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The map label for this gene is estA [H]

Identifier: 21674669

GI number: 21674669

Start: 1756139

End: 1756843

Strand: Direct

Name: estA [H]

Synonym: CT1856

Alternate gene names: 21674669

Gene position: 1756139-1756843 (Clockwise)

Preceding gene: 21674668

Following gene: 21674670

Centisome position: 81.49

GC content: 61.28

Gene sequence:

>705_bases
ATGTACCGGATTCACAACACCAACCCATTCCCTATGTTCACACGCAATAACGACGCTTTTACCTGGCTCGATTACAACCG
CAATCCCGATAAAAAGAGTCCGCTGCTCGTGATGCTTCACGGCTACGGGAGCAATGAACGGGACCTCATCATGCTGGCCC
CCACGCTCGACCCCCGGCTTCGCGTCGTGAGCGTGCGCGCGCCGCTCGTGCTCGCTCCGGAGATGTACGGCTGGTTCCCG
ATCGAGTTCACGCCGGGCGGCATTACAGTGGATCGCGAGGCGGCGCGGCAGGTGGCCGAAAAACTGGTGACGTTTCTCGA
ACATCTCATCGAAAAGCTCCAGCCAACCGGCGAAAAAACCTTCCTCATGGGCTTCAGCCAGGGGTCGGTGATGAGCTACC
TGACTGCGTTCCGAAATCCGGAGTTGCTGCATGGCGTGGTCGCCCTCAGCGGGCAGCTTCCCGATGCGCGTCCCGAGGCT
GGGGCCTTACCCGAAGCTCTCGGTGATGTGCCGTTCCTCGTGCAGCACGGGCTGTTCGACGACGTGCTGCCCATCGACCG
GGGCCGTCAGGCCAATGCGTGGCTCCGCGACAGAATCGCCGACCTCACCTACCGCGAATATCCGATGGCGCACCAGATCA
ACCAGGCGTCGCTCGATTTCCTTGCTTCGTGGCTTTCGGAGCGCATCGACCGGGTCGTTTCGTGA

Upstream 100 bases:

>100_bases
CTTCAGCCCAATTTCTTTTTCCAGAGACCTTTTCGACAGGTTATCAACAAACCACTACTATATCAGGGCAGAGAAGCAGG
TCTGCCCCTACAGGTTAATC

Downstream 100 bases:

>100_bases
CCCGGTTACCCTTCCGGCGGATGGGGGGATTTGAGCGCTTTTTTGCTTACCTTGTAGATCATTTTTTCCAATTTCCAACC
GCCGCTGCATGAACGACAAT

Product: serine esterase

Products: NA

Alternate protein names: Esterase I [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MYRIHNTNPFPMFTRNNDAFTWLDYNRNPDKKSPLLVMLHGYGSNERDLIMLAPTLDPRLRVVSVRAPLVLAPEMYGWFP
IEFTPGGITVDREAARQVAEKLVTFLEHLIEKLQPTGEKTFLMGFSQGSVMSYLTAFRNPELLHGVVALSGQLPDARPEA
GALPEALGDVPFLVQHGLFDDVLPIDRGRQANAWLRDRIADLTYREYPMAHQINQASLDFLASWLSERIDRVVS

Sequences:

>Translated_234_residues
MYRIHNTNPFPMFTRNNDAFTWLDYNRNPDKKSPLLVMLHGYGSNERDLIMLAPTLDPRLRVVSVRAPLVLAPEMYGWFP
IEFTPGGITVDREAARQVAEKLVTFLEHLIEKLQPTGEKTFLMGFSQGSVMSYLTAFRNPELLHGVVALSGQLPDARPEA
GALPEALGDVPFLVQHGLFDDVLPIDRGRQANAWLRDRIADLTYREYPMAHQINQASLDFLASWLSERIDRVVS
>Mature_234_residues
MYRIHNTNPFPMFTRNNDAFTWLDYNRNPDKKSPLLVMLHGYGSNERDLIMLAPTLDPRLRVVSVRAPLVLAPEMYGWFP
IEFTPGGITVDREAARQVAEKLVTFLEHLIEKLQPTGEKTFLMGFSQGSVMSYLTAFRNPELLHGVVALSGQLPDARPEA
GALPEALGDVPFLVQHGLFDDVLPIDRGRQANAWLRDRIADLTYREYPMAHQINQASLDFLASWLSERIDRVVS

Specific function: Hydrolyzes carboxylic ester bonds with relatively broad substrate specificity [H]

COG id: COG0400

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003140 [H]

Pfam domain/function: PF02230 Abhydrolase_2 [H]

EC number: =3.1.1.1 [H]

Molecular weight: Translated: 26534; Mature: 26534

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIHNTNPFPMFTRNNDAFTWLDYNRNPDKKSPLLVMLHGYGSNERDLIMLAPTLDPRL
CEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCE
RVVSVRAPLVLAPEMYGWFPIEFTPGGITVDREAARQVAEKLVTFLEHLIEKLQPTGEKT
EEEEECCCEEECCCCCCEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FLMGFSQGSVMSYLTAFRNPELLHGVVALSGQLPDARPEAGALPEALGDVPFLVQHGLFD
EEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCC
DVLPIDRGRQANAWLRDRIADLTYREYPMAHQINQASLDFLASWLSERIDRVVS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYRIHNTNPFPMFTRNNDAFTWLDYNRNPDKKSPLLVMLHGYGSNERDLIMLAPTLDPRL
CEEECCCCCCCEEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCE
RVVSVRAPLVLAPEMYGWFPIEFTPGGITVDREAARQVAEKLVTFLEHLIEKLQPTGEKT
EEEEECCCEEECCCCCCEEEEEEECCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FLMGFSQGSVMSYLTAFRNPELLHGVVALSGQLPDARPEAGALPEALGDVPFLVQHGLFD
EEEECCCCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCHHHHHCCCCC
DVLPIDRGRQANAWLRDRIADLTYREYPMAHQINQASLDFLASWLSERIDRVVS
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA