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The map label for this gene is recG [H]

Identifier: 21674393

GI number: 21674393

Start: 1484944

End: 1487058

Strand: Reverse

Name: recG [H]

Synonym: CT1575

Alternate gene names: 21674393

Gene position: 1487058-1484944 (Counterclockwise)

Preceding gene: 21674399

Following gene: 21674392

Centisome position: 69.01

GC content: 63.36

Gene sequence:

>2115_bases
ATGCCTCCGTTTTTACCGTTACAAGTGATCAAGGGCGTCGGTCCGAAGCGTGCGGTGATACTGGCCGAGGCGGGCATCCG
CTCGATTGCCGACCTCTACGACTGCTTCCCGCGCCGCTATCTGGACCGCACCACGATCAAGAAGATCGGCGCACTGCGCG
ACGGCGAAACCGTGACTGTTGTGGGCAGCGTGACCGGCACACGGTTCGAAGGCGGGGGACGGGGCGGTTCGCGCTTCAAG
GCGCAGATCACCGACGGTTCCGGCGTGCTCGAACTGACCTGGTTCCGCGGTGTGCACTACTTCTCGAAAACCATCCGCAG
CGGCGAGCTGGTCGCGGCGCACGGGCGTGTCACCTTTTTTGGACGCACGCCGGGAATGCAGCATCCTGACTTCGACAAGC
TTGGCGGTGATGACGAGAGCGGCGACGGGCAGCGGGACGACGAGCTGTACAAAACCGGCGCGATCATTCCGATCTATCCC
ACCACCGAGGCGATGAAGCAGGCGGGCCTCAACTCGGCGGCGCTGCGGCGTATCGTGCACCGGGCGTTCCGCGAGCACCC
GCTGCGCATCACGGAGTACCTTAGCCCGGAGATCATTGCCGCCAACAACCTGATGCCCATCGGCGAGGCGTATCGGCAGC
TCCACTTTCCCGACTCTGCCGAACAGCTCGAACGGGCGCGCTACCGCATGAAGTGGAGCGAGCTGTTCTTCGCGCAGCTC
TTTTTCGCCCTGCGCCGCACCGAGGAGCGGCGGCACCTCACCTCGGTACGGTTTGAGCGCTCCGGCGAAAAGACGGCGAG
CCTGCACGAGCGGTTGCCCTTCACCATGACTAGTGCGCAGAAGCAGGCGGTGCGCGAGATTTATCACGACCTCAAAAGCG
GACGCCAGATGAACCGCTTGTTGCAGGGCGACGTGGGGTCGGGCAAGACGCTCGTGGCGCAGTTCGCCATGACGCTCGCC
GTGGACAACGGTTTGCAGGCAGCCTTCATGGCACCGACCGAGATTCTCGCCTTTCAGCACTACGCAGGTCTCAAAAACTC
GCTTGAACCGCTCGGCATTCGGGTGGCGCTCCTGACCGGTCGCCAGAAGAAAAAGGAGCGCGAGGAAAAGCTCGCCCGGC
TCGAACGGGGCGAGATCGACATCGCCGTCGGCACCCATGCCATCATCGAGGCAGGGGTGCAGTTCCGCCGGCTCGGGCTT
GTCATCATCGACGAGCAGCATCGCTTTGGCGTGTTGCAGCGCAAGGCGTTACAGGAGAAAGCCGAGAATCCGCACGTGCT
GCTCATGACCGCCACGCCGATTCCGCGCACGCTCACGATGGGTATCTACGGCGACCTCGACGTTTCGATCATCGCCGAAA
TGCCCGCCGGGCGCAAGCCGATCCAGACGCGCCTCTGCTGTGAAGCAGAGAAGCCGGAGCTGTATCGATTATTACGGAAG
CAGATTGCCGAGGGGCGGCAGGCGTACATCGTCTATCCGCTGGTCGAGGAGTCGGAGAAGATCGATCTCAAGGCGGCCAC
CGAGAGCTACGAGCAGCTGAGGCGCGAGGTGTTTCCGGAGCTGCGGCTGGGGCTGATTCACGGCCAGCTTCCGGCGGCGG
AGAAGGAGGCGGTGATGGCAGAGTTCCGCAGTGGGCGGCTCGACATTCTCGTCGGCACGACCGTGATCGAGGTGGGCGTT
GATGTACCCAACGCAACTATCATGGTGATCGAGCATGCCGAGCGCTTCGGCATTTCGCAGCTCCACCAGCTCCGGGGGCG
CGTCGGGCGCGGCGAGCACGCCTCGTCGTGTTTTCTCGTTTACACAAAACTTACCGGTGACGCCAAAGATCGGTTGCAGG
CGATGGCTGCGACTGGCGACGGATTCCGGCTCTCCGAGATCGATTTGCAGATTCGCGGCGCAGGCAACATGCTGGGCCGC
GAGCAGTCCGGCGCGGCAAGCGGCCTCAGGATCGCCGACCTGCTTACCGATGGCGACATCATGCGCGCGGCGCGGGCGGC
GGCCTTCGAGCTGATCCGCCGCGACGAAACGCTCACACACCCCGAAAATGCCCTGATCAGGGATTATTATATGACCCACT
TCCGCAAGCGAATCTCGCTGGCTGATGTCGGGTGA

