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The map label for this gene is yuxG [H]

Identifier: 21674588

GI number: 21674588

Start: 1680321

End: 1682405

Strand: Reverse

Name: yuxG [H]

Synonym: CT1774

Alternate gene names: 21674588

Gene position: 1682405-1680321 (Counterclockwise)

Preceding gene: 21674589

Following gene: 21674587

Centisome position: 78.07

GC content: 61.82

Gene sequence:

>2085_bases
ATGGAGGCTGGCCGTATCGACGCCGCCGATACTCCCGCGGAACTGGTAGAGCTGGTCTATGCGTCGAGGCTGCTGGGCAA
GGATGACCGGCTGGTCATGCACGGCGGCGGCAATACCTCCGTGAAGTGCGAACTGACCGATTTTATCGGCAACCATGTCA
ACGTCATCTTCATCAAGGCGAGCGGCGTCAATCTGGCGTCGGTCGATGCCGGAGATTTCACGCCGGTGCGCATCGATCCT
CTCCGCAAGCTCCAAAAGATGTACGAGTCCGGGCAGCGGCACAGCGAGGAGGATATCCGCCGTTTCTCGACCAGGGAGTT
CAAGAATTTCCTCTATCTCAACCTCTTTACCCTGACCGATCACATGGTGAGCCGGTCGCTAAGCCCGTCGATCGAGACGC
TGCTCCACGCCTTTCTGCCACACCGCTACATTCTCCATACCCACTCGCTGGCCCTGCTCACGCTGAGCAACCAGACCGAT
GGCGAGCGTCTTTGCCGCGAGGCACTTGGCGATGGCTACGGACAGGTTCCCTACATCCAGCCTGGTCTCGGCCTGGCCAA
TCTCGCCCATGACGCATACGAGAAGAATCCCTCTATCGAGGGGCTCGTGCTGCACAAGCATGGTCTGGTGACCTTCGGTG
ATTCGGCCAAGGAGGCGTATGATCGCATGATCGACGGCGTCAACCGCATCGAGGAGCGCATCGCTTCCGCCGCCCGCAAG
GTGTTCGCTTCGGCTCCGATGCCGACAGCGATCGCCAGCGTCGAAGAGGTTGCCCCCATTGTGCGCGGCGCGTGTTCGTT
TGAGAAAACCCCCGGTGAGAAGGATTACCAGAGCTTCGTGCTTGAATTCAGAACCTCGCCCGCGCTGCTCGATTATCTCA
AGATCGCCGACCTCGAAGCGTTCAGCAAAAAAGGGGCGATGACGCCGGATTTCATCATTCGCACCAAGAATCACCCCCTT
GTGGCTCCGGCACCGGATGCCGCCGATCTTGAAGGGTTCGGCAAGGAACTCAGGGCGCGCGCCAAACGCTTCACGGAGGA
GTATCGCAGCTACTTCGAGCGCCAGCAGCAGGCGACCGGCATGGATGTTTCCATGATCGATCCGATGCCGCGCGTGGTGC
TGGTGCCGGGGCTGGGGCTGTTTGGCCTGGGCCTTTCGGCAGCCGACGCGAAGCTCACGGCGGATATCGCCGAGCACTCG
GCGGTGGCGATGCTCGACGCCGAGTCGATCGGTTGCTTCGAGTCGATCTCCGAGAAGGAGGCTTTTGAGATCGAGTACTG
GGATATGGAGCAGGCCAAGGTGCGCAAGAGCCATAACGGCGGCGAGTTCGCTGGCAAGGTGGCGCTCGTCACCGGCGGCG
CGGGTGCCATCGGCCTTGCCACGGCGAAGGCGTTCAAGGCCAAAGGCGCGGAGATTGTCATCATGGATATCGATCCGGCC
GCGCTCGAAAAGGCTGCGGCTGAACTCGGCTCCGGCACGCTCACGATTCCGTGCGACGTCACGAATGCCGCTGCGGTTCG
CGAGGCGTTCGACACGGTCTGCCGCACCTTCGGCGGCCTCGACATCGTCGTCTCGAACGTCGGCGTCGCATGGCAGGGCA
GAATTGGTGATGTCTCCGACGAGCTGCTCCGCAGGAGCTTTGAATTGAACTTCTTCTCGCACCAGACCGTTTCGCAGAAC
GCTGTCAGGATCATGCGCCGTCAGGGCATCGGTGGTGTGCTGCTTTACAACGTTTCCAAGCAGGCGGTCAATCCCGGTCC
GGATTTTGGCCCGTACGGTCTGCCCAAAGCCGCGACGCTCTTTTTGCTCCGACAGTACGCGCTCGATCACGGGCGCGACG
GTATCCGCGCCAACGGCGTCAACGCCGACCGCATTCGCAGCGGCCTGCTCACGCCGGAGATGATCAAGGCCCGTTCGGCG
GCGCGCGGCCTTTCCGAAAGAGATTATATGGCCGGCAATCTGCTCGGCCTCGAAGTGTCGGCGGAGGATGTGGCGGATGC
GTTCGTCCATCTGGCGCTCGAAACCAAGACGACCGGCTCGATCACCACGGTGGACGGAGGCAACATCGCCGCCGCGCTGC
GGTAA

