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The map label for this gene is ilvE [H]

Identifier: 21674423

GI number: 21674423

Start: 1512108

End: 1513019

Strand: Direct

Name: ilvE [H]

Synonym: CT1605

Alternate gene names: 21674423

Gene position: 1512108-1513019 (Clockwise)

Preceding gene: 21674422

Following gene: 21674424

Centisome position: 70.17

GC content: 58.22

Gene sequence:

>912_bases
ATGGATAACTCGCTTAAAATATGGATGAACGGCGAACTGGTCGGCTGGAGTGACGCCAAAATCCACGTCATGTCCCACGT
CGTCCACTATGGTTCGTCAACCTTCGAGGGCATCCGCTGTTACGATACCGTCAAAGGCTCGGCGCTGCTCTTCCTCGACG
AACATGTCCGCCGCCTCTGGGAATCTTCGAAAATCTACCGCATAGAGATTCCCTATTCGGAAACCGAGATCAAGGACGCC
ATTATCTCGACCATCAAGGCCAACAACCACAAGGCCTGCTACGTCCGTCCGCTGGTTTTCCGTGGTCAGGGCGCGCTTGG
CGTCAATCCGCACCGCGCCTCCATCGAGGTCGCCATCGCGACCTGGGAGTGGGGCACCTACCTCGGCGAGGATGTGCTTG
AAAATGGCGTGGATGTCAAGGTCTCCTCATGGCACCGCCTCGCCCCGAACACCCTGCCCTCATGGGCCAAAGCAGGCGGC
AACTACATGAACTCGCAGCTCATCAAAATGGAGGCGCTGTCGGACGGTTACGCCGAAGGACTGGCGCTCGACCACAACGG
CTACGTTGCCGAGGGCAGCGGCGAAAACATCTTTGTCGTCAGGAACAACATCATTTACACCCCGCTGGCCGCGCAGTCGA
TCCTGCCGGGCTTTACCCGTCACGCTGTGATGCACATCGCCAGGGAGCTTGGCTACGAGGTTCGCGAAACGCCCATTCCG
CGCGAGGCGCTTTACATCGCCGACGAAATCTTCCTGACCGGCACGGCTGCCGAGATCACCCCAGTCAGAAGCGTTGACAG
AATCCCGATTGGCAACGAACACCGCGGCCCGGTCACCGAAGCCTTGCAGCACGAGTACCTCAAAATCGTCCATTCCGGAG
AAGACCCATACAACTGGCTGACCTTTATTTGA

Upstream 100 bases:

>100_bases
CGCGCTCAAATGAGCTCCTCGCCGCTTTCAAAAAAGCCAAAACAGACTATCTTAGAAGAAAAATTCTTTACCGTTTTTTT
CACTCAATTTCATCAGTTTT

Downstream 100 bases:

>100_bases
GCGGAGGGGCATGAGCTGGAATTCGATTGTCGGTCACGAACCACAACTCCGGGTGCTGAAAACAGCGCTCGGAGCCAACC
GTTTGGCTCATGCCTATCTC

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MDNSLKIWMNGELVGWSDAKIHVMSHVVHYGSSTFEGIRCYDTVKGSALLFLDEHVRRLWESSKIYRIEIPYSETEIKDA
IISTIKANNHKACYVRPLVFRGQGALGVNPHRASIEVAIATWEWGTYLGEDVLENGVDVKVSSWHRLAPNTLPSWAKAGG
NYMNSQLIKMEALSDGYAEGLALDHNGYVAEGSGENIFVVRNNIIYTPLAAQSILPGFTRHAVMHIARELGYEVRETPIP
REALYIADEIFLTGTAAEITPVRSVDRIPIGNEHRGPVTEALQHEYLKIVHSGEDPYNWLTFI

Sequences:

>Translated_303_residues
MDNSLKIWMNGELVGWSDAKIHVMSHVVHYGSSTFEGIRCYDTVKGSALLFLDEHVRRLWESSKIYRIEIPYSETEIKDA
IISTIKANNHKACYVRPLVFRGQGALGVNPHRASIEVAIATWEWGTYLGEDVLENGVDVKVSSWHRLAPNTLPSWAKAGG
NYMNSQLIKMEALSDGYAEGLALDHNGYVAEGSGENIFVVRNNIIYTPLAAQSILPGFTRHAVMHIARELGYEVRETPIP
REALYIADEIFLTGTAAEITPVRSVDRIPIGNEHRGPVTEALQHEYLKIVHSGEDPYNWLTFI
>Mature_303_residues
MDNSLKIWMNGELVGWSDAKIHVMSHVVHYGSSTFEGIRCYDTVKGSALLFLDEHVRRLWESSKIYRIEIPYSETEIKDA
IISTIKANNHKACYVRPLVFRGQGALGVNPHRASIEVAIATWEWGTYLGEDVLENGVDVKVSSWHRLAPNTLPSWAKAGG
NYMNSQLIKMEALSDGYAEGLALDHNGYVAEGSGENIFVVRNNIIYTPLAAQSILPGFTRHAVMHIARELGYEVRETPIP
REALYIADEIFLTGTAAEITPVRSVDRIPIGNEHRGPVTEALQHEYLKIVHSGEDPYNWLTFI

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=296, Percent_Identity=52.027027027027, Blast_Score=322, Evalue=1e-89,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 33946; Mature: 33946

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNSLKIWMNGELVGWSDAKIHVMSHVVHYGSSTFEGIRCYDTVKGSALLFLDEHVRRLW
CCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEHHHHHHHHH
ESSKIYRIEIPYSETEIKDAIISTIKANNHKACYVRPLVFRGQGALGVNPHRASIEVAIA
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEE
TWEWGTYLGEDVLENGVDVKVSSWHRLAPNTLPSWAKAGGNYMNSQLIKMEALSDGYAEG
EECCCHHHCHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCEEEEEHHCCCCCCC
LALDHNGYVAEGSGENIFVVRNNIIYTPLAAQSILPGFTRHAVMHIARELGYEVRETPIP
EEECCCCEEEECCCCEEEEEECCEEECCHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCC
REALYIADEIFLTGTAAEITPVRSVDRIPIGNEHRGPVTEALQHEYLKIVHSGEDPYNWL
HHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEE
TFI
EEC
>Mature Secondary Structure
MDNSLKIWMNGELVGWSDAKIHVMSHVVHYGSSTFEGIRCYDTVKGSALLFLDEHVRRLW
CCCCEEEEECCEEECCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEHHHHHHHHH
ESSKIYRIEIPYSETEIKDAIISTIKANNHKACYVRPLVFRGQGALGVNPHRASIEVAIA
CCCCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEEE
TWEWGTYLGEDVLENGVDVKVSSWHRLAPNTLPSWAKAGGNYMNSQLIKMEALSDGYAEG
EECCCHHHCHHHHHCCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCEEEEEHHCCCCCCC
LALDHNGYVAEGSGENIFVVRNNIIYTPLAAQSILPGFTRHAVMHIARELGYEVRETPIP
EEECCCCEEEECCCCEEEEEECCEEECCHHHHHHCCCHHHHHHHHHHHHCCCHHHCCCCC
REALYIADEIFLTGTAAEITPVRSVDRIPIGNEHRGPVTEALQHEYLKIVHSGEDPYNWL
HHHEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEE
TFI
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]