Upstream 100 bases:

>100_bases
TTCATGACCTTTGTGATTACGTTGCCTGGATGACAATAAAAAATTGATCAGGAATTAACTCTTTTTTCTGCTAATAAACA
AGCTGCGACGCCAATTCGTT

Downstream 100 bases:

>100_bases
TTGCCGGATTGCCCGATTTTCTTGCTCCATTCATATTCACCAGATGCTGTTCGTGGAAAGTGAAATGCTTATATTTTCTT
CCTTTTGGAGCTTCGCTTCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MPPFLPLQVIKGVGPKRAVILAEAGIRSIADLYDCFPRRYLDRTTIKKIGALRDGETVTVVGSVTGTRFEGGGRGGSRFK
AQITDGSGVLELTWFRGVHYFSKTIRSGELVAAHGRVTFFGRTPGMQHPDFDKLGGDDESGDGQRDDELYKTGAIIPIYP
TTEAMKQAGLNSAALRRIVHRAFREHPLRITEYLSPEIIAANNLMPIGEAYRQLHFPDSAEQLERARYRMKWSELFFAQL
FFALRRTEERRHLTSVRFERSGEKTASLHERLPFTMTSAQKQAVREIYHDLKSGRQMNRLLQGDVGSGKTLVAQFAMTLA
VDNGLQAAFMAPTEILAFQHYAGLKNSLEPLGIRVALLTGRQKKKEREEKLARLERGEIDIAVGTHAIIEAGVQFRRLGL
VIIDEQHRFGVLQRKALQEKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRKPIQTRLCCEAEKPELYRLLRK
QIAEGRQAYIVYPLVEESEKIDLKAATESYEQLRREVFPELRLGLIHGQLPAAEKEAVMAEFRSGRLDILVGTTVIEVGV
DVPNATIMVIEHAERFGISQLHQLRGRVGRGEHASSCFLVYTKLTGDAKDRLQAMAATGDGFRLSEIDLQIRGAGNMLGR
EQSGAASGLRIADLLTDGDIMRAARAAAFELIRRDETLTHPENALIRDYYMTHFRKRISLADVG

Sequences:

>Translated_704_residues
MPPFLPLQVIKGVGPKRAVILAEAGIRSIADLYDCFPRRYLDRTTIKKIGALRDGETVTVVGSVTGTRFEGGGRGGSRFK
AQITDGSGVLELTWFRGVHYFSKTIRSGELVAAHGRVTFFGRTPGMQHPDFDKLGGDDESGDGQRDDELYKTGAIIPIYP
TTEAMKQAGLNSAALRRIVHRAFREHPLRITEYLSPEIIAANNLMPIGEAYRQLHFPDSAEQLERARYRMKWSELFFAQL
FFALRRTEERRHLTSVRFERSGEKTASLHERLPFTMTSAQKQAVREIYHDLKSGRQMNRLLQGDVGSGKTLVAQFAMTLA
VDNGLQAAFMAPTEILAFQHYAGLKNSLEPLGIRVALLTGRQKKKEREEKLARLERGEIDIAVGTHAIIEAGVQFRRLGL
VIIDEQHRFGVLQRKALQEKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRKPIQTRLCCEAEKPELYRLLRK
QIAEGRQAYIVYPLVEESEKIDLKAATESYEQLRREVFPELRLGLIHGQLPAAEKEAVMAEFRSGRLDILVGTTVIEVGV
DVPNATIMVIEHAERFGISQLHQLRGRVGRGEHASSCFLVYTKLTGDAKDRLQAMAATGDGFRLSEIDLQIRGAGNMLGR
EQSGAASGLRIADLLTDGDIMRAARAAAFELIRRDETLTHPENALIRDYYMTHFRKRISLADVG
>Mature_703_residues
PPFLPLQVIKGVGPKRAVILAEAGIRSIADLYDCFPRRYLDRTTIKKIGALRDGETVTVVGSVTGTRFEGGGRGGSRFKA
QITDGSGVLELTWFRGVHYFSKTIRSGELVAAHGRVTFFGRTPGMQHPDFDKLGGDDESGDGQRDDELYKTGAIIPIYPT
TEAMKQAGLNSAALRRIVHRAFREHPLRITEYLSPEIIAANNLMPIGEAYRQLHFPDSAEQLERARYRMKWSELFFAQLF
FALRRTEERRHLTSVRFERSGEKTASLHERLPFTMTSAQKQAVREIYHDLKSGRQMNRLLQGDVGSGKTLVAQFAMTLAV
DNGLQAAFMAPTEILAFQHYAGLKNSLEPLGIRVALLTGRQKKKEREEKLARLERGEIDIAVGTHAIIEAGVQFRRLGLV
IIDEQHRFGVLQRKALQEKAENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRKPIQTRLCCEAEKPELYRLLRKQ
IAEGRQAYIVYPLVEESEKIDLKAATESYEQLRREVFPELRLGLIHGQLPAAEKEAVMAEFRSGRLDILVGTTVIEVGVD
VPNATIMVIEHAERFGISQLHQLRGRVGRGEHASSCFLVYTKLTGDAKDRLQAMAATGDGFRLSEIDLQIRGAGNMLGRE
QSGAASGLRIADLLTDGDIMRAARAAAFELIRRDETLTHPENALIRDYYMTHFRKRISLADVG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=668, Percent_Identity=42.9640718562874, Blast_Score=447, Evalue=1e-126,
Organism=Escherichia coli, GI1787357, Length=456, Percent_Identity=37.5, Blast_Score=284, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 78651; Mature: 78520