Upstream 100 bases:

>100_bases
GGGTCAGCATTCCTGAGCAGCGCATCGCAACTTTAACCGTGATTACAGGAATAGTTCAATCCTTATGAAGAATCTCTGGA
ACGAGTCCGATCTGAACATG

Downstream 100 bases:

>100_bases
TCAATAGCGTAGCTTTTCATTTAAAACCATAACCGAACCAGGAGATCACACGATGGCGGAGTACGATAAGGACAAACAGG
CGAAAGAGTATTACACCGAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MEAGRIDAADTPAELVELVYASRLLGKDDRLVMHGGGNTSVKCELTDFIGNHVNVIFIKASGVNLASVDAGDFTPVRIDP
LRKLQKMYESGQRHSEEDIRRFSTREFKNFLYLNLFTLTDHMVSRSLSPSIETLLHAFLPHRYILHTHSLALLTLSNQTD
GERLCREALGDGYGQVPYIQPGLGLANLAHDAYEKNPSIEGLVLHKHGLVTFGDSAKEAYDRMIDGVNRIEERIASAARK
VFASAPMPTAIASVEEVAPIVRGACSFEKTPGEKDYQSFVLEFRTSPALLDYLKIADLEAFSKKGAMTPDFIIRTKNHPL
VAPAPDAADLEGFGKELRARAKRFTEEYRSYFERQQQATGMDVSMIDPMPRVVLVPGLGLFGLGLSAADAKLTADIAEHS
AVAMLDAESIGCFESISEKEAFEIEYWDMEQAKVRKSHNGGEFAGKVALVTGGAGAIGLATAKAFKAKGAEIVIMDIDPA
ALEKAAAELGSGTLTIPCDVTNAAAVREAFDTVCRTFGGLDIVVSNVGVAWQGRIGDVSDELLRRSFELNFFSHQTVSQN
AVRIMRRQGIGGVLLYNVSKQAVNPGPDFGPYGLPKAATLFLLRQYALDHGRDGIRANGVNADRIRSGLLTPEMIKARSA
ARGLSERDYMAGNLLGLEVSAEDVADAFVHLALETKTTGSITTVDGGNIAAALR

Sequences:

