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The map label for this gene is fkpB [C]

Identifier: 21674708

GI number: 21674708

Start: 1795048

End: 1795476

Strand: Reverse

Name: fkpB [C]

Synonym: CT1896

Alternate gene names: 21674708

Gene position: 1795476-1795048 (Counterclockwise)

Preceding gene: 21674709

Following gene: 21674707

Centisome position: 83.32

GC content: 59.91

Gene sequence:

>429_bases
ATGGCACAGGCCAAAAAAGGCGACAAGGTTCTGGTTCACTACACCGGCACCTATGATGACGGCACGGTTTTCGACAGCTC
CGTGGAGCGCGGGCCGCTGGAGGTTACCATCGGCACCGGCATGGTGATTCCCGGCTTCGACCGCGCGCTGCTCGACATGG
AGCCGGGCCAGAAGAAGACGGTCAACATTCCCGTTGACGACGCGTATGGCCCGAGAGCCGAAGAGCTTATCGCCGAAGTT
CCGCGTGAGCGGATTCCTGCCGAAATTCCGCTTGAAATCGGCCAGCAGTTGCAACTCAGCCTCGCCGACGGCGGCGAAGT
GATCGTGATGATCGTCGATCTGACCGACACCACCGTCACGCTCGACGCCAACCACCCGATGGCTGGTCTCGACCTGAACT
TCGAACTTGAACTGGTCGAAATCCTCTGA

Upstream 100 bases:

>100_bases
AATTTTTTTGTGTGGGCAGTCGTTGGCTTTCGGTTCTTTGGAGAGTTGATGGTCTTTCTGGCGGATGTCCCGATTTTAAA
TGATAGAAGGAGAACGAGTT

Downstream 100 bases:

>100_bases
TTTCATCCCGGGCGCCGTTCCGTTCCGCAAATTCCCCGGGCGGAACGGCGTTTTTGATGCCTTCGCTCCTGTGCTGCTGA
CGAGCGTCGTCAAACCGGCA

Product: peptidyl-prolyl cis-trans isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MAQAKKGDKVLVHYTGTYDDGTVFDSSVERGPLEVTIGTGMVIPGFDRALLDMEPGQKKTVNIPVDDAYGPRAEELIAEV
PRERIPAEIPLEIGQQLQLSLADGGEVIVMIVDLTDTTVTLDANHPMAGLDLNFELELVEIL

Sequences:

>Translated_142_residues
MAQAKKGDKVLVHYTGTYDDGTVFDSSVERGPLEVTIGTGMVIPGFDRALLDMEPGQKKTVNIPVDDAYGPRAEELIAEV
PRERIPAEIPLEIGQQLQLSLADGGEVIVMIVDLTDTTVTLDANHPMAGLDLNFELELVEIL
>Mature_141_residues
AQAKKGDKVLVHYTGTYDDGTVFDSSVERGPLEVTIGTGMVIPGFDRALLDMEPGQKKTVNIPVDDAYGPRAEELIAEVP
RERIPAEIPLEIGQQLQLSLADGGEVIVMIVDLTDTTVTLDANHPMAGLDLNFELELVEIL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=72, Percent_Identity=44.4444444444444, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI17149844, Length=72, Percent_Identity=44.4444444444444, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI17149842, Length=72, Percent_Identity=44.4444444444444, Blast_Score=67, Evalue=5e-12,
Organism=Homo sapiens, GI7706131, Length=66, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI219842220, Length=69, Percent_Identity=44.9275362318841, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI4503727, Length=99, Percent_Identity=38.3838383838384, Blast_Score=63, Evalue=8e-11,
Organism=Escherichia coli, GI1786211, Length=138, Percent_Identity=31.1594202898551, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1789748, Length=128, Percent_Identity=35.15625, Blast_Score=68, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540882, Length=72, Percent_Identity=44.4444444444444, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=70, Percent_Identity=48.5714285714286, Blast_Score=67, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=75, Percent_Identity=46.6666666666667, Blast_Score=66, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655568, Length=71, Percent_Identity=49.2957746478873, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15388; Mature: 15257

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAKKGDKVLVHYTGTYDDGTVFDSSVERGPLEVTIGTGMVIPGFDRALLDMEPGQKKT
CCCCCCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCEEECCCCCEEEECCCCCCEE
VNIPVDDAYGPRAEELIAEVPRERIPAEIPLEIGQQLQLSLADGGEVIVMIVDLTDTTVT
EEECCCCCCCCCHHHHHHHCCHHHCCEECCCCCCCEEEEEECCCCEEEEEEEECCCCEEE
LDANHPMAGLDLNFELELVEIL
EECCCCEECCCCCEEEEEEEEC
>Mature Secondary Structure 
AQAKKGDKVLVHYTGTYDDGTVFDSSVERGPLEVTIGTGMVIPGFDRALLDMEPGQKKT
CCCCCCCEEEEEEECCCCCCEEECCCCCCCCEEEEECCCEEECCCCCEEEECCCCCCEE
VNIPVDDAYGPRAEELIAEVPRERIPAEIPLEIGQQLQLSLADGGEVIVMIVDLTDTTVT
EEECCCCCCCCCHHHHHHHCCHHHCCEECCCCCCCEEEEEECCCCEEEEEEEECCCCEEE
LDANHPMAGLDLNFELELVEIL
EECCCCEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]