAACTACCGGCGCTTTTTCGAGATC
GCACGCAACTGCCTCAAAAGCGACGGCCTGTTCCTGCTGCATACCATCGGCAGCAAACGCTCCTCGACCCACACCGACAA
ATGGACGCACAAGTACATCTTTCCCAACTCTATGCTCCCGTCGGCCCGGCAGATCACCACAGCCGCCGAGGGCCAGCAGC
TCATCGAGGACTGGCACGCCTTCGGCAACGACTACGACCGCACCCTCATGGCCTGGCACCGGAACTTCGAAGAGCACTGG
CCGCAACTTCGCCACGCCTACGACGAGCGCTTCTACCGTATGTGGCGCTACTACCTGCTCAGCGCCGCCGGATCGTTCCG
AGCCCGAAACGTCCAGCTCTGGCAGATACTCTTTTCAAACAACGGAATTACCGGGGATTATTACGTGCCGCGGGAACACA
AAGCCGTCCTGTTGAAAAACTGA

Upstream 100 bases:

>100_bases
GCGCTTTCGGAGCAGAAGATCAGTGAGATCGAAGCCTTTCTCGCCTCCATGCCTGCATAAACGCGCAAAAAACAGCTACG
CCAACCTCACCGGAGAAGCT

Downstream 100 bases:

>100_bases
CGGACACAATCGCCTTCCCCGCACCACGAAACCATAAAAAAAGCCCCATGTCTGAAACATGAGGCTGGGGAAGTCCTGTG
TTCTGAAGAAAAATCAGCTG

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSGIYESKLRALLESAGIAIGGSNPWDITVHNPHFYKRVVTESHLGIGESYMDGWWDCEALDQFFYRVLRARLDAKVSQA
SRALGNILGVLVNLQKPSRAFTVGEVHYNVGNDLYEAMLDKRMLYSCGYWKDARNLNEAQENKLRLIFNKLELQPGMRVL
DIGCGWGGAARFAAEHYGVSVTGVTVSSEQKKMADKLRNNLPVEVRLVDYRQLDGSFDRIYSIGMFEHVGVKNYRRFFEI
ARNCLKSDGLFLLHTIGSKRSSTHTDKWTHKYIFPNSMLPSARQITTAAEGQQLIEDWHAFGNDYDRTLMAWHRNFEEHW
PQLRHAYDERFYRMWRYYLLSAAGSFRARNVQLWQILFSNNGITGDYYVPREHKAVLLKN

Sequences:

>Translated_380_residues
MSGIYESKLRALLESAGIAIGGSNPWDITVHNPHFYKRVVTESHLGIGESYMDGWWDCEALDQFFYRVLRARLDAKVSQA
SRALGNILGVLVNLQKPSRAFTVGEVHYNVGNDLYEAMLDKRMLYSCGYWKDARNLNEAQENKLRLIFNKLELQPGMRVL
DIGCGWGGAARFAAEHYGVSVTGVTVSSEQKKMADKLRNNLPVEVRLVDYRQLDGSFDRIYSIGMFEHVGVKNYRRFFEI
ARNCLKSDGLFLLHTIGSKRSSTHTDKWTHKYIFPNSMLPSARQITTAAEGQQLIEDWHAFGNDYDRTLMAWHRNFEEHW
PQLRHAYDERFYRMWRYYLLSAAGSFRARNVQLWQILFSNNGITGDYYVPREHKAVLLKN
>Mature_379_residues
SGIYESKLRALLESAGIAIGGSNPWDITVHNPHFYKRVVTESHLGIGESYMDGWWDCEALDQFFYRVLRARLDAKVSQAS
RALGNILGVLVNLQKPSRAFTVGEVHYNVGNDLYEAMLDKRMLYSCGYWKDARNLNEAQENKLRLIFNKLELQPGMRVLD
IGCGWGGAARFAAEHYGVSVTGVTVSSEQKKMADKLRNNLPVEVRLVDYRQLDGSFDRIYSIGMFEHVGVKNYRRFFEIA
RNCLKSDGLFLLHTIGSKRSSTHTDKWTHKYIFPNSMLPSARQITTAAEGQQLIEDWHAFGNDYDRTLMAWHRNFEEHWP
QLRHAYDERFYRMWRYYLLSAAGSFRARNVQLWQILFSNNGITGDYYVPREHKAVLLKN

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=349, Percent_Identity=56.1604584527221, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI133904226, Length=391, Percent_Identity=28.3887468030691, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 43972; Mature: 43840

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIYESKLRALLESAGIAIGGSNPWDITVHNPHFYKRVVTESHLGIGESYMDGWWDCEA
CCCHHHHHHHHHHHHCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCHHH
LDQFFYRVLRARLDAKVSQASRALGNILGVLVNLQKPSRAFTVGEVHYNVGNDLYEAMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH
KRMLYSCGYWKDARNLNEAQENKLRLIFNKLELQPGMRVLDIGCGWGGAARFAAEHYGVS
HHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEE
VTGVTVSSEQKKMADKLRNNLPVEVRLVDYRQLDGSFDRIYSIGMFEHVGVKNYRRFFEI
EEEEEECHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHCCHHHHCCHHHHHHHHHH
ARNCLKSDGLFLLHTIGSKRSSTHTDKWTHKYIFPNSMLPSARQITTAAEGQQLIEDWHA
HHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FGNDYDRTLMAWHRNFEEHWPQLRHAYDERFYRMWRYYLLSAAGSFRARNVQLWQILFSN
HCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEC
NGITGDYYVPREHKAVLLKN
CCCCCCEECCCCCCEEEECC
>Mature Secondary Structure 
SGIYESKLRALLESAGIAIGGSNPWDITVHNPHFYKRVVTESHLGIGESYMDGWWDCEA
CCHHHHHHHHHHHHCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCHHH
LDQFFYRVLRARLDAKVSQASRALGNILGVLVNLQKPSRAFTVGEVHYNVGNDLYEAMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHH
KRMLYSCGYWKDARNLNEAQENKLRLIFNKLELQPGMRVLDIGCGWGGAARFAAEHYGVS
HHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCEE
VTGVTVSSEQKKMADKLRNNLPVEVRLVDYRQLDGSFDRIYSIGMFEHVGVKNYRRFFEI
EEEEEECHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHCCHHHHCCHHHHHHHHHH
ARNCLKSDGLFLLHTIGSKRSSTHTDKWTHKYIFPNSMLPSARQITTAAEGQQLIEDWHA
HHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
FGNDYDRTLMAWHRNFEEHWPQLRHAYDERFYRMWRYYLLSAAGSFRARNVQLWQILFSN
HCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEC
NGITGDYYVPREHKAVLLKN
CCCCCCEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]