>Translated_694_residues
MEAGRIDAADTPAELVELVYASRLLGKDDRLVMHGGGNTSVKCELTDFIGNHVNVIFIKASGVNLASVDAGDFTPVRIDP
LRKLQKMYESGQRHSEEDIRRFSTREFKNFLYLNLFTLTDHMVSRSLSPSIETLLHAFLPHRYILHTHSLALLTLSNQTD
GERLCREALGDGYGQVPYIQPGLGLANLAHDAYEKNPSIEGLVLHKHGLVTFGDSAKEAYDRMIDGVNRIEERIASAARK
VFASAPMPTAIASVEEVAPIVRGACSFEKTPGEKDYQSFVLEFRTSPALLDYLKIADLEAFSKKGAMTPDFIIRTKNHPL
VAPAPDAADLEGFGKELRARAKRFTEEYRSYFERQQQATGMDVSMIDPMPRVVLVPGLGLFGLGLSAADAKLTADIAEHS
AVAMLDAESIGCFESISEKEAFEIEYWDMEQAKVRKSHNGGEFAGKVALVTGGAGAIGLATAKAFKAKGAEIVIMDIDPA
ALEKAAAELGSGTLTIPCDVTNAAAVREAFDTVCRTFGGLDIVVSNVGVAWQGRIGDVSDELLRRSFELNFFSHQTVSQN
AVRIMRRQGIGGVLLYNVSKQAVNPGPDFGPYGLPKAATLFLLRQYALDHGRDGIRANGVNADRIRSGLLTPEMIKARSA
ARGLSERDYMAGNLLGLEVSAEDVADAFVHLALETKTTGSITTVDGGNIAAALR
>Mature_694_residues
MEAGRIDAADTPAELVELVYASRLLGKDDRLVMHGGGNTSVKCELTDFIGNHVNVIFIKASGVNLASVDAGDFTPVRIDP
LRKLQKMYESGQRHSEEDIRRFSTREFKNFLYLNLFTLTDHMVSRSLSPSIETLLHAFLPHRYILHTHSLALLTLSNQTD
GERLCREALGDGYGQVPYIQPGLGLANLAHDAYEKNPSIEGLVLHKHGLVTFGDSAKEAYDRMIDGVNRIEERIASAARK
VFASAPMPTAIASVEEVAPIVRGACSFEKTPGEKDYQSFVLEFRTSPALLDYLKIADLEAFSKKGAMTPDFIIRTKNHPL
VAPAPDAADLEGFGKELRARAKRFTEEYRSYFERQQQATGMDVSMIDPMPRVVLVPGLGLFGLGLSAADAKLTADIAEHS
AVAMLDAESIGCFESISEKEAFEIEYWDMEQAKVRKSHNGGEFAGKVALVTGGAGAIGLATAKAFKAKGAEIVIMDIDPA
ALEKAAAELGSGTLTIPCDVTNAAAVREAFDTVCRTFGGLDIVVSNVGVAWQGRIGDVSDELLRRSFELNFFSHQTVSQN
AVRIMRRQGIGGVLLYNVSKQAVNPGPDFGPYGLPKAATLFLLRQYALDHGRDGIRANGVNADRIRSGLLTPEMIKARSA
ARGLSERDYMAGNLLGLEVSAEDVADAFVHLALETKTTGSITTVDGGNIAAALR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=30.1587301587302, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=29.8039215686275, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=28.9473684210526, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=26.0700389105058, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=26.984126984127, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=33, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=272, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=200, Percent_Identity=33, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=31.5, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=206, Percent_Identity=29.6116504854369, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=203, Percent_Identity=32.512315270936, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=26.9372693726937, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24663911, Length=183, Percent_Identity=31.6939890710383, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665243, Length=189, Percent_Identity=29.6296296296296, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR013454
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short; PF00596 Aldolase_II [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 75165; Mature: 75165

