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The map label for this gene is surE

Identifier: 21674375

GI number: 21674375

Start: 1468483

End: 1469274

Strand: Direct

Name: surE

Synonym: CT1557

Alternate gene names: 21674375

Gene position: 1468483-1469274 (Clockwise)

Preceding gene: 21674374

Following gene: 21674376

Centisome position: 68.14

GC content: 58.46

Gene sequence:

>792_bases
TTGACGACAAAACCGCAGAAACCGCACATTCTTGTCTGTAATGACGACGGTATCGAAGGCCTTGGCCTGCACGCGCTGGC
TGCCTCGATGAAAAAGCTCGGCTCCGTGACGGTGGTCGCACCCGCCGAACCTCAAAGCGGCAAAAGCCACGGCATGACCC
TTGGCGAACCGCTACGCATCAGGAGGTACCAGAAAAACAACCGTTTTTTTGGCTATACCGTCTCCGGCACGCCCGTAGAC
TGCATCAAGGTGGCGCTGAGCCACATCCTCGACGCGAAACCTGACCTCATCGTTTCGGGCATCAACTATGGCAGCAACAC
CGCCATGAACAGCCTCTATTCCGGAACGGTTGCCGCCGCCCGCGAGGGCGCGATCCAGAATGTGCCATCACTTGCCTTTT
CGCTGACCACCTACGAAAACGCCGACTTCACCTACGCAGCCAAATTCGCCCGGCAACTGGCTCGCGAGGTACTCCGGCGC
GGAATGCCACCCGACACCATCCTGTCGGCCAACATTCCCAACGTGCCCGAAAAAGAGATTCGCGGCATCCTGTTCACGCG
GCAGGGGCGATCGCGATGGGAGGAGTCAACCATCGAGCGGCACGACATGTACGGCAACCCCTACTACTGGCTCGCCGGCT
CGCTCCAGTTGCACGACAATGATCTCGCGGAGGACGAATACGCTGTGCGGCACAACTATGTGGCTGTCACACCCATCACC
TGTGACATGACCGATCATCGCTTCAGAAGCGAACTCGAAACCTGGGGCCTCCAGAACACCATCAAGAAGTAA

Upstream 100 bases:

>100_bases
ACGTCAATGATTCAGCCAGGATCGACTTTACCGATACCGTGTTTTACTTCAGCCTCGGCCATGACTTCTGAGAACATCTG
AAACCATACATCGACATCTT

Downstream 100 bases:

>100_bases
GCGTGTGAACACTTTCCTTATCGACTACCAGCGCATCCGGACACCAAAAAAGGGCTTTTCGAAGCTTTTCTGCGATTACA
GCTCCGAAAGCGAGGCACGA

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTTKPQKPHILVCNDDGIEGLGLHALAASMKKLGSVTVVAPAEPQSGKSHGMTLGEPLRIRRYQKNNRFFGYTVSGTPVD
CIKVALSHILDAKPDLIVSGINYGSNTAMNSLYSGTVAAAREGAIQNVPSLAFSLTTYENADFTYAAKFARQLAREVLRR
GMPPDTILSANIPNVPEKEIRGILFTRQGRSRWEESTIERHDMYGNPYYWLAGSLQLHDNDLAEDEYAVRHNYVAVTPIT
CDMTDHRFRSELETWGLQNTIKK

Sequences:

>Translated_263_residues
MTTKPQKPHILVCNDDGIEGLGLHALAASMKKLGSVTVVAPAEPQSGKSHGMTLGEPLRIRRYQKNNRFFGYTVSGTPVD
CIKVALSHILDAKPDLIVSGINYGSNTAMNSLYSGTVAAAREGAIQNVPSLAFSLTTYENADFTYAAKFARQLAREVLRR
GMPPDTILSANIPNVPEKEIRGILFTRQGRSRWEESTIERHDMYGNPYYWLAGSLQLHDNDLAEDEYAVRHNYVAVTPIT
CDMTDHRFRSELETWGLQNTIKK
>Mature_262_residues
TTKPQKPHILVCNDDGIEGLGLHALAASMKKLGSVTVVAPAEPQSGKSHGMTLGEPLRIRRYQKNNRFFGYTVSGTPVDC
IKVALSHILDAKPDLIVSGINYGSNTAMNSLYSGTVAAAREGAIQNVPSLAFSLTTYENADFTYAAKFARQLAREVLRRG
MPPDTILSANIPNVPEKEIRGILFTRQGRSRWEESTIERHDMYGNPYYWLAGSLQLHDNDLAEDEYAVRHNYVAVTPITC
DMTDHRFRSELETWGLQNTIKK

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=248, Percent_Identity=35.0806451612903, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_CHLTE (Q8KC69)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662440.1
- ProteinModelPortal:   Q8KC69
- SMR:   Q8KC69
- GeneID:   1007226
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1557
- NMPDR:   fig|194439.1.peg.1534
- TIGR:   CT1557
- HOGENOM:   HBG600532
- OMA:   SINVIYS
- ProtClustDB:   PRK13932
- BioCyc:   CTEP194439:CT_1557-MONOMER
- BRENDA:   3.1.3.5
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 29243; Mature: 29111

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKPQKPHILVCNDDGIEGLGLHALAASMKKLGSVTVVAPAEPQSGKSHGMTLGEPLRI
CCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHE
RRYQKNNRFFGYTVSGTPVDCIKVALSHILDAKPDLIVSGINYGSNTAMNSLYSGTVAAA
EEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCHHHHH
REGAIQNVPSLAFSLTTYENADFTYAAKFARQLAREVLRRGMPPDTILSANIPNVPEKEI
HCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHH
RGILFTRQGRSRWEESTIERHDMYGNPYYWLAGSLQLHDNDLAEDEYAVRHNYVAVTPIT
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHCCEEEEEEEE
CDMTDHRFRSELETWGLQNTIKK
ECCCHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure 
TTKPQKPHILVCNDDGIEGLGLHALAASMKKLGSVTVVAPAEPQSGKSHGMTLGEPLRI
CCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHE
RRYQKNNRFFGYTVSGTPVDCIKVALSHILDAKPDLIVSGINYGSNTAMNSLYSGTVAAA
EEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHCCHHHHH
REGAIQNVPSLAFSLTTYENADFTYAAKFARQLAREVLRRGMPPDTILSANIPNVPEKEI
HCCHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHH
RGILFTRQGRSRWEESTIERHDMYGNPYYWLAGSLQLHDNDLAEDEYAVRHNYVAVTPIT
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCHHHHCCEEEEEEEE
CDMTDHRFRSELETWGLQNTIKK
ECCCHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901