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPFLPLQVIKGVGPKRAVILAEAGIRSIADLYDCFPRRYLDRTTIKKIGALRDGETVTV
CCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VGSVTGTRFEGGGRGGSRFKAQITDGSGVLELTWFRGVHYFSKTIRSGELVAAHGRVTFF
EEECCCCEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCEEEECCEEEEE
GRTPGMQHPDFDKLGGDDESGDGQRDDELYKTGAIIPIYPTTEAMKQAGLNSAALRRIVH
ECCCCCCCCCHHHCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHHHHCCCCHHHHHHHHH
RAFREHPLRITEYLSPEIIAANNLMPIGEAYRQLHFPDSAEQLERARYRMKWSELFFAQL
HHHHHCCCCHHHHCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFALRRTEERRHLTSVRFERSGEKTASLHERLPFTMTSAQKQAVREIYHDLKSGRQMNRL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCHHHHHH
LQGDVGSGKTLVAQFAMTLAVDNGLQAAFMAPTEILAFQHYAGLKNSLEPLGIRVALLTG
HCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
RQKKKEREEKLARLERGEIDIAVGTHAIIEAGVQFRRLGLVIIDEQHRFGVLQRKALQEK
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCEEHCCEEEEECCHHHHHHHHHHHHHH
AENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRKPIQTRLCCEAEKPELYRLLRK
CCCCEEEEEECCCCCCEEEECEECCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHH
QIAEGRQAYIVYPLVEESEKIDLKAATESYEQLRREVFPELRLGLIHGQLPAAEKEAVMA
HHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHH
EFRSGRLDILVGTTVIEVGVDVPNATIMVIEHAERFGISQLHQLRGRVGRGEHASSCFLV
HHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCCEEEE
YTKLTGDAKDRLQAMAATGDGFRLSEIDLQIRGAGNMLGREQSGAASGLRIADLLTDGDI
EEECCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHH
MRAARAAAFELIRRDETLTHPENALIRDYYMTHFRKRISLADVG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PPFLPLQVIKGVGPKRAVILAEAGIRSIADLYDCFPRRYLDRTTIKKIGALRDGETVTV
CCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VGSVTGTRFEGGGRGGSRFKAQITDGSGVLELTWFRGVHYFSKTIRSGELVAAHGRVTFF
EEECCCCEECCCCCCCCEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCEEEECCEEEEE
GRTPGMQHPDFDKLGGDDESGDGQRDDELYKTGAIIPIYPTTEAMKQAGLNSAALRRIVH
ECCCCCCCCCHHHCCCCCCCCCCCCCHHHHHCCCEEEECCCHHHHHHCCCCHHHHHHHHH
RAFREHPLRITEYLSPEIIAANNLMPIGEAYRQLHFPDSAEQLERARYRMKWSELFFAQL
HHHHHCCCCHHHHCCCCEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
FFALRRTEERRHLTSVRFERSGEKTASLHERLPFTMTSAQKQAVREIYHDLKSGRQMNRL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHHHHCCHHHHHH
LQGDVGSGKTLVAQFAMTLAVDNGLQAAFMAPTEILAFQHYAGLKNSLEPLGIRVALLTG
HCCCCCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCEEEEEECC
RQKKKEREEKLARLERGEIDIAVGTHAIIEAGVQFRRLGLVIIDEQHRFGVLQRKALQEK
CHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCEEHCCEEEEECCHHHHHHHHHHHHHH
AENPHVLLMTATPIPRTLTMGIYGDLDVSIIAEMPAGRKPIQTRLCCEAEKPELYRLLRK
CCCCEEEEEECCCCCCEEEECEECCCCEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHH
QIAEGRQAYIVYPLVEESEKIDLKAATESYEQLRREVFPELRLGLIHGQLPAAEKEAVMA
HHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHH
EFRSGRLDILVGTTVIEVGVDVPNATIMVIEHAERFGISQLHQLRGRVGRGEHASSCFLV
HHCCCCEEEEECCEEEEECCCCCCCEEEEEECHHHCCHHHHHHHHHCCCCCCCCCCEEEE
YTKLTGDAKDRLQAMAATGDGFRLSEIDLQIRGAGNMLGREQSGAASGLRIADLLTDGDI
EEECCCCHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHH
MRAARAAAFELIRRDETLTHPENALIRDYYMTHFRKRISLADVG
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]