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAGRIDAADTPAELVELVYASRLLGKDDRLVMHGGGNTSVKCELTDFIGNHVNVIFIKA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHHHHCCCEEEEEEEE
SGVNLASVDAGDFTPVRIDPLRKLQKMYESGQRHSEEDIRRFSTREFKNFLYLNLFTLTD
CCCEEEECCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEHHHHHH
HMVSRSLSPSIETLLHAFLPHRYILHTHSLALLTLSNQTDGERLCREALGDGYGQVPYIQ
HHHHCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEC
PGLGLANLAHDAYEKNPSIEGLVLHKHGLVTFGDSAKEAYDRMIDGVNRIEERIASAARK
CCCCHHHHHHHHHHCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFASAPMPTAIASVEEVAPIVRGACSFEKTPGEKDYQSFVLEFRTSPALLDYLKIADLEA
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FSKKGAMTPDFIIRTKNHPLVAPAPDAADLEGFGKELRARAKRFTEEYRSYFERQQQATG
HHHCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MDVSMIDPMPRVVLVPGLGLFGLGLSAADAKLTADIAEHSAVAMLDAESIGCFESISEKE
CCEEECCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHCCCC
AFEIEYWDMEQAKVRKSHNGGEFAGKVALVTGGAGAIGLATAKAFKAKGAEIVIMDIDPA
CEEEEECCCHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHH
ALEKAAAELGSGTLTIPCDVTNAAAVREAFDTVCRTFGGLDIVVSNVGVAWQGRIGDVSD
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCHHH
ELLRRSFELNFFSHQTVSQNAVRIMRRQGIGGVLLYNVSKQAVNPGPDFGPYGLPKAATL
HHHHHHHCCCEECCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCHHHHH
FLLRQYALDHGRDGIRANGVNADRIRSGLLTPEMIKARSAARGLSERDYMAGNLLGLEVS
HHHHHHHHHCCCCCCEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
AEDVADAFVHLALETKTTGSITTVDGGNIAAALR
HHHHHHHHHEEEEEECCCCCEEEECCCCEEEECC
>Mature Secondary Structure
MEAGRIDAADTPAELVELVYASRLLGKDDRLVMHGGGNTSVKCELTDFIGNHVNVIFIKA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEHHHHCCCEEEEEEEE
SGVNLASVDAGDFTPVRIDPLRKLQKMYESGQRHSEEDIRRFSTREFKNFLYLNLFTLTD
CCCEEEECCCCCCCCEEECHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEHHHHHH
HMVSRSLSPSIETLLHAFLPHRYILHTHSLALLTLSNQTDGERLCREALGDGYGQVPYIQ
HHHHCCCCHHHHHHHHHHCCCCEEEEECCEEEEEECCCCCHHHHHHHHHCCCCCCCCEEC
PGLGLANLAHDAYEKNPSIEGLVLHKHGLVTFGDSAKEAYDRMIDGVNRIEERIASAARK
CCCCHHHHHHHHHHCCCCCCEEEEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
VFASAPMPTAIASVEEVAPIVRGACSFEKTPGEKDYQSFVLEFRTSPALLDYLKIADLEA
HHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FSKKGAMTPDFIIRTKNHPLVAPAPDAADLEGFGKELRARAKRFTEEYRSYFERQQQATG
HHHCCCCCCCEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MDVSMIDPMPRVVLVPGLGLFGLGLSAADAKLTADIAEHSAVAMLDAESIGCFESISEKE
CCEEECCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHCCEEEEEECCCCCHHHHHCCCC
AFEIEYWDMEQAKVRKSHNGGEFAGKVALVTGGAGAIGLATAKAFKAKGAEIVIMDIDPA
CEEEEECCCHHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHH
ALEKAAAELGSGTLTIPCDVTNAAAVREAFDTVCRTFGGLDIVVSNVGVAWQGRIGDVSD
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCHHH
ELLRRSFELNFFSHQTVSQNAVRIMRRQGIGGVLLYNVSKQAVNPGPDFGPYGLPKAATL
HHHHHHHCCCEECCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCCCCCCHHHHH
FLLRQYALDHGRDGIRANGVNADRIRSGLLTPEMIKARSAARGLSERDYMAGNLLGLEVS
HHHHHHHHHCCCCCCEECCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
AEDVADAFVHLALETKTTGSITTVDGGNIAAALR
HHHHHHHHHEEEEEECCCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 8188684 [H]